next big things

3 Houston innovators make Forbes list of up-and-coming entrepreneurs

Forbes has identified 1,000 entrepreneurs as rising stars in the business world. And three of them call Houston home. Photos via Forbes

Three Houston entrepreneurs are basking in the national spotlight.

The trio — Vernee Hines, Carolyn Rodz, and Siddhartha Sachdeva — were just named to Forbes' Next 1000 list of the country's up-and-coming entrepreneurs. They're among the 250 standouts who make up the second installment of this year's Next 1000 class.

Forbes says the year-round Next 1000 initiative "showcases the ambitious sole proprietors, self-funded shops, and pre-revenue startups in every region of the country — all with under $10 million in revenue or funding and infinite drive and hustle."

Forbes accepts nominees for Next 1000, and then "top business minds and entrepreneurial superstars" pick those who make the final cut. Among those minds are LinkedIn co-founder Reid Hoffman; baseball legend Alex Rodriguez; Sheryl Sandberg, chief operating officer of Facebook; and Carla Harris, managing director of Morgan Stanley.

"Americans are launching new companies at a historic rate, aided by the accelerated shift in the way we live and work and an influx of technological tools that made it easier for anyone to start their own business from anywhere," Maneet Ahuja, senior editor of Forbes, says in a news release. "The latest class of Next 1000 entrepreneurial heroes offer hope for the future as we emerge from the pandemic on the path towards economic recovery."

Hines, Rodz, and Sachdeva are the initiative's three Houston representatives in the summer 2021 group.

Hines co-founded UpBrainery Technologies with Ghazal Qureshi in 2020. UpBrainery operates a tech ecosystem aimed at disrupting educational and classroom norms through the use of proprietary technology, according to Forbes.

UpBrainery's marketplace provides an AI-driven software platform and research-based, results-driven curriculum to students, parents, teachers, and organizations. So far, UpBrainery has helped more than 5,000 students. Clients include Whataburger, Nasdaq, the Houston Rockets, the Girl Scouts of America, and Girls Inc.

"Because I deeply understand curriculum and the theory of education, I understand the biases marginalized students face every day, and I co-founded UpBrainery with the goal of eliminating historical education biases, leveling the playing field for underrepresented students, and providing a technology solution that reaches even the most disconnected student," Hines says on her company's website.

Rodz co-founded Hello Alice with Elizabeth Gore in 2017 as an accelerator for women-owned businesses. Today, the Hello Alice online platform serves as a one-stop shop for all aspiring entrepreneurs, connecting them with funders, services, and professional networks, Forbes explains. To date, it has raised $8.5 million in funding.

"Hello Alice is what I wish I had when I started my first business 15 years ago," Rodz told the Golden Seeds website in 2020. "After a career in investment banking, I made a long, hard, expensive transition into entrepreneurship. It wasn't until I sold that company that I realized how much I learned."

"When I started a second business, I discovered networks and opportunities I didn't know about the first time, and doors opened up," she added. "With Hello Alice, our goal was to put all entrepreneurs on an equal footing, giving them the knowledge, opportunities, and connections they need to thrive from day one."

Sachdeva founded Innowatts in 2014. The company offers an AI-powered SaaS platform that helps electricity providers operate more efficiently and transition toward sustainable energy, Forbes says. Innowatts has raised nearly $27 million in funding.

"The COVID-19 crisis has brought challenges for the energy sector, but there will always be a need for accurate forecasting and real-time intelligence," Sachdeva says in a recent news release. "Innowatts has flourished by using its groundbreaking AI technologies to help customers build resilience and cope with the unprecedented shifts in power consumption caused by the pandemic."

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Building Houston

 
 

From a low-cost vaccine to an app that can help reduce exposure, here are the latest COVID-focused and Houston-based research projects. Photo via Getty Images

While it might seem like the COVID-19 pandemic has settled down for the time being, there's plenty of innovative research ongoing to create solutions for affordable vaccines and tech-enabled protection against the spread of the virus.

Some of that research is happening right here in Houston. Here are two innovative projects in the works at local institutions.

UH researcher designs app to monitor best times to shop

A UH professor is putting safe shopping at your fingertips. Photo via UH.edu

When is the best time to run an errand in the pandemic era we currently reside? There might be an app for that. Albert Cheng, professor of computer science and electrical and computer engineering at the University of Houston, is working on a real-time COVID-19 infection risk assessment and mitigation system. He presented his plans at the Institute of Electrical and Electronics Engineers conference HPC for Urgent Decision Making and will publish the work in IEEE Xplore.

Cheng's work analyzes up-to-date data from multiple open sources to see when is the best time to avoid crowds and accomplish activities outside the home.

"Preliminary work has been performed to determine the usability of a number of COVID-19 data websites and other websites such as grocery stores and restaurants' popular times and traffic," Cheng says in a UH release. "Other data, such as vaccination rates and cultural factors (for example, the percentage of people willing to wear facial coverings or masks in an area), are also used to determine the best grocery store to shop in within a time frame."

To use the app, a user would input their intended destinations and the farthest distance willing to go, as well as the time frame of the trip. The risk assessment and mitigation system, or RT-CIRAM, then "provides as output the target location and the time interval to reach there that would reduce the chance of infections," said Cheng.

There's a lot to it, says Cheng, and the process is highly reliant on technology.

"We are leveraging urgent high-performance cloud computing, coupled with time-critical scheduling and routing techniques, along with our expertise in real-time embedded systems and cyber-physical systems, machine learning, medical devices, real-time knowledge/rule-based decision systems, formal verification, functional reactive systems, virtualization and intrusion detection," says Cheng.

2 Houston hospitals team up with immunotherapy company for new vaccine for Africa

The new vaccine will hopefully help mitigate spread of the disease in Sub-Saharan Africa. Photo via bcm.edu

Baylor College of Medicine and Texas Children's Hospital have teamed up with ImmunityBio Inc. — a clinical-stage immunotherapy company — under a licensing agreement to develop a safe, effective and affordable COVID-19 vaccine.

BCM has licensed out a recombinant protein COVID-19 vaccine candidate that was developed at the Texas Children's Hospital Center for Vaccine Development to ImmunityBio. According to the release, the company engaged in license negotiations with the BCM Ventures team, about the vaccine that could address the current pandemic needs in South Africa.

"We hope that our COVID-19 vaccine for global health might become an important step towards advancing vaccine development capacity in South Africa, and ultimately for all of Sub-Saharan Africa," says Dr. Peter Hotez, professor and dean of the National School of Tropical Medicine at Baylor and co-director of the Texas Children's Hospital Center for Vaccine Development.

ImmunityBio, which was founded in 2014 by Dr. Patrick Soon-Shiong, is working on innovative immunotherapies that address serious unmet needs in infectious diseases, according to a news release from BCM.

"There is a great need for second-generation vaccines, which are accessible, durable and offer broad protection against the emerging variants," says Soon-Shiong. "ImmunityBio has executed on a heterologous ("mix-and-match") strategy to develop a universal COVID-19 vaccine. To accomplish this, we have embarked upon large-scale good manufacturing practices and development of DNA (adenovirus), RNA (self-amplifying mRNA) and subunit protein (yeast) vaccine platforms. This comprehensive approach will leverage our expertise in these platforms for both infectious disease and cancer therapies."

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