This week's roundup of Houston innovators includes Ryan DuChanois of Solidec and Stephanie Campbell and Diana Murakhovskaya of The Artemis Fund. Photos courtesy

Editor's note: Welcome to another Monday edition of Innovators to Know. Today I'm introducing you to three Houstonians to read up about — three individuals behind recent innovation and startup news stories in Houston as reported by InnovationMap. Learn more about them and their recent news below by clicking on each article.

Ryan DuChanois, co-founder and CEO at Solidec

Ryan DuChanois pitched his company Solidec at CERAWeek, and took home a prize of $25,000. Photo via Solidec/LinkedIn

For the third year, the Greater Houston Partnership's Houston Energy Transition Institute hosted its startup pitch competition at CERAWeek by S&P Global. A dozen startups walked away with recognition — and three some with cash prizes.

Houston-based Solidec won the top prize for the TEX-E pitches. The company, which is working on a platform to produce chemicals from captured carbon, won first place and $25,000. Ryan DuChanois, co-founder and CEO, pitched at the event.

"This prize will help us scale up our technology from the lab at Rice University and ultimately fulfill our mission of capturing yesterday's emissions and generating tomorrow's fuels," the company writes in a post on LinkedIn. Read more.

Stephanie Campbell and Diana Murakhovskaya, co-founders and general partners of The Artemis Fund

Diana Murakhovskaya and Stephanie Campbell are co-founders of The Artemis Fund, a Houston-based, female founder-focused venture capital firm that just announced its $36 million fund II. Photo courtesy of Artemis

In 2019, Stephanie Campbell saw an opportunity in the market — investing in women-led startups, something that wasn't happening at the volume it should have been.

"When we looked around, we really wanted to solve the problem of why women only receive 2 percent of venture capital," Campbell says on the Houston Innovators Podcast.

As angel investors, Campbell and Diana Murakhovskaya, co-founders and general partners of The Artemis Fund, saw tons of promising women-led businesses. Read more.

Diana Murakhovskaya and Stephanie Campbell are co-founders of The Artemis Fund, a Houston-based, female founder-focused venture capital firm that just announced its $36 million fund II. Photo courtesy of Artemis

Houston VC leaders to empower female founders in fintech, commerce, and care with new $36M fund

HOUSTON INNOVATORS PODCAST EPISODE 228

In 2019, Stephanie Campbell saw an opportunity in the market — investing in women-led startups, something that wasn't happening at the volume it should have been.

"When we looked around, we really wanted to solve the problem of why women only receive 2 percent of venture capital," Campbell says on the Houston Innovators Podcast.

As angel investors, Campbell and Diana Murakhovskaya, co-founders and general partners of The Artemis Fund, saw tons of promising women-led businesses.

"We were finding these incredible female founders who we felt deserved capital to bring their innovations to the market because they're solving big markets and big problems But there was a disconnect in terms of their access and network," she continues.

The other issue, as Campbell explains, was that firms that did have a female-focused angle weren't leading these early-stage rounds. That's where Artemis comes in.

"Our goal was to be the leading firm for these overlooked, underserved markets that have the ability to deliver outsized returns," Campbell says.

Almost five years and around 20 investments later, The Artemis Fund has announced its second $36 million fund to continue to fund female-led upstarts with a tech solution within fintech, commerce, and care — the three pillars The Artemis Fund invests in.

"We really wanted to solve not just problems for women, which is a lot of what we do, but for families, small businesses, and immigrants, which is how we came around to these three verticals," Murakhovskaya says.

She goes on to explain that a significant percentage of adults are a part of the "sandwich generation" — caring not only for their own children, but for their aging parents. Innovations within caregiving can help this generation with their caregiving and maintain their role in the workforce. Additionally, over half the United States workforce is employed by small businesses, but these companies usually lack access to innovative technology.

"We're thinking about what founders are building in these industries to help these businesses thrive and leave these legacy assets to their children," Murakhovskaya says.

The Artemis Fund has announced that it's closed its second fund. Courtesy photos

Houston-based, female-focused VC closes $36M fund

fresh funding

A women-led venture capital group based in Houston has closed its second fund to continue its mission of supporting female-founded startups in fintech, commerce, and care.

The Artemis Fund announced its $36 million second fund this month. Co-founded in 2019 by General Partner Stephanie Campbell, General Partner Diana Murakhovskaya, and Venture Partner Leslie Goldman Tepper, the firm has invested in more than 20 female-led startups — with over 60 percent with Black, Latinx, or immigrant leadership.

"Many funds have come to market that focus on diverse founders. Few are also funding the technology to address key barriers faced by overlooked businesses, communities, and families in the U.S.," Artemis leadership writes in a news release.

