3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Stephanie Tsuru of SheSpace, Fareed Zein of Unytag, and Libby Covington of The Craig Group. Photos courtesy

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from smart city tech to startup marketing — recently making headlines in Houston innovation.

Stephanie Tsuru, founder of SheSpace

Stephanie Tsuru joins this week's Houston Innovators Podcast to share her growth plans for 2023. Photo via LinkedIn

SheSpace opened with a splash, Founder Stephanie Tsure tells InnovationMap on last week's episode of the Houston Innovators Podcast. After surviving through the pandemic, the female-focused coworking hub expanded — with a new type of membership as well as physically.

"We had so many people who wanted to be a part of the community — so we started a social networking group," she says.

Now, the entrepreneur is looking to expand this year to open satellite locations. She shares more on the show. Read more.

Fareed Zein, founder of Unytag

Unytag celebrated a big win at the Ion recently — and has taking its prizes into the new year. Photo via LinkedIn

As the father of four competitive-tennis-playing daughters, Fareed Zein spent years driving “from California to Florida,” he says. Throughout those years, he and his wife racked up toll violation after toll violation. “I thought, there’s got to be an easier way,” he recalls.

Fortunately, Zein wasn’t just any sports dad with thousands of miles on his car. The University of Texas grad put in 26 years developing IT systems at Shell. He retired from that role in 2015, which allowed him to spend more time on the road with his youngest daughter, now playing for UT Austin. In 2019, he used his technology expertise to start Unytag, a company focused on making it easier to drive around the country as the Zein family had so many times.

Unytag is a system that allows users to trash their multiple toll tags in favor of just one RFID (radio-frequency identification) sticker and an app. The app, which Zein says is currently in its testing phase, will be available on both IOS and Android phones in the second half of the year.

“A phone is a device everyone has nowadays, right?” says Zein. “Just like you use your phone to pay for a latte at Starbucks, we are going to simplify how you pay tolls.” Read more.

Libby Covington, partner at The Craig Group

It's undeniable that businesses are facing economic uncertainty in 2023. Here's what marketing tools to tap into to navigate the challenges ahead. Photo via LinkedIn

Make 2023 the year of optimized marketing for your startup — that's Libby Covington's advice. Partner at The Craig Group, she outlined her tips in a guest column for InnovationMap.

"Continued growth starts with goal setting and coming up with a marketing and business development strategy that fits the unique needs of a business," she writes. "This works most effectively when a company’s management team ensures that marketing and sales are working in lockstep. They are two sides of the same coin and need to see themselves that way to maximize results and therefore profit." Read more.

Unytag celebrated a big win at the Ion recently — and has taking its prizes into the new year. Photo via Ion/Facebook

Houston startup with innovative transportation app gets boost from pitch competition

tag, you're it

How many times have you accidentally taken a toll road without a tag? Or traveled to a part of the country where the toll system is different than the one for which you already paid up?

As the father of four competitive-tennis-playing daughters, Fareed Zein spent years driving “from California to Florida,” he says. Throughout those years, he and his wife racked up toll violation after toll violation. “I thought, there’s got to be an easier way,” he recalls.

Fortunately, Zein wasn’t just any sports dad with thousands of miles on his car. The University of Texas grad put in 26 years developing IT systems at Shell. He retired from that role in 2015, which allowed him to spend more time on the road with his youngest daughter, now playing for UT Austin. In 2019, he used his technology expertise to start Unytag, a company focused on making it easier to drive around the country as the Zein family had so many times.

Unytag is a system that allows users to trash their multiple toll tags in favor of just one RFID (radio-frequency identification) sticker and an app. The app, which Zein says is currently in its testing phase, will be available on both IOS and Android phones in the second half of the year.

“A phone is a device everyone has nowadays, right?” says Zein. “Just like you use your phone to pay for a latte at Starbucks, we are going to simplify how you pay tolls.”

Another beauty of the Unytag system is that — rather than depositing a set amount as users do for most toll systems — it’s pay-as-you-go. Funds are withdrawn by Unytag just as they are needed. And it works for every toll tag in the country, with plans to expand globally.

