Houston bio-based materials founder rebrands, evolves future-focused sustainability startup

HOUSTON INNOVATORS PODCAST EPISODE 255

Zimri T. Hinshaw, founder and CEO of Rheom Materials, joins the Houston Innovators Podcast. Photo courtesy of Rheom

At first, Zimri T. Hinshaw just wanted to design a sustainable, vegan jacket inspired by bikers he saw in Tokyo. Now, he's running a bio-based materials company with two product lines and is ready to disrupt the fashion and automotive industries.

Hinshaw founded Rheom Materials (née Bucha Bio) in 2020, but a lot has changed since then. He moved the company from New York to Houston, built out a facility in Houston's East End Maker Hub, and rebranded to reflect the company's newest phase and extended product lines, deriving from dozens of different ingredients, including algae, seaweed, corn, other fruits and vegetables, and more.

"As a company, we pivoted our technology from growing kombucha sheets to grinding up bacteria nanocellulose from kombucha into our products and then we moved away from that entirely," Hinshaw says on the Houston Innovators Podcast. "Today, we're designing different materials that are more sustainable, and the inputs are varied."

Now, in addition to Rheom's leather-like alternative, Shorai, the company has a plastic-like material, Benree, that's 100 percent bio based.

"The scope of what we were doing — both on what raw materials we were using and what we were creating just kept expanding and growing," Hinshaw says.

With that major evolution past just kombucha-based textiles, it was time for a new name, ideated by the company's technical team. "Rheom" is the combination of "rheology" — the study of how polymers flow — and "form."

Rheom has also built a state-of-the-art chemicals testing lab at its new facility after moving into it early last year.

"We've got a ton of capabilities now — and we've been growing those since the beginning," Hinshaw says. "Now we have all this testing equipment — things that pull materials apart, things that test the flexibility of materials."

Next up, Rheom, which is backed by Houston-based New Climate Ventures, among other VCs, will raise a series A funding round to continue supporting its growth.

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First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

funds granted

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

The 130,000-square-foot Resilience Manufacturing Hub is coming to the Second Ward. Photo houston.org

$32M resilience-focused hub to rise in Houston's East End

coming soon

A first-of-its-kind manufacturing hub designed to “future proof” residential, commercial, industrial, and public sector infrastructure is coming to Houston.

The 130,000-square-foot Resilience Manufacturing Hub will house functions such as R&D, manufacturing, and assembly for products aimed at improving the resilience of homes, office buildings, warehouses, and other components of the “built environment.”

“We are looking for any product or technology solution that can reduce the impact from the next generation of disasters … by helping people thrive, not just survive, in their own community,” says Richard Seline, co-founder and managing director of the Houston-based Resilience Innovation Hub. The innovation hub is a partner in the manufacturing hub.

Seline says the manufacturing hub, with an estimated price tag of $32 million, will directly employ about 60 people. He expects the facility to either generate or “upskill” about 240 off-site jobs.

The manufacturing hub will be built adjacent to the 300,000-square-foot East End Maker Hub, which is opened in Houston’s Second Ward neighborhood two years ago. Seline says five companies already have expressed interest in being tenants at the manufacturing hub, which is set to open by next summer.

The East End Maker Hub, a public-private endeavor, opened in the summer of 2021. Photo by Natalie Harms/InnovationMap

“We know that the supply chains keep failing over and over again in regard to responding to and rebuilding after disasters. This is a way to address that,” Seline says of the manufacturing hub.

Aside from the innovation hub and East End Maker Hub, partners in the manufacturing venture are the nonprofit Urban Partnerships Community Development Corp. (UPC) and modular construction company VEMAS. UPC is based in Houston, and VEMAS has a Houston office.

“The Resilience Manufacturing Hub is one of four pillars in UPC’s vision for an Invest Houston strategy to grow our economy from within by directly impacting middle-income employment — vital for the 1 million jobs projected as a gap in greater Houston’s long-term competitiveness,” says Patrick Ezzell, president and chairman of UPC and founder of the East End Maker Hub.