"Artemis invests in the big personal, every day, economic problems that Silicon Valley doesn’t understand or know how to solve," the release continues. "We see massive opportunity in what many VCs will quickly write off as too small, too fragmented, and too hard to solve. If it keeps families and small business owners up at night, we are likely backing a company solving it."

Artemis Fund II includes support from limited partners Bank of America, Bank of Montreal, TIAA Nuveen’s Churchill Asset Management, Texas Capital Bank, Amazon, The Rockwell Fund, and Ballentine Partners.

“The Artemis Fund is not only breaking down barriers themselves, but they are also investing in companies looking to catalyze change," Hong Ogle, Houston president at Bank of America, says in the release. "Artemis keenly understands how to identify and support diverse entrepreneurs, which ultimately helps us toward achieving our goal to advance economic opportunity for all our communities."

The second fund has already made investments in five startups:

  • Alameda, California-based Hello Divorce, a tech-enabled guide to divorce with research, planning, therapy, and community support.
  • Gemist, based in Los Angeles, provides tech tools to jewelers.
  • West Palm Beach, Florida-based Max Retail, a platform to sell leftover inventory.
  • Payverse, headquartered in Sherman Oaks, California, is a cross border payment processor leveraging their modern processing platform.
  • New York-based Builder's Patch, a software platform that streamlines the process to finance the development and preservation of affordable multifamily housing for CRE lenders and developers.

If you feel like it's hard to find venture capitalists in Houston, you wouldn't be wrong, according to this Houston investor. Photo via Getty Images

Houston investor outlines how rare VCs are in Houston — and how to find them

guest column

As a venture capitalist and former startup founder living in Houston, I get asked a lot about the best way to find and connect with a venture capitalist in Houston. My usual advice is to start with a list, and reach out to everyone on that list. But no one has a comprehensive list. In fact, VCs are such a quiet bunch that I’ve yet to meet someone who personally knows everyone on this proverbial list.

So, I got together with a couple of VC friends of mine, and we put together our own Houston venture capitalist list.

There are, by our count, 11 active venture capital funds headquartered in Houston of any size and type, and outside of corporate venture capital and angel investors, there are 30 total venture capitalists running funds.

Houston has always been quite thin on the VC fund front. I’ve jokingly introduced myself for a while as “one of the 13 venture capitalists in Houston.”

Let’s put this scale in some brutal perspective. With 7.2 million people in the Greater Houston Metro Area, the odds of finding a partner level active venture capitalist in Houston is about 1 in 240,000, if you take a most expanded definition of venture capitalist that might come down to 1 in 100,000. We’re the fifth largest metropolitan area in the country with a tremendous economic engine; there is a ton of capital in Houston, but it’s residing in things like institutional fixed income and equities, real estate, wealth management, corporate, private equity, family office, energy and infrastructure Basically, mostly everywhere but in venture capital funds for tech startups.

By comparison, there are almost as many Fortune 500 CEOs in Houston — 24, by our count — as venture capitalists and fewer venture capitalists than Fortune 1000 CEOs, of which there are 43. That means running into a VC in the checkout line at HEB is about as rare as running into the CEO of CenterPoint, ConocoPhillips, or Academy. In fact, as there are 115 cities in the Greater Houston area, you are three times more likely to be a mayor in Greater Houston Area than a partner at an investor at a VC firm, and more likely to be a college or university president. While we’re at it, you’re 400 times more likely to be a lawyer, 250 times more likely to be a CPA, and over 650 times more likely to be a medical doctor.

Our 30 venture capitalists in the Greater Houston Area are spread across 20 firms and all major venture sectors and stages. Venture capitalist is defined for this list as a full time managing director or partner-level investment professional actively running a venture capital fund with limited partners, currently investing in new venture capital deals from their fund from seed to growth stage, and residing in the Greater Houston Metro area.

To get to 31 we added in a couple of people running venture set asides for PE funds, and a number who work from Houston for funds with no office here. We excluded CVCs, as the decision making is more corporate than individual and rarely includes the committed fund and carried interest structure that defines venture capital, and excluded professionals at angel networks, accelerators, and seed funds that provide investment, but don’t manage conventional venture capital funds, as well as PE funds that do the occasional venture deal. We might be able to triple the number if we include venture capitalists at any professional level, and add in those professionals at PE and angel and seed funds, and corporate venture capital teams who are actively investing. But we’ll get to those other sources of funding in the next list.

The 11 venture capital funds headquartered in Houston are: Mercury, Energy Transition Ventures (my fund), Montrose Lane (formerly called Cottonwood), Texas Medical Center Venture Fund, Artemis, New Climate Ventures, Fitz Gate Ventures, Curate Capital, Knightsgate Ventures, Amplo Ventures,and First Bight Ventures.