Though Zein brought technical chops to Unytag, he still had to learn to be a founder. He credits his time participating in the Founder Institute’s pre-seed accelerator with helping him to launch from the ground up.

“From there, I decided I needed to start building the infrastructure that I needed,” Zein recalls.

Next, he worked with the Texas Venture Labs accelerator and was named a finalist at the 2022 Houston Innovation Awards Gala. Most recently, Unytag won last November’s Houston Startup Showcase, with a prize of $10,000 from The Ion and $20,000 in legal services from Ion partner Baker Botts.

“That was a pretty big confidence builder that we are going in the right direction as well as a great way to start the year for us,” Zein says.

Opportunities like those are a just some of what Zein says makes him proud to be a “Houston born and raised” company. With his extended network built over 32 years living in the Houston area, Zein says, he’s had many opportunities for growth that he might not have found elsewhere. Two of his current team members were colleagues at Shell.

“Having an ecosystem that supports innovation is exactly what we needed,” he adds. “We are very proud of the future of tech startups in Houston with The Ion and the Innovation District, where we continue to grow. We’re ready to create the next success story.”

Fareed Zein has racked up his fair share of toll bills — and he designed a better way. Photo courtesy of Unytag

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Houston researchers develop dissolvable implant for targeted cancer drug delivery

cancer research

Researchers at Houston Methodist have developed a biodegradable implant that can be used to safely and consistently deliver drug treatments to tumors and then dissolve without the need for further surgery.

The implant is only the size of a grain of rice, but its potential is staggering. The biodegradable nanofibrous drug-eluting seed (b-NDES) works as a reservoir parked inside a soft tumor, where it can slowly release immune-stimulating drugs over time. This overcomes a consistent problem with drugs such as immune checkpoint inhibitors. Normal systemic administration sees comparatively little of the drug making its way to the tumor, with most of it circulating throughout the body. The b-NDES is like deploying a small guerrilla fighting force embedded in enemy territory, doing maximum damage to the entrenched tumor.

"To improve cancer treatment, we're trying to start a fire inside the tumor itself," Corrine Chua, associate professor in the Center for BioNanoengineering at Houston Methodist Research Institute, said in a news release. "By activating immune cells directly within the tumor microenvironment, those cells can then travel throughout the body and seek out cancer wherever it exists. The b-NDES platform was developed to help keep therapeutic drugs concentrated inside tumors while minimizing exposure to healthy tissues.”

Chua co-led the study with Alessandro Grattoni, chair and director of the Center for BioNanoengineering at Houston Methodist Research Institute.

The study included support from the Nancy Owens Breast Cancer Foundation and the National Institutes of Health/National Cancer Institute.

Chau and Grattoni used preclinical models of triple-negative breast cancer, an aggressive form of cancer that is estrogen receptor-negative, progesterone receptor-negative and HER2-negative. Because of the receptor negativity, some popular treatments like tamoxifen and trastuzumab are ineffective. Chemotherapy has been shown to be the best course of action.

The b-NDES implant is deployed alongside radiation drugs. It keeps the drugs focused on the tumor, reducing the amount of harmful side effects typically seen when drugs are circulated more widely in the body. In 60 percent of the models, tumors were eliminated and did not cause side effects beyond the tumor site. Once the drugs have been deployed, the implant breaks down naturally.

While promising, more research will have to be done to expand use to other tumor types.

"Although the study focused on triple-negative breast cancer models, the approach could have broader applications for solid tumors," Grattoni added in the release. "It could potentially be used in cancers where there is a tumor lesion accessible for placement, including pancreatic or lung cancers."

New Houston platform Same Day Reels launches for on-demand content creation

In The Moment

If an event doesn't happen on Instagram, did it even really happen? In today's social media-driven age of branding and audience engagement, the answer increasingly is no.

Houston entrepreneur Karen De Amat is looking to fill the online content creation needs of companies with her new venture, Same Day Reels, which launched in early August. It will serve as a platform to connect companies and brands with talent that can help turn an event into a viral moment as it is happening.

