4 fast-growing Houston tech companies secure spots on Deloitte list

big wins

These are the four fastest-growing tech companies in Houston, according to Deloitte. Photo by Shobeir Ansar/Getty Images

Deloitte’s annual North America Technology Fast 500 list includes four Houston companies this year — all boasting of significant growth.

For Houston, Direct Digital Holdings, Inc. took the highest-ranking spot at No. 101 (up from 108 previous year) with 1,184 percent growth. NatGas Hub LLC (No. 286, 407 percent growth), Liongard (No. 437, 246 percent growth), and Stratus Medical LLC (No. 483, 212 percent growth) also made the list, which is an annual ranking of the fastest-growing North American companies in technology, energy tech sectors, telecommunications, life sciences, media, and fintech.

"Houston continues to demonstrate its prowess in fostering growth and technological advancement and I’m incredibly proud to see some of our local companies making significant strides and earning their well-deserved spots on the 2024 Deloitte Technology Fast 500 list,” Houston managing partner at Deloitte Melinda Yee says in a news release.

Award winners were selected based on fiscal year revenue growth from 2019 to 2022.

The companies achieved revenue growth ranging from 201 percent to 153,625 percent over the three-year time frame with an average growth rate of 1,981 percent and a median growth rate of 460 percent, according to a news release. Texas accounts for 6 percent of the winning companies with 73 percent of the companies from Texas are in the software sector.

“These companies exemplify the entrepreneurial spirit and innovative mindset that define Houston's dynamic business ecosystem,” Yee adds.

In 2023, the Houston representation looked similar. Direct Digital Holdings again topped the Houston rankings at No. 108, with Liongard, NatGasHub.com, and P97 Networks also showing substantial growth. As a state, Texas had 30 companies that made the list of the 541 ranked. In 2022, just one Houston company was recognized, as at No. 372 Onit reported revenue increase of 369 percent.

Biopharmaceutical company TG Therapeutics, Inc. was the No.1 spot in 2024 with a growth rate of 153,625 percent from 2020 to 2023. See the full list here.
From Your Site Articles
Four Houston companies ranked on Deloitte's annual list, but none were able to crack the top 100. Photo via Getty Images

Annual report ranks 4 Houston tech companies on list of fasting growing businesses

trending up

Deloitte just unveiled the fastest-growing technology companies in North America — and four businesses from Houston made the cut.

For the 29th year, 2023 Technology Fast 500 ranked top tech, media, telecommunications, life sciences, and energy technology companies based on fiscal year revenue growth from 2019 to 2022. While no Houston business was able to break into the top 100, four did make the cut for this year's list.

“It is great to see Houston represented alongside established technology hubs on this year’s Fast 500 list,” Amy Chronis, vice chair, US Energy and Chemicals Leader and Houston managing partner at Deloitte, says in a statement. “Houston is planting seeds for future innovation, and the companies named to this year’s list confirm our city’s value proposition as an innovative community. We look forward to this growth continuing in the future and extend our congratulations to this year’s Houston winners.”

The four Houston companies that make the 2023 list are:

  • Direct Digital Holdings at No. 108 with 1,325 percent growth
  • Liongard at No. 208 with 680 percent growth
  • NatGasHub.com at No. 356 with 364 percent growth
  • P97 Networks at No. 506 with 225 percent growth

Thirty Texas companies made the list of the 541 ranked, making it the fourth most concentrated hub on the list behind the Bay Area, Tri-State Area, and New England. The companies on the list reported a revenue growth ranging from 201 percent to 222,189 percent over the three-year time frame from 2019 to 2022. The average growth rate was 1,934 percent and a median growth rate of 497 percent.

“Each year, we look forward to reviewing the progress and innovations of our Technology Fast 500 winners," Paul Silverglate, vice chair, Deloitte LLP and U.S. technology sector leader, says in the release. "This year is especially celebratory as we expand the number of winners to better represent just how many companies are developing new ideas to progress our society and the world, especially during a slow economy. While software and services and life sciences continue to dominate the top 10, we are encouraged to see other categories making their mark."

