The 22nd annual Rice Business Plan Competition named its winners across life science, clean energy, software, and more. Photo via Rice University/Twitter

Rice University brought back its international student startup competition to its in-person format in a big way, giving out nearly $2 million in investment plus thousands more in-kind prizes to over a dozen winning teams.

The 2022 Rice Business Plan Competition took place April 7-9 on campus, ending in a banquet and awards presentation at the Marriott Marquis on Saturday. Earlier this year, Rice announced the 42 student teams competing for the awards. The student competitors represent 31 universities — including three from European universities. The 42 teams were narrowed down from over 400 applicants and divided into five categories: energy, cleantech and sustainability; life sciences and health care solutions; consumer products and services; hard tech; and digital enterprise.

Over 250 judges, mentors, and investors were involved in the competition, naming seven finalists — each receiving thousands of dollars in investment funding.

Here were this year's finalists — and what they walked away with:

  • LIDROTEC from RWTH Aachen University, a cutting-edge machine that can better cut microchips for the semiconductor industry, is the big winner this year, taking home the $350,000 GOOSE Capital Investment Grand Prize. The team also won: the Softeq Venture Studio Prize ($50,000 cash, $75,000 in-kind), the TiE Houston Angels Investment Prize ($100,000), RBPC Alumnus, Thomas Healy, Investment Prize ($50,000), the Eagle Investors Prise ($5,000), Best Elevator Pitch - Hard Tech ($500), and RG Advisors CFO Consulting In-Kind Prize. The company also received a $6,700 in-kind prize from BakerBotts and an in-kind $25,000 from RG Advisory. The company's prize totaled over $682,200 in investment and in-kind awards.
  • The second place winner was Hoth Intelligence of University of Pittsburgh, an artificial intelligence platform for health care providers, securing a $100,000 investment prize. The company also won the Owl Investment Prize ($155,000), the HAN Investment Prize ($100,000), and the Pearland EDC Spirit of Entrepreneurship Prize ($25,000). The company also received a a $6,700 in-kind prize from BakerBotts. The company's prize totaled $386,700 in investment awards.
  • Invitris from the Technical University of Munich — a synthetic biology startup targeting antibiotic-resistant bacteria — won third place, which came with a $50,000 award. The team also won the nCourage Courageous Women Entrepreneur Investment Prize ($40,000), the Best Elevator Pitch - Life Science award ($500), and a $6,700 in-kind prize from BakerBotts. bringing its total earnings to $97,200.
  • Winning fourth place and a $5,000 prize was LymphaSense of Johns Hopkins, a medical device startup that's created a wearable lymphedema detection device for at-risk patients. The company also won the TMC Innovation Healthcare Investment Prize ($250,000 and entry into the TMC accelerator) and the Nixon Institute Prize ($3,000). The company's total winnings was $258,000.
  • INIA Biosciences from Boston University — a health tech startup that's created a bioelectric wearable device for kidney donor recipients — won fifth place and $5,000 in prize money.
  • The sixth place winner was Bold Move Beverages, a canned coffee cocktail company from the University of Texas at Austin, which won $5,000 for placing sixth and $10,000 from the RBPC Alumnus, Thomas Healy, Investment Prize. The company won a total of $15,000.
  • Lastly for the finalists, Anise Health of Harvard University, a digital health startups with an inclusive, data-driven platform for culturally-adapted mental health treatment, won seventh place and the $5,000 prize. The company also won first place in the wildcard round, which came with a $2,000 Edward H. Molter Memorial Prize. Anise walked away with $7,000 total.
Several companies won monetary prizes outside of the seven finalists. Here's what other student-founded companies in the competition won:
  • Mallard Bay Outdoors from Louisiana State University, an online marketplace for securely booking outdoor activities, won $216,500 in cash and in-kind prizes. The company won the Owl Investment Prize ($65,000), the Softeq Venture Studio Prize ($50,000 cash, $75,000 in-kind), the RBPC Alumnus, Thomas Healy, Investment Prize ($25,000), the Anbarci Family Company Showcase Prize ($1,000), and the Best Elevator Pitch - Consumer ($500).
  • TransCrypts from the University of Toronto and Harvard University, a secure blockchain platform for sharing employee documents, won two awards — the Owl Investment Prize ($50,000) and the Best Elevator Pitch - Digital ($500) — for a total of $50,500 in prizes.
  • Advanced Optronics of Carnegie Mellon University, a health tech company that develops smart sensors to improve patient outcomes, won two awards — the Pediatric Device Prize ($25,000) and the OFW Law FDA Regulatory Strategy In-Kind Prize — for a total of more than $25,000 in cash and in-kind prizes.
  • EpiSLS — a novel medical device startup that's automating in-vivo allergy testing — of the University of Michigan won the $25,000 Pediatric Device Prize.
  • Farm-to-closet women's apparel brand Pareto of Stanford University won the $10,000 nCourage Courageous Women Entrepreneur Investment Prize.
  • EpiFresh of Rice University, which developed a protective produce coating material that reduces food waste, won three awards for a total of $27,000. The company won the Energy, Cleantech & Sustainability Prize ($25,000), the Anbarci Family Company Showcase Prize ($1,000), and the Overall Best Elevator Pitch ($1,000).
  • Mantel of MIT, which is developing a high temperature liquid phase carbon capture material, won two awards for a total of $28,000 in prizes. The company won the New Climate Ventures Investment Prize ($25,000) and the DK Innovation Prize ($3,000).
  • Invictus BCI — a health tech startup building a noninvasive brain computer interface tools — from MIT won the the RBPC Alumni Network NABACO Prize for a total of $10,000 in winnings.
  • Health care fintech solution Woobie of Brigham Young University won the $25,000 Urban Capital Network Investment Prize.
  • KLAW Industries of Binghamton University, which has designed a way to recycle glass into concrete, won the Anbarci Family Company Showcase Prize ($1,000) and the Best Elevator Pitch - Energy ($500) prizes for a total of $1,500 in awards.
  • Acorn Genetics of Northwestern University, which is better optimizing genetic data for patients, won second place for the wildcard round, which came with the Edward H. Molter Memorial Prize ($1,750).
  • AI-powered stroke prevention platform PLAKK from McGill University won third place for the wildcard round, which came with the Edward H. Molter Memorial Prize ($1,500).
These startups join the ranks of 269 successful RBPC alumni companies — with 50 exits, five IPOs, and over $4.6 billion raised. RBPC was established in 2001.
The Rice Business Plan Competition is back in person this year, and these are the 42 teams that will go head to head for investments and prizes. Photo courtesy of Rice University

