From climatetech pitch days to the return of favorite festive shindigs, here's what not to miss this month. Photo via Getty Images

Editor's note: Houston’s innovation scene is loading up the calendar before the holidays. From climatetech pitch days to the return of favorite festive shindigs, here's what not to miss and how to register. Please note: this article may be updated to include additional event listings.

Dec. 3 — SouthWest-Midwest National Pediatric Device Innovation Consortium

This annual event brings together members, colleagues and guests of the FDA-supported pediatric consortium who are dedicated to assisting device innovators throughout the lifecycle in delivering innovative solutions to patients. Featured speakers include Dr. Danielle Gottlieb from Le Bonheur Children's Hospital, Balakrishna Haridas from Texas A&M University and Dr. Chester Koh from Texas Children’s Hospital.

This event is Wednesday, Dec. 3, from 3:30-8 p.m. at Texas A&M EnMed Tower. Register here.

Dec. 4 — Resiliency & Adaptation Sector Pitch Day: Scaling Solutions to Address Climate Disruption

Join innovators, industry leaders, investors and policymakers as they explore breakthrough climate and energy technologies at Greentown's latest installment of its Sector Pitch Day series, focused on resiliency and adaptation. Hear from Adrian Trömel, Chief Innovation Officer at Rice University; Eric Willman, Executive Director of the Rice WaTER Institute; pitches from 10 Greentown startups and more.

This event is Thursday, Dec. 4, from 1-3:30 p.m. at the Ion. The Ion Holiday Block Party follows. Register here.

Dec. 4 — The Ion District Holiday Block Party

The Ion District, Rice Alliance and Greentown Labs will celebrate the season during the Ion District Holiday Block Party. Expect to find local bites, drinks, music and meaningful connections across Houston’s innovation ecosystem. Guests are invited to participate in Operation Love’s holiday toy drive supporting local families.

This event is Thursday, Dec. 4, from 4-7 p.m. Register here.

Dec. 8 — Pumps & Pipes Annual Event 2025

The annual gathering brings together cross-industry leaders in aerospace, energy and medicine for engaging discussions and networking opportunities. Connor Grennan, Chief AI Architect at the NYU Stern School of Business, will present this year's keynote address, entitled "Practical Strategies to Increase Productivity." Other sessions will feature leaders from Cena Research Institute, NASA Ames Research Center, ExxonMobil, Southwest Airlines and more.

This event is Monday, Dec. 8, from 8 a.m.-5 p.m., at TMC Helix Park. Register here.

Dec. 9 — Jingle and Mingle

Don your ugliest sweater and snap a pic with Startup Santa! Bayou City Startups, Rocket Network, Founder Institute and Energytech Nexus are bringing back their popular Jingle Mingle for the third year. Network and celebrate with founders, community stakeholders and others in Houston's innovation scene. Donations to the Houston Food Bank are encouraged in place of tickets.

This event is Tuesday, Dec. 9, from 5-7 p.m., at the Solarium in Midtown. Register here.

Dec. 9 — European Innovation Spotlight

Celebrate European cooperation and innovation with the European Innovation Council during an exclusive demo night and networking event at Greentown Labs. Hear from 15 EIC-backed founders supported by the European Union with top-class climatetech technologies, listen to a fireside chat and engage in a networking event following the pitches.

This event is Tuesday, Dec. 9, from 4:30-7 p.m., at the Ion. Register here.

Dec. 9-10 — Energy LIVE

Energy LIVE is Reuters Events' flagship ConfEx that brings the full energy ecosystem together under one roof to solve the industry's most urgent commercial and operational challenges. The event will feature 3,000-plus senior executives across three strategic stages, a showcase of 75-plus exhibitors and six strategic content pillars.

This event is Dec. 9-10 at NRG Park. Register here.

Dec. 15 — Innov8 Hub Pitch Day

Hear pitches from members of the latest Innov8 Hub Innovators to Founders cohort, which empowers academic scientists and innovators to become successful startup founders. Meet and network with the founders over light bites and drinks at a reception following the pitch competition.

This event is Monday, Dec. 15, at the Innovation Center at UH Technology Bridge (Bldg. 4). Register here.

The Houston Founder Institute graduated its 2024 cohort this month, celebrating the class on May 21. The organization also opened applications for its next round. Photo via Getty Images

6 Houston startups graduate early-stage accelerator

ready to grow

The latest cohort of promising Houston startups has made it through the local program for the the world's largest pre-seed startup accelerator.

