4 fast-growing Houston tech companies secure spots on Deloitte list

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These are the four fastest-growing tech companies in Houston, according to Deloitte. Photo by Shobeir Ansar/Getty Images

Deloitte’s annual North America Technology Fast 500 list includes four Houston companies this year — all boasting of significant growth.

For Houston, Direct Digital Holdings, Inc. took the highest-ranking spot at No. 101 (up from 108 previous year) with 1,184 percent growth. NatGas Hub LLC (No. 286, 407 percent growth), Liongard (No. 437, 246 percent growth), and Stratus Medical LLC (No. 483, 212 percent growth) also made the list, which is an annual ranking of the fastest-growing North American companies in technology, energy tech sectors, telecommunications, life sciences, media, and fintech.

"Houston continues to demonstrate its prowess in fostering growth and technological advancement and I’m incredibly proud to see some of our local companies making significant strides and earning their well-deserved spots on the 2024 Deloitte Technology Fast 500 list,” Houston managing partner at Deloitte Melinda Yee says in a news release.

Award winners were selected based on fiscal year revenue growth from 2019 to 2022.

The companies achieved revenue growth ranging from 201 percent to 153,625 percent over the three-year time frame with an average growth rate of 1,981 percent and a median growth rate of 460 percent, according to a news release. Texas accounts for 6 percent of the winning companies with 73 percent of the companies from Texas are in the software sector.

“These companies exemplify the entrepreneurial spirit and innovative mindset that define Houston's dynamic business ecosystem,” Yee adds.

In 2023, the Houston representation looked similar. Direct Digital Holdings again topped the Houston rankings at No. 108, with Liongard, NatGasHub.com, and P97 Networks also showing substantial growth. As a state, Texas had 30 companies that made the list of the 541 ranked. In 2022, just one Houston company was recognized, as at No. 372 Onit reported revenue increase of 369 percent.

Biopharmaceutical company TG Therapeutics, Inc. was the No.1 spot in 2024 with a growth rate of 153,625 percent from 2020 to 2023. See the full list here.
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Four Houston companies ranked on Deloitte's annual list, but none were able to crack the top 100. Photo via Getty Images

Annual report ranks 4 Houston tech companies on list of fasting growing businesses

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Deloitte just unveiled the fastest-growing technology companies in North America — and four businesses from Houston made the cut.

For the 29th year, 2023 Technology Fast 500 ranked top tech, media, telecommunications, life sciences, and energy technology companies based on fiscal year revenue growth from 2019 to 2022. While no Houston business was able to break into the top 100, four did make the cut for this year's list.

“It is great to see Houston represented alongside established technology hubs on this year’s Fast 500 list,” Amy Chronis, vice chair, US Energy and Chemicals Leader and Houston managing partner at Deloitte, says in a statement. “Houston is planting seeds for future innovation, and the companies named to this year’s list confirm our city’s value proposition as an innovative community. We look forward to this growth continuing in the future and extend our congratulations to this year’s Houston winners.”

The four Houston companies that make the 2023 list are:

  • Direct Digital Holdings at No. 108 with 1,325 percent growth
  • Liongard at No. 208 with 680 percent growth
  • NatGasHub.com at No. 356 with 364 percent growth
  • P97 Networks at No. 506 with 225 percent growth

Thirty Texas companies made the list of the 541 ranked, making it the fourth most concentrated hub on the list behind the Bay Area, Tri-State Area, and New England. The companies on the list reported a revenue growth ranging from 201 percent to 222,189 percent over the three-year time frame from 2019 to 2022. The average growth rate was 1,934 percent and a median growth rate of 497 percent.

“Each year, we look forward to reviewing the progress and innovations of our Technology Fast 500 winners," Paul Silverglate, vice chair, Deloitte LLP and U.S. technology sector leader, says in the release. "This year is especially celebratory as we expand the number of winners to better represent just how many companies are developing new ideas to progress our society and the world, especially during a slow economy. While software and services and life sciences continue to dominate the top 10, we are encouraged to see other categories making their mark."