Another half a dozen firms have a partner level venture capital investor here, but are headquartered elsewhere: Energy Innovation Capital, Decarbonization Partners, 1984 Ventures, Altitude Ventures, Ascension Ventures, Moneta Ventures, and MKB & Co. Two others, CSL Ventures and SCF Partners, are local private equity funds with a venture capital partner in Houston and a dedicated allocation from a PE fund.

Culling these for partner or managing director level currently in Houston, in alphabetical order by first name, LinkedIn profile and all.

We may have missed a couple of VCs hiding in plain sight, as venture capital is a pretty dynamic business.

VCs are just rare. And yes, perhaps more rare in Houston than in California. Something less than 1 in 100 VCs in the country live in Houston. Across the US there are somewhere around 1,000 to 2,000 active venture capital firms, and maybe another 1,000 to 2,000 active US based CVCs — so, plus or minus maybe at most 4,000 to 5,000 currently active partner level venture capitalists in the country excluding CVC professionals (active VCs and VC funds are really hard to count).

Perhaps in the most stunning statistic, the 7,386 elected state legislators in the US today outnumber the total number of American venture capitalists. Luckily for startup founders, the venture capitalists are more likely to return your phone call.

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Neal Dikeman is a venture capitalist and seven-time startup co-founder investing out of Energy Transition Ventures. He’s currently hosting the Venture Capital for First Time Founders Series at the Ion, where ETV is headquartered.

Meet five of the many Houston innovators that will be out at SXSW Pitch, Houston House, Founded in Texas, and much more this week and into next week. Photos courtesy

5 Houston innovators headed to SXSW to know this weekend

who's who

Editor's note: It's a special Friday edition of innovators to know this week — well, weekend. SXSW kicks off today and Houstonians will be headed up to Austin for the week or just the weekend. If you're looking out for the best panels and talks to go to, look no further than this guide I created — as well as the five Houston innovators I think you should know who are listed below.

Lara Cottingham, chief of staff for Greentown Labs

Photo via LinkedIn

Calling all energy transition startups, investors, and more. The Greater Houston Partnership is hosting a full day of energy transition discussions at Houston House on Monday, March 14, at the Line Hotel. Lara Cottingham of Greentown Labs will be at the activation site with a must-attend networking hour at 4 pm called Transition on Tap.

Diana Murakhovskaya, co-founder and general partner of The Artemis Fund

Photo via LinkedIn

Who runs the world? Women. And Diana Murakhovskaya knows that based off her work with her Houston-based venture capital fund, The Artemis Fund. Project W, Artemis Fund, HearstLab, and Beam have teamed up at SXSW to present the second Founded in Texas event on Sunday, March 13, at Relay Coworking. Twelve founders selected by application will pitch to investors from across the country . The audience will get a glimpse of the innovation and creativity at work in the growing Texas startup ecosystem.

Pamela Singh, co-founder and CEO of CaseCTRL

Photo courtesy of CaseCTRL

Pamela Singh is the only Houston startup founder to pitch this year at SXSW's pitch competition. Representing her digital health startup, Case CTRL, Singh takes the prestigious stage Saturday, March 12, to compete in the Enterprise & Smart Data Technology category.

Sandy Guitar, managing director of HX Venture Fund

Photo courtesy of Sandy Guitar

The HX Venture Fund is hosting a meetup that all of the Houston startup ecosystem needs to know about. Network with a number of founders from Houston's fastest-growing startups along with several great VCs around the nation to participate in a joint conversation about founding tech startups. The event will take place at 11:30 am to 12:30 pm at Hilton Austin Downtown, Room 408.

Ashley DeWalt, managing director of DivInc

Photo courtesy of DivInc

Ashley DeWalt, managing director of DivInc, is just one of the many Houston innovators featured in Houston House from the GHP. The activation starts Sunday, March 13, at the Line Hotel with a day of programming across industries and topics — from sports tech and diversity (both topics DeWalt specializes in) to health care innovation and space. Catch DeWalt's panel, Game Changers - The Rise of Sports Tech, on Sunday at 11:30 am at Houston House.

Looking into venture capital deal growth, new coworking coming to town, and more Houston innovation news. Getty Images

Houston's spike in VC deals, accelerator acquired, new coworking, and more innovation news

Short stories

Houston has seen some big headlines this month when it comes to innovation news — and you could have missed something.

From a report on venture capital funding last year and new coworking coming to town to a Houston investor selling her accelerator company, here's the latest batch of short stories in Houston innovation.