"Events move quickly, and social media moves even faster,” said De Amat. “Same Day Reels was built to help brands capture the moment while it still matters. We are creating a more efficient way for businesses and creators to work together. Brands need content faster, and creators need more opportunities to turn their talent into real work. Same Day Reels brings those needs together.”

The company is focused on adding livestreams and concurrent short video content to "activations, launches, fundraisers, grand openings, conferences, hospitality experiences, and private celebrations." Such content can significantly increase the visibility of a product or brand according to digital marketing brands like Wyzowl, whose data found 63 percent of people in 2026 prefer to learn about new products via short video.

Packages offered by Same Day Reels will include filming, editing, and publishing content within hours of the targeted event.

De Amat says that her content creation platform will be a way to preserve the excitement of events and launches by enshrining them with immediate social media-driven memories.

“Event content is no longer just something you post after the fact,” De Amat said. “It is part of how people experience, remember and share the moment.”

Previously, De Amat is also the founder and CEO of Social Behavior, an influencer marketing company she launched from her home in 2014. It quickly garnered an array of clients and thrust De Amat into the spotlight, including numerous appearances on Fox 26's The Isiah Factor. Influencer Marketing Hub named her one of the top CEOs of influencer marketing companies in Houston in 2025.

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This article originally appeared on CultureMap.com.

Bristol Myers Squibb to build $2.3B Houston pharma manufacturing campus

coming soon

New Jersey-based pharmaceutical giant Bristol Myers Squibb Co. has officially named Houston as the home of its new state-of-the-art manufacturing site.

The 60,000-square-foot facility represents a $2.3 billion investment, according to a news release. It is expected to create 500 skilled jobs and will be located in Houston's Generation Park.

BMS first announced that it was considering Houston among 16 other cities for the facility in May. The new hub will manufacture small molecule, biologic and antibody-drug conjugates and is part of a $40 billion commitment to invest in the United States over five years. Construction is slated to begin next year, with the facility coming online in 2030.

"We're building the domestic manufacturing capabilities needed to deliver the next generation of medicines and support future scientific breakthroughs. Houston and the state of Texas offer the talent, infrastructure, and partnership needed to help bring that vision to life," Christopher Boerner, CEO and board chair of BMS, said in the release.

The new facility will feature a modular, multi-modal design, which will allow the company to reconfigure and add to its manufacturing capabilities over time. BMS says it expects the facility to "(grow) in scale and capability well beyond its opening configuration."

"Our decision to build this state-of-the-art manufacturing campus in Houston, Texas, reflects our confidence in the region’s ability to support a world-class, digitally advanced supply operation,” Karin Shanahan, EVP and chief supply chain and operations officer of BMS, added in the release. “This facility is designed to deliver the speed, quality, and reliability that patients depend on, combining flexible, modular manufacturing with advanced digital capabilities to ensure consistent supply across multiple modalities. It strengthens our ability to operate with resilience and positions us to reliably deliver medicines to patients today while adapting future demands.”

Texas Gov. Greg Abbott shared that the state has granted BMS a $4.89 million Texas Enterprise Fund (TEF) grant for the project. TEF grants, administered by the Texas Economic Development & Tourism Office, support business relocation or expansion projects that create "new, good-paying jobs in the community and attract significant new capital investment to the state." The development is also a qualified project under the Texas Jobs, Energy, Technology, and Innovation (JETI) program.

“Texas is a global hub for life sciences, where today’s innovations shape the future of healthcare,” Abbott said in a news release. “This $2.3 billion investment by Bristol Myers Squibb in the dynamic biotech ecosystem in Houston is a testament to the depth of our skilled workforce and the pipeline of talent coming through our nation-leading technical colleges and research universities. With lower operating costs and easy access to markets across the U.S. and the world, Texas drives affordability for consumers.”

"Bristol Myers Squibb’s announcement is a tremendous win for Texas and the Houston region, further reinforcing our position as a premier destination for life sciences and advanced manufacturing,” added Greater Houston Partnership President and CEO Steve Kean.

Last fall, Eli Lilly and Co. selected Generation Park, a 4,300-acre, master-planned commercial district near Lake Houston, for its $6.5 billion manufacturing plant. More than 300 locations in the U.S. competed for the factory. Read more here.

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