These three entrepreneurs are in the business of solving problems. Courtesy photos

Entrepreneurs see a problem, and solve it. This week's three innovators to know are no different. All three have personal stories of realizing there's something not right — and there's something they could do about it.

Here are this week's innovators with small businesses and big growth plans.

Yared Akalou, founder of Alcove Group

Courtesy of Yared Akalou

Yared Akalou found the perfect job for himself — only problem was that it was in San Diego. Uninterested in moving his wife and young daughter across the country, he decided to prove to his new employer that he could handle most of the job's responsibilities remotely, while traveling when needed.

It wasn't easy, and his user experience-focused mind realized there was a concentration problem when you worked remotely in public spaces. Now, with Alcove, he's created a solution. Alcove is a laptop case that pops up into a workspace that increases focus and privacy.

Alcove is available online, but Akalou has lofty goals of partnering with large companies to get Alcove in the hands of consultants, for instance.

Megan Eddings, founder of Accel Lifestyle

Courtesy of Accel Lifestyle

Entrepreneurs have to have a certain amount of positivity when it comes to all the challenges they face, and Megan Eddings has a surplus of both challenges and positivity. She's fought for years to design the perfect fabric that doesn't hold on to bacteria and sweat smells for a line of athleticwear she's creating. The chemist-turned-medical sales professional is now close to getting her company, Accel Lifestyle, off the ground.

When she's not focusing on Accel, she likes to inspire others to follow their passions and take a leap of faith like she did at speaking engagements or on social media. She even inspired her husband, Kyle, to start something of his own too.

Josh Feinberg, co-founder of Tenavox

Courtesy of Tenavox

For years, Josh Feinberg was a broker focusing on The Woodlands when he realized there was a huge need in the commercial real estate sector that brokers weren't able to fill. The equation was just off — there just aren't enough brokers to manage the millions of available square feet of space in major metros.

Feinberg created Tenavox with his business partner, Marissa Limsiaco, who is based in Austin. Tenavox is a website where small business owners can find space that fits their needs. Tenavox can benefits both sides of the transaction: entrepreneurs are only shown compatable properties and brokers are only getting tenant leads that are serious contenders.

The site also has VoxLink, which is a directory of industry experts — tenant brokers, moving companies, lawyers, etc. Feinberg hopes to expand to 50 metros in the next five years.

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Houston organizations identify promising life science cos. at annual event

startups to watch

For the 13th year, the Texas Life Science Forum hosted by BioHouston and the Rice Alliance for Technology and Entrepreneurship celebrated innovative companies from around the world that are creating new treatments and solutions to today's biggest health care challenges.

This week, over 40 companies presenting their innovations across cancer, cardiovascular disease, biotechnology, and more. Nearly 700 venture capitalists, corporate innovation groups, angel networks, industry leaders, academics, service providers, and others attended the event on November 7 at Rice's BioScience Research Collaborative in the Texas Medical Center.

Just like in previous years, the event ended with the announcement of the 10 companies that were deemed "most promising" based on their pitches and technologies. Of the 10 companies named, six are headquartered in Houston and an additional two startups on the list have a presence here.

The 2024 most-promising life science companies are:

Houston-based clinical-stage cell therapy company March Biosciencesis developing a pipeline of innovative therapies, beginning with targeting relapsed an refractory T cell lymphoma.

ImmunoGenesis, headquartered in Houston, is a clinical-stage biotechnology company developing a potent PD-1 pathway targeting agent specifically engineered for immuneexcluded tumors, which account for over 50 percent of all cancers

Taurus Vascular, based in Houston, is revolutionizing endovascular aneurysm repair by addressing the critical issues of residual aneurysm pressurization and endoleaks with its catheter-deployable aortocaval shunt.

Headquartered in Australia with a Houston presence, Foxo Technologyoffers HIPAA-compliant, communication software for anyone in health care.

Another Houston company,Voythoshas built an AI platform to better predict and diagnose cardiovascular disease earlier to enhance quality and cost of care.

Dutch company Loop Robot, which has a presence in Houston, automates disinfection with its intelligent robot to make medical-grade disinfection faster, safer, and digitally auditable.

London-based Case45develops and commercializes pan-cancer prognostic tests using unique integration of tumor evolution and AI and is beginning with breast and lung cancers.

OmniNano Pharmaceuticals, headquartered in Houston, has developed a nano-drug delivery platform technology enables simultaneous co-delivery of multiple therapeutic agents designed specifically to treat solid tumors.

Houston-based clinical-stage biopharmaceutical company Mongoose Bio is pioneering first-in-class T cell receptor T cell (TCR-T) therapies for cancer treatment.

Rua Diagnosticsfrom New York is redefining point-of-care diagnostics with advanced micro gas chromatography technology for breath analysis that's capable of detecting a wide range of prevalent and deadly diseases.

In addition to this list, the event named two additional awards. United Kingdom's Cytecom, which provides quick and accurate diagnosis and treatment of blood infections stems, was selected by the crowd as the People's Choice award winner.

Last, but not least, BioHouston's Ann Tanabe awarded this year's Michael E. Debakey Award to Houston-based Autoimmunity BioSolutions, seed-stage biotech developing a next-generation, immuno-corrective therapy for treatment of autoimmune diseases to restore normal immune function.

University of Houston taps global partner to work on hydrogen, sustainability breakthroughs

team work

The University of Houston and Scotland’s Heriot-Watt University have been awarded seed grants to six energy projects, which is part of an innovative transatlantic research collaboration.

Researchers from both universities will take on projects that will concentrate on innovations that range from advanced hydrogen sensing technology to converting waste into sustainable products.

This will mark the first round of awards under the “UH2HWU” seed grant program. The program was created following the signing of a memorandum of understanding between both institutions in 2024. The universities will “seek to drive global progress in energy research, education, and innovation, with a particular focus on hydrogen as a key element in the shift toward cleaner energy,” according to a news release.

“This partnership is rooted in a shared commitment to advancing research that supports a just energy transition,” Ramanan Krishnamoorti, vice president for energy and innovation at UH, says in a news release. “Hydrogen, and in particular low carbon hydrogen, is essential to achieving sustainable energy solutions.”

The UH2HWU program provided $20,000 in seed funding to each of the projects. The program will help with the goal of helping researchers secure additional funding from private sources, companies, and government with a total of 11 proposals being submitted, and a panel of industry experts reviewing them.

One of the winning projects was titled “A joint research project on the feasibility of Repurposing Offshore Infrastructure for Clean Energy in the North Sea aka ROICE North Sea,” and was led by Ram Seetharam, ROICE Program executive director at UH, Edward Owens, professor of energy, geoscience, infrastructure and society at HWU, and Sandy Kerr, associate professor of economics at HWU.

The UH ROICE team focused on reusing old offshore structures for clean energy instead of removing them after their productive life. The UH team created cost and project models for the Gulf of Mexico and will now work with Heriot-Watt University to apply to UK North Sea. UK North Sea has over 250 platforms and about 50,000 kilometers of pipelines. To see more of the projects click here.

“We wanted to bring in industry experts to not only assess the quality of the proposals but also to attract industry support of the projects,” assistant vice president for intellectual property and industrial engagement at UH Michael Harold said in a news release. “It’s a win-win —reviewers get a first look at cutting-edge ideas, and the projects have a chance to build industry interest for future development.”

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This article originally ran on EnergyCapital.