From climatetech pitch days to the return of favorite festive shindigs, here's what not to miss this month. Photo via Getty Images

Editor's note: Houston’s innovation scene is loading up the calendar before the holidays. From climatetech pitch days to the return of favorite festive shindigs, here's what not to miss and how to register. Please note: this article may be updated to include additional event listings.

Dec. 3 — SouthWest-Midwest National Pediatric Device Innovation Consortium

This annual event brings together members, colleagues and guests of the FDA-supported pediatric consortium who are dedicated to assisting device innovators throughout the lifecycle in delivering innovative solutions to patients. Featured speakers include Dr. Danielle Gottlieb from Le Bonheur Children's Hospital, Balakrishna Haridas from Texas A&M University and Dr. Chester Koh from Texas Children’s Hospital.

This event is Wednesday, Dec. 3, from 3:30-8 p.m. at Texas A&M EnMed Tower. Register here.

Dec. 4 — Resiliency & Adaptation Sector Pitch Day: Scaling Solutions to Address Climate Disruption

Join innovators, industry leaders, investors and policymakers as they explore breakthrough climate and energy technologies at Greentown's latest installment of its Sector Pitch Day series, focused on resiliency and adaptation. Hear from Adrian Trömel, Chief Innovation Officer at Rice University; Eric Willman, Executive Director of the Rice WaTER Institute; pitches from 10 Greentown startups and more.

This event is Thursday, Dec. 4, from 1-3:30 p.m. at the Ion. The Ion Holiday Block Party follows. Register here.

Dec. 4 — The Ion District Holiday Block Party

The Ion District, Rice Alliance and Greentown Labs will celebrate the season during the Ion District Holiday Block Party. Expect to find local bites, drinks, music and meaningful connections across Houston’s innovation ecosystem. Guests are invited to participate in Operation Love’s holiday toy drive supporting local families.

This event is Thursday, Dec. 4, from 4-7 p.m. Register here.

Dec. 8 — Pumps & Pipes Annual Event 2025

The annual gathering brings together cross-industry leaders in aerospace, energy and medicine for engaging discussions and networking opportunities. Connor Grennan, Chief AI Architect at the NYU Stern School of Business, will present this year's keynote address, entitled "Practical Strategies to Increase Productivity." Other sessions will feature leaders from Cena Research Institute, NASA Ames Research Center, ExxonMobil, Southwest Airlines and more.

This event is Monday, Dec. 8, from 8 a.m.-5 p.m., at TMC Helix Park. Register here.

Dec. 9 — Jingle and Mingle

Don your ugliest sweater and snap a pic with Startup Santa! Bayou City Startups, Rocket Network, Founder Institute and Energytech Nexus are bringing back their popular Jingle Mingle for the third year. Network and celebrate with founders, community stakeholders and others in Houston's innovation scene. Donations to the Houston Food Bank are encouraged in place of tickets.

This event is Tuesday, Dec. 9, from 5-7 p.m., at the Solarium in Midtown. Register here.

Dec. 9 — European Innovation Spotlight

Celebrate European cooperation and innovation with the European Innovation Council during an exclusive demo night and networking event at Greentown Labs. Hear from 15 EIC-backed founders supported by the European Union with top-class climatetech technologies, listen to a fireside chat and engage in a networking event following the pitches.

This event is Tuesday, Dec. 9, from 4:30-7 p.m., at the Ion. Register here.

Dec. 9-10 — Energy LIVE

Energy LIVE is Reuters Events' flagship ConfEx that brings the full energy ecosystem together under one roof to solve the industry's most urgent commercial and operational challenges. The event will feature 3,000-plus senior executives across three strategic stages, a showcase of 75-plus exhibitors and six strategic content pillars.

This event is Dec. 9-10 at NRG Park. Register here.

Dec. 15 — Innov8 Hub Pitch Day

Hear pitches from members of the latest Innov8 Hub Innovators to Founders cohort, which empowers academic scientists and innovators to become successful startup founders. Meet and network with the founders over light bites and drinks at a reception following the pitch competition.

This event is Monday, Dec. 15, at the Innovation Center at UH Technology Bridge (Bldg. 4). Register here.

The Houston Founder Institute graduated its 2024 cohort this month, celebrating the class on May 21. The organization also opened applications for its next round. Photo via Getty Images

6 Houston startups graduate early-stage accelerator

ready to grow

The latest cohort of promising Houston startups has made it through the local program for the the world's largest pre-seed startup accelerator.

The Houston Founder Institute graduated its 2024 cohort this month, celebrating the class on May 21. The organization also opened applications for its next round.

"After meticulous selection process and intense four months of aggressive business-building sprints, constant evaluation, and feedback from investors and mentors, just 6 companies were able to make it through," the organization writes in a blog post. "Each of these Founders have demonstrated a high level of perseverance and creativity, and their businesses have been thoroughly vetted and supported by a panel of Houston's top startup experts and investors."

