These are the Houston companies headed to MassChallenge Texas in Austin

Texas road trip

A handful of Houston startups will be bouncing back and forth to Austin for the second annual MassChallenge Texas accelerator. Getty Images

It's the second cohort for Boston-based MassChallenge Texas in Austin, and this year's 74 selected finalists are well represented by Houston.

"Coming from an extremely competitive application pool, the startups in our second Austin-based cohort represent an incredibly high bar of creativity and talent, all of who are poised to make an impact," says Mike Millard, managing director of MassChallenge Texas, in a release. "This year's program will offer the finalists innovation at scale with direct access to resources through our programs in Houston and Austin, and our community around the state. Through these channels, startups will have more opportunities to test and validate their ideas with partners while creating meaningful engagements to help them get to pilot or pivot as fast as possible."

While there is the upcoming MassChallenge Texas inaugural Houston cohort, these seven companies opted for a spot in the Austin-based cohort where the stakes are higher and cash prizes are on the line — $500,000, the largest equity-free cash prize in Texas, to be precise. (Houston's inaugural set of prizes reportedly don't included money.)

These are seven of the Houston-related companies that will be trekking back and forth to Austin from June until October.

crewcollar

Getty Images

It's crewcollar's mission to optimize hiring for industrial and blue-collar jobs, simplifying the entire process from curated job posts to paperwork filing. The company is based just outside of Houston in Missouri City.

"We are super excited to be joining MassChallenge Texas, and know that this experience will help us take it to the next level," says M. Siler, CEO and founder, in a release.

GotSpot Inc.

Courtesy of GotSpot

Houston-based GotSpot is Reda Hicks solution to finding temporary space quickly and easily — in a way that benefits all sides of the transaction. The model is like AirBnb, but for retail, meeting, and even emergency space. The corporate lawyer has grown the platform over the past few years and the MassChallenge opportunity is another move in the right direction. Click here to read more about Hicks and GotSpot.

Grant Source

Photo via grantsourceapp.com

Grant Source is like the magic genie to help organizations find funding through grants and opportunities. The Houston startup has a database of opportunities and can help match businesses with appropriate grants to apply to — all within the Grant Source mobile app.

Guzo

Getty Images

Guzo is the tool every traveler has dreamed up. The Houston-based app connects travelers — not just in the planning phase — but throughout the travel process. The company was created by two brothers — Joshua and Gordon Taylor — and is the recreation of Croozen, formerly a long-distance carpool app.

"One of the things that got Gordan and I excited in the beginning of Croozen was just the idea of someone else in the car with you and that shared experience," Joshua Taylor tells InnovationMap in a previous interview about revamping Croozen as Guzo. "Looking past that, just being focused on the car was hindering us. Let's divorce the car and focus on travel as a whole."

Lazarus 3D

Photo via laz3d.com

Practice makes perfect, and surgeons should be as close to perfect as possible, right? Lazarus 3D uses 3D printing to make realistic body parts and organs so that surgeons can rehearse their surgeries before ever slicing into a patient. The company is conveniently located in the Texas Medical Center.

Pilot Plus

Photo via pilotplus.com

The trucking industry needs a rebrand. It's a tireless job that's go-go-go, and the unappealing nature of the career isn't ideal. Pilot Plus puts the humanity back in the process that benefits the driver and makes for bragging rights for the company employing the trucker. The logistics company allows for a system of drivers that work together for the long haul so that drivers can actually spend time resting in their own homes.

Topl

Courtesy of Topl

Topl's MassChallenge bio lists their HQ in the Netherlands, but the blockchain startup founded by three Rice University alumni has some of its operations right here in town. Topl has a goal of using blockchain technology to connect the dots and enhance transparency in various applications from retail to even being able to track the success of investments or scholarships.

"We are a generation that wants a story," Kim Raath, president at Topl, tells InnovationMap in a previous interview. "We want an origin, and don't want to be fooled. And, because you might be able to reduce the cost by having this transparency, you might be able to bring down the cost on both sides."


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Houston biotech company tests hard-to-fight cancer therapeutics

fighting cancer

A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.

Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

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This story originally appeared on our sister site, EnergyCapitalHTX.

Houston Public Library to open new state-of-the-art TECHLink center in 2025

Innovation Station

Work is underway for a new state-of-the-art TECHLink space from Houston Public Library (HPL). The free center for innovators and creatives is expected to open in fall 2025 at Vinson Neighborhood Library this year.

The new 3,480-square-foot space will replace the branch’s existing HPL Express area, which closed January 25 in preparation for construction. This will be HPL's fifth TECHLink center, and it will serve one of South Houston's busiest libraries, notes a release.

“I always look forward to seeing our customers’ creative wheels turning and formulating plans once they recognize all of the technologies and equipment that they can freely access,” Roland Lemonius, TECHLink Division Manager, said in a news release.

TECHLink Vinson will include HPL's largest TECHLink video studio and also a dedicated studio/set for podcasts and vloggers.

HPL TECHLinkVideo studio at TECHLink Dixon. Courtesy of HPL

It will also feature a music recording studio, an editing lab, and a Makerspace lab for 3D printing and laser engraving. Virtual and in-person training opportunities will be available in a training lab in the future, according to HPL.

For kids, the Tiny Techs Zone offers a dedicated area to educate youth on 3D printing and robotics.

“Being able to enhance their quality of life in this way along with our other library services is very rewarding,” Lemonius added in the release.

TECHLink Vinson will join four other locations:

  • TECHLink Alief
  • TECHLink Dixon
  • TECHLink Scenic Woods
  • TECHLink Walker
Find a virtual tour of the Dixon location here.


croployaltyshopping_cartlocal_librarydeleteTECHLINKTECHLink Vinson will join four other locations, including DIxon. Courtesy of HPL


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