Waymo will be off Houston roads Memorial Day weekend. Photo by Justin Sullivan/Getty Images

Waymo has suspended driverless car services in Houston and other major Texas cities, and in Atlanta, after one of its vehicles was stranded by flooding during heavy rains that will likely also hinder travel in a large swath of the U.S over the holiday weekend.

Severe thunderstorms with large hail and gusty winds were possible Friday, May 22 in Texas and other parts of the Southern and Central Plains, the National Weather Service said.

Forecasters warned of possible flash flooding along the Gulf Coast of Texas and Louisiana on Saturday, when rain and thunderstorms were expected across much of the central and eastern U.S.

The Waymo vehicle got stuck during a downpour in Atlanta on Wednesday that flooded streets and even part of a downtown highway. The vehicle was not occupied and was later recovered, the company said in a statement. At least one other Waymo vehicle was waylaid during the storm.

Waymo serves only the city of Atlanta in Georgia, and services Dallas, Houston, Austin, and San Antonio in Texas.

The company paused service in Texas “out of an abundance of caution for the forecasted severe weather,” the statement said.

Soon, you'll be able to cruise to your destination without a driver in Houston. Photo via Cruise/Facebook

Self-driving rideshare company cruises its robotaxies into Houston

look ma, no driver

Anew driverless ridehail service is coming to Houston: Cruise, the all-electric, driverless car company backed by GM, is expanding in Texas with launches in both Dallas and the Bayou City.

This follows an initial launch in Austin in 2022, their first city in Texas.

Cruise builds and operates driverless vehicles that you can call via an app, like any other ride hailing service. "But our vehicles show up without anyone else inside," they say.

The entire fleet is all-electric and the vehicles are equipped with a 360-view, with the ability to react to whatever they encounter on the road.

They test their vehicles using simulations, through millions of scenarios and virtual miles; they’ve also driven more than 4 million real miles, mostly in San Francisco.

They have not defined what the cost will be but according to The Verge, the rates in San Francisco vary depending on length of trip and time of day: "A customer taking a 1.3-mile trip would pay 90 cents per mile and 40 cents per minute, in addition to a $5 base fee and 1.5 percent city tax, for a total of $8.72." By comparison, an Uber ride for the same trip would cost at least $10.41.

The company was founded in 2013 and vehicles began to hit the road in 2022. They operate a total fleet of roughly 300 all-electric AVs, powered 100 percent by renewable energy. In addition to Austin, they operate in San Francisco and Phoenix, where they've completed 35,000 self-driving deliveries in a partnership with Walmart.

According to a statement from CEO Kyle Vogt, they'll begin supervised driving (with a safety driver behind the wheel) in Houston as they finetune their AI technology to understand the nuances and unique elements of the city, with Dallas to follow shortly after.

In a blog post, Vogt says their cars drive the speed limit and come to a complete stop at every stop sign. They respond to police sirens, flashing lights on fire trucks or ambulances, and stop signs that fold out of school buses.

They react to people on scooters, people using bike lanes, and cars driving on the wrong side of the road. "In short, they are designed to drive safely by obeying the law and driving in a humanlike way," he says. Actually, that sounds better than humans.

When vehicles encounter a situation where they aren’t 100 percent sure of what to do, they slow down or stop and pull over to the side of the road. This has caused some bumps in San Francisco where cars stopped and idled in the street for no apparent reason, delaying bus riders and disrupting the work of firefighters.

Photo via Cruise/Facebook

Some of the "bumps" have been comical, such as the 2022 incident in which a confused San Francisco police officer pulled a Cruise over, and then the Cruise drove away.

And as Reuters notes, autonomous vehicles have not rolled out as fast as anticipated, due to regulations, safety investigations, and arduous technology.

When Cruise first enters a city, they hire a mapping and data collection team to learn bike lanes, school zones, and major intersections. But most of the time, the vehicles will be carrying riders in the back seat, or completely empty and en route to another pickup.

The company partners with first responders, including police and fire departments, to ensure they’re ready and familiar with how to interact with the vehicles, engaging with those agencies before and after launch.

"Our guiding mission has always been to improve road safety, reduce emissions, and reduce congestion with our driverless ride-hail service in cities, which is where we’ll see the most significant positive impact the soonest," Vogt says. "Houston and Dallas are committed to reducing traffic deaths as part of their Vision Zero commitments, and we are excited to operate in and partner with these new communities in this shared mission."

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This article originally ran on CultureMap.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.