The newest alumni of the Houston program include:

  • Quickgredients, a company that's empowering diners with dietary needs and attract new customers for food businesses through targeted marketing and efficient management.
  • Truckersfinder, a platform connecting trucking companies to essential service providers to streamline their operations.
  • SEKCO, which is developing a technology to help laundry business operators offer a service to wash and press in five minutes or less by integrating wet vacuum cleaning and pressing in manual or automated stations.
  • Gym Rat, a hardware-software integration to improve and better track the fitness experience.
  • ReachAI is impowering small and medium-sized enterprises to elevate their digital footprint and online visibility through cutting-edge marketing strategies and comprehensive web presence optimization solutions.
  • STEMperts, a platform that's helping students learn better and improve grades by engaging them through a combination of interests and learning styles.

Houston Founder Institute is run by local directors James Phelan, Martín Martinez, Mery Ramirez, and Natasha Gorodetsky.

Following the completion of the program, the portfolio companies continue to have access to the Founder Institute's global network and post-graduate support programs to continue building their business.

A Houston innovator found second-hand shopping time consuming. So, she designed a better experience. Image courtesy of Trendy Seconds

Houston startup seeks to simplify sustainable fashion

design innovation

When the coronavirus pandemic started in 2020, people found themselves at home with a surplus of free time. Puzzles covered dining room tables, remnants of new hobbies were strewn across dens, TikTok dances were rehearsed, and television was binged. Maria Burgos found herself watching Netflix’s “Tidying Up with Marie Kondo,” which inspired her to clean out her closet. In practicing Kondo’s dogma of parting with items that don’t “spark joy,” Burgos uncovered a bigger issue to purge: America’s unsustainable fashion industry.

With piles of clothing ready for a new home, Burgos searched for reliable organizations to donate her possessions. Her research led her to learn more about the negative impact the fashion industry has on the environment.

According to Slate, almost 24 billion pounds of clothes and shoes are thrown out each year — more than double what we tossed two decades ago. Americans consume more than 20 billion garments each year, and each garment can be expected to be worn around seven times, according to The Wall Street Journal. We’re buying more clothing than ever when clothing is at its lowest cost.

A $17.99 linen crop top from H&M may seem like a steal, but the low price tag poses a much greater cost for the environment. Low-quality garments have a bleak chance of finding a secondhand home, and 80 percent of donated clothing won’t ever be seen see a charity shop rack. While some used clothing gets recycled as insulation, others end up in containers that overwhelm charities abroad or sit in landfills.

After donating her items to a local church, Burgos sought to be more sustainable and decided to try secondhand shopping.

“The good news was that I had so many options, new with tags, great conditions…the bad news was that it was so much that I ended up being frustrated because I didn't find what I liked,” she says. “I had to spend hours of my time scrolling thousands of items, dozens of filters, multiple platforms."

She asked herself why there wasn’t a website where she could find items in one place. “That was the genesis of Trendy Seconds,” she shares.

Maria Burgos founded Trendy Seconds to streamline second-hand shopping. Photo courtesy

Burgos has always been drawn to entrepreneurial aspirations. The Venezuela native started her first company, a film magazine, while in college. She studied dentistry and graduated with an offer to become a professor at her university, which she turned down to explore her passion for marketing further. After moving to Spain to obtain an MBA, she gained experience working for large corporations like 3M and GlaxoSmithKline.

Living in countries around the world and dipping her toes into different industries, Burgos gained a unique resume. When she came to the United States, she was eager to get her work permit. She obtained a real estate license and even began working at a startup before having her second child.

“I don't ever have the profile that is right to do what I'm doing at the moment, professionally. That has been something that I considered years ago as a disadvantage, [but] that has been my advantage because I come with a fresh pair of eyes,” she explains. “I solve problems differently, and I throw ideas out there that maybe other people don't,” she continues.

When she thought of Trendy Seconds, Burgos was trying to solve the issues she faced while striving to be a conscious consumer.

“I know that there are many other women like myself that are trying to make better choices, but right now, it's too hard,” she says.

She applied and graduated from the Founders Institute and won a Frost Bank grant to join Impact Hub Houston’s accelerator program.

“The accelerator opened up a lot of doors for me, and I went through all of them,” she shares.

Burgos launched Trendy Seconds, as an online marketplace where women can find pre-owned clothing or shop for new clothing from sustainable brands. The company shares items from more than 50 brands that can be searched by category, style, size, price, condition, and positive impact. To ensure the clothing is high quality, shoppers will find only gently-used or new items featured on Trendy Seconds.

Shoppers can have a much more cultivated experience on Trendy Seconds. Image courtesy

“We work with a fashion stylist to curate the product assortment because one thing that happens is analysis paralysis. When you have too many choices, you don't take action,” says Burgos.