The Houston Founder Institute graduated its 2024 cohort this month, celebrating the class on May 21. The organization also opened applications for its next round.

"After meticulous selection process and intense four months of aggressive business-building sprints, constant evaluation, and feedback from investors and mentors, just 6 companies were able to make it through," the organization writes in a blog post. "Each of these Founders have demonstrated a high level of perseverance and creativity, and their businesses have been thoroughly vetted and supported by a panel of Houston's top startup experts and investors."

The newest alumni of the Houston program include:

  • Quickgredients, a company that's empowering diners with dietary needs and attract new customers for food businesses through targeted marketing and efficient management.
  • Truckersfinder, a platform connecting trucking companies to essential service providers to streamline their operations.
  • SEKCO, which is developing a technology to help laundry business operators offer a service to wash and press in five minutes or less by integrating wet vacuum cleaning and pressing in manual or automated stations.
  • Gym Rat, a hardware-software integration to improve and better track the fitness experience.
  • ReachAI is impowering small and medium-sized enterprises to elevate their digital footprint and online visibility through cutting-edge marketing strategies and comprehensive web presence optimization solutions.
  • STEMperts, a platform that's helping students learn better and improve grades by engaging them through a combination of interests and learning styles.

Houston Founder Institute is run by local directors James Phelan, Martín Martinez, Mery Ramirez, and Natasha Gorodetsky.

Following the completion of the program, the portfolio companies continue to have access to the Founder Institute's global network and post-graduate support programs to continue building their business.

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

Houston startup seeks to simplify sustainable fashion

design innovation

When the coronavirus pandemic started in 2020, people found themselves at home with a surplus of free time. Puzzles covered dining room tables, remnants of new hobbies were strewn across dens, TikTok dances were rehearsed, and television was binged. Maria Burgos found herself watching Netflix’s “Tidying Up with Marie Kondo,” which inspired her to clean out her closet. In practicing Kondo’s dogma of parting with items that don’t “spark joy,” Burgos uncovered a bigger issue to purge: America’s unsustainable fashion industry.

With piles of clothing ready for a new home, Burgos searched for reliable organizations to donate her possessions. Her research led her to learn more about the negative impact the fashion industry has on the environment.

According to Slate, almost 24 billion pounds of clothes and shoes are thrown out each year — more than double what we tossed two decades ago. Americans consume more than 20 billion garments each year, and each garment can be expected to be worn around seven times, according to The Wall Street Journal. We’re buying more clothing than ever when clothing is at its lowest cost.

A $17.99 linen crop top from H&M may seem like a steal, but the low price tag poses a much greater cost for the environment. Low-quality garments have a bleak chance of finding a secondhand home, and 80 percent of donated clothing won’t ever be seen see a charity shop rack. While some used clothing gets recycled as insulation, others end up in containers that overwhelm charities abroad or sit in landfills.

After donating her items to a local church, Burgos sought to be more sustainable and decided to try secondhand shopping.

“The good news was that I had so many options, new with tags, great conditions…the bad news was that it was so much that I ended up being frustrated because I didn't find what I liked,” she says. “I had to spend hours of my time scrolling thousands of items, dozens of filters, multiple platforms."

She asked herself why there wasn’t a website where she could find items in one place. “That was the genesis of Trendy Seconds,” she shares.

Maria Burgos founded Trendy Seconds to streamline second-hand shopping. Photo courtesy

Burgos has always been drawn to entrepreneurial aspirations. The Venezuela native started her first company, a film magazine, while in college. She studied dentistry and graduated with an offer to become a professor at her university, which she turned down to explore her passion for marketing further. After moving to Spain to obtain an MBA, she gained experience working for large corporations like 3M and GlaxoSmithKline.

Living in countries around the world and dipping her toes into different industries, Burgos gained a unique resume. When she came to the United States, she was eager to get her work permit. She obtained a real estate license and even began working at a startup before having her second child.

“I don't ever have the profile that is right to do what I'm doing at the moment, professionally. That has been something that I considered years ago as a disadvantage, [but] that has been my advantage because I come with a fresh pair of eyes,” she explains. “I solve problems differently, and I throw ideas out there that maybe other people don't,” she continues.

When she thought of Trendy Seconds, Burgos was trying to solve the issues she faced while striving to be a conscious consumer.

“I know that there are many other women like myself that are trying to make better choices, but right now, it's too hard,” she says.

She applied and graduated from the Founders Institute and won a Frost Bank grant to join Impact Hub Houston’s accelerator program.

