The Houston Founder Institute graduated its 2024 cohort this month, celebrating the class on May 21. The organization also opened applications for its next round. Photo via Getty Images

The latest cohort of promising Houston startups has made it through the local program for the the world's largest pre-seed startup accelerator.

The Houston Founder Institute graduated its 2024 cohort this month, celebrating the class on May 21. The organization also opened applications for its next round.

"After meticulous selection process and intense four months of aggressive business-building sprints, constant evaluation, and feedback from investors and mentors, just 6 companies were able to make it through," the organization writes in a blog post. "Each of these Founders have demonstrated a high level of perseverance and creativity, and their businesses have been thoroughly vetted and supported by a panel of Houston's top startup experts and investors."

The newest alumni of the Houston program include:

  • Quickgredients, a company that's empowering diners with dietary needs and attract new customers for food businesses through targeted marketing and efficient management.
  • Truckersfinder, a platform connecting trucking companies to essential service providers to streamline their operations.
  • SEKCO, which is developing a technology to help laundry business operators offer a service to wash and press in five minutes or less by integrating wet vacuum cleaning and pressing in manual or automated stations.
  • Gym Rat, a hardware-software integration to improve and better track the fitness experience.
  • ReachAI is impowering small and medium-sized enterprises to elevate their digital footprint and online visibility through cutting-edge marketing strategies and comprehensive web presence optimization solutions.
  • STEMperts, a platform that's helping students learn better and improve grades by engaging them through a combination of interests and learning styles.

Houston Founder Institute is run by local directors James Phelan, Martín Martinez, Mery Ramirez, and Natasha Gorodetsky.

Following the completion of the program, the portfolio companies continue to have access to the Founder Institute's global network and post-graduate support programs to continue building their business.

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

Houston startup seeks to simplify sustainable fashion

design innovation

When the coronavirus pandemic started in 2020, people found themselves at home with a surplus of free time. Puzzles covered dining room tables, remnants of new hobbies were strewn across dens, TikTok dances were rehearsed, and television was binged. Maria Burgos found herself watching Netflix’s “Tidying Up with Marie Kondo,” which inspired her to clean out her closet. In practicing Kondo’s dogma of parting with items that don’t “spark joy,” Burgos uncovered a bigger issue to purge: America’s unsustainable fashion industry.

With piles of clothing ready for a new home, Burgos searched for reliable organizations to donate her possessions. Her research led her to learn more about the negative impact the fashion industry has on the environment.

According to Slate, almost 24 billion pounds of clothes and shoes are thrown out each year — more than double what we tossed two decades ago. Americans consume more than 20 billion garments each year, and each garment can be expected to be worn around seven times, according to The Wall Street Journal. We’re buying more clothing than ever when clothing is at its lowest cost.

A $17.99 linen crop top from H&M may seem like a steal, but the low price tag poses a much greater cost for the environment. Low-quality garments have a bleak chance of finding a secondhand home, and 80 percent of donated clothing won’t ever be seen see a charity shop rack. While some used clothing gets recycled as insulation, others end up in containers that overwhelm charities abroad or sit in landfills.

After donating her items to a local church, Burgos sought to be more sustainable and decided to try secondhand shopping.

“The good news was that I had so many options, new with tags, great conditions…the bad news was that it was so much that I ended up being frustrated because I didn't find what I liked,” she says. “I had to spend hours of my time scrolling thousands of items, dozens of filters, multiple platforms."

She asked herself why there wasn’t a website where she could find items in one place. “That was the genesis of Trendy Seconds,” she shares.

Maria Burgos founded Trendy Seconds to streamline second-hand shopping. Photo courtesy

Burgos has always been drawn to entrepreneurial aspirations. The Venezuela native started her first company, a film magazine, while in college. She studied dentistry and graduated with an offer to become a professor at her university, which she turned down to explore her passion for marketing further. After moving to Spain to obtain an MBA, she gained experience working for large corporations like 3M and GlaxoSmithKline.

Living in countries around the world and dipping her toes into different industries, Burgos gained a unique resume. When she came to the United States, she was eager to get her work permit. She obtained a real estate license and even began working at a startup before having her second child.

