Investors name most promising energy tech startups at annual Houston event

ones to watch

The Rice Alliance for Technology and Entrepreneurship handed out awards to the founders of the most promising companies that pitched. Photo courtesy of Slyworks Photography/Rice Alliance

Nearly 100 energy tech startups pitched at the 19th annual Rice Alliance Energy Tech Venture Forum this week — and over a third of those companies are based in the Houston area.

At the conclusion of the event — which took place on Thursday, September 15, at Rice University, and included a day full of company pitches, panels, and thought leadership — 10 startups were deemed the most promising among their peers. The group was voted on by investors attending office hours ahead of the event.

The Rice Alliance for Technology and Entrepreneurship facilitated nearly 700 meetings between 70 investor groups and 90 ventures, according to the organization. The group of presenting companies included participants from Rice's Clean Energy Accelerator's first two cohorts.

Here are 10 of the energy tech industry's most promising companies — and the technology they are working on that's set to disrupt the status quo.

Arolytics

Based in Calgary and founded in 2018, Arolytics is a software company that specializes in emissions management, ESG performance, and regulatory compliance. The company's platform is able to save its users up to 40 percent of their associated measurement costs and emissions management.

Atargis Energy

Atargis Energy is based in Pueblo, Colorado, and is a a member of Rice's second cohort of its Clean Energy Accelerator. The company has developed a twin hydrofoil-based wave energy converter that creates electric power from ocean waves. The technology is paired with real-time sensors and machine learning to optimize power conversion.

Compact Membrane Systems

Based in Delaware, Compact Membrane Systems, is pioneering membrane systems for decarbonizing hard-to-abate chemical manufacturing and industrial carbon capturing. The technology has the potential to revolutionize the chemicals industry.

Dimensional Energy

Dimensional Energy, based in Ithaca, New York, is transforming carbon dioxide into sustainable aviation fuels and products at market competitive prices. The technology integrates carbon capture, electrolysis, and Fischer Tropsch synthesis.

Kanin Energy

Headquartered in Houston, Kanin Energy works with heavy Industry to turn their waste heat into a clean baseload power source. The platform also provides tools such as project development, financing, and operations.

Orbital Sidekick

Orbital Sidekick, based in San Francisco, is an intelligence and analytics company that specializes in remote detection of environmental hazards by way of hyperspectral satellites. The technology provides actionable insights for its customers.

Power to Hydrogen

Based in Columbus, Ohio, Power to Hydrogen has developed an AEM-based electrolysis technology that produces high pressure, high efficiency hydrogen at low cost via water and renewable energy.

Quino Energy

Another Clean Energy Accelerator Class 2 member, Quino Energy produces flow battery systems with over eight hours of energy storage. The batteries are cheaper than lithium-ion alternatives, as well as being safer and easier to scale.

STARS Technology

Based in Richland, Washington, STARS Technology Corp. is commercializing advanced micro-channel chemical process technology that originally was designed for NASA and the Department of Energy. The company's reactors and heat exchangers are compact, energy-efficient, and more.

Syzygy Plasmonics

Houston-based Syzygy Plasmonics is commercializing its light-reacting energy, which would greatly reduce carbon emissions in the chemical industry. The technology originated out of Rice University.

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Houston energy trailblazer Fervo closes $462 million Series E

Fresh Funds

Houston-based geothermal energy company Fervo Energy has closed an oversubscribed $462 million series E funding round, led by new investor B Capital.

“Fervo is setting the pace for the next era of clean, affordable, and reliable power in the U.S.,” Jeff Johnson, general partner at B Capital, said in a news release.

“With surging demand from AI and electrification, the grid urgently needs scalable, always-on solutions, and we believe enhanced geothermal energy is uniquely positioned to deliver. We’re proud to support a team with the technical leadership, commercial traction, and leading execution capabilities to bring the world’s largest next-generation geothermal project online and make 24/7 carbon-free power a reality.”

The financing reflects “strong market confidence in Fervo’s opportunity to make geothermal energy a cornerstone of the 24/7 carbon-free power future,” according to the company. The round also included participation from Google, a longtime Fervo Partner, and other new and returning investors like Devon Energy, Mitsui & Co., Ltd., Mitsubishi Heavy Industries and Centaurus Capital. Centaurus Capital also recently committed $75 million in preferred equity to support the construction of Cape Station Phase I, Fervo noted in the release.

The latest funding will support the continued buildout of Fervo’s Utah-based Cape Station development, which is slated to start delivering 100 MW of clean power to the grid beginning in 2026. Cape Station is expected to be the world's largest next-generation geothermal development, according to Fervo. The development of several other projects will also be included in the new round of funding.

