Did you know that you can order an eco-conscious burger in Houston? Photo courtesy of Hopdoddy

Hearty Austin-based chain Hopdoddy Burger Bar has unveiled a new lineup of regenerative burgers that are supposed to be better for the planet and the consumer.

The term "regenerative burger" could cause a few head-scratches: Some may think of lab-grown or 3D-printed meat, while others think of plant-based alternatives but it’s neither. It is grass-fed meat, sourced a bit differently. "Regenerative farming" is a term used to describe farming and grazing practices that claim to restore and rebuild degraded soil, resulting in better-quality air and water.

Hopdoddy’s vice president of culinary Matt Schweitzer explained that it all began with with a sense of obligation to do better as a brand for the consumers and the ecosystem.

“We felt like we could really take a stand and look to move our entire supply chain in a regenerative fashion, so we could really be proud of the work we’ve done and we could hopefully leave the animals, the farmers, the ranchers, the native grasslands, and our planet a better place than before we started,” says Schweitzer.

The new menu items include the "Roosevelt Burger" with grass-fed regenerative bison; the "Nashville Hot Sandwich" with regenerative raised chicken; the "Regenerative Royale," which is a play on a classic double quarter-pounder with cheese; the "Mother Nature" with grass-fed regenerative beef; and the "Buffalo Bill" also uses regenerative bison, but appears not to be grass-fed.

The five burgers are available at all Hopdoddy locations nationwide. The beef and bison are sourced from Texas-based regenerative company Force of Nature, while the chicken is from Cooks Venture.

With this launch, Hopdoddy removes all plant-based meat substitutes from its menu, significantly reducing the options for vegans and vegetarians. The company felt the ingredients and ethos of the alternative meats — describing some such as Beyond Meats as "falsely advertised" regarding nutrition in a press release — no longer aligned with its values and mission. However, the house-made veggie patty remains on the signature "El Bandito" burger.

Schweitzer says the regenerative burgers have received positive feedback, as people are excited to know where their food comes from, how it gets to their table, and what type of impact it causes. Regarding the future of regenerative meat, he says there is no doubt it could become mainstream soon.

“I think the flavor profile, the eating experience, the story, the mission, the purpose, really speaks for itself," says Schweitzer. "So, I really think it’s a matter of time until 'regenerative' is talked about in the same way that 'organic,' or 'sustainable,' or those type of buzzwords are talked about."

To further show its commitment to regenerative agriculture, Hopdoddy is also one of the sponsors of Common Ground, a documentary about the pioneers of the regenerative movement, premiering October 4 in Austin. The "uplifting" film, according to a release, features well-known actors Laura Dern, Rosario Dawson, Jason Momoa, Woody Harrelson, Ian Somerhalder, and Donald Glover, emphasizing that this motley crew does share one thing in common: a strong belief in regenerative agriculture.

For more information about the new regenerative burgers, visit hopdoddy.com.

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This article originally ran on CultureMap.

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Houston scientists create first profile of Mars’ radiant energy budget, revealing climate insights on Earth

RESEARCH FINDINGS

Scientists at the University of Houston have found a new understanding of climate and weather on Mars.

The study, which was published in a new paper in AGU Advances and will be featured in AGU’s science magazine EOS, generated the first meridional profile of Mars’ radiant energy budget (REB). REB represents the balance or imbalance between absorbed solar energy and emitted thermal energy across latitudes. An energy surplus can lead to global warming, and a deficit results in global cooling, which helps provide insights to Earth's atmospheric processes too. The profile of Mars’ REB influences weather and climate patterns.

The study was led by Larry Guan, a graduate student in the Department of Physics at UH's College of Natural Sciences and Mathematics under the guidance of his advisors Professor Liming Li from the Department of Physics and Professor Xun Jiang from the Department of Earth and Atmospheric Sciences and other planetary scientists. UH graduate students Ellen Creecy and Xinyue Wang, renowned planetary scientists Germán Martínez, Ph.D. (Houston’s Lunar and Planetary Institute), Anthony Toigo, Ph.D. (Johns Hopkins University) and Mark Richardson, Ph.D. (Aeolis Research), and Prof. Agustín Sánchez-Lavega (Universidad del País, Vasco, Spain) and Prof. Yeon Joo Lee (Institute for Basic Science, South Korea) also assisted in the project.

The profile of Mars’ REB is based on long-term observations from orbiting spacecraft. It offers a detailed comparison of Mars’ REB to that of Earth, which has shown differences in the way each planet receives and radiates energy. Earth shows an energy surplus in the tropics and a deficit in the polar regions, while Mars exhibits opposite behavioral patterns.

The surplus is evident in Mars’ southern hemisphere during spring, which plays a role in driving the planet’s atmospheric circulation and triggering the most prominent feature of weather on the planet, global dust storms. The storms can envelop the entire planet, alter the distribution of energy, and provide a dynamic element that affects Mars’ weather patterns and climate.