“The accelerator opened up a lot of doors for me, and I went through all of them,” she shares.

Burgos launched Trendy Seconds, as an online marketplace where women can find pre-owned clothing or shop for new clothing from sustainable brands. The company shares items from more than 50 brands that can be searched by category, style, size, price, condition, and positive impact. To ensure the clothing is high quality, shoppers will find only gently-used or new items featured on Trendy Seconds.

Shoppers can have a much more cultivated experience on Trendy Seconds. Image courtesy

“We work with a fashion stylist to curate the product assortment because one thing that happens is analysis paralysis. When you have too many choices, you don't take action,” says Burgos.

Trendy Seconds creates wardrobe capsules that include an assortment of versatile styles that can be mixed and matched together. Visitors can search for various styles like beachwear, spring/summer, maternity, and special occasion attire.

Burgos has aligned with online secondhand marketplaces as well as sustainable clothing websites, where shoppers are redirected once they find items to purchase. She uses the United Nations’ sustainability goals to vet vendors and determine which brands to include on the website. Some featured eco-conscious brands include Christy Dawn, Eileen Fisher, Soul Flower, and Allbirds.

“Our ultimate goal is to make responsible consumption super easy,” Burgos explains.

Trendy Seconds is currently fundraising and Burgos is looking to bring in investors as she expands the company.

In the future, Burgos wants Trendy Seconds to evolve past the online marketplace and become a resource for circular fashion.

“How we envision this is that we will give the opportunity to consumers to come to the site and not just buy clothes, but actually purchase products and services that can help them increase the life of the clothes that they already have,” she shares.

“I believe that the best way to create a really good, like, motivated consumer audience is by letting them know how can they how can they help,” says Burgos.

Palo Alto-based Founder Institute is launching its Houston program at Station Houston. Image courtesy Founder Institute

Exclusive: Global early stage accelerator program launches second Texas location in Houston

New to town

Silicon Valley-based Founder Institute has announced its second Texas program in Houston, which will operate out of Station Houston. Founder Institute Houston applications for the inaugural cohort close May 19.

The early stage accelerator focuses on advancing startup companies in the pre-funding phase.

"It's quite different from any other program in Houston currently," says Neal Murthy, director of Founder Institute Houston. "It's an accelerator, but it's an idea-stage accelerator."

Before Founder Institute, Houston's only early stage opportunities were tied to universities — like the University of Houston's Red Labs or Rice University's Owl Spark — and those are typically focused on the university's community and on education, Murthy says.

In anticipation of launch, Founder Institute Houston will host a series of free entrepreneurial events, with the first one being March 19.

The Houston chapter will be ran by three directors: Murthy, a UH lecturer and angel investor, James Phelan, innovation expert with a real estate background, and Tabbie Saenz, Alice community leader and Baker Ripley mentor. Martin Martinez, managing director of Founder Institute Texas, who launched the Austin program, will also join the team.

"What's nice about our team is because we were already colleagues and friends prior to coming together on this project, we already have rapor, we can communicate, and we know each other's working styles, strengths, and weaknesses," says Phelan.

Founded in 2009 by Adeo Ressi and Jonathan Greechan, Founder Institute has chapters in 180 cities in 65 countries. They've contributed to 3,500 companies that have now raised over $800 million.

"Houston's supportive startup community and its affordable living costs have inspired a lot of entrepreneurial enthusiasm in the city. Every year, more co-working spaces and incubators move to Houston and it's now easier to launch a startup here than ever before. We aim to help that trend," Ressi says in a release. "I believe that our structured accelerator program will give potential founders the guidance they need to launch successful technology companies in Houston."

Every chapter focuses on the same idea-stage type of company and selects around 30 companies to participate in a 14-week course of education, mentorship, and business development. The cohort spends around three hours a week in educational programming, but then is expected to spend 20 to 25 hours a week working assignments and business development. It's designed to be tough. Usually, only around 10 founders of the 30 will cross the finish line.

"If they can't handle this course, then there's no way they're going to be a successful founder because this course is a breeze compared to running a company," says Phalen.

The Founder Institute alumni network is huge, and is one of the program's biggest perks. Not only do participants get access to a network successful founders, but they also usually have a foot in the door at the next stage of competitive accelerator programs.

"That's an enormously valuable thing from a fundraising aspect if you have the support from another successful founder standing next to you, vouching for you," Phelan says.

Another thing that makes Founder Institute different is, rather than operating off an equity approach, Founder Institute and its local directors receive warrants from each participating company. And, fellow founders and even program mentors receive a cut too.