“I don't ever have the profile that is right to do what I'm doing at the moment, professionally. That has been something that I considered years ago as a disadvantage, [but] that has been my advantage because I come with a fresh pair of eyes,” she explains. “I solve problems differently, and I throw ideas out there that maybe other people don't,” she continues.

When she thought of Trendy Seconds, Burgos was trying to solve the issues she faced while striving to be a conscious consumer.

“I know that there are many other women like myself that are trying to make better choices, but right now, it's too hard,” she says.

She applied and graduated from the Founders Institute and won a Frost Bank grant to join Impact Hub Houston’s accelerator program.

“The accelerator opened up a lot of doors for me, and I went through all of them,” she shares.

Burgos launched Trendy Seconds, as an online marketplace where women can find pre-owned clothing or shop for new clothing from sustainable brands. The company shares items from more than 50 brands that can be searched by category, style, size, price, condition, and positive impact. To ensure the clothing is high quality, shoppers will find only gently-used or new items featured on Trendy Seconds.

Shoppers can have a much more cultivated experience on Trendy Seconds. Image courtesy

“We work with a fashion stylist to curate the product assortment because one thing that happens is analysis paralysis. When you have too many choices, you don't take action,” says Burgos.

Trendy Seconds creates wardrobe capsules that include an assortment of versatile styles that can be mixed and matched together. Visitors can search for various styles like beachwear, spring/summer, maternity, and special occasion attire.

Burgos has aligned with online secondhand marketplaces as well as sustainable clothing websites, where shoppers are redirected once they find items to purchase. She uses the United Nations’ sustainability goals to vet vendors and determine which brands to include on the website. Some featured eco-conscious brands include Christy Dawn, Eileen Fisher, Soul Flower, and Allbirds.

“Our ultimate goal is to make responsible consumption super easy,” Burgos explains.

Trendy Seconds is currently fundraising and Burgos is looking to bring in investors as she expands the company.

In the future, Burgos wants Trendy Seconds to evolve past the online marketplace and become a resource for circular fashion.

“How we envision this is that we will give the opportunity to consumers to come to the site and not just buy clothes, but actually purchase products and services that can help them increase the life of the clothes that they already have,” she shares.

“I believe that the best way to create a really good, like, motivated consumer audience is by letting them know how can they how can they help,” says Burgos.

Palo Alto-based Founder Institute is launching its Houston program at Station Houston. Image courtesy Founder Institute

Exclusive: Global early stage accelerator program launches second Texas location in Houston

New to town

Silicon Valley-based Founder Institute has announced its second Texas program in Houston, which will operate out of Station Houston. Founder Institute Houston applications for the inaugural cohort close May 19.

The early stage accelerator focuses on advancing startup companies in the pre-funding phase.

"It's quite different from any other program in Houston currently," says Neal Murthy, director of Founder Institute Houston. "It's an accelerator, but it's an idea-stage accelerator."

Before Founder Institute, Houston's only early stage opportunities were tied to universities — like the University of Houston's Red Labs or Rice University's Owl Spark — and those are typically focused on the university's community and on education, Murthy says.

In anticipation of launch, Founder Institute Houston will host a series of free entrepreneurial events, with the first one being March 19.

The Houston chapter will be ran by three directors: Murthy, a UH lecturer and angel investor, James Phelan, innovation expert with a real estate background, and Tabbie Saenz, Alice community leader and Baker Ripley mentor. Martin Martinez, managing director of Founder Institute Texas, who launched the Austin program, will also join the team.

"What's nice about our team is because we were already colleagues and friends prior to coming together on this project, we already have rapor, we can communicate, and we know each other's working styles, strengths, and weaknesses," says Phelan.

Founded in 2009 by Adeo Ressi and Jonathan Greechan, Founder Institute has chapters in 180 cities in 65 countries. They've contributed to 3,500 companies that have now raised over $800 million.

"Houston's supportive startup community and its affordable living costs have inspired a lot of entrepreneurial enthusiasm in the city. Every year, more co-working spaces and incubators move to Houston and it's now easier to launch a startup here than ever before. We aim to help that trend," Ressi says in a release. "I believe that our structured accelerator program will give potential founders the guidance they need to launch successful technology companies in Houston."

Every chapter focuses on the same idea-stage type of company and selects around 30 companies to participate in a 14-week course of education, mentorship, and business development. The cohort spends around three hours a week in educational programming, but then is expected to spend 20 to 25 hours a week working assignments and business development. It's designed to be tough. Usually, only around 10 founders of the 30 will cross the finish line.