Software dominated the industry breakdown with 57 percent of the companies working in that field. However, the top company for 2023 was Vir Biotechnology Inc., a life science company that developed a COVID-19 treatment. Vir was also the top company in 2022.

Last year, only one Houston company made the list. At No. 372 Onit reported a revenue increase of 369 percent. The company also made the 2021 list, along with Graylog and Enercross.

The 11 executives now will move on to national Entrepreneur Of The Year program. National winners will be named in November. Photos courtesy

Houston innovators recognized at annual regional entrepreneur competition

Meet the winners

Eleven Houston-based executives have been crowned regional winners in the Entrepreneur Of The Year program, run by professional services firm EY.

The 11 executives now will move on to national Entrepreneur Of The Year program. National winners will be named in November.

“Every year, we are completely blown away by the accomplishments of our Entrepreneur Of The Year Regional Award winners, and 2023 is no different,” AJ Jordan, director of the Entrepreneur Of The Year program for EY Americas, says in a news release. “They are change-makers and champions of business and community, and we are so proud to be honoring them. We can’t wait to see how these leaders will continue to improve lives and disrupt industries.”

Here are the 11 local winners from the program’s Gulf South region.

Steve Altemus, president and CEO of Intuitive Machines

Intuitive Machines, founded in 2013, is a publicly traded space exploration company. The company’s upcoming mission will send the first U.S. spacecraft to the moon since 1972 as well as the first-ever commercial lunar lander. Its Nova-C spacecraft will carry commercial and NASA payloads.

Earlier this year, a joint venture led by Intuitive Machines nabbed a contract valued at up to $719 million for work on NASA’s Joint Polar Satellite System. The company, which went public in February 2023, forecasts revenue of $174 million to $268 million this year.

“Steve’s visionary mindset and ability to assemble and inspire a talented team have been instrumental in our collective success,” the company says in a statement about the Entrepreneur Of The Year award. “He consistently fosters a culture of excellence, empowering our diverse group of engineers, scientists, and visionaries to pioneer groundbreaking solutions and deliver outstanding results.”

Gaurab Chakrabarti, co-founder and CEO of Solugen, and Sean Hunt, co-founder and CTO

Solugen, founded in 2016, makes and distributes specialty chemicals derived from feedstock. The startup is reportedly valued at more than $2 billion. To date, Solugen has raised $642.2 million, according to Crunchbase.

In naming Solugen one of the most innovative companies of 2022, Fast Company noted that the carbon-negative process embraced by Solugen and the startup’s “ability to sell flexible amounts of chemicals to companies looking to lower their own footprint have helped the company make inroads in a traditionally slow-moving industry.”

Daryl Dudum and Matthew Hadda, founders and co-CEOs of Specialty1 Partners

Specialty1 Partners, which launched in 2019, supplies business services to dental surgery practices. These services include HR, recruiting, payroll, accounting, operations, marketing, business development, compliance, IT, and legal.

In 2022, Specialty1 Partners appeared at No. 72 on the Inc. 5000 list with two-year revenue growth of 2,921 percent.

“Supporting our partners and helping them grow while continuing to build partnerships with industry-leading, innovative surgical specialists is what we focus on every day,” Dudum says in a 2022 news release. “It’s not just about growing our network — we are committed to helping our partner practices grow and succeed on their terms.”

Ludmila Golovine, president and CEO of MasterWord Services

MasterWord Services offers translation and interpretation in more than 400 languages for customers such as energy, health care, and tech companies. The woman-owned business was founded in 1993.

“I’m grateful to our exceptional team and to each of our translators and interpreters who every day live our mission of connecting people across language and culture,” Golovine says in a news release about the Entrepreneur Of The Year honor.

Roger Jenkins, president and CEO of Murphy Oil

Murphy Oil is involved in oil and natural gas exploration and production primarily onshore in the U.S. and Canada, and offshore along the Gulf of Mexico. The publicly traded Fortune 1000 company, founded in 1944, racked up revenue of nearly $4 billion in 2022.

