3 Houston innovators to know this week

who's who

This week's innovators to know are Debbie Mercer, Andrew Bruce, and Maria Maso. Courtesy photos

While headlines about coronavirus keep multiplying — similar to the virus' cases, Houston's innovation news hasn't yet slowed.

This week's people to know include a female entrepreneur who's leveling the playing field for outdoorsy women, a blockchain expert with new growth, and an investor creating the angel network she's been wanting for years.

Debbie Mercer, founder of Zip Hers

Photo courtesy of Zip Hers

Debbie Mercer, a Houston entrepreneur, has designed articles of clothing to empower female athletes. The marathon runner was tired of seeing female runners standing in long lines, awaiting their turns to do their business behind closed doors, while their male friends resorted to quickly and discreetly ducking behind the porta-potties, or finding nearby trees. Precious time ticked by as the women watched their male counterparts continue the race.

The Houstonian created Zip Hers, an activewear brand that has a full-length zipper lining the bikini area of each pant, to accommodate on-the-go women. The Zip Hers concept and design was intended to level the playing field for women and men when it comes to competitive sports.

"If we're wasting time on a bathroom break and they're not, that holds us back…Maybe it's our little tiny contribution to women's equality. We just really want to help women be the best that they can be," Mercer says. Click here to read more.

Andrew Bruce, CEO and founder of Data Gumbo Corp.

Photo courtesy of Data Gumbo

For the fist time, Data Gumbo Corp.'s GumboNet will be used in geothermal energy drilling thanks to the startup's new Indonesia-based client, Air Drilling Associates, a drilling and project management service provider.

"Expansion into Southeast Asia with ADA's deployment signals GumboNet's global applicability and benefit to industry — in this case, geothermal energy development," says Andrew Bruce, CEO and founder of Data Gumbo, in a news release. "We are excited that Data Gumbo is entering yet another sector of the energy market for improvements across its supply chain." Click here to read more.

Maria Maso, founder of Business Angel Minority Association

Photo courtesy of Nijalon Dunn

Maria Maso, frustrated with her investment opportunities in Houston, has launched the Business Angel Minority Association, or baMa, to gather established or brand new angel investors to move the needle on investments into minority-founded startups. Maso, founder and CEO, and Garaizar, president, want to round up 100 investors by the end of 2020. And they want these investors to write checks.

"We are not a networking organization. We are an investment organization. We are expecting at some point that you are writing a check to a startup," Maso says. "If we are doing our job properly and we are showing you the right startups, you should be able to make a check at some point." Click here to read more.

Debbie Mercer, a Houston entrepreneur, has designed articles of clothing to empower female athletes. Photo courtesy of Zip Hers

Houston entrepreneur levels the playing field for female runners with new activewear line

running game

It was race day for avid marathon runner, Debbie Mercer. She and her race pack got up early on a brisk winter's day in Chicago, Illinois, piling on warm layers over their compression tights, to run the Chicago Marathon.

Miles into the race, Mercer and her friends made a pit stop at the portable bathrooms. The female runners stood in long lines, awaiting their turns to do their business behind closed doors, while their male friends resorted to quickly and discreetly ducking behind the porta-potties, or finding nearby trees. Precious time ticked by as the women watched their male counterparts continue the race.

"I remember thinking 'I wish there was some way that we could do that too,'" Mercer recalls.

The Houstonian created Zip Hers, an activewear brand that has a full-length zipper lining the bikini area of each pant, to accommodate on-the-go women. The Zip Hers concept and design was intended to level the playing field for women and men when it comes to competitive sports.

"If we're wasting time on a bathroom break and they're not, that holds us back…Maybe it's our little tiny contribution to women's equality. We just really want to help women be the best that they can be," Mercer says.

From full-length pants and tights, to 3-inch compression or loose shorts, Zip Hers has established an array of products suitable active women. However, it was a long and winding road to producing such innovative, high-quality products that could be competitive in such a vast industry of activewear, according to Mercer.

Zip Hers in the making

Photo courtesy of Zip Hers

Mercer kicked off prototype production in 2016. She jumped around to various designers and manufacturers, turning away samples that didn't quite fit her vision for the product. Part of the challenge, Mercer describes, was finding a manufacturer who could manipulate stretch and non-stretch fabric in high-quality ways. Maintaining maximum comfort and a sleek design were challenges when the new variable of a zipper was thrown into the mix.

"It took us a while to get the zipper design perfect so that it would fit well and have a design that was comfortable," Mercer says. "We had to find the right manufacturer to find the skill to make these. We found one in Dallas and one in Houston."

