Rice Alliance names 10 most promising energy technology companies at its annual forum

Best of the best

These 10 companies are ones to look out for. Getty Images

From fast-charging batteries and hydrogen fuel alternatives to metals recycling and artificial intelligence-driven data tools, energy tech startups have a lot to offer the industry.

After nearly 60 pitches, the Rice Alliance for for Technology and Entrepreneurship named 10 startups to look out for in the energy industry. The announcement was made at the conclusion of the annual Energy and Clean Technology Venture Forum hosted at Rice University on September 11.

Of the 10, five hail from Houston. Check out this year's energy tech startups to look out for.

Sensytec

Fresh off a win from Houston's inaugural MassChallenge Texas cohort, Houston-based Sensytec again scored big. Sesnsytec's technology is known as the "smart concrete" because they've created a device that can be embedded into concrete and monitor its structure in real time. The company was founded out of the University of Houston in 2016 by Ody de la Paz.

Rheidiant

Another Houston-based company, Rheidiant uses industrial Internet of Things to optimize data from the pipelines. As a result, Rheidiant's technology can increase productivity, reduce leaks, quickly respond in emergency situations, and enhance visibility in the field. Rheidiant was founded in 2014 by CEO Murat Ocalan.

Nesh

Houston-based Nesh has created a smart assistant for oil and gas. Using artificial intelligence, Nesh can answer any question from an oil and gas employee to improve their decision-making process and cut down on the time it takes to find solutions. Nesh was founded in 2018 by Sidd Gupta and the company closed its seed round in April.

GBatteries

GBatteries, based in Ottawa, Canada, is changing the lithium battery charging game. With a mission of revolutionizing the electric car industry, GBatteries has created an artificial intelligence-backed technology that can charge a lithium battery to half full in 5 minutes. The company has 10 patents granted and 28 pending and has pilot programs in the works with automotive companies.

HARBO Technologies

Tel Aviv, Israel-based HARBO Technologies bills itself as the fastest and most effective oil spill response system in the world.The company's T-Fence system can be deployed quickly and by a team of as little as two people. HARBO was founded in 2013 by CEO Boaz Ur and has raised three rounds of funding, according to Crunchbase.

Sensorfield

It's not the first time Houston-based Sensorfield has been deemed most promising by the Rice Alliance. The company has created easy to install, wireless devices for monitoring throughout the industrial process. In May, the startup was selected for Chevron Technology Ventures' Catalyst Program.

MolyWorks Materials Corp.

California startup, MolyWorks Materials Corp., is improving the way industrial materials are recycled by building by creating a network of distributed recycling and additive manufacturing. Old metals materials go in, and metallic powder for manufacturing new products come out.

Lilac Solutions

Oakland, California-based Lilac Solutions exists to enhance lithium production as the demand rises with the growth of the electronic vehicles industry. Lilac has created a unique ion exchange technology that can lower the cost of lithium production while increasing the speed. The company is currently operating pilot programs.

Mission Secure

Mission Secure Inc. has created an industrial control system that can protect energy companies from potential cybersecurity threats as well as educate on the process. Based in Charlottesville, Virginia, MSI is venture backed and serving clients in Houston.

Syzygy Plasmonics

Houston-based Syzygy Plasmonics is fresh off a $5.8 million series A funding round it closed in August. The company is creating a hydrogen fuel cell technology that produces a cheaper source of energy that releases fewer carbon emissions. The hydrogen-fueled technology originated out of research done over two decades by two Rice University professors, Naomi Halas and Peter Nordlander. Earlier this summer, the Rice Alliance named Syzygy a most promising startup at the Offshore Technology Conference.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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