"If they can't handle this course, then there's no way they're going to be a successful founder because this course is a breeze compared to running a company," says Phalen.

The Founder Institute alumni network is huge, and is one of the program's biggest perks. Not only do participants get access to a network successful founders, but they also usually have a foot in the door at the next stage of competitive accelerator programs.

"That's an enormously valuable thing from a fundraising aspect if you have the support from another successful founder standing next to you, vouching for you," Phelan says.

Another thing that makes Founder Institute different is, rather than operating off an equity approach, Founder Institute and its local directors receive warrants from each participating company. And, fellow founders and even program mentors receive a cut too.

"The sharing of that [means] everyone has economic incentives and it encourages collaboration among the cohort itself," Murthy says.

Founder Institute's expansion plan for Texas doesn't end at Austin and Houston. Two other locations in Dallas and San Antonio are also in route to the Lone Star State. However, Houston's a bit different of a city to be in, with it's diversity and large size.

"We are going to be targeting a very diverse community as well. We want to have everyone who hasn't had a chance to access resources like this," Saenz says.

Murthy, who has been a mentor for the Founder Institute in Austin, says it's so remarkable to see how much these founders accomplish in the 14 weeks, and he can't wait to see that affect the Houston ecosystem.

"We think that Houston needs a number of new elements to fill out its ecosystem, and this is one of them — an idea-stage accelerator," Murthy says. "We've seen the success it's had in Austin and globally, and we're hoping to bring that to Houston."

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UH student earns prestigious award for cancer vaccine research

up-and-comer

Cole Woody, a biology major in the College of Natural Sciences and Mathematics at the University of Houston, has been awarded a Barry Goldwater Scholarship, becoming the first sophomore in UH history to earn the prestigious prize for research in natural sciences, mathematics and engineering.

Woody was recognized for his research on developing potential cancer vaccines through chimeric RNAs. The work specifically investigates how a vaccine can more aggressively target cancers.

Woody developed the MHCole Pipeline, a bioinformatic tool that predicts peptide-HLA binding affinities with nearly 100 percent improvement in data processing efficiency. The MHCole Pipeline aims to find cancer-specific targets and develop personalized vaccines. Woody is also a junior research associate at the UH Sequencing Core and works in Dr. Steven Hsesheng Lin’s lab at MD Anderson Cancer Center.

“Cole’s work ethic and dedication are unmatched,” Preethi Gunaratne, director of the UH Sequencing Core and professor of Biology & Biochemistry at NSM, said in a news release. “He consistently worked 60 to 70 hours a week, committing himself to learning new techniques and coding the MHCole pipeline.”

Woody plans to earn his MD-PhD and has been accepted into the Harvard/MIT MD-PhD Early Access to Research Training (HEART) program. According to UH, recipients of the Goldwater Scholarship often go on to win various nationally prestigious awards.

"Cole’s ability to independently design and implement such a transformative tool at such an early stage in his career demonstrates his exceptional technical acumen and creative problem-solving skills, which should go a long way towards a promising career in immuno-oncology,” Gunaratne added in the release.

Houston founder on shaping the future of medicine through biotechnology and resilience

Guest Column

Living with chronic disease has shaped my life in profound ways. My journey began in 5th grade when I was diagnosed with Scheuermann’s disease, a degenerative disc condition that kept me sidelined for an entire year. Later, I was diagnosed with hereditary neuropathy with liability to pressure palsies (HNPP), a condition that significantly impacts nerve recovery. These experiences didn’t just challenge me physically, they reshaped my perspective on healthcare — and ultimately set me on my path to entrepreneurship. What started as personal health struggles evolved into a mission to transform patient care through innovative biotechnology.

A defining part of living with these conditions was the diagnostic process. I underwent nerve tests that involved electrical shocks to my hands and arms — without anesthesia — to measure nerve activity. The pain was intense, and each test left me thinking: There has to be a better way. Even in those difficult moments, I found myself thinking about how to improve the tools and processes used in healthcare.

HNPP, in particular, has been a frustrating condition. For most people, sleeping on an arm might cause temporary numbness that disappears in an hour. For me, that same numbness can last six months. Even more debilitating is the loss of strength and fine motor skills. Living with this reality forced me to take an active role in understanding my health and seeking solutions, a mindset that would later shape my approach to leadership.