“This funding sharpens our path from breakthrough technology to large-scale deployment at Cape Station and beyond,” Tim Latimer, CEO and co-founder of Fervo, added in the news release. “We’re building the clean, firm power fleet the next decade requires, and we’re doing it now.”

Fervo recently won Scaleup of the Year at the 2025 Houston Innovation Awards, and previously raised $205.6 million in capital to help finance the Cape Station earlier this year. The company fully contracted the project's capacity with the addition of a major power purchase agreement from Shell this spring. Fervo’s valuation has been estimated at $1.4 billion and includes investments and support from Bill Gates.

“This new investment makes one thing clear: the time for geothermal is now,” Latimer added in a LinkedIn post. “The world desperately needs new power sources, and with geothermal, that power is clean and reliable. We are ready to meet the moment, and thrilled to have so many great partners on board.”

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This article originally appeared on EnergyCapitalHTX.com.

Baylor center receives $10M NIH grant to continue rare disease research

NIH funding

Baylor College of Medicine’s Center for Precision Medicine Models received a $10 million, five-year grant from the National Institutes of Health last month that will allow it to continue its work studying rare genetic diseases.

The Center for Precision Medicine Models creates customized cell, fly and mouse models that mimic specific genetic variations found in patients, helping scientists to better understand how genetic changes cause disease and explore potential treatments.

The center was originally funded by an NIH grant, and its models have contributed to the discovery of several new rare disease genes and new symptoms caused by known disease genes. It hosts an online portal that allows physicians, families and advocacy groups to nominate genetic variants or rare diseases that need further investigation or new treatments.

Since its founding in 2020, it has received 156 disease/variant nominations, accepted 63 for modeling and produced more than 200 precision models, according to Baylor.

The center plans to use the latest round of funding to bring together more experts in rare disease research, animal modeling and bioinformatics, and to expand its focus and model more complex diseases.

Dr. Jason Heaney, associate professor in the Department of Molecular and Human Genetics at BCM, serves as the lead principal investigator of the center.

“The Department of Molecular and Human Genetics is uniquely equipped to bring together the diverse expertise needed to connect clinical human genetics, animal research and advanced bioinformatics tools,” Heaney added in the release. “This integration allows us to drive personalized medicine forward using precision animal models and to turn those discoveries into better care for patients.”

Houston institutions launch Project Metis to position region as global leader in brain health

brain trust

Leaders in Houston's health care and innovation sectors have joined the Center for Houston’s Future to launch an initiative that aims to make the Greater Houston Area "the global leader of brain health."

The multi-year Project Metis, named after the Greek goddess of wisdom and deep thought, will be led by the newly formed Rice Brain Institute, The University of Texas Medical Branch's Moody Brain Health Institute and Memorial Hermann’s comprehensive neurology care department. The initiative comes on the heels of Texas voters overwhelmingly approving a ballot measure to launch the $3 billion, state-funded Dementia Prevention and Research Institute of Texas (DPRIT).

According to organizers, initial plans for Project Metis include:

  • Creating working teams focused on brain health across all life stages, science and medical advances, and innovation and commercialization
  • Developing a regional Brain Health Index to track progress and equity
  • Implanting pilot projects in areas such as clinical care, education and workplace wellness
  • Sharing Houston’s progress and learnings at major international forums, including Davos and the UN General Assembly

The initiative will be chaired by:

  • Founding Chair: Dr. Jochen Reiser, President of UTMB and CEO of the UTMB Health System
  • Project Chair: Amy Dittmar, Howard R. Hughes Provost and Executive Vice President of Rice University
  • Project Chair: Dr. David L. Callender, President and CEO of Memorial Hermann Health System

The leaders will work with David Gow, Center for Houston’s Future president and CEO. Gow is the founder and chairman of Gow Media, InnovationMap's parent company.

“Now is exactly the right time for Project Metis and the Houston-Galveston Region is exactly the right place,” Gow said in a news release. “Texas voters, by approving the state-funded Dementia Prevention Institute, have shown a strong commitment to brain health, as scientific advances continue daily. The initiative aims to harness the Houston’s regions unique strengths: its concentration of leading medical and academic institutions, a vibrant innovation ecosystem, and a history of entrepreneurial leadership in health and life sciences.”

Lime Rock Resources, BP and The University of Texas MD Anderson Cancer Center served as early steering members for Project Metis. HKS, Houston Methodist and the American Psychiatric Association Foundation have also supported the project.

An estimated 460,000 Texans are living with dementia, according to the Alzheimer’s Association, and more than one million caregivers support them.

“Through our work, we see both the immense human toll of brain-related illness and the tremendous potential of early intervention, coordinated care and long-term prevention," Callender added in the release. "That’s why this bold new initiative matters so much."

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