Software dominated the industry breakdown with 57 percent of the companies working in that field. However, the top company for 2023 was Vir Biotechnology Inc., a life science company that developed a COVID-19 treatment. Vir was also the top company in 2022.

Last year, only one Houston company made the list. At No. 372 Onit reported a revenue increase of 369 percent. The company also made the 2021 list, along with Graylog and Enercross.

The 11 executives now will move on to national Entrepreneur Of The Year program. National winners will be named in November. Photos courtesy

Houston innovators recognized at annual regional entrepreneur competition

Meet the winners

Eleven Houston-based executives have been crowned regional winners in the Entrepreneur Of The Year program, run by professional services firm EY.

The 11 executives now will move on to national Entrepreneur Of The Year program. National winners will be named in November.

“Every year, we are completely blown away by the accomplishments of our Entrepreneur Of The Year Regional Award winners, and 2023 is no different,” AJ Jordan, director of the Entrepreneur Of The Year program for EY Americas, says in a news release. “They are change-makers and champions of business and community, and we are so proud to be honoring them. We can’t wait to see how these leaders will continue to improve lives and disrupt industries.”

Here are the 11 local winners from the program’s Gulf South region.

Steve Altemus, president and CEO of Intuitive Machines

Intuitive Machines, founded in 2013, is a publicly traded space exploration company. The company’s upcoming mission will send the first U.S. spacecraft to the moon since 1972 as well as the first-ever commercial lunar lander. Its Nova-C spacecraft will carry commercial and NASA payloads.

Earlier this year, a joint venture led by Intuitive Machines nabbed a contract valued at up to $719 million for work on NASA’s Joint Polar Satellite System. The company, which went public in February 2023, forecasts revenue of $174 million to $268 million this year.

“Steve’s visionary mindset and ability to assemble and inspire a talented team have been instrumental in our collective success,” the company says in a statement about the Entrepreneur Of The Year award. “He consistently fosters a culture of excellence, empowering our diverse group of engineers, scientists, and visionaries to pioneer groundbreaking solutions and deliver outstanding results.”

Gaurab Chakrabarti, co-founder and CEO of Solugen, and Sean Hunt, co-founder and CTO

Solugen, founded in 2016, makes and distributes specialty chemicals derived from feedstock. The startup is reportedly valued at more than $2 billion. To date, Solugen has raised $642.2 million, according to Crunchbase.

In naming Solugen one of the most innovative companies of 2022, Fast Company noted that the carbon-negative process embraced by Solugen and the startup’s “ability to sell flexible amounts of chemicals to companies looking to lower their own footprint have helped the company make inroads in a traditionally slow-moving industry.”

Daryl Dudum and Matthew Hadda, founders and co-CEOs of Specialty1 Partners

Specialty1 Partners, which launched in 2019, supplies business services to dental surgery practices. These services include HR, recruiting, payroll, accounting, operations, marketing, business development, compliance, IT, and legal.

In 2022, Specialty1 Partners appeared at No. 72 on the Inc. 5000 list with two-year revenue growth of 2,921 percent.

“Supporting our partners and helping them grow while continuing to build partnerships with industry-leading, innovative surgical specialists is what we focus on every day,” Dudum says in a 2022 news release. “It’s not just about growing our network — we are committed to helping our partner practices grow and succeed on their terms.”

Ludmila Golovine, president and CEO of MasterWord Services

MasterWord Services offers translation and interpretation in more than 400 languages for customers such as energy, health care, and tech companies. The woman-owned business was founded in 1993.

“I’m grateful to our exceptional team and to each of our translators and interpreters who every day live our mission of connecting people across language and culture,” Golovine says in a news release about the Entrepreneur Of The Year honor.

