Now is Houston's chance to create a modern economic cluster around health information and knowledge exchange. Photo by Dwight C. Andrews/Greater Houston Convention and Visitors Bureau

For the most part, Houstonians were either born here or came here in pursuit of economic opportunity — a job of some sort that brought us to Houston, either directly or indirectly. Economic opportunity is part of the DNA of this city. The breadth of opportunities our city affords people from all over our country and all over our world are seemingly endless.

Houston's growth in the 20th century was fueled by large, strategic, capital investments in our region's infrastructure. Railroads, Hobby and Bush airports, the Port of Houston, the Texas Medical Center, NASA's Johnson Space Center, the Astrodome, and our surrounding petrochemical facilities have all been enormous economic drivers of investment, jobs, and prosperity for our region.

We are all familiar with the names of our early city visionaries and leaders. Were it not for their vision and leadership, Houston would still be a backwater town on the bayou, 50 miles inland from the closest seaport. Many of these leaders of early Houston had both a legitimate self-interest and a sense of civic virtue that inspired them to give back to a community that nurtured their success. They strongly believed in building a better Houston both for themselves and for succeeding generations with a can-do community spirit. Much of their success in developing Houston into the international city of today was a result of employing innovative mechanisms for matching private and public funding.

Today, the Texas Medical Center located in Houston is comprised of over 50 hospitals, medical schools, and other institutions that are all dedicated to public health. The TMC itself has an intertwined and symbiotic relationship with Houston and is a case study in how public and private institutions can work together to create such a unique medical complex that has benefited so many — and will benefit so many more in the future.

The good news is that today most institutions and physicians have electronic medical records. The bad news is that there is still a problem sending a patient's data across the street to a different health care provider electronically. This problem is called a lack of "interoperability" of health records, and this remains an unsolved problem nationally.

Making the data available to enable access to the right information at the right time to deliver the right care, is a challenge for every health care community in the country. That unresolved national problem can be Houston's opportunity to offer solutions and to leverage one of its largest industries.

We can transform health care delivery by enabling access to comprehensive electronic patient information when and where needed. There is now a strong consensus that new health information and communication technologies have a critical role to play in building a twenty-first century health care system that is safe, effective, patient-centric and equitable.

Most consumers today carry a powerful computer in their pocket called a smartphone. These consumers, also known as patients, are the most underutilized member of the health care delivery team and the only constant factor in the delivery of care. Moreover, the patient should care most about effective delivery of care and outcome. Notably, the added cost to have the patient involved is essentially zero in relation to the cost of delivery so patients would get better care at less cost.

We grew up thinking that doctor knows best, but that was until Dr. Google showed up able to make virtual house calls, whenever, and on demand. How many industries have we witnessed that were disrupted by the Internet? All indications are that this transformation will increase is size, scope and speed and is set to disrupt the largest industry in the largest economy in the world. We are at the dawn of the consumerization of health care.

Because of the enormous social challenges, there is currently no community in the United States that is an economic cluster for health information technology and health information exchange. Houston has the resources to become that community and create a health care hi-tech economic cluster. This suggestion is no more bold than a proposal to dig the Ship Channel 50 miles, or creating the first domed stadium in the world, or landing a man on the surface of the moon and returning him safely to Earth.

Now is Houston's chance to create a modern economic cluster around health information and knowledge exchange. If we are successful, Houston can then not only legitimately claim to be the home of the largest medical center in the world, but also the best.

------

Manfred Sternberg of Manfred Sternberg & Assoc. PC Attorneys at Law has practiced consumer and commercial law for over 30 years.

Rachel Moncton joins the Houston Innovators Podcast to share why ClassPass chose Houston for its fourth domestic hub and what the consumer tech company has on its horizon for 2021. Photo courtesy of ClassPass

Tech exec shares how she's excited to 'make a splash' in Houston with recent expansion

HOUSTON INNOVATORS PODCAST EPISODE 75

When Rachel Moncton decided she wanted to move back to the United States after years of growing consumer tech company ClassPass internationally, she had no clue where she was going to end up.

The current vice president of marketing had served in various leadership roles for the company, and the powers at be at ClassPass, a consumer-facing tech company that brings together fitness classes and wellness experiences onto one app, decided that Moncton's move would be to spearhead the company's fourth office in Houston.