“Over the years, the company has grown and evolved to become a leading independent energy company, with strategic assets around the world,” Murphy says on its website. “All the while, we have remained true to our mission — to challenge the norm, tap into our strong legacy, and use our foresight and financial discipline to deliver inspired energy solutions.

Mohammad Millwala, founder and CEO of DM Clinical Research

DM Clinical Research, founded in 2006, runs 13 sites for clinical trials. Its areas of specialty include vaccines, internal medicine, pediatrics, gastrointestinal, psychiatry, and women’s health.

“DM Clinical Research is in a period of rapid growth with multiple new study sites added over the last two years in addition to the quadrupling of our staff to over 500 employees,” Millwala says in a January 2023 news release. “We expect this transformational growth trajectory to continue for the foreseeable future, on the road to becoming the leading independent clinical research network in the nation.”

Mark Walker, co-founder, chairman and CEO of Direct Digital Holdings, and Keith Smith, co-founder and president

Publicly traded Direct Digital Holdings owns three operating companies that offer online platforms for advertising. Three years after its founding in 2018, the company became the ninth Black-owned business to go public in the U.S.

The company posted revenue of $88 million in 2022, up 131 percent from the previous year.

“Direct Digital Holdings’ success is rooted in the hard work and commitment we have long seen in taking advantage of advertising opportunities targeting underserved communities and [that] markets often overlook,” Smith says in a news release about the Entrepreneur Of The Year award.

Omair Tariq, co-founder and CEO of Cart.com

While technically headquartered in Austin, Houston-funded Cart.com's co-founder and CEO, Omair Tariq, also was a Gulf South winner in the Entrepreneur Of The Year program.

The e-commerce company moved its headquarters from Houston to Austin in 2021. However, Tariq remains in Houston. In May 2023, Tariq delivered the commencement address to MBA recipients from Rice University’s Jones Graduate School of Business, where he earned his MBA.

Cart.com, founded in 2020, offers software and services to thousands of online merchants. To date, the pre-IPO company has raised $421 million in funding, according to Crunchbase.

“We want to be the commerce-enablement infrastructure for the largest brands in the world,” Tariq told the Insider news website in 2022.

This week's roundup of Houston innovators includes Mark Walker of Direct Digital Holdings, Will Womble of Umbrage, and Steve Altemus of Intuitive Machines. Photos courtesy

3 Houston innovators to know this week

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Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from adtech to aerospace — recently making headlines in Houston innovation.

Mark Walker, CEO, co-founder and chairman of Direct Digital Holdings

This month, Mark Walker is celebrating his company's one year anniversary of going public — only the ninth Black-founded business to accomplish this feat on a U.S. stock exchange. Photo courtesy

Houston-based Direct Digital Holdings, an adtech platform, is celebrating one year after its IPO. Co-Founder Mark Walker shares on the Houston Innovators Platform how he took this experience in tech, advertising, and media to create his company's platform.

He also shared the story of how Direct Digital went public. Walker says the decision to IPO made the most sense for his company — though it wasn't an easy process. Direct Digital is only the ninth company founded by a Black entrepreneur to go public on a US stock exchange.

"If you think the process is hard — it actually is," Walker says on the journey to IPO. "We were a privately held company, and we knew we had a good growth trajectory and we looked a couple different options. We decided to go public in a very traditional way." Read more.

Steve Altemus, co-founder, president, and CEO of Intuitive Machines

Intuitive Machines listed on Nasdaq on February 14. Photo via intuitivemachines.com

Intuitive Machines, a space tech company based in Southeast Houston, announced that it has completed the transaction to merge with Inflection Point Acquisition Corp., a special purpose acquisition company traded on Nasdaq.