Roger Jenkins, president and CEO of Murphy Oil

Murphy Oil is involved in oil and natural gas exploration and production primarily onshore in the U.S. and Canada, and offshore along the Gulf of Mexico. The publicly traded Fortune 1000 company, founded in 1944, racked up revenue of nearly $4 billion in 2022.

“Over the years, the company has grown and evolved to become a leading independent energy company, with strategic assets around the world,” Murphy says on its website. “All the while, we have remained true to our mission — to challenge the norm, tap into our strong legacy, and use our foresight and financial discipline to deliver inspired energy solutions.

Mohammad Millwala, founder and CEO of DM Clinical Research

DM Clinical Research, founded in 2006, runs 13 sites for clinical trials. Its areas of specialty include vaccines, internal medicine, pediatrics, gastrointestinal, psychiatry, and women’s health.

“DM Clinical Research is in a period of rapid growth with multiple new study sites added over the last two years in addition to the quadrupling of our staff to over 500 employees,” Millwala says in a January 2023 news release. “We expect this transformational growth trajectory to continue for the foreseeable future, on the road to becoming the leading independent clinical research network in the nation.”

Mark Walker, co-founder, chairman and CEO of Direct Digital Holdings, and Keith Smith, co-founder and president

Publicly traded Direct Digital Holdings owns three operating companies that offer online platforms for advertising. Three years after its founding in 2018, the company became the ninth Black-owned business to go public in the U.S.

The company posted revenue of $88 million in 2022, up 131 percent from the previous year.

“Direct Digital Holdings’ success is rooted in the hard work and commitment we have long seen in taking advantage of advertising opportunities targeting underserved communities and [that] markets often overlook,” Smith says in a news release about the Entrepreneur Of The Year award.

Omair Tariq, co-founder and CEO of Cart.com

While technically headquartered in Austin, Houston-funded Cart.com's co-founder and CEO, Omair Tariq, also was a Gulf South winner in the Entrepreneur Of The Year program.

The e-commerce company moved its headquarters from Houston to Austin in 2021. However, Tariq remains in Houston. In May 2023, Tariq delivered the commencement address to MBA recipients from Rice University’s Jones Graduate School of Business, where he earned his MBA.

Cart.com, founded in 2020, offers software and services to thousands of online merchants. To date, the pre-IPO company has raised $421 million in funding, according to Crunchbase.

“We want to be the commerce-enablement infrastructure for the largest brands in the world,” Tariq told the Insider news website in 2022.

This week's roundup of Houston innovators includes Mark Walker of Direct Digital Holdings, Will Womble of Umbrage, and Steve Altemus of Intuitive Machines. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from adtech to aerospace — recently making headlines in Houston innovation.

Mark Walker, CEO, co-founder and chairman of Direct Digital Holdings

This month, Mark Walker is celebrating his company's one year anniversary of going public — only the ninth Black-founded business to accomplish this feat on a U.S. stock exchange. Photo courtesy

Houston-based Direct Digital Holdings, an adtech platform, is celebrating one year after its IPO. Co-Founder Mark Walker shares on the Houston Innovators Platform how he took this experience in tech, advertising, and media to create his company's platform.

He also shared the story of how Direct Digital went public. Walker says the decision to IPO made the most sense for his company — though it wasn't an easy process. Direct Digital is only the ninth company founded by a Black entrepreneur to go public on a US stock exchange.

"If you think the process is hard — it actually is," Walker says on the journey to IPO. "We were a privately held company, and we knew we had a good growth trajectory and we looked a couple different options. We decided to go public in a very traditional way." Read more.

Steve Altemus, co-founder, president, and CEO of Intuitive Machines

Intuitive Machines listed on Nasdaq on February 14. Photo via intuitivemachines.com

Intuitive Machines, a space tech company based in Southeast Houston, announced that it has completed the transaction to merge with Inflection Point Acquisition Corp., a special purpose acquisition company traded on Nasdaq.

