Three Houston women "are redefining what it means to build and run a business amid the new normal.” Photos courtesy

A spotlight is shining on three future Elon Musks from the Houston area.

Forbes magazine recently unveiled its final installment of 250 entrepreneurs on the Forbes Next 1000, a list of inspiring entrepreneurs and small-business leaders “who are redefining what it means to build and run a business amid the new normal.” Among the 250 are three entrepreneurs from the Houston area.

“As we enter another pandemic year, entrepreneurs and small-business owners are finding new ways to thrive amidst ever-uncertain circumstances,” Maneet Ahuja, senior editor of Forbes, says in a news release. “The fourth and final class of Next 1000 entrepreneurial heroes is writing the playbook for not only achieving financial recovery but speeding past it. These sole proprietors, self-funded shops, and pre-revenue startups are proving that — through resolve, hard work, and solid planning — anything is possible.”

Here are the three Houston-area entrepreneurs who made the final installment of the Next 1000 list for 2021, per Forbes:

Vernee Hines, 28, co-founder, UpBrainery Technologies (Houston)
UpBrainery Technologies is a technology ecosystem that's aimed at disrupting educational and classroom norms through the use of its proprietary technology. Its marketplace provides an AI-driven software platform and research-based, results-driven curriculum to students, parents, teachers and organizations. Cofounded in 2020 by Hines and Ghazal Qureshi, UpBrainery has helped more than 5,000 students. Clients include Whataburger, Nasdaq, The Houston Rockets, The Girl Scouts of America, and Girls Inc.

Carolyn Rodz, 42, co-founder, Hello Alice (Houston)
A former investment banker with JP Morgan, Rodz channeled her funding experience into creating Hello Alice, an online platform that serves as a one-stop-shop for aspiring entrepreneurs, connecting them with funders, services and professional networks. She originally cofounded the Houston-based company with Elizabeth Gore in 2017 to serve as an accelerator for women-owned businesses. It's since grown to work with all clients, and has raised $8.5 million.

JoAnn Ajayi-Scott, 60, founder, Essence of a Lady (Missouri City)

Essence of a Lady started as a social club in 1989' Scott later reorganized it into a non-profit organization to match girls with mentors in the hope that those relationships would give them the help and support they need to graduate high school. To date, they have impacted the lives of more than 1,000 girls through the more than 400 women who have mentored them as chaperones, workshop presenters, sponsors and donors.

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This article originally ran on CultureMap.

Forbes has identified 1,000 entrepreneurs as rising stars in the business world. And three of them call Houston home. Photos via Forbes

3 Houston innovators make Forbes list of up-and-coming entrepreneurs

next big things

Three Houston entrepreneurs are basking in the national spotlight.

The trio — Vernee Hines, Carolyn Rodz, and Siddhartha Sachdeva — were just named to Forbes' Next 1000 list of the country's up-and-coming entrepreneurs. They're among the 250 standouts who make up the second installment of this year's Next 1000 class.

Forbes says the year-round Next 1000 initiative "showcases the ambitious sole proprietors, self-funded shops, and pre-revenue startups in every region of the country — all with under $10 million in revenue or funding and infinite drive and hustle."

Forbes accepts nominees for Next 1000, and then "top business minds and entrepreneurial superstars" pick those who make the final cut. Among those minds are LinkedIn co-founder Reid Hoffman; baseball legend Alex Rodriguez; Sheryl Sandberg, chief operating officer of Facebook; and Carla Harris, managing director of Morgan Stanley.

"Americans are launching new companies at a historic rate, aided by the accelerated shift in the way we live and work and an influx of technological tools that made it easier for anyone to start their own business from anywhere," Maneet Ahuja, senior editor of Forbes, says in a news release. "The latest class of Next 1000 entrepreneurial heroes offer hope for the future as we emerge from the pandemic on the path towards economic recovery."

Hines, Rodz, and Sachdeva are the initiative's three Houston representatives in the summer 2021 group.

Hines co-founded UpBrainery Technologies with Ghazal Qureshi in 2020. UpBrainery operates a tech ecosystem aimed at disrupting educational and classroom norms through the use of proprietary technology, according to Forbes.