The manufacturing hub will work hand in hand with the innovation hub. The innovation hub assesses and addresses risks triggered by climate-produced, manmade, pandemic-related and cybersecurity threats. Hub participants work on innovations aimed at alleviating these risks.

In 2012, the National Academy of Sciences defined resilience as “the ability to prepare and plan for, absorb, recover from, and more successfully adapt to adverse events.” Those events include hurricanes and floods.

The resilience movement got a substantial boost last year thanks to passage of the federal Community Disaster Resilience Zones Act. The law allows for designation of resilience zones in communities that are at high risk of natural disasters and have limited resources. These zones will qualify for federal funding earmarked for resilience efforts.

Harris County scores nearly 98 out of 100 on the National Risk Index, generated by the Federal Emergency Management Agency (FEMA), putting it into the “very high” risk category for natural hazards.

Yet Harris County ekes out a score of 12.73 out of 100 for community resilience, landing it in the “very low” category. This means the county has a poor ability to prepare for natural hazards, adapt to changing conditions, and withstand and recover from disruptions.

Richard Seline is the co-founder and managing director of the Houston-based Resilience Innovation Hub. Photo courtesy

BUCHA BIO has raised over $1 million to grow its team, build a new headquarters, and accelerate its go-to-market strategy. Image courtesy of BUCHA BIO

Houston-based biomaterials company raises $1.1M to grow team, build new HQ

money moves

A Houston company that has created a plant-based material that can replace unsustainable conventional leathers and plastics has announced the close of its oversubscribed seed funding round.

BUCHA BIO announced it's raised $1.1 million in seed funding. The round included participation from existing partners New Climate Ventures, Lifely VC, and Beni VC, as well as from new partners Prithvi VC, Asymmetry VC, and investors from the Glasswall Syndicate, including Alwyn Capital, as well as Chris Zarou, CEO & Founder of Visionary Music Group and manager of multi-platinum Grammy-nominated rapper, Logic, the startup reports in a news release.

“I’m excited to back BUCHA BIO’s amazing early market traction," Zarou says in the release. "Their next-gen bio-based materials are game-changing, and their goals align with my personal vision for a more sustainable future within the entertainment industry and beyond.”

The company, which relocated its headquarters from New York to Houston in February, was founded by Zimri T. Hinshaw in 2020 and is based out of the East End Makers Hub and Greentown Houston.

BUCHA BIO has created two bio-based materials using bacterial nanocellulose and other plant-based components. The two materials are SHORAI, which can be used as a leather alternative, and HIKARI, a translucent material that is expected to be formally introduced in November.

The fresh funding will help the company to accelerate its move into the marketplace next year by securing co-manufacturers to scale production. Additionally, the company is growing its team and is hiring for a new supply chain lead as well as some technician roles.

Per the release, BUCHA BIO is working on constructing a new headquarters in Houston that will house a materials development laboratory, prototype manufacturing line, and offices.

BUCHA BIO has the potential to impact several industries from fashion and automotive to construction and electronics. According to the Material Innovation Initiative, the alternative materials industry has seen an increased level of interest from investors who have dedicated over $2 billion into the sector since 2015.

“The time for rapid growth for biomaterials is now," says repeat investor Eric Rubenstein, founding managing partner at Houston-based New Climate Ventures, in the release. "BUCHA BIO's team and technical development are advancing hand in hand with the demands of brand partnerships, and we are excited to support them as they capitalize on this global opportunity.”

3D Systems announced its acquisition of Volumetric and its plans to keep operations in Houston. Photo via Jordan Miller/Rice University

Houston bioprinting startup to be acquired for up to $400M

big move

Houston-based Volumetric Biotechnologies has gone from startup to nine-figure acquisition in a mere three years.

Volumetric, which makes 3D-printed human organs and tissues, agreed October 27 to be purchased by publicly traded 3D Systems, a Rock Hill, South Carolina-based company that specializes in 3D technology, for as much as $400 million. The cash-and-stock deal, expected to be completed this year, will provide $45 million at closing and up to $355 million if Volumetric reaches certain benchmarks.