The research team is currently examining long-term energy imbalances on Mars and how it influences the planet’s climate.

“The REB difference between the two planets is truly fascinating, so continued monitoring will deepen our understanding of Mars’ climate dynamics,” Li says in a news release.

The global-scale energy imbalance on Earth was recently discovered, and it contributes to global warming at a “magnitude comparable to that caused by increasing greenhouse gases,” according to the study. Mars has an environment that differs due to its thinner atmosphere and lack of anthropogenic effects.

“The work in establishing Mars’ first meridional radiant energy budget profile is noteworthy,” Guan adds. “Understanding Earth’s large-scale climate and atmospheric circulation relies heavily on REB profiles, so having one for Mars allows critical climatological comparisons and lays the groundwork for Martian meteorology.”

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This article originally ran on EnergyCapital.

Houston startup secures $22.5M to innovate cell therapy to fight cancer

fresh funding

A promising cell therapy company has raised its latest funding round — to the tune of $22.5 million.

Indapta Therapeutics, which has a dual headquarters in Houston and Seattle, is a clinical stage biotechnology and next-generation cell therapy company focused on the treatment of cancer and autoimmune diseases. The company announced it has closed a $22.5 million round of new financing to accelerate the clinical development of its differentiated allogeneic Natural Killer cell therapy.

"This funding will enable us to generate significant additional data in our ongoing trial of IDP-023 in cancer as well as initial data from our first trial in autoimmune disease," Mark Frohlich, Indapta’s CEO, says in a news release.

Indapta has completed enrollment in the safety run-in portion of the Phase 1 clinical trial of IDP-023 in Non-Hodgkin’s Lymphoma and Multiple Myeloma, according to the company. The patients received up to three doses of IDP-023 without and with interleukin (IL)-2.

Completing the round were current investors RA Capital Management, Bayer's impact investment arm Leaps, Vertex Ventures HC, Pontifax, and the Myeloma Investment Fund, the venture philanthropy subsidiary of the Multiple Myeloma Research Foundation. Earlier in December, Indapta announced a collaboration with Sanofi to explore the combination of its allogeneic g-NK cell therapy IDP-023 with Sanofi’s CD38 that targets the monoclonal antibody, Sarclisa (isatuximab).

"Preliminary results of IDP-023 in cancer are encouraging and we look forward to initiating our Phase 1 trial for multiple sclerosis in Q1 2025,” Frohlich continues. “This financing, together with our recently announced collaboration with Sanofi, highlights the promise of our differentiated platform.”

Also in August, Indapta announced a FDA clearance of its IND of IDP-023 in combination with ocrelizumab in progressive MS.


Mark Frohlich is the CEO of the Houston- and Seattle-based company. Photo courtesy of Indapta Therapeutics

Houston startup's revolutionary automotive recycling tech to begin commercial operations

houston innovators podcast episode 267

Vibhu Sharma observed a huge sustainability problem within the automotive industry, and he was tired of no one doing anything about it.

"Globally, humans dispose 1 billion tires every year," Sharma says on the Houston Innovators Podcast. "It's a massive environmental and public health problem because these tires can take hundreds of years to break down, and what they start doing is leaking chemicals into the soil."

Today, 98 percent of all tires end up in landfills, Sharma says, and this waste contributes to a multitude of problems — from mosquito and pest infestation to chemical leaks and fire hazards. That's why he founded InnoVent Renewables, a Houston-based company that uses its proprietary continuous pyrolysis technology to convert waste tires into valuable fuels, steel, and chemicals.

While the process of pyrolysis — decomposing materials using high heat — isn't new, InnoVent's process has a potential to be uniquely impactful. As Sharma explains on the show, he's targeting areas with an existing supply of waste tires. The company's first plant — located in Monterrey, Mexico — is expected to go online early in the new year, an impressive accomplishment considering Sharma started his company just over a year ago and bootstrapped the business with only a friends and family round of funding.

"It's about 16 months or so from start to commercial operations, which is phenomenal when you consider what it takes to build and operate a chemical or petrochemical facility," Sharma says.

Currently, with the facility close to operations, Sharma is looking to secure customers for the plant's products — which includes diesel, steel, and carbon black — and he doesn't have to look too far out of the automotive industry for his potential customer base. Additionally, the plant should be net zero by day one, since Sharma says he will be using the output to fuel operations.

While the first facility is in Mexico, Sharma says they are already looking at potential secondary locations with Texas at the top of his list. Houston, where Sharma has worked for 26 years, has been a strategic headquarters for InnoVent.

"When it came to doing the research and development, we were able to work with experts in the Houston and Texas areas to test out our idea and validate it," Sharma says. "One thing that gets under appreciated about Houston is how well it's connected to the rest of the world. There are so many direct connections between Houston and Latin America, as well as Europe, Middle East, and Asia."

"I also find that the Houston ecosystem is very supportive of new companies and helping them grow," he adds.