UpBrainery's marketplace provides an AI-driven software platform and research-based, results-driven curriculum to students, parents, teachers, and organizations. So far, UpBrainery has helped more than 5,000 students. Clients include Whataburger, Nasdaq, the Houston Rockets, the Girl Scouts of America, and Girls Inc.

"Because I deeply understand curriculum and the theory of education, I understand the biases marginalized students face every day, and I co-founded UpBrainery with the goal of eliminating historical education biases, leveling the playing field for underrepresented students, and providing a technology solution that reaches even the most disconnected student," Hines says on her company's website.

Rodz co-founded Hello Alice with Elizabeth Gore in 2017 as an accelerator for women-owned businesses. Today, the Hello Alice online platform serves as a one-stop shop for all aspiring entrepreneurs, connecting them with funders, services, and professional networks, Forbes explains. To date, it has raised $8.5 million in funding.

"Hello Alice is what I wish I had when I started my first business 15 years ago," Rodz told the Golden Seeds website in 2020. "After a career in investment banking, I made a long, hard, expensive transition into entrepreneurship. It wasn't until I sold that company that I realized how much I learned."

"When I started a second business, I discovered networks and opportunities I didn't know about the first time, and doors opened up," she added. "With Hello Alice, our goal was to put all entrepreneurs on an equal footing, giving them the knowledge, opportunities, and connections they need to thrive from day one."

Sachdeva founded Innowatts in 2014. The company offers an AI-powered SaaS platform that helps electricity providers operate more efficiently and transition toward sustainable energy, Forbes says. Innowatts has raised nearly $27 million in funding.

"The COVID-19 crisis has brought challenges for the energy sector, but there will always be a need for accurate forecasting and real-time intelligence," Sachdeva says in a recent news release. "Innowatts has flourished by using its groundbreaking AI technologies to help customers build resilience and cope with the unprecedented shifts in power consumption caused by the pandemic."

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Baylor College of Medicine launches VC fund to invest in biotech startups

fresh funding

Houston’s Baylor College of Medicine just unveiled a new venture capital fund that backs early-stage biotech startups—and it’s already made its first investment.

BCM Legacy Fund I, funded by philanthropies, invested an undisclosed amount in Houston biotech startup Nemea Therapeutics. Nemea, a spinout of the Baylor College of Medicine and Germany’s Lead Discovery Center, is developing an oral drug to treat metastatic triple-negative breast cancer that no longer responds to currently available therapies.

This type of aggressive cancer spreads from the breast to other areas of the body, such as the bones, liver, lungs or brain. Roughly 38,000 to 57,000 Americans are diagnosed each year with metastatic triple-negative breast cancer. One study showed about half of patients survive past the one-year mark following diagnosis and about one-third survive two years.

“Baylor College of Medicine’s laboratories produce discoveries with the potential to change patients’ lives, and too many of them stall where academic funding ends and private investment has not yet begun,” Dr. Jakub Tolar, president, CEO and executive dean of the Baylor College of Medicine, said in a press release. “The BCM Legacy Fund fills that gap, giving our scientists a path to advance their discoveries to patients.”

The National Institutes of Health awards more than $36 billion per year for biomedical research in the U.S., Baylor said. But some biomedical discoveries “never leave the starting line because they don’t yet fit the economics of venture capital,” the college said.

“The forefront of a new model”

The BCM Legacy Fund aggregates philanthropic capital from private foundations and donor-advised funds. It then invests in startups so they can move beyond that starting line and into later-stage investment rounds. The Greater Houston Community Foundation is the fund’s philanthropic partner.

“It’s exciting to be on the forefront of a new model for philanthropic capital,” said Houston entrepreneur and investor Burton Hanson, managing partner of the fund.

“Not only do we hope to solve a real problem by advancing these therapies to the patients who need them most, but we also hope this model will inspire others in the city and beyond toward philanthropic creativity and a posture of ‘I sacrifice; we win.’”

The fund expects to invest in about 15 early-stage startups over a five-year span. Baylor declined to divulge the amount of money in the fund and the size of the investment in Nemea.

