Plug and Play Technology Center has named its first 15 startups in its Houston Energy and Sustainability cohort. Getty Images

A Silicon Valley accelerator program has announced the companies that will participate in its first Houston cohort just as the program begins to foster energy tech innovation in town.

Plug and Play Technology Center, which announced its entry into the Houston market this summer, named the 15 companies that will complete the program. While there are only two Houston-based companies in the mix this time around, all 15 companies will be operating locally with Houston corporate partners and startup development organizations.

"By being a part of this Plug and Play cohort, our corporate partners have validated that there is an interest in these startups' technology solutions," says Payal Patel, director of corporate partnerships for Plug and Play in Houston. "This will encourage these non-Houston based startups to spend more time in Houston, likely (and hopefully) leading to them doing business with our corporations, raising money from local investors, hiring local talent, and setting up an office in Houston."

Patel says the selection process was similar to the due diligence done in investor research, since Plug and Play treats its startups like a portfolio of sorts. Plug and Play hosted a pitch night in September as a way to introduce the cohort finalists to the ecosystem before making the final selection.

"We used the technology focus areas of our corporate partners to source 100 startups with commercial viability in Houston," Patel says. "Through consultation with our partners and voting at our Selection Day event in September, we ultimately narrowed the group to 15 startups we believe we can provide value to over the next few months."

The startups are off to Plug and Play's headquarters in California for a Focus Week, Patel says, then will return to Houston for various corporat events, converences, and more as part of the program.

Here are the 15 companies that will participate in the energy and sustainability accelerator from Plug and Play Tech Center.

Alchera Inc.

Founded: 2016
Money raised: $6 million
Employees: 45 full time, 60 part time
Headquarters: South Korea
About: Alchera's technology uses artificial intelligence image to prevent the loss of lives and money in dangerous situations on site.

Ario Technologies Inc.

Founded: 2016
Moneyraised: $2.3 million
Employees: 8 full time, 1 part time
Headquarters: Norfolk, Virginia
About: Ario has a augmented reality technology that allows its users to search its data in the real world.

Blacksands Inc.

Founded: 2012
Moneyraised: $1 million
Employees: 5 full time, 7 part time
Headquarters: Sunnyvale, California
About: Blacksands has a secured connection as a service business model for fast-paced cybersecurity.

BlastPoint

Founded: 2016
Money raised: $1.3 million
Employees: 7 full time, 3 part time
Headquarters: Pittsburgh, Pennsylvania
About: Using internal insights and data, BlastPoint helps make innovative ideas a reality in the workplace.

ForePaas

Founded: 2015
Moneyraised: $10 million
Employees: 40 full time, 1 part time
Headquarters:
About: The ForePaas platform combines cloud-based technology and data applications to optimize and accelerate industrial internal enterprise data initiatives.

Capella Space

Founded: 2016
Money raised: $50 million
Employees: 50 full time, 0 part time
Headquarters: San Francisco
About: Capella Space is building a large commercial radar satellite constellation to speed up the informed decision making process for industrial workers down on earth.

Cumulus Digital Solutions

Founded: 2018
Money raised: $4.5 million
Employees: 14 full time, 4 part time
Headquarters: Cambridge, Massachusetts
About: Using data collection and cloud-based software, Cumulus is eliminating poor work quality that causes accidents in the field.

Data Gumbo

Founded: 2016
Money raised: $3.2 million
Employees: 19 full time, 4 part time
Headquarters: Houston
About: Data Gumbo has developed a blockchain network for automated contract execution for industrial clients

Latium Technologies

Founded: 2019
Money raised: $1 million (Canadian)
Employees: 8 full time, 0 part time
Headquarters: Edmonton, Canada
About: Latium has developed a better industrial IoT platform for heavy industry.

Indegy

Founded: 2014
Money raised: $18 million
Employees: 53 full-time, 0 part-time
Headquarters: New York
About: Indegy specializes in real-time security for industrial campuses.

Ingu Solutions

Founded: 2014
Money raised: $2.1 million (Canadian)
Employees: 10 full-time, 0 part-time
Headquarters: Calgary, Canada
About: Ingu wants to revolutionize the economics of the pipeline industry with new technology and initiatives.

