The winner of the contest will be announced at a Rockets game in early April. Courtesy of Greater Houston Convention and Visitors Bureau

It's game on for Houston startups looking to compete in the Launchpad contest backed by BBVA USA and the Houston Rockets.

Houston startups have until February 28 to submit their companies for the competition. Judges from BBVA and the Rockets will select four by late March, and fans will vote on their favorite company. The winner will be presented with a $10,000 check at a Rockets game in late April. The winning startup will also receive consultations with Rockets and BBVA USA executives.

It's the fourth time BBVA has sought out entrepreneurs, but last year the organization revamped the program to focus on technology-driven startups.

"Over the past three years, we have been proud to partner with BBVA to highlight small businesses in Houston and their contribution to our economy," says Rockets Chief Revenue Officer Gretchen Sheirr. "Entering its fourth year, the Launchpad contest seeks nominees focused on using best in class digital strategies to enhance their small business. We look forward to reviewing submissions and honoring the great work that is being done by these businesses in our community.

BBVA's new Houston CEO Dillan Knudson, who was promoted to his new position in November, is excited for his inaugural involvement in the contest.

"It's extremely exciting to collaborate with the Rockets for the first time, and for such a great initiative that helps Houston's thriving small business scene," says Knudson. "Part of my new role is to create opportunities and financial freedom for Houston's communities through the bank's ample resources, and to do that in collaboration with a staple organization of this city is an honor."

Houston-based Hamper, which makes dry cleaning convenient, won the Rockets and BBVA Compass' LaunchPad competition. Courtesy of Hamper

Last year, Launchpad's winner was Hamper. Hamper's co-founder and CEO Safir Ali started his company to use technology to optimize the dry cleaning business and compares Hamper to the "Red Box of dry cleaning." The win was big for Hamper's future.

"It was an absolute pleasure to be recognized by BBVA and the Houston Rockets as the winner of the 2019 Launchpad Contest," says Ali in the release. "It was a very exciting moment for Hamper, and we are very grateful to have the opportunity to be recognized in our community. Many thanks to both BBVA and the Houston Rockets for empowering Houston businesses and giving them such a great platform to be recognized for their efforts, and for playing an active role in empowering entrepreneurship in Houston."

The winner of the contest will be announced at a Rockets game in early April. Courtesy of Greater Houston Convention and Visitors Bureau

BBVA Compass and the Houston Rockets team up to launch revamped startup contest

small biz Slam dunk

Houston startups have a chance at $10,000 thanks to the Houston Rockets and BBVA Compass' LaunchPad Contest. The application process begins on February 19 and concludes on March 5.

In its third installment, the contest is doing things a little differently this year. Previously, small businesses had to respond to questions about their organization and what they would do with the prize money. This year, with a special focus on startups, applicants are also being asked about using new technology to increase productivity.

"BBVA Compass is in a unique position and we want to leverage that to help elevate entrepreneurship through digital capabilities," says BBVA Compass Houston CEO Mark Montgomery in a release. "We are a leader in the financial industry's digital transformation, and have won multiple awards because of our innovative products and services in that realm. We want to create ample opportunities for a rising business through that industry-leading expertise. The Rockets are excellent teammates, and we are excited to unveil this new version of our collaborative contest with them."

Following the application process, BBVA and the Rockets will select four finalists before opening the contest up to fans to pick their favorite. The winner will then be announced at a game in early April. The winning company will receive, in addition to the $10,000, consultations with both BBVA and the Rockets executives.

"We are excited to partner with BBVA again for this annual contest," says Rockets Chief Revenue Officer Gretchen Sheirr in the release. "They have been best in class in their industry with their digital strategy, so it's fantastic that they will be providing an opportunity for other businesses to thrive in this space. We look forward to reviewing our fans' contest submissions and seeing the great work being done by startup businesses in our great city."

Last year's Launchpad winner was Buy On Purpose, according to a release. The office supply delivery company on the northside of town boasts same-day delivery and donates half its profits to organizations fighting human trafficking, clean water initiatives, and other causes.

Learn more about last year's winner here:

BBVA Compass and the Houston Rockets announce Buy On Purpose as its small business contest winnerwww.youtube.com

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”