"Volumetric is already successful in its space with innovative light-based bioprinting," says Jeffrey Graves, president and CEO of 3D Systems. "This acquisition and integration of Volumetric into the 3D Systems family advances our commitment to health care."

Founded in 2018, Volumetric is a privately held spin-out of Rice University's bioengineering department. Its co-founders are Jordan Miller, the company's president, and Bagrat Grigoryan, the chief operating officer. Volumetric participated in the San Francisco-based accelerator Y Combinator in 2020. Investors include two health care nonprofits, the Methuselah Foundation and Methuselah Fund.

Miller, an associate professor of bioengineering at Rice University, will join 3D Systems as chief scientist for regenerative medicine, and Grigoryan will come aboard as vice president of regenerative medicine.

In conjunction with the acquisition, 3D Systems and business partner United Therapeutics, based in Manchester, New Hampshire, will conduct R&D for organ and tissue manufacturing at Volumetric's 20,000-square-foot facility in Houston's East End Maker Hub. Last December, Volumetric moved its operations to the hub. The startup produces human organs and tissues like the liver, kidney, pancreas, lung, and heart using a combination of human cells and medical-grade plastics.

"The vital organs inside of the human body are the most complicated structures in the known universe," Miller says in a news release. "Just as a vibrant city needs roads, a vital organ needs vasculature. Our work to date at Volumetric has focused on 3D bioprinting the intricate blood vessel architecture that is crucial for the function of these organs."

Grigoryan says manufacturing human organs represents a "transformative opportunity" to combat organ diseases.

"Broadening our team's ability to deliver on the promise of organ therapy is a win for patients and medical care around the world, as well as Volumetric shareholders who believed in our promise from early phase development," Grigoryan says.

Friday, October 1, is Manufacturing Day Houston at East End Maker Hub. Image courtesy of EEEMH

Houston has all the ingredients to thrive as a manufacturing hub, says expert

guest column

Manufacturing is critical to building the economy on both local and national levels.

According to Deloitte and The Manufacturing Institute, 4.6 million U.S. manufacturing jobs will be needed by 2030. The National Association of Manufacturing estimates that each $1 spent in manufacturing adds $2.79 to the economy and each $1 earned in direct manufacturing labor income yields $3.14 in labor income elsewhere. Failing to fill these jobs could cost the U.S. $1 trillion and thwart economic growth.

Manufacturing is a win-win for Houston. With Houston's manufacturing sectors tied to the overall U.S. economy, the Greater Houston area has the opportunity to thrive as a manufacturing powerhouse by returning manufacturing to the U.S.

"Houston is an amazing city with a wide variety of entrepreneurs, inventors and industry specialties. To support these firms, we need tens of thousands of skilled employees in a plethora of manufacturing jobs. On the product side, they include Space, Medical Devices, Robotics, Additive Manufacturing, BioEngineering, and next generation energy devices. From the process side - refined products, chemicals, beverages and plastics," said Michael Holthouse, CEO and founder of Holthouse Foundation For Kids.

In an effort to increase awareness of these advanced manufacturing careers, TXRX East End Maker Hub is hosting Manufacturing Day Houston on Friday, October 1. The event is attracting hundreds of middle- and high-school youth along with their teachers from the Greater Houston area.

EEMH is opening its doors to allow students the opportunity to engage in hands-on experiences, demonstrations, and interact with subject matter experts to learn the latest technologies in Process Manufacturing, Product Manufacturing, Bioengineering, Virtual Reality, Robotics, 3D printing and more. The keynote speaker, Jim "Mattress Mack" McIngvale of Gallery Furniture, will open the event.

Manufacturing Day Houston is a local effort to join National Manufacturing Day and Creators Wanted, both industry initiatives supported by the National Association of Manufacturers and the Manufacturing Institute. Manufacturing Day Houston has been created to reshape the perception of the advanced manufacturing industry and help today's youth understand how they can match their talents with in-demand product and process manufacturing careers that average $87,185 annually.

