Mayor Sylvester Turner, Greentown Labs CEO Emily Reichert, and other guests celebrated the grand opening of Greentown Houston on Earth Day. Photo by Lee Bond/Greentown Labs

On a day that was years in the making, Greentown Labs opened the doors to its new Houston outpost in Midtown yesterday on Earth Day.

The Greentown Houston grand opening event, which was steamed online with limited in-person and outdoor attendance, celebrated the organization's first location outside Somerville, Massachusetts.

"This is a tremendous, tangible milestone not only for Greentown Labs but also for the City of Houston and the energy transition," says Dr. Emily Reichert, CEO of Greentown Labs, in a news release. "Five years ago, climate change wasn't a topic among many conversations in Houston. Things have changed.

"Today, we are so proud to open our second-ever location in the energy capital of the world and we're eager to accelerate the energy transition over the next 10 years," she continues. "Houston is buzzing with incredible climatetech startups, world-leading energy organizations, and a thriving investment community. At Greentown Houston, we aim to bring the ecosystem together and collaborate toward our decarbonized future."

Missed the event? Click here for some significant overheard moments from the Greentown Houston Grand Opening.

The organization also announced new members to its network of partners, including bp, Intel Corporation, Mitsubishi Heavy Industries, White Deer Energy, Ara Partners, Bechtel Corporation, and Mitsubishi Corporation (Americas).

In addition to corporate partners and inaugural startup members, Mayor Sylvester Turner attended the event and welcomed Greentown to Houston.

"There's no better way to celebrate the first anniversary of the Houston Climate Action Plan than to open Greentown Labs Houston," says Mayor Turner. "Attracting and nurturing the next generation of energy companies is a critical piece of our city's ambition to lead the global energy transition. The Climate Action Plan calls for creating 50 Energy 2.0 companies, and thanks to Greentown Labs, we are already halfway there. We are grateful for Greentown Labs and their partners for helping Houston meet our climate goals and become the energy capital of the future."

The 30 inaugural startups will soon move into space in accordance to social distancing. Take a sneak peek at the new facility in the slideshow below.

Celebrating the grand opening

Photo by Natalie Harms/InnovationMap

The grand opening event was streamed online and welcomed select masked guests in-person and outdoors.


Log on to one of these informative online events happening throughout the rest of the month. Getty Images

10+ can't-miss virtual business and innovation events in Houston for November​

Where to be online

November is usually the last busy month for business events before the end of the year and ahead of the holidays, and this year — even though events have pivoted to virtual gatherings — is no different.

From panels and ask-me-anything meetings to summits and startup competitions, here are over 10 Houston innovation events you can attend virtually via online meetings. This month in particular there's the return of The Houston Innovation Summit and the brand new awards program called, The Listies (nominate now for those). Be sure to register in advance, as most will send an access link ahead of the events.

November 5 — Dell Technologies Ask Me Anything

Dell Technologies is hosting an "Ask Me Anything" session for the Ion community. During this time, attendees can ask experts anything in regards to IT pain points during these times. Entrepreneurs may also use this time to brainstorm the back end IT Infrastructure of their business.

The event will take place online on Thursday, November 5, at 10 am. Register here.

November 5-6 — Greentown Labs Climatetech Summit

Join Greentown Labs for its first Climatetech Summit for a deep dive into scaling climate action. Across the two days, attendees will engage with Greentown's pillars of climate action — technology, finance, policy, and justice — discover groundbreaking startups and their climatetech solutions, learn from industry experts, and forge meaningful connections with entrepreneurs, investors, business leaders, policymakers, startup support organizations, and other climate champions.

The event will take place online on Thursday, November 5, and Friday, November 6. Register here.

November 10 — Igniting Leadership: The State of COVID Vaccines

Join Ignite Healthcare Network for a special night of discussion hosted by IGNITE Steering Committee member Susan Feigin Harris about the status of COVID19 vaccine development with Dr. Maria Elena Bottazzi, Co-director of Texas Children's Center for Vaccine Development.

The event will take place online on Tuesday, November 10, at 6 pm. Register here.

November 10-12 — Texas Life Sciences Forum

The Texas Life Science Forum is the premier life science event in Texas that brings together members from industry, emerging life science companies, academic, and investors. The 2020 event will be virtual and will still be the "must attend" event for anyone in the life science industry in Texas or affiliated with innovation at the life science academic institutions. This event represents an opportunity to meet investors, learn about promising life science companies, to learn about opportunities for entrepreneurs, investment professionals, big pharma, academics and business executives serving the life science industry.

The event will take place online on Tuesday, November 10, to Thursday, November 12. Register here.

November 12 — Plaza Tec: Funding Fundamentals

Though Latinx-owned businesses and startups make up at least 38 percent of businesses in the Houston area, there is still a lack of access to capital blocking growth and progress for Latinx founders.

In this discussion presented by The Ion, representatives from baMa and NextSeed will join together to discuss angel investing and crowdfunding options for Latinx founders and what challenges one might face when seeking capital.

The event will take place online on Thursday, November 12, at 5:30 pm. Register here.

November 12 — Women in Tech and Biz

If you're interested in hearing from some badass women in tech and business, come to the virtual Women in Tech + Biz event created by the Liu Idea Lab for Innovation and Entrepreneurship. The event will be split into two sections — one focused on entrepreneurship and the other focusing more on software and engineering — followed by networking.

The event will take place online on Thursday, November 12, at 6 pm. Register here.

November 13 — Climathon 2020: Hacking Solutions to Houston’s Climate Challenges

On Earth Day this year, the City of Houston published its first Climate Action Plan. The plan is the culmination of thousands of volunteer time from industry professionals, policy stakeholders, and community advocates. Together the working groups have laid out a concise plan to address the climate challenges that Houston faces along with maintaining a leadership role in the energy transition. This year's Climathon will look to realize some of the goals of the plan through design sprints led by local subject matter experts in the areas of transportation, energy innovation, building optimization, and materials management.

The event will take place online on Friday, November 13, at 1 pm. Register here.

November 16-20 — The Houston Innovation Summit

The Houston Innovation Summit — THIS — celebrates Houston's innovation ecosystem during Global Entrepreneurship Week (GEW). THIS responds to 2020 with a special focus on the intersection of Impact and Innovation, spotlighting Houstonians at the forefront of education, ecosystems, inclusion, and policy. Join Impact Hub Houston and Houston's startup and small business community for a week of exciting programs and connect with the thinkers, doers, makers and innovators driving Houston forward.

The event will take place online on Monday, November 16, to Friday, November 20. Register here.

November 17 — Struggles and Bubbles: Pivoting during a Pandemic

Join General Assembly Houston to listen to a panel of startup founders who will share their journey and entrepreneurial struggles, and what it really takes to launch a startup during global pandemic, and scale a startup.

The event will take place online on Tuesday, November 17 at 5 pm. Register here.

November 17-19 — Capital Factory's Texas Startup Roadshow

For the first time, Capital Factory is taking its roadshow online. For three days, the organization will be introducing investors to the various innovative cities across the Lone Star State.

Houston will be the city of focus on Wednesday, November 18.

The event will take place online on Tuesday, November 17, to Thursday, November 19. Register here.

November 20 — The Listies

Let's toast to the entrepreneurial spirit of Houston in a time when celebrating victories is more important than ever. Introducing the Listies, brought to you Houston Exponential and InnovationMap, commemorating the launch of HTX TechList, Houston's innovation discovery platform.

The event will take place online on Friday, November 20, at 3 pm. Register here.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”