Fifteen startups — with clean energy solutions involving everything from solar energy to hydrogen — are joining Rice Alliance's Clean Energy Accelerator later this summer. Photo via Getty Images

A clean energy program has announced its third cohort and named the 15 startups that were accepted into to the accelerator.

The Rice Alliance's Clean Energy Accelerator revealed its 2023 cohort that will be in the 10-week program that kicks of July 25. CEA, a hybrid program based out of the Ion, will wrap up with a Demo Day alongside the 20th Annual Rice Alliance Energy Tech Venture Forum on September 21.

The accelerator, led by Kerri Smith and Matt Peña, provides the cohort with programming, networking, and mentorship from six executives in residence — Nathan Ball, Fatimah Bello, Michael Egan, Michael Evans, Stephen Sims, and Deanna Zhang.

Since the Clean Energy Accelerator launched in 2021, the program has supported 29 ventures that have gone on to raise over $75 million in funding, identified and launched pilots, and created jobs, According to Rice, many of these companies relocated to Houston.

Class 3, which has already raised $23.3 million in funding, hails from four countries and seven states and are addressing a range of energy solutions — from advanced materials, carbon management/capture, energy storage, hydrogen, solar energy, wind energy, and more. They were selected by a screening committee consisting of more than 50 industry experts, investors, energy leaders, and entrepreneurs.

The third class, as announced by Rice Alliance, is as follows:

  • Ayrton Energy, based in Alberta, Canada, provides hydrogen storage technology that improves hydrogen transport logistics for distributed energy applications.
  • Headquartered in Massachusetts, Carbix transforms atmospheric carbon dioxide emissions into building materials using proprietary reactor technology.
  • Houston-based CryoDesalination lowers the carbon footprint and cost of removing salts and heavy metals from water and industrial effluents.
  • Digital Carbon Bank, based in Alberta, Canada, provides a carbon solution tailored for the energy industry.
  • Chandler, Arizona-based EarthEn provides compressed carbon dioxide-based energy storage and artificial intelligence solutions allowing grid owners/operators to be completely renewable.
  • H Quest Vanguard, from Pittsburgh, provides green hydrogen at a five to 10 times lower cost to users of natural gas to decarbonize industrial heat.
  • Calgary, Alberta-based Highwood Emissions Management's SaaS platform allows oil and gas companies to understand their emissions and develop robust plans to reduce them.
  • Icarus RT, from San Diego, California, improves photovoltaic efficiency while enabling useful heat energy storage.
  • Los Altos, California-based Khepra has developed a chemical manufacturing platform for the low-cost, sustainable production of agrochemicals.
  • Binghamton, New York-based Natrion’s electrolyte is a drop-in solid-state battery component that can be rapidly implemented into existing batteries.
  • Oceanways, based in London, provides low-cost, flexible and scalable zero-emission underwater "virtual pipelines" to energy producers.
  • Relyion Energy, from Santa Clara, California, is developing battery usage and intelligence solutions with deeper data and insights for retired electric vehicle batteries.
  • Massachusetts-based Triton Anchor provides a more cost-effective anchoring solution for offshore clean energy with minimal environmental impact.
  • TROES, from Markham, Ontario, provides a 4-in-1 microgrid solution with integrated hardware and software for a streamlined energy storage experience.
  • Mexico City-based Tycho Solutions supports clean energy project developers by saving time and money during the critical project-siting process.
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Houston scientists create platform for long-lasting, precise drug delivery

drug breakthrough

A team of Rice University scientists has developed a new drug delivery platform that researchers say can slow the rate of drug release, which has major implications for drug efficacy and potentially cancer immunotherapy.

The research was published in Nature Nanotechnology, and supported by the National Science Foundation, the National Institutes of Health, the Cancer Prevention and Research Institute of Texas and the Welch Foundation.

In the study, the team demonstrated how a peptide hydrogel functions as a three-dimensional network that controls the rate of release across a range of medication types, including small-molecule drugs and biologics such as insulin and antibodies. The system, called self-assembling boronate ester release (SABER), uses reversible chemical bonds between the peptide and the drug molecule to extend the duration of drug release. Instead of passing quickly through the net, the drug gets temporarily “stuck” each time it binds to the peptide, which slows its passage out of the hydrogel, according to Rice.

The researchers formulated a tuberculosis-treating drug into a hydrogel. They used it to treat infected mice with a single injection of the drug-laden hydrogel. In the test, the hydrogel outperformed almost daily oral administration of the medication over two weeks. Insulin packaged in SABER hydrogels successfully controlled blood sugar levels in diabetic mice for six days in another set of experiments.

