For the second year, Curtis Jackson's program supported Houston student entrepreneurs. Photo courtesy of G-Unity

The 50 Cent-backed high school entrepreneurship program wrapped up its second year of operation after helping over 100 Houston-area students build their small business plans.

G-Unity Business Labs, sponsored by Curtis James Jackson III — better known as 50 Cent — and Horizon International Group, allowed participants to build their own small businesses from the ground up. This year's cohort featured a variety of businesses, from a Caribbean hot dog food truck to a financial literacy course on personal finance.

In its second year, the program encouraged innovation and taught business acumen to entrepreneurial-minded high school students, culminating in an opportunity to create their dream companies. During this 28 week entrepreneurial internship program, around 150 students from Madison, Worthing, Yates, Kashmere, Booker T. Washington, and Wheatley high schools learned how to transform an idea they were passionate about into a full fledged product they can pitch to investors.

The after-school program consists of three stages – the first 20 weeks are about getting familiar with business concepts and building connections with peers and teacher volunteers. The next eight weeks are spent in the incubation phase as students are split up into teams and local entrepreneurs lead lessons, helping them workshop their ideas into a fleshed out corporation, before finally the teams compete in Hustle Tank, where students pitch their ideas to a panel of celebrity and entrepreneurial judges. At the event in May, the panel included 50 Cent and Mattress Mack. The five winning teams are now eligible to split $500,000 in seed money for their companies.

Summer Reeves, VP of design of Umbridge, is in charge of managing the incubation phase and said she has noticed a significant shift in the ideas the student groups have come up with between the two cohorts of the program; the first year saw flashier tech pitches. But during the second year of the program, Reeves said the students sought to address issues they see in their day-to-day lives, including a group who worked to develop support services to aid formerly incarcerated individuals after they are released.

“This year, a lot of students were more on the practical side,” Reeves tells InnovationMap. “We actually had three teams that were focused on mental health apps which I think is a great example of what youth today are really focused on.”

Reeves started off as a mentor to four teams during the incubation phase of the program last year providing students with guidance on how to set up their business plans, create prototypes, and pitch their companies to investors. After three of her teams won the Hustle Tank competition previously, she took over planning the incubation phase and recruiting other local entrepreneurs to act as mentors.

“We give them recommendations on how to pitch and how to frame their pitch but they also have the ability to get creative so we had some students who did short skits — some that did raps and spoken word type things — lots of creativity,” Reeves says.

Patrice Allen, senior manager of G-Unity Business Labs, said they use the students’ individual strengths and creative thought processes to place them into their teams, including asking them in interviews at the beginning of the year to try to sell her a pen to understand their pitching process.

“That’s the question the students always remember,” Allen says. “‘Sell us this pen or pick something out and sell it to us.’ It’s the weirdest thing and they love it.”

In building the teams at each school, Allen worked with educators to make sure every team had students with a variety of communication and planning skills as well as financial awareness. But Allen felt students were most successful when they incorporated their personal interests into their product design. The first place team of Hustle Tank, Caribbean Hot Dog Boyz, was especially emblematic of this mindset as they combined one member's background of selling hotdogs with another’s Caribbean heritage to create a food truck that sells the unexpected combo of oxtail hotdogs.

The first place team of Hustle Tank 2023 was Caribbean Hot Dog Boyz. Photo via @gunitybusinesslab/Instagram

“To actually taste the food that they prepared was phenomenal,” Allen says “I have never ever thought that oxtails on a hotdog would be good but everybody was floored.”

Elizabeth Martin, director of communications and marketing for Horizon who runs the behind the scenes of funding, said students from the winning teams are now working on solidifying their business plans to qualify for the funds from the G-Unity foundation to develop their companies. Martin also said 50 Cent will retain a relationship with these teams, acting with varying levels of involvement depending on his deal with the students as anything from a silent partner to an investor.

“They do not walk home with $500,000 in their back pocket,” Martin explains. “We are investing in (them) — not giving — it’s an investment.”

The future of this program is uncertain as the Texas Education Association’s takeover of HISD is still in its transition phase but Martin advised to keep a lookout for an ABC Nightline interview of 50 Cent discussing G-Unity Business Labs, which is expected to release soon.

"I’ve spent years donating my time and energy to communities in need. I started G-Unity to do the same—to give back to kids so they have it a little easier than I did," Jackson writes on the website. "Team building and entrepreneurship are skills I learned along the way, but they are so important to develop early. I look forward to G-Unity supporting programs that are doing the crucial work of teaching kids to excel at life.

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7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”