“We are excited to begin this new chapter as a publicly traded company,” says Steve Altemus, co-founder, president, and CEO of Intuitive Machines, in a news release. “Intuitive Machines is in a leading position to replace footprints with a foothold in the development of lunar space. With our launch into the public sphere through Inflection Point, we have reached new heights financially and opened the doors for even greater exploration and innovation for the progress of humanity.”

The transaction, which was originally announced in September, was approved by Inflection Point’s shareholders in a general meeting on February 8. As a result of the deal, the company will receive around $55 million of committed capital from an affiliate of its sponsor and company founders, the release states. Read more.

Will Womble, founder and CEO of Umbrage

Umbrage, a Houston-based developer of enterprise software, has been acquired. Photo via umbrage.com

Umbrage, founded in 2019, is proving once again that Space City is a software hub. Earlier this month, Founder Will Womble announced that Umbrage has been acquired by Bain & Company.

Umbrage creates custom software for companies by partnering with an internal technology team that makes the products. It’s a “teach a man to fish” method that has brought the company great success in creating software such as Shell’s TapUp app.

Bain & Company works with clients in 64 cities across 39 countries, meaning the global consultancy is positioned to bring Umbrage worldwide.

"Alongside Bain, we can deliver enhanced end-to-end solutions that will position our clients for success and to adapt during waves of disruptive emerging technologies," says CEO Womble in the release. Read more.

This month, Mark Walker is celebrating his company's one year anniversary of going public — only the ninth Black-founded business to accomplish this feat on a U.S. stock exchange. Photo courtesy

Houston founder shares how he's using tech to make digital media more effective and equitable

houston innovators podcast episode 173

After working in both sides of the advertising world, Mark Walker thought he could reimagine a platform that would be more efficient and equitable.

Walker co-founded his company, Direct Digital Holdings, an adtech platform, after serving in several roles — from an early hire at Houston digital media startup Questia to business development director at NRG Energy and COO of EBONY Media. He shares on the Houston Innovators Platform how he took this experience in tech, advertising, and media to create his company's platform.

"NRG Energy gave me a top-down view of the value chain, and Ebony gave me a bottoms-up view of the value chain of how media is purchased," Walker says on the show. "At Direct Digital Holdings, we help companies buy and sell media — and we leverage technology to do it. It's really the culmination of both of those experiences."

With over 30,000 publishers on its platform, Direct Digital makes it easier for its core customers — middle market companies looking to buy into the digital media ecosystem — to tap into these opportunities without the tech know-how they might otherwise need. Walker explains that at EBONY, he saw how small to midsize publications — especially the multicultural ones — were being left out on the ad selling side of the equation. The Direct Digital platform bridges the gap on each end.

Founded in 2018 in partnership with Keith Smith, who went through similar professional experiences, Direct Digital went public exactly one year ago after growing the company through strategic M&A activity. Walker says the decision to IPO made the most sense for his company — though it wasn't an easy process. Direct Digital is only the ninth company founded by a Black entrepreneur to go public on a US stock exchange.

"If you think the process is hard — it actually is," Walker says on the journey to IPO. "We were a privately held company, and we knew we had a good growth trajectory and we looked a couple different options. We decided to go public in a very traditional way."

Walker explains there were some risks involved, but the co-founders ultimately decided to shy away from adding in investors who might not have the same ideas for the company's future.

Direct Digital has been a Houston company from the star — despite the city not being home to a booming adtech ecosystem. Instead, Houston — with its collection of Fortune 500 companies and rich diversity — has allowed the business to stand out.

"If you look at and reflect on how our company has been built — from our board of directors to our leadership and management team — we're a majority minority organization all the way across the board," Walker says. "Diversity is very important to us. It's the lifeblood of our business — especially because we're serving publishers in those communities in big way. And moreso, we think you get the best product, thoughts, and ideas from a diverse workforce, and Houston fits right into that mold for us."

Walker shares more about his company's future, advice on IPO, and what all he's watching in adtech — from AI to streaming — on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


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Axiom Space launches semiconductor and astronaut training initiatives

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Axiom Space, a Houston-based commercial spaceflight and space infrastructure company, has launched initiatives in two very different spheres — semiconductors and astronaut training.