Brett Pogostin, a Rice doctoral alum who led the development of SABER and served as first author of the study, began working on self-assembling peptides as an undergraduate student at Rice. Jeffrey Hartgerink, a professor of chemistry and bioengineering at Rice, and Kevin McHugh, associate professor of bioengineering and chemistry and a Cancer Prevention and Research Institute of Texas scholar, advised Pogostin and served as corresponding authors on the study.

Pogostin’s work aimed to bridge foundational materials research and biomedical applications. SABER was inspired by a drug delivery course taught by McHugh, where Pogostin learned about dynamic covalent bonds used in glucose sensing, where the bonds reversibly form and break apart. That quality inspired Pogostin to adapt the concept for drug delivery.

“Brett really drove this project in a way that is, in my experience, unusual for a graduate student,” Hartgerink said in the news release. “It’s a very versatile approach. You can make both small-molecule drugs and very large biologics sticky with the type of chemistry that Brett developed.”

The team demonstrated the platform in two different use cases with Tuberculosis and Type 1 diabetes, with SABER simplifying dosing and enhancing the efficacy of the drugs. Hartgerink described the current SABER system as “generation one,” and plans to work to make it widely applicable. He is looking into how SABER could be applied to cancer immunotherapy.

“What I’m really passionate about right now is cancer prevention — trying to think about how we can use materials to prime the immune system to prevent cancer from ever happening as opposed to just treating it,” Pogostin added.

10 Houston companies clock in with best corporate cultures, says Forbes

Where to Work

Two of Houston's biggest medical institutions – Houston Methodist and MD Anderson Cancer Center – have just landed top-50 spots on Forbes' new ranking of "America's Best Employers for Company Culture." The report highlighted eight more Houston-area companies for their inspiring company culture.

Forbes partnered with market research firm Statista to survey over 218,000 workers at companies with at least 1,000 employees throughout the U.S, and relied on data from the past three years of employee surveys (with an emphasis on the most recent data and recommendations from current employees). Companies don't pay to be included, Forbes additionally noted.

Among the final list of 600 U.S. companies, 30 Texas employers were praised for providing "a unifying company culture that inspires a sense of purpose and loyalty among employees."

Houston Methodist climbed into the No. 15 spot nationally and outranked all other Texas companies on the list, while MD Anderson ranked 47th nationwide. Both institutions have dominated U.S. News' annual rankings of the best Texas hospitals for over a decade, proving exactly how having a great company culture can also improve the service provided to patients.

MD Anderson Cancer Center MD Anderson Cancer Center has been the No. 1 best cancer hospital in the U.S. for over a decade. Photo courtesy of KVUE

According to the report's research, employers with a successful company culture don't rely on "surface-level perks" such as free lunches, wellness apps, and flex days to inspire employee engagement. Instead, employers that focused on conflict resolution and coaching their managers saw a reduction in employee burnout and an increase in "perceptions of fairness and leadership care."

"In fact, the researchers noted that when 'senior leaders changed how they led — how they ran meetings, gave feedback, made decisions and responded to challenge — trust scores rose by an average of 26 percent,'" the report said.

The eight other Houston-area companies that earned national acclaim for their company culture are:

  • No. 220 – Stewart Info Services
  • No. 325 – BP
  • No. 332 – Baylor College of Medicine
  • No. 492 – Chevron Phillips Chemical, The Woodlands
  • No. 525 – Insperity
  • No. 558 – NRG Energy
  • No. 586 – Waste Management
  • No. 593 – LyondellBassell

Other Texas employers with great company culture:

Elsewhere in Texas, 15 North Texas companies and five Central Texas companies were included on Forbes' list of employers with the best company culture.

The three Austin-area companies that earned spots on the list include Austin Community College District (No. 56), Round Rock-based Dell Technologies (No. 207), and Keller Williams Realty (No. 352).

The two San Antonio-based companies that made the cut are beloved Texas grocery chain H-E-B (No. 445), and municipal electric utility company CPS Energy (No. 551).

The 15 Dallas-Fort Worth-based companies that made the list include:

  • No. 58 – The Container Store, Coppell
  • No. 73 – Lewisville Independent School District, Lewisville
  • No. 117 – Southwest Airlines, Dallas
  • No. 123 –Topgolf, Dallas
  • No. 170 – McKesson, Irving
  • No. 190 – Kimberly-Clark, Irving
  • No. 245 – Jacobs Solutions,Dallas
  • No. 312 – Brinker International, Coppell
  • No. 350 – Texas Health Resources, Arlington
  • No. 482 – Toyota North America, Plano
  • No. 562 – Dallas Area Rapid Transit (DART), Dallas
  • No. 567 – AT&T, Dallas
  • No. 569 – Energy Transfer, Dallas
  • No. 591 – American Airlines Group, Fort Worth
  • No. 597 – Aimbridge Hospitality, Plano
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This article originally appeared on CultureMap.com.