“We are excited to begin this new chapter as a publicly traded company,” says Steve Altemus, co-founder, president, and CEO of Intuitive Machines, in a news release. “Intuitive Machines is in a leading position to replace footprints with a foothold in the development of lunar space. With our launch into the public sphere through Inflection Point, we have reached new heights financially and opened the doors for even greater exploration and innovation for the progress of humanity.”

The transaction, which was originally announced in September, was approved by Inflection Point’s shareholders in a general meeting on February 8. As a result of the deal, the company will receive around $55 million of committed capital from an affiliate of its sponsor and company founders, the release states. Read more.

Will Womble, founder and CEO of Umbrage

Umbrage, a Houston-based developer of enterprise software, has been acquired. Photo via umbrage.com

Umbrage, founded in 2019, is proving once again that Space City is a software hub. Earlier this month, Founder Will Womble announced that Umbrage has been acquired by Bain & Company.

Umbrage creates custom software for companies by partnering with an internal technology team that makes the products. It’s a “teach a man to fish” method that has brought the company great success in creating software such as Shell’s TapUp app.

Bain & Company works with clients in 64 cities across 39 countries, meaning the global consultancy is positioned to bring Umbrage worldwide.

"Alongside Bain, we can deliver enhanced end-to-end solutions that will position our clients for success and to adapt during waves of disruptive emerging technologies," says CEO Womble in the release. Read more.

This month, Mark Walker is celebrating his company's one year anniversary of going public — only the ninth Black-founded business to accomplish this feat on a U.S. stock exchange. Photo courtesy

Houston founder shares how he's using tech to make digital media more effective and equitable

houston innovators podcast episode 173

After working in both sides of the advertising world, Mark Walker thought he could reimagine a platform that would be more efficient and equitable.

Walker co-founded his company, Direct Digital Holdings, an adtech platform, after serving in several roles — from an early hire at Houston digital media startup Questia to business development director at NRG Energy and COO of EBONY Media. He shares on the Houston Innovators Platform how he took this experience in tech, advertising, and media to create his company's platform.

"NRG Energy gave me a top-down view of the value chain, and Ebony gave me a bottoms-up view of the value chain of how media is purchased," Walker says on the show. "At Direct Digital Holdings, we help companies buy and sell media — and we leverage technology to do it. It's really the culmination of both of those experiences."

With over 30,000 publishers on its platform, Direct Digital makes it easier for its core customers — middle market companies looking to buy into the digital media ecosystem — to tap into these opportunities without the tech know-how they might otherwise need. Walker explains that at EBONY, he saw how small to midsize publications — especially the multicultural ones — were being left out on the ad selling side of the equation. The Direct Digital platform bridges the gap on each end.

Founded in 2018 in partnership with Keith Smith, who went through similar professional experiences, Direct Digital went public exactly one year ago after growing the company through strategic M&A activity. Walker says the decision to IPO made the most sense for his company — though it wasn't an easy process. Direct Digital is only the ninth company founded by a Black entrepreneur to go public on a US stock exchange.

"If you think the process is hard — it actually is," Walker says on the journey to IPO. "We were a privately held company, and we knew we had a good growth trajectory and we looked a couple different options. We decided to go public in a very traditional way."

Walker explains there were some risks involved, but the co-founders ultimately decided to shy away from adding in investors who might not have the same ideas for the company's future.

Direct Digital has been a Houston company from the star — despite the city not being home to a booming adtech ecosystem. Instead, Houston — with its collection of Fortune 500 companies and rich diversity — has allowed the business to stand out.

"If you look at and reflect on how our company has been built — from our board of directors to our leadership and management team — we're a majority minority organization all the way across the board," Walker says. "Diversity is very important to us. It's the lifeblood of our business — especially because we're serving publishers in those communities in big way. And moreso, we think you get the best product, thoughts, and ideas from a diverse workforce, and Houston fits right into that mold for us."