On the semiconductor front, Axiom has signed a memorandum of understanding with Japanese chemical company Resonac Corp. to collaborate on semiconductor R&D and manufacturing projects carried out in space. Among Resonac’s products are materials used in chip manufacturing.

Axiom said the deal “paves the way toward leveraging microgravity to advance next-generation chip technologies and accelerate the in-space manufacturing market.”

Under the agreement, Axiom and Resonac will explore the potential production of semiconductor materials and chip packaging in microgravity and low-Earth-orbit environments.

“The unique environment of space offers immense potential for advancing semiconductor materials, especially in crystal growth,” Masato Fukushima, Resonac’s chief technology officer, said in a news release.

The deal will also extend Resonac’s work with Axiom on the development of molding compounds that can reduce “soft errors” when semiconductor devices are exposed to space radiation.

“Our collaboration with Resonac underscores how Axiom Space is enabling global corporations from around the world to leverage space to drive manufacturing innovation across critical technology sectors such as semiconductors,” Axiom astronaut Koichi Wakata, the company’s chief technology officer, said.

In the astronaut training arena, Axiom has tapped Portuguese physiologist Emiliano Ventura as its first “Project Astronaut.” Ventura will apply his expertise in human performance to a pilot program aimed at testing six-month astronaut training protocols.

“His goal is to participate in a future mission and explore, with scientific depth and curiosity, how the human body adapts to microgravity, contributing fresh insights to the current body of research in space physiology,” Axiom said.

Ventura has helped several Axiom crewmembers with physiological needs before and after missions aboard the International Space Station.

Axiom said Ventura’s pilot program will study astronauts’ physiological responses to microgravity during spaceflight. The program eventually will benefit Axiom astronauts heading to the world’s first commercial space station, which is being built by Axiom.

Michael López-Alegria, Axiom’s chief astronaut, said he and the company’s two other astronauts will train with Ventura. The Project Astronaut initiative “strengthens our commitment to enabling safe, effective, and inspiring commercial space missions while supporting scientific objectives worldwide.” López-Alegria said.

Houston scientist launches new app to support mental health professionals

App for that

One Houston-based mental health scientist is launching a new app-based approach to continuing education that she hopes will change the way doctors, therapists, and social workers evolve in their field.

The app, MHNTI, is named for its parent company, the Mental Health Network & Training Institute. It's a one-stop shop for mental health professionals to find trainers, expert consultations, local providers, webinars, and other tools related to licensure certification and renewal.

Free and paid tiers offer different levels of access, but both offer doctors, counselors, and more an easier way to engage with continuing education. When a mental health professional is looking to expand their knowledge in a way that coincides with CE requirements, MHNTI provides it; as easy as using Amazon.

"We built MHNTI for the clinicians craving meaningful, ongoing training that fits real-life schedules," said Dr. Elizabeth McIngvale. "MHNTI is more than an app. It's a movement to support mental health professionals at every career stage."

McIngvale, the daughter of celebrated Houston entrepreneur Jim "Mattress Mack" McIngvale, co-founded MHNTI after becoming one of the leading experts on obsessive-compulsive disorder (OCD) in the United States. Born with the condition herself, she suffered greatly as a child to the point that she required extensive repetitive rituals daily just to function. She responded to exposure with response prevention (ERP) treatment, earned her Ph.D. from the University of Houston, and is now the director at the OCD Institute of Texas.

This is not the first time she used the internet to try to improve the mental health industry. In 2018, she launched the OCD Challenge website, a free resource for people with OCD.

McIngvale's co-founder is New York-based doctor, entrepreneur, and author Lauren Wadsworth, another expert in OCD and other anxiety disorders. Like McIngvale, she understands that the labyrinthian world of continuing education can keep mental health professionals from achieving their potential.