Rice University's student startup competition names 42 teams to compete for over $1 million in prizes

ready to pitch

The Rice Alliance for Technology and Entrepreneurship and the Jones Graduate School of Business have announced the 42 student teams that will compete in the 2022 Rice Business Plan Competition, which returns to an in-person format on the Rice University campus in April.

Of the teams competing for more than $1 million in prizes and funding in this year's competition, six hail from Texas — two teams each from Rice University, University of Texas at Austin, and Texas A&M University. The student competitors represent 31 universities — including three from European universities. The 42 teams were narrowed down from over 400 applicants and divided into five categories: energy, cleantech and sustainability; life sciences and health care solutions; consumer products and services; hard tech; and digital enterprise.

This is the first in-person RBPC since 2019, and the university is ready to bring together the entrepreneurs and a community of over 250 judges, mentors, and investors to the competition.

“As we come out on the other side of a long and challenging two years, we're feeling a sense of renewal and energy as we look to the future and finding inspiration from the next generation of entrepreneurs who are building a better world,” says Catherine Santamaria, director of the RBPC, in a news release.

“This year's competition celebrates student founders with a strong sense of determination — founders who are ready to adapt, build and grow companies that can change the future,” she continues. “We hope their participation will provide guidance and inspiration for our community.”

According to a news release, this year's RBPC Qualifier Competition, which narrowed down Rice's student teams that will compete in the official competition, saw the largest number of applicants, judges, and participants in the competition’s history. The Rice Alliance awarded a total of $5,000 in cash prizes to the top three teams from the internal qualifier: EpiFresh, Green Room and Anvil Diagnostics. From those three, Rice teams EpiFresh and Green Room received invitations to compete in the 2022 RBPC..

The full list of student teams that will be competing April 7 to 9 this year include:

  • Acorn Genetics from Northwestern University
  • Advanced Optronics from Carnegie Mellon University
  • Aethero Space from University of Missouri
  • AImirr from University of Chicago
  • AiroSolve from UCLA
  • Algeon Materials from UC San Diego
  • Anise Health from Harvard University
  • Beyond Silicon from Arizona State University
  • Bold Move Beverages from University of Texas at Austin
  • Diamante from University of Verona
  • EarthEn from Arizona State University
  • Empower Sleep from University of Pennsylvania
  • EpiFresh from Rice University
  • EpiSLS from University of Michigan
  • Green Room from Rice University
  • Horizon Health Solutions from University of Arkansas
  • Hoth Intelligence from Thomas Jefferson University
  • INIA Biosciences from Boston University
  • Invictus BCI from MIT
  • Invitris from Technical University of Munich (TUM)
  • KLAW Industries from Binghamton University
  • LIDROTEC from RWTH Aachen
  • Locus Lock from University of Texas at Austin
  • LymphaSense from Johns Hopkins University
  • Mallard Bay Outdoors from Louisiana State University
  • Mantel from MIT
  • Olera from Texas A&M University
  • OpenCell AI from Weill Cornell Medicine
  • OraFay from UCLA
  • Pareto from Stanford University
  • Photonect Interconnect Solutions from University of Rochester
  • PLAKK from McGill University
  • PneuTech from Johns Hopkins University
  • Rola from UC San Diego
  • RotorX from Georgia Tech
  • SimulatED from Carnegie Mellon University
  • SuChef from University of Pennsylvania
  • Symetric Finance from Fairfield University
  • Teale from Texas A&M University
  • Team Real Talk from University at Buffalo
  • TransCrypts from Harvard University
  • Woobie from Brigham Young University
Last year's awards had 54 student teams competing virtually, with over $1.4 million in cash and prizes awarded. Throughout RBPC's history, competitors have gone onto raise more than $3.57 billion in capital and more than 259 RBPC alumni have successfully launched their ventures. Forty RBPC startups that have had successful exits through acquisitions or trading on a public market, per the news release.
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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.