While attractive, many of these skilled manufacturing jobs go unfilled due to misinterpretations about the industry and educational opportunities. Houston's community colleges and technical programs offer affordable training for these opportunities, which can be completed in two years or less.

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Michelle Wicmandy serves as a marketing consultant for Imagina Communications.

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Rice University opens biotech venture studio in TMC

rapidly scaling

In its mission to amplify and advance biotech innovation, Rice University has announced its latest initiative — a new lab focused on bringing life-saving medical technologies to commercialization.

Established to rapidly build companies based on Rice University's portfolio of over 100 patents, RBL LLC is a new biotech venture creation studio based in Texas Medical Center Helix Park. RBL comes on the heels of establishing the Rice Biotech Launch Pad, a biotech innovation accelerator that opened last year.

Paul Wotton, executive director of the Rice Biotech Launch Pad, co-founded RBL with his colleagues Omid Veiseh, Rice professor of bioengineering and faculty director of the Rice Biotech Launch Pad; Jacob Robinson, Rice professor of electrical and computer engineering; and Dr. Rima Chakrabarti, a physician scientist and venture capital investor with KdT Ventures.

“This is a pivotal moment for Houston and beyond,” Wotton, who serves as RBL’s managing partner, says in a news release from Rice. “Houston has rapidly emerged as a global life sciences powerhouse, blending cutting-edge research with early clinical applications at Rice and the city’s world-renowned hospital systems.

"Investors from across the nation are recognizing Houston’s potential, and with RBL, we’re building on that momentum," he continues. "We’ll not only amplify the work of the Rice Biotech Launch Pad but expand our reach across Texas, creating opportunities for biotech ventures statewide and driving growth for the biotech industry as a whole.”

Strategically located in TMC, RBL will collaborate with medical leaders, investors, corporations, and other players both in the same building and on the greater TMC campus.

“Leveraging Rice University’s Biotech Launch Pad breakthroughs and pairing it with the world-class translational infrastructure of TMC Helix Park well positions RBL to drive unprecedented advances in patient care,” William McKeon, president and CEO of the TMC, says in the release. “This partnership between academia, industry and health care is exactly what’s needed to transform medical discoveries into real-world solutions that improve lives globally.”

RBL is Rice's latest effort to bridge the gap between academia and biotech innovation, an effort led by Paul Cherukuri, Rice’s chief innovation officer, who reportedly spearheaded development of the new initiative.

“RBL is a game-changer for Rice, Houston and the global biotech community,” Cherukuri adds. “This venture not only accelerates the commercialization of our innovations but also sets a blueprint for other universities looking to maximize the real-world impact of their discoveries. By combining scientific expertise with entrepreneurial support from Day Zero together with strategic clinical partnerships in the TMC, we’re creating a model for driving large-scale biotech innovation that universities everywhere should aspire to replicate.”

Since the Rice Biotech Launch Pad was established, Motif Neurotech closed its series A round with an oversubscribed $18.75 million, the hub secured a $34.9 million grant, and a “living pharmacy” founded at the Launch Pad received industry validation.

“RBL provides a powerful platform to translate high-impact scientific discoveries into therapies that will dramatically improve patient outcomes,” Veiseh says. “Our goal is to rapidly bring Rice’s pioneering research into the clinic, delivering life-saving solutions to patients around the world.”

Houston hospital named among smartest in the nation

hi, tech

Houston hospitals are chock-full of smart people. But they’re also equipped with lots of “smart” technology. In fact, five local hospitals appear on Newsweek’s new list of the world’s best “smart” hospitals.

To compile the list, Newsweek teamed up with data provider Statista to rank the world’s top 330 hospitals for the use of smart technology. The ranking factors were electronic functionality, telemedicine, digital imaging, artificial intelligence (AI), and robotics.

The highest-ranked Houston hospital is the University of Texas MD Anderson Cancer Center, appearing at No. 6. The hospital was recognized for advancements in electronic functionality, AI and robotics.

