City of Houston opens applications for 2023 business competition

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Small businesses in Houston can apply for the annual Liftoff Houston competition. Photo via liftoffhouston.smapply.org

The City of Houston opened applications for its annual Liftoff Houston Startup Business Plan Competition, which helps local founders bring their months-old companies to new heights.

Now in its 11th year, the competition and educational program awards $10,000 in seed money to three founders after completing a four-month-long workshop series that culminates in a Pitch Day. Winners are named in three categories: Innovation, Product and Service.

Applications must be received by 4 p.m. on Friday, August 4. And Pitch Day will be held on November 18. To be eligible for the competition, applicants must live in Houston and operate their businesses here. Businesses must have only been in operation for less than a year and show verifiable revenue that does not exceed $10,000. Founders who do not meet these criteria are eligible for Liftoff's Educational Pathway track that does not include the competition portion of the program.

“For 11 years, Liftoff Houston has empowered participants to achieve financial mobility through entrepreneurship,” Mayor Sylvester Turner said in a statement. “These participants have become key drivers to the success of Houston’s economy, and they have contributed to our communities by creating jobs and by providing much needed goods and services.”

Liftoff Houston is sponsored by Capital One Bank and administered by the Houston Public Library and the City's Office of Business Opportunity. According to a statement, the program has helped serve historically marginalized populations in Houston. In last year's cohort, 95 of participants identified as people of color, 77 percent were female, 44 percent had no college degree and 54 percent made less than $50,000.

Last year's winners in the Innovation, Product and Service were:

  • Innovation: Aditya Aggarwal, founder of Maritime XR, which aims to supplement conventional maritime training with virtual reality simulations.
  • Product: Hannah Le, founder of RE.STATEMENT, a marketplace for designers to upcycle old fashion into wearable art
  • Service: Natasha Roberts, founder of ActIVate Drip Spa, which provides medical-grade IV drips that help eliminate toxins and aid hydration and recovery

"I wanted to see how far I could go," Le told Innovation Map earlier this year. "I had pitched before, but this was the first time that I was onstage and I just felt like I belonged there."

Le shared more about the founding of RE.STATEMENT and how Liftoff Houston impacted her business in an episode of the Houston Innovators Podcast




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This week's roundup of Houston innovators includes Hannah Le of RE.STATEMENT, Misha Govshteyn of MacroFab, and Kelli Newman of Newman & Newman Inc. Photos courtesy

3 Houston innovators to know this week

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Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from sustainable fashion to tech manufacturing — recently making headlines in Houston innovation.

Hannah Le, founder of RE.STATEMENT

Hannah Le founded RE.STATEMENT to provide a much-needed platform for sustainable fashion finds. Photo courtesy of RE.STATEMENT

It's tough out there for a sustainable fashion designer with upcycled statement pieces on the market. First of all, there historically hasn't been a platform for designers or shoppers either, as Hannah Le explains on this week's episode of the Houston Innovators Podcast.

"Most designers give up if they haven't sold an item within three months," Le says. "That's something RE.STATEMENT has dedicated its business model to — making sure that items sell faster and at a higher value than any other marketplace."

RE.STATEMENT won one of the city of Houston's startup competition, Liftoff Houston's categories last year. Le shares what's next for the early-stage company on the show. Read more and listen to the episode.

Misha Govshteyn, CEO of MacroFab

MacroFab has secured fresh investment to the tune of $42 million. Photo courtesy of MacroFab

MacroFab, a Houston-based electronics manufacturing platform, has announced $42 million in new growth capital. The company was founded by Misha Govshteyn and Chris Church, who built a platform that manage electronics manufacturing and enables real-time supply chain and inventory data. The platform can help customers go from prototype to high-scale production with its network of more than 100 factories across the continent.

“Electronics manufacturing is moving toward resilience and flexibility to reduce supply chain disruptions,” says Govshteyn, MacroFab’s CEO, in a news release. “We are in the earliest stages of repositioning the supply chain to be more localized and focused on what matters to customers most — the ability to deliver products on time, meet changing requirements, and achieve a more sustainable ecological footprint. MacroFab is fundamental to building this new operating model.”

The company has seen significant growth amid the evolution of global supply chain that's taken place over the past few years. According to the company, shipments were up 275 percent year-over-year. To keep up with growth, MacroFab doubled its workforce, per the release, and opened a new facility in Mexico. Read more.

Kelli Newman, president of Newman & Newman Inc.

In her guest column, Kelli Newman explains how to leverage communications at any stage your company is in. Photo courtesy of Newman & Newman

Kelli Newman took actionable recommendations from investors, customers, advisers, and founders within Houston to compose a guest column with key observations and advice on leveraging communications.

"The significance of effective communication and its contribution to a company’s success are points regularly stressed by conference panelists and forum speakers," she writes. "Yet for many founders it’s advice that fuels frustration for how to make communications a priority with a lack of understanding of the practice." Read more.

Hannah Le founded RE.STATEMENT to provide a much-needed platform for sustainable fashion finds. Photo courtesy of RE.STATEMENT

This Houston entrepreneur is enabling fashion upcycling for more sustainable style

houston innovators podcast episode 170

When shopping online one day, Hannah Le saw a need for a platform that allowed transactions between upcycling fashion designers and shoppers looking for unique, sustainable pieces.

Le created RE.STATEMENT, an online shopping marketplace for upcycled clothing. Before RE.STATEMENT, designers were limited to Etsy, which is focused on handmade pieces, or Poshmark and Depop, which are dedicated to thrift finds. Upcycle fashion designers didn't have their own, unique platform to sell on — and, likewise, shoppers were scattered across sites too.

"These marketplaces are really good for what they do," Le says on this week's episode of the Houston Innovators Podcast, "but, whenever I think of someone looking for something unique and sustainable, it's hard for me to imagine finding that on these marketplaces."

The platform soft launched in December with 25 upcycling designers and over 1,200 buyers that had been on the company's waitlist for almost nine months. Now that the site is live, Le hopes to give both buyers and sellers quick access to transactions.

"Most designers give up if they haven't sold an item within three months," Le explains. "That's something RE.STATEMENT has dedicated its business model to — making sure that items sell faster and at a higher value than any other marketplace."

Le says that she started with buyers to see what exactly they were looking for, then she searched and found the designers looking to sell their pieces, and the current platform is dynamic and flexible to the needs of users within her community.

"Even today, it changes every single day depending on how users are interacting with the website and what sellers are saying that they need — really communicating with buyers and sellers is how the marketplace is evolving," she says.

RE.STATEMENT's ability to quickly evolve has been due to its early stage, Le explains on the show. She's not yet taken on institutional funding or hired anyone else other than tech support. She says this allows her to quickly make changes or try out new things for users.

"For me, there are still so many things I want to prove to myself before I bring others involved," she says. "To start, it's coming up with new opportunities for buyers to interact with the website so that we can keep learning from them."

Le has already proven some success to herself. Last year, she took home one of three prizes offered at the city's Liftoff Houston competition. The contest, which gives Houston entrepreneurs pitch practice and mentorship, awarded RE.STATEMENT $10,000 for winning in the product category.

"I wanted to see how far I could go," Le says of the competition where she got to introduce her business to Mayor Sylvester Turner and a whole new audience of people. "I had pitched before, but this was the first time that I was onstage and I just felt like I belonged there."

Le shares more about her vision for RE.STATEMENT and the integral role Houston plays in her success on the show.


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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

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