3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Stephanie Tsuru of SheSpace, Fareed Zein of Unytag, and Libby Covington of The Craig Group. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from smart city tech to startup marketing — recently making headlines in Houston innovation.

Stephanie Tsuru, founder of SheSpace

Stephanie Tsuru joins this week's Houston Innovators Podcast to share her growth plans for 2023. Photo via LinkedIn

SheSpace opened with a splash, Founder Stephanie Tsure tells InnovationMap on last week's episode of the Houston Innovators Podcast. After surviving through the pandemic, the female-focused coworking hub expanded — with a new type of membership as well as physically.

"We had so many people who wanted to be a part of the community — so we started a social networking group," she says.

Now, the entrepreneur is looking to expand this year to open satellite locations. She shares more on the show. Read more.

Fareed Zein, founder of Unytag

Unytag celebrated a big win at the Ion recently — and has taking its prizes into the new year. Photo via LinkedIn

As the father of four competitive-tennis-playing daughters, Fareed Zein spent years driving “from California to Florida,” he says. Throughout those years, he and his wife racked up toll violation after toll violation. “I thought, there’s got to be an easier way,” he recalls.

Fortunately, Zein wasn’t just any sports dad with thousands of miles on his car. The University of Texas grad put in 26 years developing IT systems at Shell. He retired from that role in 2015, which allowed him to spend more time on the road with his youngest daughter, now playing for UT Austin. In 2019, he used his technology expertise to start Unytag, a company focused on making it easier to drive around the country as the Zein family had so many times.

Unytag is a system that allows users to trash their multiple toll tags in favor of just one RFID (radio-frequency identification) sticker and an app. The app, which Zein says is currently in its testing phase, will be available on both IOS and Android phones in the second half of the year.

“A phone is a device everyone has nowadays, right?” says Zein. “Just like you use your phone to pay for a latte at Starbucks, we are going to simplify how you pay tolls.” Read more.

Libby Covington, partner at The Craig Group

It's undeniable that businesses are facing economic uncertainty in 2023. Here's what marketing tools to tap into to navigate the challenges ahead. Photo via LinkedIn

Make 2023 the year of optimized marketing for your startup — that's Libby Covington's advice. Partner at The Craig Group, she outlined her tips in a guest column for InnovationMap.

"Continued growth starts with goal setting and coming up with a marketing and business development strategy that fits the unique needs of a business," she writes. "This works most effectively when a company’s management team ensures that marketing and sales are working in lockstep. They are two sides of the same coin and need to see themselves that way to maximize results and therefore profit." Read more.

Unytag celebrated a big win at the Ion recently — and has taking its prizes into the new year. Photo via Ion/Facebook

Houston startup with innovative transportation app gets boost from pitch competition

tag, you're it

How many times have you accidentally taken a toll road without a tag? Or traveled to a part of the country where the toll system is different than the one for which you already paid up?

As the father of four competitive-tennis-playing daughters, Fareed Zein spent years driving “from California to Florida,” he says. Throughout those years, he and his wife racked up toll violation after toll violation. “I thought, there’s got to be an easier way,” he recalls.

Fortunately, Zein wasn’t just any sports dad with thousands of miles on his car. The University of Texas grad put in 26 years developing IT systems at Shell. He retired from that role in 2015, which allowed him to spend more time on the road with his youngest daughter, now playing for UT Austin. In 2019, he used his technology expertise to start Unytag, a company focused on making it easier to drive around the country as the Zein family had so many times.

Unytag is a system that allows users to trash their multiple toll tags in favor of just one RFID (radio-frequency identification) sticker and an app. The app, which Zein says is currently in its testing phase, will be available on both IOS and Android phones in the second half of the year.

“A phone is a device everyone has nowadays, right?” says Zein. “Just like you use your phone to pay for a latte at Starbucks, we are going to simplify how you pay tolls.”

Another beauty of the Unytag system is that — rather than depositing a set amount as users do for most toll systems — it’s pay-as-you-go. Funds are withdrawn by Unytag just as they are needed. And it works for every toll tag in the country, with plans to expand globally.

Though Zein brought technical chops to Unytag, he still had to learn to be a founder. He credits his time participating in the Founder Institute’s pre-seed accelerator with helping him to launch from the ground up.

“From there, I decided I needed to start building the infrastructure that I needed,” Zein recalls.

Next, he worked with the Texas Venture Labs accelerator and was named a finalist at the 2022 Houston Innovation Awards Gala. Most recently, Unytag won last November’s Houston Startup Showcase, with a prize of $10,000 from The Ion and $20,000 in legal services from Ion partner Baker Botts.

“That was a pretty big confidence builder that we are going in the right direction as well as a great way to start the year for us,” Zein says.

Opportunities like those are a just some of what Zein says makes him proud to be a “Houston born and raised” company. With his extended network built over 32 years living in the Houston area, Zein says, he’s had many opportunities for growth that he might not have found elsewhere. Two of his current team members were colleagues at Shell.