Through trial and error, the Zip Hers design team produced a smooth design that coexists seamlessly with the delicate areas that sit around the zipper. They created a custom-made zipper pull, an invisible, thin disk embossed with the Zip Hers logo.

"Women can easily grab it when they're squatting, and don't have to struggle to find it… you can't even tell that a zipper is there. It's very sleek," Mercer says. "They're all handmade. We have to have special fabric for the panels and…have to have special machines to get the seams just right."

By September 2019, the Zip Hers prototype was finalized and officially launched via the company's online retail site.

Game changers

Photo courtesy of Zip Hers

Zip Hers products, the first of their kind, are sure to change the game for female marathon runners, hikers and any other outdoor activity fanatics, Mercer says. With so many athletic brands available on the internet, Mercer hopes that Zip Hers' innovative approach to active wear, and the unique opportunity they offer to women, will help set the brand apart.

"We really don't see any other products out there like ours…As far as apparel goes, we're the only one," Mercer says.

Since launching last year, Zip Hers has watched their clientele expand with predominantly long distance runners and adventure goers. With the 'athleisure' trend on the rise, they're also seeing more women buying leisurewear for yoga classes, or indoor casual use. Mercer says that she hopes Zip Hers will continue to expand to reach female fishers, hunters, climbers, and even first responders, so that women never have to take off their duty belts.

From various race-day experiences of waiting in long bathroom lines as precious time ticks by, to when nature calls during outdoor activities involving co-ed company, Mercer confronted women's realities by proposing an empowering solution for women.

"Ultimately, it gives women a choice. What's more empowering for women than the power to choose what's best for them?" Mercer says.

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How a Houston company is fighting anxiety, insomnia & Alzheimer’s through waveforms

mental health

A Houston-based company is taking a medicine-free approach to target brain neurologically associated with mental illness.

Nexalin Technology’s patented, FDA-cleared frequency-based waveform targets key centers of the midbrain to support the normalization of neurochemicals through a process known as Transcranial Alternating Current Stimulation (tACS). Delivered via a non-invasive device, the treatment gently stimulates the hypothalamus and midbrain, helping to “reset networks associated with symptoms” of anxiety and insomnia. Early clinical evidence suggests this approach can promote healthier brain function and improved sleep.

Through its recently appointed scientific advisory board (SAB), Nexalin also aims to target Alzheimer’s disease with a clinical development pipeline supported by published data and internal data from studies involving its proprietary DIFS technology. Nexalin’s Gen-2 SYNC and Gen-3 Halo headset delivers the DIFS, which is a waveform that can penetrate deep brain structures implicated in cognitive decline and mental illness.

The board includes experts in neurology, neuroimaging and neurodegenerative diseases with Dr. Mingxiong Huang, Dr. David Owens, and Dr. Abe Scheer coming on board. Nexalin plans to initiate new Alzheimer’s-focused clinical studies in the Q3 2025 by incorporating cognitive testing, imaging biomarkers, and guided metrics to assess treatment efficacy and neural activation.

“I am excited to work alongside Nexalin’s leadership and fellow SAB members to help guide the next generation of non-invasive neuromodulation therapies,” Huang said in a news release. “The intersection of neuroimaging, brain stimulation, and clinical science holds enormous potential for treating neurodegenerative disease.”

Recently, Nexalin’s proprietary neurostimulation device moved forward with a clinical trial that evaluated its treatment of anxiety disorders and chronic insomnia in Brazil. The first of Nexalin’s Gen-2 15-milliamp neurostimulation devices was shipped to São Paulo, Brazil, and the study will be conducted at the Instituto de Psiquiatria University Hospital (IPq-HCFMUSP). The shipments aim to support the launch of a Phase II clinical trial in adult patients suffering from anxiety and insomnia. The Nexalin Gen-2 15-milliamp neurostimulation device has also been approved in China, Brazil and Oman. Its Gen 1 device first received FDA clearance in 2003, according to the company's website.

The company also enrolled the first patients in its clinical trial at the University of California, San Diego, in collaboration with the VA San Diego Healthcare System for its Nexalin HALO, which looks to treat mild traumatic brain injury and post-traumatic stress disorder in military personnel and the civilian population.

Nexalin previously raised $5 million through a

public stock offering.

Houston innovation hub announces first cohort for energy-focused accelerator

Powering Up

Energytech Nexus, a Houston-based hub for energy startups, has named its inaugural cohort of 14 companies for the new COPILOT accelerator.

COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. The Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory backs the COPILOT accelerator.

The eight-month COPILOT program offers mentorship, training and networking for startups. Program participants will be tasked with developing pilot projects for their innovations.