"The sharing of that [means] everyone has economic incentives and it encourages collaboration among the cohort itself," Murthy says.

Founder Institute's expansion plan for Texas doesn't end at Austin and Houston. Two other locations in Dallas and San Antonio are also in route to the Lone Star State. However, Houston's a bit different of a city to be in, with it's diversity and large size.

"We are going to be targeting a very diverse community as well. We want to have everyone who hasn't had a chance to access resources like this," Saenz says.

Murthy, who has been a mentor for the Founder Institute in Austin, says it's so remarkable to see how much these founders accomplish in the 14 weeks, and he can't wait to see that affect the Houston ecosystem.

"We think that Houston needs a number of new elements to fill out its ecosystem, and this is one of them — an idea-stage accelerator," Murthy says. "We've seen the success it's had in Austin and globally, and we're hoping to bring that to Houston."

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Rice University researchers unveil new model that could sharpen MRI scans

MRI innovation

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI.

In a study recently published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Previous models only approximated how water molecules relaxed around contrasting agents. However, through this new model, known as the NMR eigenmodes framework, the research team has uncovered the “full physical equations” to explain the process.

“The concept is similar to how a musical chord consists of many notes,” Thiago Pinheiro, the study’s first author, a Rice doctoral graduate in chemical and biomolecular engineering and postdoctoral researcher in the chemical sciences division at Oak Ridge National Laboratory, said in a news release. “Previous models only captured one or two notes, while ours picks up the full harmony.”

According to Rice, the findings could lead to the development and application of new contrast agents for clearer MRIs in medicine and materials science. Beyond MRIs, the NMR relaxation method could also be applied to other areas like battery design and subsurface fluid flow.

“In the present paper, we developed a comprehensive theory to interpret those previous molecular dynamics simulations and experimental findings,” Dilipkumar Asthagiri, a senior computational biomedical scientist in the National Center for Computational Sciences at Oak Ridge National Laboratory, said in the release. ”The theory, however, is general and can be used to understand NMR relaxation in liquids broadly.”

The team has also made its code available as open source to encourage its adoption and further development by the broader scientific community.

“By better modeling the physics of nuclear magnetic resonance relaxation in liquids, we gain a tool that doesn’t just predict but also explains the phenomenon,” Walter Chapman, a professor of chemical and biomolecular engineering at Rice, added in the release. “That is crucial when lives and technologies depend on accurate scientific understanding.”

The study was backed by The Ken Kennedy Institute, Rice Creative Ventures Fund, Robert A. Welch Foundation and Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory.

Luxury transportation startup connects Houston with Austin and San Antonio

On The Road Again

Houston business and leisure travelers have a luxe new way to hop between Texas cities. Transportation startup Shutto has launched luxury van service connecting San Antonio, Austin, and Houston, offering travelers a comfortable alternative to flying or long-haul rideshare.

Bookings are now available Monday through Saturday with departure times in the morning and evening. One-way fares range from $47-$87, putting Shutto in a similar lane to Dallas-based Vonlane, which also offers routes from Houston to Austin and San Antonio.

Shutto enters the market at a time when highway congestion is a hotter topic than ever. With high-speed rail still years in the future, its model aims to provide fast, predictable service at commuter prices.

The startup touts an on-time departure guarantee and a relaxed, intimate ride. Only 12 passengers fit inside each Mercedes Sprinter van, equipped with Wi-Fi and leather seating. And each route includes a pit stop at roadside favorite Buc-ee's.

In announcing the launch, founder and CEO Alberto Salcedo called the company a new category in Texas mobility.

“We are bringing true disruptive mobility to Texas: faster and more convenient than flying (no security lines, no delays), more comfortable and exclusive than the bus or train, and up to 70 percent cheaper than private transfers or Uber Black,” Salcedo said in a release.

“Whether you’re commuting for business, visiting family, exploring Texas wineries, or doing a taco tour in San Antonio, Shutto makes traveling between these cities as easy and affordable as riding inside the city."

Beyond the scheduled routes, Shutto offers private, customizable trips anywhere in the country, a service it expects will appeal to corporate retreat planners, party planners, and tourists alike.

In Houston, the service picks up and drops off near the Galleria at the Foam Coffee & Kitchen parking lot, 5819 Richmond Ave.. In San Antonio, it is located at La Panadería Bakery’s parking lot at 8305 Broadway. In Austin, the location is the Pershing East Café parking lot at 2501 E. Fifth St.

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This article originally appeared on CultureMap.com.

Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”