Nemea’s “world-class chemistry”

Hanson oversees the Baylor fund alongside Chicago investor Steve Lehmann, who led the University of Chicago’s Innovation Fund.

Lehmann said Nemea, the fund’s first portfolio company, “has world-class chemistry, Baylor biology, and patients with no good options. Our job is to fund the experiments that carry it to the next handoff, so that industry and later-stage investors can take it from there.”

Based at Houston’s massive Texas Medical Center, Nemea plans to start clinical trials next year in collaboration with Baylor’s Lester and Sue Smith Breast Center.

Nemea previously received $9 million from the Lead Discovery Center and a $1.6 million grant from Baylor. Last year, the startup said it was seeking $25 million to $30 million in seed and Series A funding.

Debra McCoy of Houston, a former managing director at BlackRock and former partner at Bain & Co., and Paul Thomas, co-founder and CEO of Spring-based benefits manager Luscinia Health, sit on the Baylor fund’s governing board. Dr. Paul Klotman, former president, CEO and executive dean of Baylor, is a senior strategic adviser.

How does the fund find investment targets?

The Baylor Legacy Fund relies on two tools to help unearth early-stage biotech startups:

  • High-resolution “innovation maps” of research institutions. These maps surface hidden clusters of innovation, identify rising-star researchers and tie pockets of “innovation supply” at Baylor to areas of “innovation demand” in biotech.
  • AI-enhanced due diligence. AI agents assist with due diligence of early-stage biotech startups. The fund says the platform “distills the frameworks we’ve developed over a decade of teaching and investing into a flexible … diligence environment.”

MD Anderson unveils $3.4B expansion with two new Houston cancer care facilities

major expansion

The cutting edge of cancer-fighting technology and science is getting even sharper after MD Anderson announced last week that it will open two new facilities in the Texas Medical Center within the next five years. Inspiration Tower and Prism will expand MD Anderson’s annual patient load in the TMC to 250,000 annually and will incorporate a variety of new techniques.

The $3.4 billion project will add 2 million square feet to MD Anderson's TMC footprint, bringing its total campus size to 22 million square feet by 2032. Located at the corner of Fannin Street and Holcombe Boulevard, the cancer center says the two new facilities will serve as its new "front door" to the TMC.

“Every detail of these buildings, from the technology to the treatment rooms, was designed around our patients who will receive their care in them and our employees who will work in them. The facilities will serve as a physical representation of hope for the patients and their families who will walk through the doors,” Dr. Jeffrey E. Lee, president ad interim of UT MD Anderson, said in a news release. “Inspiration Tower and Prism are the future of cancer care, and we are grateful for the longstanding support and guidance we’ve received from the UT System Board of Regents to bring these projects to life. These facilities are part of the most impactful capital expansion in UT MD Anderson’s history.”

Prism is especially exciting as it will represent fully half of the linear accelerator treatment in the TMC. Linear accelerator is a radiation treatment that uses magnetically charged fields to deliver targeted external radiation therapy, like shooting cancer with a rail gun. The treatment is safer and has fewer side effects than older radiation treatments.

In addition, Prism will contain 12 MRI machines, four CT scanners, two PET-CT units, 18 radiation vaults and seven radiation simulators. Patient comfort has also been put at a premium with multiple gardens and roof overlooks.

“Every patient we treat deserves an environment that reflects the excellence of the care they receive at UT MD Anderson,” Chris McKee, executive vice president and chief strategy officer at UT MD Anderson, added in the release. “Our new facilities will be innovative, agile, adaptable and beautiful, and they will allow us to care for more patients, more effectively – in an environment that enhances healing and well-being. We are building for our future and for every patient who will be counting on us.”

Prism is slated to open in 2030.

Inspiration Tower will have 25 floors of surgical, diagnostic, and treatment services. At 1.4 million square feet, it’s currently expected to be the largest cancer-specific treatment facility in the United States. The tower will be divided into units for specific types of cancer, making it easy to integrate the advancing research being done all over Houston.

Like Prism, Inspiration Tower is specifically designed to offer comfort and reassurance, with more garden space, terraces, and beautiful scenery to ease patient distress. It is expected to open in 2032.