"Mental health providers are often overworked and under-resourced. MHNTI is here to change that," said Wadsworth. "We're creating a space where clinicians can continuously learn, grow, and feel supported by experts who understand the work firsthand."

MHNTI is available in the App Store, Google Play, and for desktop.

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A version of this article originally appeared on CultureMap.com.

Announcing the 2025 Houston Innovation Awards finalists

Inspirational Innovators

InnovationMap is proud to reveal the finalists for the 2025 Houston Innovation Awards.

Taking place on November 13 at Greentown Labs, the fifth annual Houston Innovation Awards will honor the best of Houston's innovation ecosystem, including startups, entrepreneurs, mentors, and more.

This year's finalists were determined by our esteemed panel of judges, comprised of past award winners and InnovationMap editorial leadership.

The panel reviewed nominee applications across 10 prestigious categories to determine our finalists. They will select the winner for each category, except for Startup of the Year, which will be chosen by the public via online voting launching later this month.

We'll announce our 2025 Trailblazer Award recipient in the coming weeks, and then we'll unveil the rest of this year's winners live at our awards ceremony.

Get to know all of our finalists in more detail through editorial spotlights leading up to the big event. Then, join us on November 13 as we unveil the winners and celebrate all things Houston innovation. Tickets are on sale now — secure yours today.

Without further ado, here are the 2025 Houston Innovation Awards finalists:

Minority-founded Business

Honoring an innovative startup founded or co-founded by BIPOC or LGBTQ+ representation:

  • Capwell Services
  • Deep Anchor Solutions
  • Mars Materials
  • Torres Orbital Mining (TOM)
  • Wellysis USA

Female-founded Business

Honoring an innovative startup founded or co-founded by a woman:

  • Anning Corporation
  • Bairitone Health
  • Brain Haven
  • FlowCare
  • March Biosciences
  • TrialClinIQ

Energy Transition Business

Honoring an innovative startup providing a solution within renewables, climatetech, clean energy, alternative materials, circular economy and beyond:

  • Anning Corporation
  • Capwell Services
  • Deep Anchor Solutions
  • Eclipse Energy
  • Loop Bioproducts
  • Mars Materials
  • Solidec

Health Tech Business

Honoring an innovative startup within the health and medical technology sectors:

  • Bairitone Health
  • Corveus Medical
  • FibroBiologics
  • Koda Health
  • NanoEar
  • Wellysis USA

Deep Tech Business

Honoring an innovative startup providing technology solutions based on substantial scientific or engineering challenges, including those in the AI, robotics and space sectors:

  • ARIX Technologies
  • Little Place Labs
  • Newfound Materials
  • Paladin Drones
  • Persona AI
  • Tempest Droneworx

Startup of the Year (People's Choice)

Honoring a startup celebrating a recent milestone or success. The winner will be selected by the community via an online voting experience:

  • Eclipse Energy
  • FlowCare
  • MyoStep
  • Persona AI
  • Rheom Materials
  • Solidec

Scaleup of the Year

Honoring an innovative later-stage startup that's recently reached a significant milestone in company growth:

  • Coya Therapeutics
  • Fervo Energy
  • Koda Health
  • Mati Carbon
  • Molecule
  • Utility Global

Incubator/Accelerator of the Year

Honoring a local incubator or accelerator that is championing and fueling the growth of Houston startups:

  • Activate
  • Energy Tech Nexus
  • Greentown Labs
  • Healthtech Accelerator (TMCi)
  • Impact Hub Houston

Mentor of the Year

Honoring an individual who dedicates their time and expertise to guide and support budding entrepreneurs. Presented by Houston Community College:

  • Anil Shetty, Inform AI
  • Jason Ethier, EnergyTech Nexus
  • Jeremy Pitts, Activate
  • Joe Alapat, Liongard
  • Neal Dikeman, Energy Transition Ventures
  • Nisha Desai, Intention

Trailblazer Recipient

  • To be announced
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Interested in sponsoring the 2025 Houston Innovation Awards? Contact sales@innovationmap.com for details.

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