The new $1 million gift will target top recruits. Photo courtesy of University of Houston

One of the most prestigious foundations in Texas has made a generous gift to a local university's fledgling medical department. The M.D. Anderson Foundation has pledged $1 million to the University of Houston College of Medicine, UH announced.

The sizable gift is meant to establish the M.D. Anderson Foundation Endowed Professorship in Medicine, specifically to recruit a leader in health care to join the College of Medicine faculty, according to a press release.

The gift, matched one-to-one by an anonymous donor to create a $2 million endowment, aims to support the new medical school's mission to improve health and health care in underserved communities in Houston and across Texas.

This isn't the first time the M.D. Anderson Foundation has supported UH. The foundation has gifted more than $6 million to UH Libraries, UH Law Center, Hobby School of Public Affairs, and the College of Medicine.

"Innovation in health care requires a fresh approach and a willingness to break down traditional silos to collaborate with experts in other health disciplines such as pharmacy, engineering, law and even data sciences, said Dr. Stephen Spann, founding dean of the UH College of Medicine," in a statement.

"By harnessing the power of data analytics, we can fundamentally change the way we deliver higher quality and cost-effective care to more people. Thanks to the M.D. Anderson Foundation's generosity and vision, we will be able to recruit a new faculty member who can help us greatly to accomplish these goals."

As previously reported, UH received a $50 million gift from an anonymous donor in 2019 to establish the "$100 Million Challenge," meant to recruit top nationally recognized and awarded research faculty for chairs and professorships, designed to inspire another $50 million in investments from additional donors.

Now, the school hopes to utilize these funds to address what the school describes as a "critical primary care physician shortage, especially in low-income and minority communities lacking access to a regular source of care and have gaps in preventative care, which leads to higher rates of sickness, hospitalization, and death."

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This article originally ran on CultureMap.

Lisa and Nicky Holdeman are ensuring a bright future of UH med students. Photo courtesy of University of Houston

University of Houston power couple prescribes major gift for college of medicine

funding future doctors

University of Houston medical students and staff will receive a gift that's just what the doctor ordered.

A prestigious and longtime UH power couple has bequeathed two major gifts a major gift to the school's burgeoning College of Medicine. Dr. Nicky and Lisa Holdeman — who together boast more than 45 years at the university — have established an endowed and chair/professorship and a scholarship for medical students, the school announced.

In their will/trust the Holdemans have established, per UH:

  • The Nicky R. and Lisa K. Holdeman Endowed Professorship/Chair, which will support a clinical teaching faculty member responsible for the oversight and strategic direction of the College of Medicine's clinics, as well as enhancing the student and patient experience.
  • The Nicky R. and Lisa K. Holdeman Endowed Scholarship, which will support students in the College of Medicine, which was founded in 2020 on a social mission to improve health and health care in underserved communities in Houston and across Texas.

The Holdemans say that they were inspired by the UH College of Medicine's mission to address a significant statewide primary care physician shortage and how social determinants of health, such as income, housing, food supply and transportation, contribute to health outcomes.

"I have a true admiration for the comprehensive physician, someone comfortable addressing multiple health issues," Nicky Holdeman relays in a statement. "The physicians being trained at the University of Houston will be well prepared to manage most of the patients, with most conditions, most of the time. That's really what primary care medicine is all about."

As previously reported, UH's medical school will welcome its second class of 30 students this summer and will have 480 students at full enrollment, within the decade.

More on the duo, who have been married for 38 years: A UH biography notes that Nicky, physician and professor emeritus at the UH College of Optometry, served as associate dean for clinical education and executive director of the University Eye Institute during his 30 years at the college. He retired in 2019.

Meanwhile, Lisa joined UH in 2006 and serves as vice chancellor for the UH System and vice president for UH marketing and communications. She works directly with UH System Chancellor and UH President Renu Khator and school leadership.

"This gift is especially gratifying because it comes from two dedicated UH leaders whose professional careers have already contributed so much to our University's success," said Renu Khator. "That kind of enlightened commitment on their part sets an admirable example. I know I speak for many when I express our deep appreciation for their generous support of the College of Medicine and the important work it is undertaking in our community."

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This article originally ran on CultureMap.

The University of Houston broke ground on its new medical school building and named the College of Medicine's inaugural class. Photo via UH.edu

Houston medical school presents inaugural class as construction begins on new building

doctors in training

This month, the University of Houston has taken a couple huge steps toward establishing a prestigious medical school program — the first new medical school to be established in Houston in almost 50 years.

UH has broken ground on its $80 million medical school building that is expected to be completed in 2022, and the program has named its inaugural class.

The new cohort of future doctors is a group diverse in ethnic background and life experience. The school plans to tackle a key issue in public health: the shortage of primary care doctors. These future doctors are charged by the university with eliminating health disparities in underserved urban and rural areas, which often have poorer health outcomes.

The UH College of Medicine received 1,728 applications for its first class of students; 164 applicants were interviewed for the 30 available spots, according to UH. An 18-member admissions committee screened those most likely to pursue primary care.

Here is a breakdown of UH's inaugural medical school class:

  • 30 students
  • 73 percent underrepresented minorities in medicine
  • 63 percent female
  • 57 percent first generation in college
  • 40 percent low socioeconomic status
  • 100 percent Texas resident
  • Five graduates of the University of Texas at Austin; two graduates each from the University of Houston, Baylor, Texas A&M, Houston Baptist, Prairie View A&M, and Rice University

According to the school, the goal is for 50 percent of graduates of the UH College of Medicine to choose primary care specialties including family medicine, general internal medicine, and general pediatrics. For some perspective, nationally, only about 20 percent of medical students choose primary care.

"We were very deliberate in our pursuit of medical students who fit the mission. This is much different than most other medical schools because we need different solutions for the current health care problems facing our city and state," said Dr. Stephen Spann, founding dean of the College of Medicine, in a statement.

Each student will receive a $100,000 four-year scholarship through philanthropy to cover tuition and fees. At full enrollment, the College of Medicine will have 480 students, per the school. The Health 2 Building in the UH Medical District will be the college's temporary home for the first two years until a new $80 million medical school building is completed in 2022. Construction crews broke ground on the new building on June 15, according to the university.

Being part of UH's inaugural medical school is deeply personal for students such as Cenk Cengiz. At 14, Cengiz's family emigrated from Turkey to Houston, but could not afford health insurance. Cengiz attended high school and college without ever seeing a doctor, which attracted him to the field of medicine and peaked his interest in the medical school's unique mission to help underserved communities.

"I came a long way from washing dishes at age 14 at a pizza store," Cengiz said in a statement. "My parents are super proud of me."

Dr. Stephen Spann is the founding dean of the College of Medicine. Photo via uh.edu

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This article originally ran on CultureMap.

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.