“MD Anderson has a significant opportunity and a responsibility to our many stakeholders to create a digital ecosystem that promotes collaboration and advances scientific discovery to enhance patient outcomes,” David Jaffray, the cancer center’s chief technology and digital officer, said in a 2021 news release.

“Through our ongoing focus on enabling the use of new technologies to place quantitative data in context for our researchers,” Jaffray added, “we foster cutting-edge oncology data science to inform our cancer discovery research and to accelerate translation of our research findings into benefits for cancer patients.”

Ahead of MD Anderson on the list are:

  1. Mayo Clinic in Rochester, Minnesota.
  2. Cleveland Clinic in Cleveland.
  3. Massachusetts General Hospital in Boston.
  4. Johns Hopkins Hospital in Baltimore.
  5. Mount Sinai Hospital in New York City.

Other Houston hospitals on the list are:

  • Houston Methodist Hospital, No. 11.
  • Baylor St. Luke’s Medical Center, No. 105.
  • Texas Children’s Hospital, No. 197.
  • Memorial Hermann-Texas Medical Center, No. 266.

Expert: How to best repurpose Houston’s infrastructure for a clean energy future

guest column

Houston, often dubbed the “Energy Capital of the World,” is at a pivotal moment in its history. Known for its vast oil and gas reserves, the city is now embracing a new role as a leader in the clean energy transition. This shift is not just about adopting new technologies but also about creatively repurposing existing infrastructure to support sustainable energy solutions.

Houston’s offshore oil wells, many of which are old or abandoned, present a significant opportunity for carbon capture. By repurposing these wells, we can sequester carbon dioxide, reducing greenhouse gas emissions and mitigating climate change. This approach not only utilizes existing infrastructure but also provides a cost-effective solution for carbon management. According to the Greater Houston Partnership, initiatives like these are crucial as Houston aims to lower its climate-changing greenhouse gas emissions. Exxon estimates that just their proposed CCS hub could capture and store 50 million metric tons of CO2 annually by 2030 and 100 million metric tons by 2040.

The proximity of abandoned offshore platforms to the coast makes them ideal candidates for renewable energy substations. These platforms can be transformed into hubs for wind, solar or tidal energy, facilitating the integration of renewable energy into the grid. This repurposing not only maximizes the use of existing structures but also minimizes environmental disruption.

Decommissioned pipelines, which are already in place, offer a ready-made solution for routing renewable energy cables. By using these existing rights of way, Houston can avoid disturbing additional seafloor and reduce the environmental impact of new cable installations. This strategy ensures a smoother transition to renewable energy infrastructure. The U.S. Energy Information Administration notes that Texas, including Houston, leads the nation in wind-generated electricity, highlighting the potential for further renewable energy development.

Onshore oil and gas facilities in Houston also hold potential for clean energy repurposing. Wells that were drilled but never used for oil or gas can be adapted for geological thermal energy storage. This process involves storing excess renewable energy in the form of heat, which can be retrieved when needed, providing a reliable and sustainable energy source. This innovative use of existing wells aligns with Houston’s broader energy transition strategy, which aims to leverage the city’s industrial expertise for a low-carbon future.

Once the land has been remediated, old and abandoned oil fields can be converted into solar farms. This transformation not only provides a new use for previously contaminated land but also contributes to the generation of clean, renewable energy. Solar farms on these sites can help meet Houston’s energy needs while supporting environmental restoration. The Environmental Protection Agency in recent years recognized Houston as the top city in the U.S. for green energy usage, with annual green power usage topping 1 billion kilowatt-hours in 2021.

Houston’s journey towards a clean energy future is a testament to the power of innovation and adaptability. By repurposing existing infrastructure, we can create a sustainable energy landscape that honors the city’s industrial past while paving the way for a greener tomorrow. These strategies highlight the potential for Houston to lead in the clean energy transition, setting an example for cities worldwide.

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Tershara Mathews is the national offshore wind lead at WSP.

This article originally ran on EnergyCapital.


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