Trendy Seconds creates wardrobe capsules that include an assortment of versatile styles that can be mixed and matched together. Visitors can search for various styles like beachwear, spring/summer, maternity, and special occasion attire.

Burgos has aligned with online secondhand marketplaces as well as sustainable clothing websites, where shoppers are redirected once they find items to purchase. She uses the United Nations’ sustainability goals to vet vendors and determine which brands to include on the website. Some featured eco-conscious brands include Christy Dawn, Eileen Fisher, Soul Flower, and Allbirds.

“Our ultimate goal is to make responsible consumption super easy,” Burgos explains.

Trendy Seconds is currently fundraising and Burgos is looking to bring in investors as she expands the company.

In the future, Burgos wants Trendy Seconds to evolve past the online marketplace and become a resource for circular fashion.

“How we envision this is that we will give the opportunity to consumers to come to the site and not just buy clothes, but actually purchase products and services that can help them increase the life of the clothes that they already have,” she shares.

“I believe that the best way to create a really good, like, motivated consumer audience is by letting them know how can they how can they help,” says Burgos.

Palo Alto-based Founder Institute is launching its Houston program at Station Houston. Image courtesy Founder Institute

Exclusive: Global early stage accelerator program launches second Texas location in Houston

New to town

Silicon Valley-based Founder Institute has announced its second Texas program in Houston, which will operate out of Station Houston. Founder Institute Houston applications for the inaugural cohort close May 19.

The early stage accelerator focuses on advancing startup companies in the pre-funding phase.

"It's quite different from any other program in Houston currently," says Neal Murthy, director of Founder Institute Houston. "It's an accelerator, but it's an idea-stage accelerator."

Before Founder Institute, Houston's only early stage opportunities were tied to universities — like the University of Houston's Red Labs or Rice University's Owl Spark — and those are typically focused on the university's community and on education, Murthy says.

In anticipation of launch, Founder Institute Houston will host a series of free entrepreneurial events, with the first one being March 19.

The Houston chapter will be ran by three directors: Murthy, a UH lecturer and angel investor, James Phelan, innovation expert with a real estate background, and Tabbie Saenz, Alice community leader and Baker Ripley mentor. Martin Martinez, managing director of Founder Institute Texas, who launched the Austin program, will also join the team.

"What's nice about our team is because we were already colleagues and friends prior to coming together on this project, we already have rapor, we can communicate, and we know each other's working styles, strengths, and weaknesses," says Phelan.

Founded in 2009 by Adeo Ressi and Jonathan Greechan, Founder Institute has chapters in 180 cities in 65 countries. They've contributed to 3,500 companies that have now raised over $800 million.

"Houston's supportive startup community and its affordable living costs have inspired a lot of entrepreneurial enthusiasm in the city. Every year, more co-working spaces and incubators move to Houston and it's now easier to launch a startup here than ever before. We aim to help that trend," Ressi says in a release. "I believe that our structured accelerator program will give potential founders the guidance they need to launch successful technology companies in Houston."

Every chapter focuses on the same idea-stage type of company and selects around 30 companies to participate in a 14-week course of education, mentorship, and business development. The cohort spends around three hours a week in educational programming, but then is expected to spend 20 to 25 hours a week working assignments and business development. It's designed to be tough. Usually, only around 10 founders of the 30 will cross the finish line.

"If they can't handle this course, then there's no way they're going to be a successful founder because this course is a breeze compared to running a company," says Phalen.

The Founder Institute alumni network is huge, and is one of the program's biggest perks. Not only do participants get access to a network successful founders, but they also usually have a foot in the door at the next stage of competitive accelerator programs.

"That's an enormously valuable thing from a fundraising aspect if you have the support from another successful founder standing next to you, vouching for you," Phelan says.

Another thing that makes Founder Institute different is, rather than operating off an equity approach, Founder Institute and its local directors receive warrants from each participating company. And, fellow founders and even program mentors receive a cut too.

"The sharing of that [means] everyone has economic incentives and it encourages collaboration among the cohort itself," Murthy says.

Founder Institute's expansion plan for Texas doesn't end at Austin and Houston. Two other locations in Dallas and San Antonio are also in route to the Lone Star State. However, Houston's a bit different of a city to be in, with it's diversity and large size.

"We are going to be targeting a very diverse community as well. We want to have everyone who hasn't had a chance to access resources like this," Saenz says.

Murthy, who has been a mentor for the Founder Institute in Austin, says it's so remarkable to see how much these founders accomplish in the 14 weeks, and he can't wait to see that affect the Houston ecosystem.

"We think that Houston needs a number of new elements to fill out its ecosystem, and this is one of them — an idea-stage accelerator," Murthy says. "We've seen the success it's had in Austin and globally, and we're hoping to bring that to Houston."

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

---

This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

---

This conversation has been edited for brevity and clarity.