From oil and gas deals to finance-focused initiatives, this week's innovators are ones to watch. Courtesy photos

As Houstonians head back to work or school following a fun summer break, we know two things for sure.

The first is that traffic will get back to its headache inducing craziness and that Houston startup news will only get more frequent. This week's innovators to know include oil and gas entrepreneurs with big deals on the line plus a finance-savvy woman who wants to encourage others to take control of their personal finance.

Tara Karimi, co-founder and chief scientist at Cemvita Factory

Cemvita Factory

Courtesy of Cemvita Factory

A brother-sister team has taken a huge step forward with their biotech startup, Cemvita Factory. Moji Karimi, who has a background in the oil and gas industry, and his sister, Tara, who has a background in biotech, teamed up a few years ago to create a technology that can mimic photosynthesis, turning carbon dioxide into glucose. It was Tara who figured out the technique and then the two worked backward to identify the industries — oil and gas and space — to work within.

Now, Cemvita is celebrating an investment from an Occidental Petroleum subsidiary — Oxy Low Carbon Ventures LLC.

"We have an ambitious goal to take one gigaton of CO2 out of the carbon cycle in the next decade and are very excited about being a part of Occidental's journey to become a carbon-neutral company," says Tara, co-founder and chief scientist, in a release.

Read more about Cemvita Factory here.

Travis Parigi, founder and CEO of LiquidFrameworks

Courtesy of LiquidFrameworks

Travis Parigi has built his software company from the ground up. Now, for the first time, he's thinking strategically about growth, thanks to a new financial partner.

Parigi's company, LiquidFrameworks, is an enterprise software company with applications in the upstream and downstream services industry. While the software focuses on automation and AI applications, Parigi tells InnovationMap that he has his eyes on emerging technology all the time. I keep a keen watch on a lot of the different technologies that are emerging out there.

"Blockchain is certainly one of them that we're looking at," Parigi says. "I think there's some interesting things that we might be able to do with that as it relates to price book management, which is complex and varied. It could be that blockchain could end up providing a nice mechanism for both parties to independently have pricing data verified."

Read more about Parigi and LiquidFrameworks here.

Eryn Schultz, co-founder of pHERsonal Finance Day

Courtesy of pHERsonal Finance Day.

Eryn Schultz wanted to encourage women to take control of their finances. So she created her own holiday for it called pHERsonal Finance Day. She hosted Houston panels and talks on the day — Friday, August 23 — and motivated women everywhere to take a moment and make a smart financial plan.

"In a world of women's marches and the 'Future is Female' t-shirts, women should be stepping up to shape their financial futures," Schultz writes in a guest column for InnovationMap. "For that reason, women should take a financial health day."

Schultz had a great turnout and reception for the Houston event, and she's already planning for next year.

Read more about pHERsonal Finance Day here.

August 23 is pHERsonal Finance Day — a day dedicated to education about financial practices for women. Getty Images

Why women should take a personal finance day from this Houston founder

Guest column

You've seen the statistics on Americans' financial health. The average American is not in great shape: $6,000 per person in credit card debt, $4,900 per person in student loan debt, and 51 percent of all workers who feel they aren't saving enough for retirement.

You also probably know about two other trends: women are living longer than men and divorcing at higher rates. What you may not know is that in 2019, most married women still say their husbands manage their finances. Even more surprisingly, millennial women have their husbands manage their financial futures at higher rates than their mothers. According to a 2017 UBS survey, 61 percent of millennial married women say their husbands manage their finances versus 54 percent of boomers. How do these trends come together?

Each year, there are two million American women who get divorced or widowed. These women grapple with a traumatic life event while trying to figure out the passwords to their investment accounts. In addition, married women are waking up to discover their retirement savings are short of their expectations. In a world of women's marches and the "Future is Female" t-shirts, women should be stepping up to shape their financial futures. For that reason, women should take a financial health day.

What's a financial health day? It's 24-hours where you take the day off work or dedicate a Sunday to writing down the balances of your investment accounts, renegotiating your auto insurance, and deciding if you should roll over that old 401K. A financial health day is not going to magically wipe away your student loans or solve your spending problem, but it can give you a plan for paying off debt or your mortgage three years early.

There is growing consensus on what being financially healthy means: you should maintain a four to six-month emergency fund, carry zero credit card debt, and contribute 10 to 20 percent of your monthly income to a retirement fund. Additional goals, like buying a house or paying for your kids' college, don't come until you have achieved a stable foundation.

Along with knowing what "financial health" means, there is also general agreement among financial experts on the best ways to achieve it:

  • Know your money situation. Physically write out your loans (credit cards, auto loans) with their interest rates, and all of your savings (including retirement). Seeing it all in one place will help you figure out your priorities.
  • Create money goals. Set multiple goals and prioritize them (you can also fund more than one goal at once). Is it saving for the down payment on a house or becoming debt free?
  • Track your spending. Where is your money going? There are budgeting apps from Mint or YNAB to help you keep track. Are there places where you can tweak your spending habits to fund your savings goal? Can you cancel a recurring expense you aren't using? Could you negotiate a better rate on your phone bill?
  • Automate to achieve your goals. Set up recurring payments to your debt and savings. Automated monthly transfers from your checking account to your savings goals make sure you aren't as tempted to spend that money. Schedule monthly and yearly calendar alerts to check your spending, rebalance your portfolio, etc. One advanced tip is to enroll in your 401K plan's "save more later" option. This will increase the percentage of your paycheck you put into your 401K annually.

These items seem simple. Yet, why are so few people doing them? It takes a LOT of work to get this money infrastructure set up. At the end of a long day of client meetings, chasing a toddler, or some combo of the two, it's difficult to muster the mental energy to address your finances – especially if you have the option of outsourcing this responsibility to a capable partner. That's where a day dedicated to your financial to-dos will help. You don't need to be solely in charge of your money, but you definitely need to understand the plan.

While we feel that everyone can benefit from a financial health day, the first pHERsonal Finance Day targeted to millennial women is scheduled for August 23. Check out our schedule if you want to get started. If taking a whole day off feels like a long-shot, take this quiz here to help you prioritize your financial to-dos. Whether it's a daily money minute or an appointment with a financial adviser (pick one who is a fiduciary), what are you doing to own your financial future?

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Eryn Schultz is the co-founder of pHERsonal Finance Day.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”