Walker shares more about his company's future, advice on IPO, and what all he's watching in adtech — from AI to streaming — on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Play it back: Houston home tech startup begins 2025 with fresh funding

HOUSTON INNOVATORS PODCAST EPISODE 272

One of the dozen or so Houston startups kicking of the new year with fresh funding is SmartAC.com, a company that's designed a platform that enables contractors in the HVAC and plumbing industries to monitor, manage, and optimize their maintenance memberships through advanced sensors, AI-driven diagnostics, and proactive alerts.

Last month, the SmartAC.com raised a follow-on round with support from local investor Mercury to continue growth and expansion of the product, which has evolved on many ways since the company launched in 2020, emerging from stealth with $10 million raised in a series A. In a May 2023 interview for the Houston Innovators Podcast, Founder and CEO Josh Teekell explained how he embraced the power of a pivot.

The company's sensors can monitor all aspects of air conditioning units and report back any issues, meaning homeowners have quicker and less costly repairs. While SmartAC.com started with providing the service and tech to homeowners directly, Teekell says he's had a greater interest in working with plumbers and HVAC companies who then deploy the technology to their customers.

"It became quite evident that homeowners don't care about air conditioning really at all until their system breaks," Teekell says on the show. "The technology is really built around giving those contractors as another way to gain a customer relationship and keep it."

Revisit the podcast episode below where Teekell talks about SmartAC.com's last raise.

SmartAC.com's previous round in 2023 — a $22 million series B — was used grow its team that goes out to deploy the technology and train the contractors on the platform.

"We've been very fortunate to get some of the biggest names in Houston on our cap table," Teekell says in the May 2023 conversation. "Since we're raising a bunch of money locally, everyone understands what a pain air conditioning can be."

Houston biotech company tests hard-to-fight cancer therapeutics

fighting cancer

A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.

Pioneering Houston biotech startup expands to Brazil for next phase

On the Move

Houston biotech company Cemvita has expanded into Brazil. The company officially established a new subsidiary in the country under the same name.

According to an announcement made earlier this month, the expansion aims to capitalize on Brazil’s progressive regulatory framework, including Brazil’s Fuel of the Future Law, which was enacted in 2024. The company said the expansion also aims to coincide with the 2025 COP30, the UN’s climate change conference, which will be hosted in Brazil in November.

Cemvita utilizes synthetic biology to transform carbon emissions into valuable bio-based chemicals.

“For decades Brazil has pioneered the bioeconomy, and now the time has come to create the future of the circular bioeconomy,” Moji Karimi, CEO of Cemvita, said in a news release. “Our vision is to combine the innovation Cemvita is known for with Brazil’s expertise and resources to create an ecosystem where waste becomes opportunity and sustainability drives growth. By joining forces with Brazilian partners, Cemvita aims to build on Brazil’s storied history in the bioeconomy while laying the groundwork for a circular and sustainable future.”

The Fuel of the Future Law mandates an increase in the biodiesel content of diesel fuel, starting from 15 percent in March and increasing to 20 percent by 2030. It also requires the adoption of Sustainable Aviation Fuel (SAF) and for domestic flights to reduce greenhouse gas emissions by 1 percent starting in 2027, growing to 10 percent reduction by 2037.

Cemvita agreed to a 20-year contract that specified it would supply up to 50 million gallons of SAF annually to United Airlines in 2023.

"This is all made possible by our innovative technology, which transforms carbon waste into value,” Marcio Da Silva, VP of Innovation, said in a news release. “Unlike traditional methods, it requires neither a large land footprint nor clean freshwater, ensuring minimal environmental impact. At the same time, it produces high-value green chemicals—such as sustainable oils and biofuels—without competing with the critical resources needed for food production."

In 2024, Cemvita became capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita quadrupled output at its Houston plant. The company had originally planned to reach this milestone in 2029.

---

This story originally appeared on our sister site, EnergyCapitalHTX.

View All Listings