Two Houston startups are members of the first COPILOT class:

  • GeoFuels, housed at Houston’s Greentown Labs, has come up with a novel approach to hydrogen production that relies on geothermal power and methane decomposition.
  • PolyQor, which converts plastic waste into eco-friendly construction materials. Its flagship EcoGrete product is an additive for concrete that enhances its properties while reducing carbon emissions. PolyQor’s headquarters is at Houston’s Greentown Labs.

Other members of the COPILOT cohort are:

  • Birmingham, Alabama-based Accelerate Wind, developer of a wind turbine for commercial buildings.
  • Ann Arbor, Michigan-based Aquora Biosystems, which specializes in organic waste biorefineries.
  • Phoenix-based EarthEn Energy, a developer of technology for thermo-mechanical energy storage.
  • New York City-based Electromaim, which installs small hydro-generators in buildings’ water systems.
  • Chandler, Arizona-based EnKoat, an advanced materials company whose flagship product, the IntelliKoat System, is a patented two-layer thermal and weather barrier roof coating for flat and low-slope commercial buildings.
  • Calgary, Canada-based Harber Coatings, which manufactures electroless nickel coating and electroless nickel plating.
  • Dallas-based Janta Power, which designs and makes 3D solar towers.
  • Miami-based NanoSieve, a developer of gas remediation technology.
  • Palo Alto, California-based Popper Power, which has developed a platform that turns streetlight networks into resilient, maintenance-free distributed charging infrastructure.
  • Buffalo, New York-based Siva Powers America, developer of small wind turbines for farms, utility companies and others with annual energy needs of 300,000 to 2 million kilowatt-hours.
  • Los Angeles-based Thermoshade, which specializes in cooling panels for outdoor environments.
  • Waukesha, Wisconsin-based V-Glass, Inc., developer of a vacuum-insulated glass for affordable high-efficiency windows.

“These startups reflect the future of energy access and resilience innovation,” said Juliana Garaizar, founding partner of Energytech Nexus. “By connecting them directly with partners through COPILOT, we’re helping them overcome the ‘pilot gap’ to build solutions that scale.”

The startups will run pilot projects along the Gulf Coast for their inventions.

Rice University's top innovation exec leaving for new role at UVA

moving on

Paul Cherukuri, Rice University's top innovation executive, responsible for some of Rice’s major innovative projects like the Rice BioTech LaunchPad and Rice Nexus, will leave the university next month to accept a position at the University of Virginia.

Cherukuri, Rice’s first vice president for innovation and chief innovation officer, will become the University of Virginia’s Donna and Richard Tadler University Professor of Entrepreneurship and the school's first chief innovation officer, according to a release from Rice. Cherukuri, who has served for more than 10 years at Rice, plans to depart his current position on Sept. 30.

Adrian Trömel, associate vice president for innovation strategy and investments at Rice, will serve as interim vice president for innovation and chief innovation officer after Cherukuri departs, and as the university starts an international search for his replacement.

“We appointed Paul to build an ambitious and high-functioning innovation operation, and he has succeeded remarkably in short order,” Rice President Reginald DesRoches said in the release. “In every area, from technology translation and startup creation to commercialization and entrepreneurship training, he has led the effort to vastly improve our structure, operations and relationships. He has contributed immensely both to our strategies and their implementation across numerous areas, and we’ll miss him greatly.”

Cherukuri is a physicist, chemist and medical technology entrepreneur, and has been a member of DesRoches’ leadership team since 2022. Cherukuri served as executive director of Rice’s Institute of Biosciences and Bioengineering from 2016 to 2022, where he helped in the development of interdisciplinary translational research partnerships with federal and corporate agencies. His work helped earn nearly $37 million in funding for accelerating the development of new technologies into commercial products. In the energy transition field, Cherukuri led a $12.5 million partnership with Woodside Energy to transform greenhouse gases into advanced nanomaterials for next-generation batteries and transistors.

Initiatives the Rice Biotech Launch Pad, an accelerator focused on expediting the translation of the university’s health and medical technology; RBL LLC, a biotech venture studio in the Texas Medical Center’s Helix Park dedicated to commercializing lifesaving medical technologies from the Launch Pad; and Rice Nexus, an AI-focused "innovation factory" at the Ion; were all launched under Cherukuri’s leadership. With his work at the Ion, Cherukuri also led the announcement of a partnership with North America’s largest climate tech incubator, Greentown Labs.

“I am proud of the relentless innovative spirit we have built for Rice in Houston and around the world,” Cherukuri said in the release. “I look forward to bringing new energy and vision to UVA’s efforts in this critical space for our country, its success and future.”

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