Growing up in Houston, I was surrounded by innovation. My grandfather, a pioneering urologist, was among the first to introduce kidney dialysis in the city in the 1950s. His dedication to advancing patient care initially inspired me to pursue medicine. Though my path eventually led me to healthcare administration and eventually biotech, his influence instilled in me a lifelong commitment to medicine and making a difference.

Houston’s thriving medical and entrepreneurial ecosystems played a critical role in my journey. The city’s culture of innovation and collaboration provided opportunities to explore solutions to unmet medical needs. When I transitioned from healthcare administration to founding biotech companies, I drew on the same resilience I had developed while managing my own health challenges.

My experience with chronic disease also shaped my leadership philosophy. Rather than accepting diagnoses passively, I took a proactive approach questioning assumptions, collaborating with experts, and seeking new solutions. These same principles now guide decision-making at FibroBiologics, where we are committed to developing groundbreaking therapies that go beyond symptom management to address the root causes of disease.

The resilience I built through my health struggles has been invaluable in navigating business challenges. While my early career in healthcare administration provided industry insights, launching and leading companies required the same determination I had relied on in my personal health journey.

I believe the future of healthcare lies in curative treatments, not just symptom management. Fibroblast cells hold the promise of engaging the body’s own healing processes — the most powerful cure for chronic diseases. Cell therapy represents both a scientific breakthrough and a significant business opportunity, one that has the potential to improve patient outcomes while reducing long-term healthcare costs.

Innovation in medicine isn’t just about technology; it’s about reimagining what’s possible. The future of healthcare is being written today. At FibroBiologics, our mission is driven by more than just financial success. We are focused on making a meaningful impact on patients’ lives, and this purpose-driven approach helps attract talent, engage stakeholders, and differentiate in the marketplace. Aligning business goals with patient needs isn’t just the right thing to do, it’s a powerful model for sustainable growth and lasting innovation in biotech.

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Pete O’Heeron is the CEO and founder of FibroBiologics, a Houston-based regenerative medicine company.


Houston researchers make headway on affordable, sustainable sodium-ion battery

Energy Solutions

A new study by researchers from Rice University’s Department of Materials Science and NanoEngineering, Baylor University and the Indian Institute of Science Education and Research Thiruvananthapuram has introduced a solution that could help develop more affordable and sustainable sodium-ion batteries.

The findings were recently published in the journal Advanced Functional Materials.

The team worked with tiny cone- and disc-shaped carbon materials from oil and gas industry byproducts with a pure graphitic structure. The forms allow for more efficient energy storage with larger sodium and potassium ions, which is a challenge for anodes in battery research. Sodium and potassium are more widely available and cheaper than lithium.

“For years, we’ve known that sodium and potassium are attractive alternatives to lithium,” Pulickel Ajayan, the Benjamin M. and Mary Greenwood Anderson Professor of Engineering at Rice, said in a news release. “But the challenge has always been finding carbon-based anode materials that can store these larger ions efficiently.”

Lithium-ion batteries traditionally rely on graphite as an anode material. However, traditional graphite structures cannot efficiently store sodium or potassium energy, since the atoms are too big and interactions become too complex to slide in and out of graphite’s layers. The cone and disc structures “offer curvature and spacing that welcome sodium and potassium ions without the need for chemical doping (the process of intentionally adding small amounts of specific atoms or molecules to change its properties) or other artificial modifications,” according to the study.

“This is one of the first clear demonstrations of sodium-ion intercalation in pure graphitic materials with such stability,” Atin Pramanik, first author of the study and a postdoctoral associate in Ajayan’s lab, said in the release. “It challenges the belief that pure graphite can’t work with sodium.”

In lab tests, the carbon cones and discs stored about 230 milliamp-hours of charge per gram (mAh/g) by using sodium ions. They still held 151 mAh/g even after 2,000 fast charging cycles. They also worked with potassium-ion batteries.

“We believe this discovery opens up a new design space for battery anodes,” Ajayan added in the release. “Instead of changing the chemistry, we’re changing the shape, and that’s proving to be just as interesting.”

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This story originally appeared on EnergyCapitalHTX.com.