“Having an ecosystem that supports innovation is exactly what we needed,” he adds. “We are very proud of the future of tech startups in Houston with The Ion and the Innovation District, where we continue to grow. We’re ready to create the next success story.”

Fareed Zein has racked up his fair share of toll bills — and he designed a better way. Photo courtesy of Unytag

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Eli Lilly scoops up Houston biotech startup in $300 million deal

big pharma deal

Pharmaceutical giant Eli Lilly has acquired Houston biotech startup CrossBridge Bio, which develops antibody-drug conjugates for cancer, in a deal worth up to $300 million. The deal was celebrated by TMC Venture Fund and the University of Texas Health Science Center at Houston last week.

CrossBridge, founded in 2023, is developing ADCs based on research by Kyoji Tsuchikama and Zhiqiang An, both of UT Health Houston. Tsuchikama is an associate professor of medicinal chemistry and a globally recognized ADC pioneer, and An is a professor of molecular science and vice president of drug discovery.

Antibody-drug conjugates (ADCs) are a potent combination of targeted therapy and chemotherapy that kills cancer cells while saving healthy tissue.

Clinical trials for CrossBridge’s primary ADC candidate, CBB-120, are expected to start this year, pending approval from the U.S. Food and Drug Administration (FDA).

“I’m proud of how well our team has executed and advanced our platform in such a short time since the company’s founding,” Michael Torres, co-founder and CEO of CrossBridge, said in a news release. “By becoming a part of Lilly, a leader in patient-focused therapeutic development, we are well-positioned to further accelerate the clinical potential of this approach.”

Under the Lilly deal, CrossBridge shareholders were expected to receive an upfront payment along with a follow-up payment based on the achievement of certain milestones.

In 2024, CrossBridge closed a $10 million seed round. Among the investors in CrossBridge are the Texas Medical Center Venture Fund, CE-Ventures, Alexandria Venture Investments, Portal Innovations, Linden Lake Labs, and the Cancer Prevention and Research Institute of Texas (CPRIT). It was formed in TMC Innovation’s Accelerator for Cancer Therapeutics program."Built within the TMC ecosystem, CrossBridge Bio grew with the support, funding, and resources that helped shape its trajectory. TMC led the company's early financing and watched it evolve from its earliest days to its acquisition by Eli Lilly," William McKeon, president and CEO of the Texas Medical Center, shared in a LinkedIn post. "[This is a] strong reminder that breakthrough science and the right early backing can change what’s possible."

7 Houston neighbors named to U.S. News' best places to live in 2026

Living Well

Several Houston suburbs have been crowned the best places to live in the U.S. for 2026, according to U.S. News & World Report. Sugar Land is the highest-ranked city in the Houston metro, and it ranks as the 10th best place to live in the country.

The annual list of Best Places to Live in the U.S. is designed to help readers make the most informed decisions when choosing where to settle down, using data from sources such as the U.S. Census Bureau, Department of Commerce, the Federal Reserve and the Bureau for Economic Analysis, as well as state and local sources.

For the 2026-2027 rankings, U.S. News featured 250 U.S. cities and ranked them across four livability indexes — quality of life, value, desirability, and job market — weighted by importance based on survey results of approximately 500 Americans. The rankings were also broken down state-by-state, as well as the best big, medium, and small cities overall.

Sugar Land is the No. 4 best places to live in Texas, and it soared into the No. 10 spot overall in the nation after ranking 16th last year. Sugar Land also ranks as the fourth-best mid-sized city to live in America for 2026-2027.

According to U.S. News, Sugar Land's median household income is far higher than the national average. Residents make $140,511 per year, while the average American household income is only $83,181.

Additionally, the $431,815 median home value in Sugar Land is also far greater than the $359,870 national average.

After ranking in the top 10 in the 2025 report, League City and Pearland now both rank outside the national top 10 for 2026. League City slipped from No. 6 to No. 13 this year, while Pearland dropped from No. 3 nationwide to No. 16.

These three Houston suburbs also boast highly desirable job markets for potential newcomers or current residents that want to start or change their career.

Houston proper, however, remains outside of the top 250 and is the 327th best place to live in the U.S., and it's the 60th best place to live in Texas.

Other cities in the greater Houston area that ranked among the top 100 include:

  • No. 28 – The Woodlands
  • No. 38 – Katy
  • No. 61 – Missouri City
  • No. 82 – Spring

The Lone Star State had a "strong showing" in the overall top 10 thanks to its "high affordability scores," a release said. Besides Sugar Land, three more popular Texas suburbs made the cut: Leander (No. 8) outside Austin and Dallas-Fort Worth suburbs Flower Mound (No. 3) and Frisco (No. 9).

"As prices of everyday goods continue to rise, consumers are considering affordability as a top priority when choosing a place to live," said U.S. News consumer lending analyst Erika Giovanetti. "While U.S. News’ consumer survey indicated that quality of life and affordability were close in importance, cost-of-living concerns resulted in many Americans putting what they can afford above their aspirations."

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This article originally appeared on CultureMap.com.

7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

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