This week's innovators to know are Debbie Mercer, Andrew Bruce, and Maria Maso. Courtesy photos

While headlines about coronavirus keep multiplying — similar to the virus' cases, Houston's innovation news hasn't yet slowed.

This week's people to know include a female entrepreneur who's leveling the playing field for outdoorsy women, a blockchain expert with new growth, and an investor creating the angel network she's been wanting for years.

Debbie Mercer, founder of Zip Hers

Photo courtesy of Zip Hers

Debbie Mercer, a Houston entrepreneur, has designed articles of clothing to empower female athletes. The marathon runner was tired of seeing female runners standing in long lines, awaiting their turns to do their business behind closed doors, while their male friends resorted to quickly and discreetly ducking behind the porta-potties, or finding nearby trees. Precious time ticked by as the women watched their male counterparts continue the race.

The Houstonian created Zip Hers, an activewear brand that has a full-length zipper lining the bikini area of each pant, to accommodate on-the-go women. The Zip Hers concept and design was intended to level the playing field for women and men when it comes to competitive sports.

"If we're wasting time on a bathroom break and they're not, that holds us back…Maybe it's our little tiny contribution to women's equality. We just really want to help women be the best that they can be," Mercer says. Click here to read more.

Andrew Bruce, CEO and founder of Data Gumbo Corp.

Photo courtesy of Data Gumbo

For the fist time, Data Gumbo Corp.'s GumboNet will be used in geothermal energy drilling thanks to the startup's new Indonesia-based client, Air Drilling Associates, a drilling and project management service provider.

"Expansion into Southeast Asia with ADA's deployment signals GumboNet's global applicability and benefit to industry — in this case, geothermal energy development," says Andrew Bruce, CEO and founder of Data Gumbo, in a news release. "We are excited that Data Gumbo is entering yet another sector of the energy market for improvements across its supply chain." Click here to read more.

Maria Maso, founder of Business Angel Minority Association

Photo courtesy of Nijalon Dunn

Maria Maso, frustrated with her investment opportunities in Houston, has launched the Business Angel Minority Association, or baMa, to gather established or brand new angel investors to move the needle on investments into minority-founded startups. Maso, founder and CEO, and Garaizar, president, want to round up 100 investors by the end of 2020. And they want these investors to write checks.

"We are not a networking organization. We are an investment organization. We are expecting at some point that you are writing a check to a startup," Maso says. "If we are doing our job properly and we are showing you the right startups, you should be able to make a check at some point." Click here to read more.

Debbie Mercer, a Houston entrepreneur, has designed articles of clothing to empower female athletes. Photo courtesy of Zip Hers

Houston entrepreneur levels the playing field for female runners with new activewear line

running game

It was race day for avid marathon runner, Debbie Mercer. She and her race pack got up early on a brisk winter's day in Chicago, Illinois, piling on warm layers over their compression tights, to run the Chicago Marathon.

Miles into the race, Mercer and her friends made a pit stop at the portable bathrooms. The female runners stood in long lines, awaiting their turns to do their business behind closed doors, while their male friends resorted to quickly and discreetly ducking behind the porta-potties, or finding nearby trees. Precious time ticked by as the women watched their male counterparts continue the race.

"I remember thinking 'I wish there was some way that we could do that too,'" Mercer recalls.

The Houstonian created Zip Hers, an activewear brand that has a full-length zipper lining the bikini area of each pant, to accommodate on-the-go women. The Zip Hers concept and design was intended to level the playing field for women and men when it comes to competitive sports.

"If we're wasting time on a bathroom break and they're not, that holds us back…Maybe it's our little tiny contribution to women's equality. We just really want to help women be the best that they can be," Mercer says.

From full-length pants and tights, to 3-inch compression or loose shorts, Zip Hers has established an array of products suitable active women. However, it was a long and winding road to producing such innovative, high-quality products that could be competitive in such a vast industry of activewear, according to Mercer.

Zip Hers in the making

Photo courtesy of Zip Hers

Mercer kicked off prototype production in 2016. She jumped around to various designers and manufacturers, turning away samples that didn't quite fit her vision for the product. Part of the challenge, Mercer describes, was finding a manufacturer who could manipulate stretch and non-stretch fabric in high-quality ways. Maintaining maximum comfort and a sleek design were challenges when the new variable of a zipper was thrown into the mix.

"It took us a while to get the zipper design perfect so that it would fit well and have a design that was comfortable," Mercer says. "We had to find the right manufacturer to find the skill to make these. We found one in Dallas and one in Houston."

Through trial and error, the Zip Hers design team produced a smooth design that coexists seamlessly with the delicate areas that sit around the zipper. They created a custom-made zipper pull, an invisible, thin disk embossed with the Zip Hers logo.

"Women can easily grab it when they're squatting, and don't have to struggle to find it… you can't even tell that a zipper is there. It's very sleek," Mercer says. "They're all handmade. We have to have special fabric for the panels and…have to have special machines to get the seams just right."

By September 2019, the Zip Hers prototype was finalized and officially launched via the company's online retail site.

Game changers

Photo courtesy of Zip Hers

Zip Hers products, the first of their kind, are sure to change the game for female marathon runners, hikers and any other outdoor activity fanatics, Mercer says. With so many athletic brands available on the internet, Mercer hopes that Zip Hers' innovative approach to active wear, and the unique opportunity they offer to women, will help set the brand apart.

"We really don't see any other products out there like ours…As far as apparel goes, we're the only one," Mercer says.

Since launching last year, Zip Hers has watched their clientele expand with predominantly long distance runners and adventure goers. With the 'athleisure' trend on the rise, they're also seeing more women buying leisurewear for yoga classes, or indoor casual use. Mercer says that she hopes Zip Hers will continue to expand to reach female fishers, hunters, climbers, and even first responders, so that women never have to take off their duty belts.

From various race-day experiences of waiting in long bathroom lines as precious time ticks by, to when nature calls during outdoor activities involving co-ed company, Mercer confronted women's realities by proposing an empowering solution for women.

"Ultimately, it gives women a choice. What's more empowering for women than the power to choose what's best for them?" Mercer says.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”