Three Houston women "are redefining what it means to build and run a business amid the new normal.” Photos courtesy

A spotlight is shining on three future Elon Musks from the Houston area.

Forbes magazine recently unveiled its final installment of 250 entrepreneurs on the Forbes Next 1000, a list of inspiring entrepreneurs and small-business leaders “who are redefining what it means to build and run a business amid the new normal.” Among the 250 are three entrepreneurs from the Houston area.

“As we enter another pandemic year, entrepreneurs and small-business owners are finding new ways to thrive amidst ever-uncertain circumstances,” Maneet Ahuja, senior editor of Forbes, says in a news release. “The fourth and final class of Next 1000 entrepreneurial heroes is writing the playbook for not only achieving financial recovery but speeding past it. These sole proprietors, self-funded shops, and pre-revenue startups are proving that — through resolve, hard work, and solid planning — anything is possible.”

Here are the three Houston-area entrepreneurs who made the final installment of the Next 1000 list for 2021, per Forbes:

Vernee Hines, 28, co-founder, UpBrainery Technologies (Houston)
UpBrainery Technologies is a technology ecosystem that's aimed at disrupting educational and classroom norms through the use of its proprietary technology. Its marketplace provides an AI-driven software platform and research-based, results-driven curriculum to students, parents, teachers and organizations. Cofounded in 2020 by Hines and Ghazal Qureshi, UpBrainery has helped more than 5,000 students. Clients include Whataburger, Nasdaq, The Houston Rockets, The Girl Scouts of America, and Girls Inc.

Carolyn Rodz, 42, co-founder, Hello Alice (Houston)
A former investment banker with JP Morgan, Rodz channeled her funding experience into creating Hello Alice, an online platform that serves as a one-stop-shop for aspiring entrepreneurs, connecting them with funders, services and professional networks. She originally cofounded the Houston-based company with Elizabeth Gore in 2017 to serve as an accelerator for women-owned businesses. It's since grown to work with all clients, and has raised $8.5 million.

JoAnn Ajayi-Scott, 60, founder, Essence of a Lady (Missouri City)

Essence of a Lady started as a social club in 1989' Scott later reorganized it into a non-profit organization to match girls with mentors in the hope that those relationships would give them the help and support they need to graduate high school. To date, they have impacted the lives of more than 1,000 girls through the more than 400 women who have mentored them as chaperones, workshop presenters, sponsors and donors.

------

This article originally ran on CultureMap.

Forbes has identified 1,000 entrepreneurs as rising stars in the business world. And three of them call Houston home. Photos via Forbes

3 Houston innovators make Forbes list of up-and-coming entrepreneurs

next big things

Three Houston entrepreneurs are basking in the national spotlight.

The trio — Vernee Hines, Carolyn Rodz, and Siddhartha Sachdeva — were just named to Forbes' Next 1000 list of the country's up-and-coming entrepreneurs. They're among the 250 standouts who make up the second installment of this year's Next 1000 class.

Forbes says the year-round Next 1000 initiative "showcases the ambitious sole proprietors, self-funded shops, and pre-revenue startups in every region of the country — all with under $10 million in revenue or funding and infinite drive and hustle."

Forbes accepts nominees for Next 1000, and then "top business minds and entrepreneurial superstars" pick those who make the final cut. Among those minds are LinkedIn co-founder Reid Hoffman; baseball legend Alex Rodriguez; Sheryl Sandberg, chief operating officer of Facebook; and Carla Harris, managing director of Morgan Stanley.

"Americans are launching new companies at a historic rate, aided by the accelerated shift in the way we live and work and an influx of technological tools that made it easier for anyone to start their own business from anywhere," Maneet Ahuja, senior editor of Forbes, says in a news release. "The latest class of Next 1000 entrepreneurial heroes offer hope for the future as we emerge from the pandemic on the path towards economic recovery."

Hines, Rodz, and Sachdeva are the initiative's three Houston representatives in the summer 2021 group.

Hines co-founded UpBrainery Technologies with Ghazal Qureshi in 2020. UpBrainery operates a tech ecosystem aimed at disrupting educational and classroom norms through the use of proprietary technology, according to Forbes.

UpBrainery's marketplace provides an AI-driven software platform and research-based, results-driven curriculum to students, parents, teachers, and organizations. So far, UpBrainery has helped more than 5,000 students. Clients include Whataburger, Nasdaq, the Houston Rockets, the Girl Scouts of America, and Girls Inc.

"Because I deeply understand curriculum and the theory of education, I understand the biases marginalized students face every day, and I co-founded UpBrainery with the goal of eliminating historical education biases, leveling the playing field for underrepresented students, and providing a technology solution that reaches even the most disconnected student," Hines says on her company's website.

