Houston is a top city for female entrepreneurs, according to a recent study. Getty Images

Houston's innovation ecosystem has been booming with news, and it's likely some might have fallen through the cracks.

For this roundup of short stories within Houston innovation, Houston is recognized for its female-friendly business community, Texas ranks as top for gig economy, the latest Chevron investment is in nuclear energy, and more.

Houston named among top cities for female entrepreneurs

Houston ranked No. 11 on a new study on top cities for female business owners. Via fundera.com

According to a new study from Fundera, Houston ranks among the top 15 cities for female entrepreneurs in the United States. The Bayou City came in at No. 11 based on data pulled from The American Community Survey from the U.S. Census Bureau as well as the Tax Foundation. Metrics included:

  • Percent of self-employed business owners who are women — 18 percent of total score.
  • Percent of women employed in their own business — 18 percent of total score.
  • Earnings gap between male and female business owners — 18 percent of total score.
  • Housing cost as a percent of earnings for female entrepreneurs — 18 percent of total score.
  • Percent of residents with bachelor's degree, denoting high-skilled workforce — 9 percent of total score.
  • Job growth — 9 percent of total score.
  • Tax rates — 9 percent of total score.

"One of the most diverse cities in the country, Houston is also good to its women entrepreneur population," the study reads. "Its biggest strength here, however, may be in its job growth numbers, which were likely impacted by 2020's coronavirus pandemic. It remains to be seen whether the city's strong economic numbers will continue in the years to come."

Lubbock, the only other Texas city to crack the top 15, came in at No. 13.

Galen Data and Zibrio team up with new partnership

A Houston company's balance tracking technology is tapping into another Houston company's cloud technology. Photo courtesy of Zibrio

Houston-based tech companies, Galen Data and Zibrio, have announced a new medical device partnership. Zibrio's SmartScale, which can measure and track physical balance to identify an person's chance of falling, will be able to leverage the Galen CloudTM in order to securely connect data from the device with a patient's physician to support remote patient care.

"Our partnership with Zibrio is a case study in helping an early stage medical device company focus on what they do best," says Galen Data CEO Chris DuPont in a news release. "Galen Data provided outside expertise that has saved Zibrio the needless cost and burden of designing a cloud solution from scratch."

According to the release, the CDC reports that 28 percent of individuals over 65 fall each year, and falls are the leading cause of accidental death in those over 65. Amid the pandemic, the Australian PT Association found an increase in fall right of up to 30 percent.

"With COVID-19 impacting activities of older adults, it was even more critical to find a cost-effective solution to better track, manage, and analyze balance data from our SmartScale," says Zibrio founder and CEO, Katharine Forth, in the release.

IGNITE Madness startup applications close Sept. 4

Ignite Healthcare Network, a health tech startup group that promotes and advances female entrepreneurs, is closing startup applications for its October 22 and 29 event, Ignite Madness. The competition mimics a March Madness-style bracket and will be judged by 10 judges.

The brackets include:

  1. Mental /Behavioral Health
  2. Telemedicine/Remote Patient Monitoring
  3. Medical Devices
  4. Patient Engagement
  5. Employee Wellness
  6. Population Health/Analytics
  7. Femtech/Women's Health
  8. WILDCARD: Other Disruptive Solutions
Apply online for up to $300,000 in cash and prizes.

Texas named the 6th best state for freelance and gig workers

Gig workers are welcome in Texas. Screenshot via directlyapply.com

A job discovery platform, DirectlyApply, has identified the best gig economies to work in and Texas ranked as No. 6. The study looked at nine cost and job opportunity factors, which included the cost of living, the number of restaurants and attractions, the number of advertised gig roles, etc.

Texas has a reported 4,859 gig jobs and 16 gig companies operating locally, and the state sports an average gas price of $0.63 a liter and $1,422 a month to rent an apartment. New York, Florida, California, Ohio, and Illinois ranked ahead of Texas, respectively. The full study is available online.

Adapt2 Solutions recognized with award

Jason Kram is the executive vice president of Adapt2 Solutions. Photo courtesy of Adapt2 Solutions

Houston AI software company, Adapt2 Solutions, has been selected as the winner of the "Best AI Solution for Big Data" award in the 2020 AI Breakthrough Awards program conducted by AI Breakthrough. The awards recognize artificial intelligence and machine learning innovation. This year, the contest saw more than 2,750 nominations from over 15 different countries throughout the world, according to a news release.

"Energy enterprises are dealing with an increasingly complex and ever-changing landscape, including increased renewables, volatile markets, and increased pace of technology innovation for each of the commodity market," says James Johnson, managing director of AI Breakthrough, in the release.

"Adapt2 Solutions is in a unique position to support energy companies with powerful artificial intelligence technology to help their operations to automate, optimize and maintain a competitive advantage. We want to recognize this achievement by awarding them with 'Best AI Solution for Big Data' and we extend a hearty congratulations to the entire Adapt2 team on their well-deserved industry recognition."

The win comes at a strategic time for the company. Adapt2's predictive analytics models forecast unexpected fluctuations in power capacity. Amid the pandemic, this technology enables energy companies to map out demand at a time when they're balancing strained revenue and squeezed spending is paramount, Executive Vice President Jason Kram previously told InnovationMap.

"In times of disruption, big data can inform decision-making for energy companies to optimize energy-market operations with timely and reliable data," Kram says.

Houston Methodist introduces contactless temperature screening

Houston Methodist has set up over a hundred contactless temp checks across its facilities. Photo courtesy of Houston Methodist

Houston Methodist has incorporated new technology from care.ai, an AI-powered temperature monitoring platform, to conduct contactless temperature checks for visitors across 100 locations throughout eight hospitals and 36 physician clinics.

Upon entrance to designated areas, visitors stand in front of a tablet that scans an individual's temperature through the use of thermal technology aimed at the forehead. The technology aims to speed up screening measures and free up staff from the checkpoints. Should a visitor have an elevated skin temperature out of normal range, Methodist staff is contacted.

Chevron invests in nuclear fusion startup

The latest investment from CTV is in nuclear energy. Photo via chevron.com/technology/technology-ventures

Chevron's investment arm, Chevron Technology Ventures, recently announced an investment in Seattle-based Zap Energy Inc., which is working on a modular nuclear reactor. CTV sees nuclear energy as a promising avenue for innovation "across the globe access to affordable, reliable, and ever-cleaner energy," according to a news release.

"We see fusion technology as a promising low-carbon future energy source," says Barbara Burger, president of CTV, in a release. "Our Future Energy Fund investment in Zap Energy adds to Chevron's portfolio of companies we believe are likely to have a role in the energy transition."

This Series A investment is the 10th for Chevron's Future Energy Fund, which focuses on investments in companies that enable macro decarbonization, the mobility-energy nexus, and energy decentralization.

"Our Future Energy Fund investments provide us with strategic insight into power generation markets and potentially disruptive impacts of innovative approaches, like fusion, geothermal, wind, and solar, on the conventional power value chain," says Burger.

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Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

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This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.