Houston sees spike in venture capital deals in 2019

Houston saw more venture capital funding in 2019 compared to 2018. Chart via crunchbase.com

Overall, 2019 was a good one for Texas venture capital deals. Austin had a record turnout of money invested in startups. Austin companies raised over $1.8 billion, which put the state capitol in the top 10 cities based on money raised, according to a report by Crunchbase.

And this Texas VC roundup on Crunchbase focused a lot of the Austin funding and didn't harp too much on the other Texas cities. But Houston's numbers are also record breaking. The Bayou City raised nearly $400 million last year — with the bulk of that being recorded in Q2 of 2019.

Houston's recorded $399.6 million in VC deals surpasses 2018's recorded funding by almost $20 million, but if you look at PitchBook and the National Venture Capital Association's data, the amount is higher. According to Pitchbook, the total funding raised in 2019 in Houston deals surprasses $600 million across 98 deals.

Houston investor-founded accelerator acquired

Houston investor ​Diana Murakhovskaya has sold her New York-based accelerator program. ​Photo courtesy of The Artemis Fund

New York-based Monarq Incubator, a venture capital-focused accelerator program for women, has been acquired by Female Founders Alliance. Monarq was co-founded by Diana Murakhovskaya, one of the three co-founders of Houston-based, female-focused The Artemis Fund.

Since its founding in 2017, Monarq accelerated 32 companies that have then gone on to raise more than $10 million in venture capital. The combined company, according to a news release, now represents the largest network of women and non-binary venture-scalable founders.

"FFA and Monarq share more than just a mission – we share founder DNA," says Leslie Feinzaig, CEO of Female Founders Alliance, in the release. "Our two communities and accelerator programs were built by women founders, for women founders. We are uniquely able to build programming that accelerates the success of women in our space, and now along with founder cred, we have scale and a national footprint. I am so excited for what we can achieve in this next stage of FFA."

The acquisition means a heightened focus on The Artemis Fund for Murakhovskaya.

"Now that I am full time focused on raising and investing with Artemis, it's great to know that our community and founders will have a home and provide us with a great source of deal flow," she says in an email to InnovationMap.

A new coworking company to enter Houston with Galleria-area office

New Galleria-area coworking is coming later this year. Photo via serendipitylabs.com

Serendipity Labs Coworking, which has over 100 coworking spaces across the United States and United Kingdom, announced its plans to enter six new markets this year. Houston is among the new locations for the coworking company.

Expected top open in the fall, the Houston coworking space will be a 28,331-square-foot space on the 20th floor of the Marathon Oil Tower at 5555 San Felipe St. in the Galleria area. According to the release, Cameron Coworking, a division of Cameron Management, will be the development partner for the Houston market.

"By partnering with asset owners of office, retail and residential buildings and then managing the Labs, we bring our operational expertise and marketing power, and we assure the upscale service standards of one of the top national flexible workplace networks will be met at every location," says John Arenas, chairman and CEO of Serendipity Labs, in a news release.

MassChallenge Texas opens applications for second cohort

Applications are open for MassChallenge Texas' second Houston cohort. Courtesy of MassChallenge

At an event on January 29 in both Houston and Austin, MassChallenge Texas opened applications for its 2020 cohorts

The 4-month accelerator program is set to begin in June and online applications close March 9. Prizes include six months of free office space and up to $250,000 in equity free investment. Click here for more information.

Houston entrepreneur named to 2020 class of Presidential Leadership Scholars

Houston startup founder, Reda Hicks, has been named a Presidential Leadership Scholar. Photo via presidentialleadershipscholars.org

For this sixth year, the Presidential Leadership Scholars announced its class of veterans, educators, physicians, public servants, and corporate professionals to participate in the program. Reda Hicks, founder of GotSpot was named as one of the 60 scholars. The program began this week in Washington D.C..

"I cannot wait to work with, and learn from, these exceptional leaders," Hicks shares on LinkedIn. "And through the program, I will be working on RescueSpot, a community resiliency application of GotSpot Inc."

Another Houstonian was selected too — Ganesh Betanabhatla, who is the managing partner and chief investment officer at Ramas Capital Management.

Ion Smart Cities Accelerator opens applications for second cohort

Aatonomy, a member of the first cohort, walked away with a cash prize at Demo Day. F. Carter Smith/Station Houston

The second cohort for the Ion Smart Cities Accelerator Program has opened applications online. The first cohort, focused on resilience and mobility, is currently in pilot mode. Cohort II will be focused on water purification/quality, air quality, and clean technology.

The applications will close on Monday, February 17, and startups that are selected will be notified the week of March 2.

The program, which was announced in June, is backed by Microsoft and Intel and named its first cohort last fall. The demo day for the first cohort took place last month. The accelerator has its own space and prototyping lab in downtown Houston, which opened in September.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.