Cemvita Factory

Founded: 2017
Money raised: None disclosed.
Employees: 8 full time, 10 part time
Headquarters: Houston
About: Cemvita has patented technology that can mimic photosynthesis to lower carbon emissions.

KX

Founded: 1999
Money raised: None disclosed.
Employees: 2,500 full-time and 0 part-time
Headquarters: Northern Ireland
About: KX is a data company that uses its global technology in the finance, retail, pharma, manufacturing, and energy industries.

Ondaka Inc.

Founded: 2017
Money raised: $1.6 million
Employees: 8 full time, 2 part time
Headquarters: Palo Alto, California (has a local office at Station Houston)
About: Ondaka uses an alphabet soup of buzzword technologies — IoT, AI, VR — and allows oil and gas companies to really visualize their infrastructure.

Terrapin

Founded: 2016
Money raised: $3 million
Employees: 10 full time, 5 part time
Headquarters: Edmonton, Canada
About: Terrapin is a designer and developer of industrial heat recovery projects.

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Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

Elon Musk's SpaceX site officially becomes the city of Starbase, Texas

Starbase, Texas

The South Texas home of Elon Musk’s SpaceX rocket company is now an official city with a galactic name: Starbase.

A vote Saturday, May 3, to formally organize Starbase as a city was approved by a lopsided margin among the small group of voters who live there and are mostly Musk’s employees at SpaceX. With all the votes in, the tally was 212 in favor to 6 against, according to results published online by the Cameron County Elections Department.

Musk celebrated in a post on his social platform, X, saying it is “now a real city!”

Starbase is the facility and launch site for the SpaceX rocket program that is under contract with the Department of Defense and NASA that hopes to send astronauts back to the moon and someday to Mars.

Musk first floated the idea of Starbase in 2021 and approval of the new city was all but certain. Of the 283 eligible voters in the area, most are believed to be Starbase workers.

The election victory was personal for Musk. The billionaire’s popularity has diminished since he became the chain-saw-wielding public face of President Donald Trump’s federal job and spending cuts, and profits at his Tesla car company have plummeted.

SpaceX has generally drawn widespread support from local officials for its jobs and investment in the area.

But the creation of an official company town has also drawn critics who worry it will expand Musk’s personal control over the area, with potential authority to close a popular beach and state park for launches.

Companion efforts to the city vote include bills in the state Legislature to shift that authority from the county to the new town’s mayor and city council.

All these measures come as SpaceX is asking federal authorities for permission to increase the number of South Texas launches from five to 25 a year.

The city at the southern tip of Texas near the Mexico border is only about 1.5 square miles (3.9 square kilometers), crisscrossed by a few roads and dappled with airstream trailers and modest midcentury homes.

SpaceX officials have said little about exactly why they want a company town and did not respond to emailed requests for comment.

“We need the ability to grow Starbase as a community,” Starbase General Manager Kathryn Lueders wrote to local officials in 2024 with the request to get the city issue on the ballot.

The letter said the company already manages roads and utilities, as well as “the provisions of schooling and medical care” for those living on the property.

SpaceX officials have told lawmakers that granting the city authority to close the beach would streamline launch operations. SpaceX rocket launches and engine tests, and even just moving certain equipment around the launch base, requires the closure of a local highway and access to Boca Chica State Park and Boca Chica Beach.

Critics say beach closure authority should stay with the county government, which represents a broader population that uses the beach and park. Cameron County Judge Eddie Trevino, Jr. has said the county has worked well with SpaceX and there is no need for change.

Another proposed bill would make it a Class B misdemeanor with up to 180 days in jail if someone doesn’t comply with an order to evacuate the beach.

The South Texas Environmental Justice Network, which has organized protests against the city vote and the beach access issue, held another demonstration Saturday that attracted dozens of people.

Josette Hinojosa, whose young daughter was building a sandcastle nearby, said she was taking part to try to ensure continued access to a beach her family has enjoyed for generations.

With SpaceX, Hinojosa said, “Some days it’s closed, and some days you get turned away."

Organizer Christopher Basaldú, a member of the Carrizo/Comecrudo Nation of Texas tribe, said his ancestors have long been in the area, where the Rio Grande meets the Gulf.

“It’s not just important,” he said, “it’s sacred.”