Rodz co-founded Hello Alice with Elizabeth Gore in 2017 as an accelerator for women-owned businesses. Today, the Hello Alice online platform serves as a one-stop shop for all aspiring entrepreneurs, connecting them with funders, services, and professional networks, Forbes explains. To date, it has raised $8.5 million in funding.

"Hello Alice is what I wish I had when I started my first business 15 years ago," Rodz told the Golden Seeds website in 2020. "After a career in investment banking, I made a long, hard, expensive transition into entrepreneurship. It wasn't until I sold that company that I realized how much I learned."

"When I started a second business, I discovered networks and opportunities I didn't know about the first time, and doors opened up," she added. "With Hello Alice, our goal was to put all entrepreneurs on an equal footing, giving them the knowledge, opportunities, and connections they need to thrive from day one."

Sachdeva founded Innowatts in 2014. The company offers an AI-powered SaaS platform that helps electricity providers operate more efficiently and transition toward sustainable energy, Forbes says. Innowatts has raised nearly $27 million in funding.

"The COVID-19 crisis has brought challenges for the energy sector, but there will always be a need for accurate forecasting and real-time intelligence," Sachdeva says in a recent news release. "Innowatts has flourished by using its groundbreaking AI technologies to help customers build resilience and cope with the unprecedented shifts in power consumption caused by the pandemic."

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

Texas space co. takes giant step toward lunar excavator deployment

Out of this world

Lunar exploration and development are currently hampered by the fact that the moon is largely devoid of necessary infrastructure, like spaceports. Such amenities need to be constructed remotely by autonomous vehicles, and making effective devices that can survive the harsh lunar surface long enough to complete construction projects is daunting.

Enter San Antonio-based Astroport Space Technologies. Founded in San Antonio in 2020, the company has become a major part of building plans beyond Earth, via its prototype excavator, and in early February, it completed an important field test of its new lunar excavator.

The new excavator is designed to function with California-based Astrolab's Flexible Logistics and Exploration (FLEX) rover, a highly modular vehicle that will perform a variety of functions on the surface of the moon.

In a recent demo, the Astroport prototype excavator successfully integrated with FLEX and proceeded to dig in a simulated lunar surface. The excavator collected an average of 207 lbs (94kg) of regolith (lunar surface dust) in just 3.5 minutes. It will need that speed to move the estimated 3,723 tons (3,378 tonnes) of regolith needed for a lunar spaceport.

After the successful test, both Astroport and Astrolab expressed confidence that the excavator was ready for deployment. "Leading with this successful excavator demo proves that our technology is no longer theoretical—it is operational," said Sam Ximenes, CEO of Astroport.

"This is the first of many implements in development that will turn Astrolab's FLEX rover into the 'Swiss Army Knife' of lunar construction. To meet the infrastructure needs of the emerging lunar economy, we must build the 'Port' before the 'Ship' arrives. By leveraging the FLEX platform, we are providing the Space Force, NASA, and commercial partners with a 'Shovel-Ready' construction capability to secure the lunar high ground."

"We are excited to provide the mobility backbone for Astroport's groundbreaking construction technology," said Jaret Matthews, CEO of Astrolab, in a release. "Astrolab is dedicated to establishing a viable lunar ecosystem. By combining our FLEX rover's versatility with Astroport's civil engineering expertise, we are delivering the essential capabilities required for a sustainable lunar economy."

---

This article originally appeared on CultureMap.com.

Houston biotech co. raises $11M to advance ALS drug development

drug money

Houston-based clinical-stage biotechnology company Coya Therapeutics (NASDAQ: COYA) has raised $11.1 million in a private investment round.

India-based pharmaceuticals company Dr. Reddy’s Laboratories Inc. led the round with a $10 million investment, according to a news release. New York-based investment firm Greenlight Capital, Coya’s largest institutional shareholder, contributed $1.1 million.

The funding was raised through a definitive securities purchase agreement for the purchase and sale of more than 2.5 million shares of Coya's common stock in a private placement at $4.40 per share.

Coya reports that it plans to use the proceeds to scale up manufacturing of low-dose interleukin-2 (IL-2), which is a component of its COYA 302 and will support the commercial readiness of the drug. COYA 302 enhances anti-inflammatory T cell function and suppresses harmful immune activity for treatment of Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia (FTD), Parkinson’s disease and Alzheimer’s disease.

The company received FDA acceptance for its investigational new drug application for COYA 302 for treating ALS and FTD this summer. Its ALSTARS Phase 2 clinical trial for ALS treatment launched this fall in the U.S. and Canada and has begun enrolling and dosing patients. Coya CEO Arun Swaminathan said in a letter to investors that the company also plans to advance its clinical programs for the drug for FTD therapy in 2026.

Coya was founded in 2021. The company merged with Nicoya Health Inc. in 2020 and raised $10 million in its series A the same year. It closed its IPO in January 2023 for more than $15 million. Its therapeutics uses innovative work from Houston Methodist's Dr. Stanley H. Appel.