ClassPass, which was founded in New York City in 2011 before quickly opening its second office in San Francisco. Moncton says a few years ago the company conducted a search for a city that would make for a great expansion and, while Houston was definitely a contender, Missoula, Montana, became the next hub for ClassPass, which has raised over $500 million in venture capital. But, Houston was top of mind for the next expansion.

"When we were thinking about our fourth U.S. office, we wanted something bigger — we're growing quickly and knew we would have to tap into a large talent pool," Moncton says on this week's episode of the Houston Innovators Podcast, noting other elements like Houston's parks, sports teams, culture, universities, and more.

"I get a lot of people saying, 'Houston? That's an interesting choice and not what we'd expect,'" Moncton says. "But that's one of the things we like about it. There's a good startup scene here but not a million different consumer tech companies, so it's nice that we are able to make a bit of a splash."

Last fall, Moncton made her move to Houston to stand up the office virtually, at first, and now the local team is 10 people strong. Currently, ClassPass is looking for its physical space somewhere inside the loop and is hoping to have it open by this summer. Likely, Moncton says, the office will start in a coworking or flexible space that will be able to grow alongside the team.

And speaking of growth, Moncton says ClassPass is still hiring in Houston for roles from sales and finance to customer service and more.

"We are hiring across the board. It's fun for the teams to get to meet people you might not be working with day to day, and it fosters a better sense of empathy and understanding of how the company works," Moncton says. "Even though I lead marketing, it's by no means a marketing hub."

As ClassPass expands its presence, Moncton says she's focused on expanding the company's partners on the app. ClassPass has historically connected users to fitness studios but now is featuring more and more health, wellness, and beauty experiences.

"The technology we've built is to help people find things to book in their city," Moncton says. "There's a lot of (fitness studios) and it can be hard to find what you're looking for. Beauty and wellness are no different."

Moncton shares more about what she's excited about for the future of ClassPass, and how she's experienced Houston so far on the episode. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


Wayt is a new app that makes both sides of a shopping transaction smoother and social distancing compliant. Photo courtesy of Wayt

Houston-area student creates new app to help businesses operate safely during COVID-19

there's an app for that

A 17-year-old high school student from the Houston area stepped up to help his local community, as the coronavirus continues to keep many customers from shopping the way they used to.

The Wayt app, created during the stay-at-home order in March, presents itself as an efficient and easy-to-use platform to streamline shopping during the times of the coronavirus. The app provides businesses and their customers with a platform to communicate making curbside pickup, booking appointments, and joining a virtual line a breeze.

"The platform provides a new set of tools for both the customers and the employees of businesses," says Ethan Saadia, app developer and Wayt creator. "With the use of this app, businesses can streamline the process and remove the hassle of shopping for customers."

The app offers a new way to open businesses by using technology that can manage capacity and keep them connected as many businesses move to curbside pickup. The platform allows customers to receive notifications about their order and tap a button to tell the business they're here, removing the hassle of calling customers to tell them their order is ready.

Wayt provides businesses with the customer name and car information, it even lets them know if the customer wants the order delivered directly to their trunk or other areas of their vehicle. This instant notification system keeps businesses and clients safe allowing them to practice strict social distancing to prevent the spread of COVID-19.

"The use of this app will be able to remove a lot of the anxiousness that we have currently," says Saadia. "It will allow for a more convenient shopping experience as we continue to deal with the effects of the coronavirus pandemic in all of our lives."

The platform also allows businesses to offer shopping appointments to abide with reduced capacity mandates, letting customers pick when they can come in within the constraints customized by the business. The app also makes standing in line while keeping social distancing recommendations easy by having customers tap a button on the app to get in line.

According to Saadia, a lot of these changes — like curbside pickup and virtual lines — are here to stay.

"From my perspective and experiences from my friends and family," says Saadia. "Curbside pickup and virtual lines are definitely here to stay because even before the pandemic, popular places used to have long lines and that presented many new challenges. The pandemic is just accelerating technological change that will make our lives easier."

Saadia, a serial innovator and app developer, started his first company in 2013 called PCs for Me where he sells DIY computer kits that help kids learn computer science. While he expects to continue that venture and Wayt, Saadia says he's conscious that things can change unexpectedly as he enters his senior year.

"I know we live under a very uncertain time and I don't really know what's going to happen with school a month from now or a year from now," says Saadia. "My plan is to keep taking it day by day working on Wayt to improve the user experience and work on other apps that I have on the pipeline."

Ethan Saadia, a 17-year-old high school student, created an app to improve the user experience of shopping during a pandemic.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”