Tesla will pull the plug on Cybertruck production at Texas factory in 2027

Tesla Talk

Tesla’s Cybertruck, the hulking, stainless-steel pickup that inspired devotion and derision with its science-fiction looks, will cease production next year.

CEO Elon Musk announced the model’s demise Friday, November 6, with a curt post on X, his social media site, simply noting production of the vehicle “will be winding down” around the middle of 2027 at its facility outside Austin, Texas. Musk said the move was to allow increased production of its Cybercab robotaxi.

For the Cybertruck, a pet project of Musk who insisted it was Tesla’s best product, it marks an unceremonious end to one of the auto industry’s most ballyhooed debuts.

“Few vehicles in history have generated as much attention,” said Armen Hareyan, whose Torque News site covers autos. “The Cybertruck became a cultural symbol – loved, mocked and impossible to ignore.”

The Cybertruck rolled onto the scene in a dramatic unveiling in 2019, when a Tesla designer hurled a metal ball at the vehicle to demonstrate its supposedly unbreakable glass, only to see it shatter. He repeated the stunt on another window of the truck only to shatter that one, too.

Even as some critics scoffed, Musk was steadfast.

“I just wanted to make a futuristic battle tank — something that looks like it could come out of ‘Blade Runner’ or ‘Aliens’ or something like that but was also highly functional,” he told Automotive News. He called it “a better sports car than a Porsche 911” and “a better truck than an F-150.”

It struck some as the perfect vehicular reflection of the brash, convention-busting Musk.

“A really controversial vehicle unveiled by a controversial individual into a market where none of the electric trucks have been able to really capture demand,” said Spencer Penn, a former Tesla executive who left the company before the Cybertruck’s launch and now heads software developer LightSource.

Penn remembered watching the unveiling and feeling initially revolted by the sight of the Cybertruck, calling its appearance “madness.” But the more he looked at it, the more his opinion changed. He signed up for a pre-sale reservation, though ended up not getting a Cybertruck when Musk’s promises of a price tag under $40,000 went unmet and the first trucks sold for double or more. Penn called the Cybertruck part of Tesla’s adventurous spirit that drives innovation.

“Some of these bets work and some of these bets don’t,” he said.

While the decision to end Cybertruck production may be driven by sales realities, it's also a reflection of Tesla’s shift to autonomous vehicles, on which Musk is betting the company’s future.

Musk once forecast he’d make 250,000 Cybertrucks a year. Kelley Blue Book estimated Tesla sold just 20,237 of the vehicles last year, down about half from the year prior. Sales through the end of September this year were down another 28%, according to Kelley Blue Book.

If the imposing, sharp-angled, dystopian appearance of the Cybertruck weren’t enough to turn many potential buyers away, Musk did so himself by allying with a panoply of right-wing figures, most notably U.S. President Donald Trump. He alienated some customers as his image morphed from eccentric innovator to polarizing force trading his billions for political influence.

Once-passionate Tesla drivers rushed to sell off their cars, or slapped stickers on the bumper declaring, “I bought this before Elon went crazy.” Organizers staged demonstrations outside Tesla showrooms and urged investors to dump shares of the company’s stock. Anger spilled into violence, with Molotov cocktails hurled at Tesla vehicles, charging stations set ablaze, and dealerships covered in graffiti.

Lovers of the Cybertruck became targets, too, subjected to shouts of “Nazi!” and extended middle fingers.

Ross Blankenship is one of them. When he first laid eyes on the Cybertruck, he felt transported to a world from his childhood, when he would play “Halo,” the sci-fi video game. He had to have it.

“I had that sort of child in me wanting to be part of something cool that would change the future of automotive,” Blankenship said in a call from his Cybertruck as he drove through Sunnyside, Colorado. Even as Blankenship found he agreed with Musk on politics, he hated seeing a vehicle he loved turned into a political symbol. “I never bought it for any other reason than the fascination with the future technology of trucks … so that was a little heartbreaking.”

He would buy another Cybertruck again in a heartbeat, calling its end “a sad moment.”