Rice names inaugural recipients of new grant program that's doling out $360,000

Four Rice University lab-stage innovations are receiving fresh funding to get them closer to commercialization. Photo courtesy of Rice University

Four Houston research projects are splitting hundreds of thousands of dollars in grant funding from Rice University.

After announcing the One Small Step Grant program in September to support Rice-developed, lab-stage innovations, the university has named its inaugural recipients. After receiving nearly 30 applicants, four research projects were selected to share $360,000 in grant funding.

“Being able to fund near-commercial projects represents a leap forward in our mission of supporting the cutting-edge work of our faculty and students and helping bring those to market,” Adrian Trömel, assistant vice president for strategy and investments, says in a news release. “Feedback from industry and investors show that they’re excited on how the One Small Step grants help derisk these technologies, getting them ready to launch. Watch this space for the next generation of leading deeptech companies.”

The selected projects include:

  • PerisBio, developed by Samira Aglhara Fotovat and Samantha Fleury from Rice Professor Omid Veiseh's Lab, focuses on novel, hydrogel-encapsulated engineered "cell factories" for the minimally invasive treatment of endometriosis. The project received a $100,000 award.
  • Solidec, founded by Ryan Duchanois and Yang Xia from Rice Professor Haotian Wang's Lab, is a room temperature, solid-state direct air capture technology. The project received a $100,000 award.
  • HornetX, led by Rice Professor Aditya Mohite's Lab, aims to produce highly stable green hydrogen using a perovskite-based photoelectrochemical cell with leading efficiency. The project received a $80,000 award.
  • Coflux, developed by Jeremy Daum and Alec Ajnsztajn from the labs of Rice Professors Rafael Verduzco and Pulickel Ajayan, focuses on covalent organic framework-based photocatalysts for instream remediation of PFAS (per- and polyfluoroalkyl substances) from water. The project received a $80,000 award.

The Office of Innovation created an investment advisory committee — made up of entrepreneurs, investors and corporate executives across industries — to select these recipients. The grant program was funded by the Office of Innovation, with support from Breakthrough Energy Fellows for climate and energy projects

“The inaugural winners of the One Small Step Grant represent the innovative spirit and dedication to excellence that defines our students and faculty," Rice Chief Innovation Officer Paul Cherukuri says. "We are proud to support these groundbreaking projects on their journey from lab to market."

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Former University of St. Thomas business school dean, Beena George, is taking on a new role at the university: Chief innovation officer. Courtesy of UST

Houston educator plans to lead her university into the future with her new role

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High school graduation numbers are decreasing, and, by 2025, far fewer college freshmen will be starting school. Some project as high as a 15 percent drop, says Beena George, inaugural chief innovation officer of Houston's St. Thomas University.

UST is looking forward to and anticipating changes and challenges within higher education like this, and one of the steps the university has been to create George's position.

"My role is to ferment that culture of innovation," George says. "Not just sit here and think of ideas."

As the school gets ready to welcome students back onto its Montrose campus, the former business dean gets ready to serve in her new role for the first semester. She spoke with InnovationMap about her career, goals, and the role UST plays within the Houston innovation ecosystem.

InnovationMap: What have you learned throughout your career that has prepared you for the role?

Beena George: I've always been interested in solving problems. If I saw something that was an opportunity, and we didn't take advantage of it, I'll keep thinking about it. I've been thinking about what makes me enjoy this role and stage in my career, and I think it's because most roles tend to be mostly operational, but this is thinking of new things and doing things differently and checking your own assumptions. That is what really engages me in my role. My career has given me different opportunities to use this, but not so much as now. When teaching, you have that opportunity every day — engaging students differently. Then as dean, it was about looking at new opportunities and programs for the business school, like our Master of Clinical Translation Management program.

IM: How did this clinical translation program come about?

BG: The idea of clinical translation is essentially to move a discovery from the lab to the patient's bedside — it's the commercialization of life sciences. The program trains students to shepherd a discovery from the lab to the commercial setting so that it's available to patients.It's a combination of business, life sciences, regulatory affairs. It's a one-year online program with some residency periods. It's the only of its kind in Houston and is one of less than 10 in the United States and, to my knowledge, the only of its kind in a business school.

IM: What does innovation mean to the University of St. Thomas and this inaugural position?

BG: I think innovation isn't entirely new on college campuses, but now is a time when higher education is in flux. There has been a lot of changes in the industry and in society in general that's requiring higher education institutions to react in a different way. Some of the things that we've always been doing — creating new programs, moving online, new campuses — now it's even more important to bring that to prominence and figure out how it fits with your university. Things have changed, so the rate at which you're innovating has to increase.

IM: What’s on your to-do list for this first year and within five years?

BG: Since this is a new role, my first goal for the next two to three months is the process of discovery — internally and externally. One of the cool things that's happening in Houston is all these partnerships and collaborations. That's what I'm trying to do — learn about the groups here and outside and make these connections. The other part of it is bringing information in from the outside. There are so many different ways of doing things. For instance, in higher education, it's been historically tied to credit hours. We know now there are many different ways to look at education. That's the kind of conversation I look to get started.

IM: You mention collaboration, and I think that’s key when it comes to higher education institutions within the innovation ecosystem, but how do you see that teamwork affecting the city as a whole?

BG: So I have been so glad to see that, because I've always believed that there has to be some competition — it ensures that everyone performs at their best. But there are some industries where you have to go beyond competition to the next level and manage competition and collaboration at the same time. We have two networks — Texas Medical Center and the academic partnership created by The Ion — and talk about what's happening on your campuses and how we can work together in Houston. There's also the 60x30 Texas, which has different advisory councils that offers that same conversation of collaboration to work together to meet our goals. Those types of conversations are important and having those types of venues to do that can have only a positive effect on Houston.

IM: How is UST finding new ways to prepare its students for the workforce?

BG: One thing that has gained a lot of attention here on campus is providing students with more experiential learning opportunities — more internships and apprenticeships and bringing the industry into the classroom. Carlos Monroy, a professor at UST, and his student worked on a project for the city. This is something that allows us to remain connected to the industry and it gives our faculty the idea of what the Industry needs and they can focus on that in the classroom.

IM: UST recently announced a major “renewal” plan. How is this going to affect innovation efforts on campus?

BG: I think the whole process is about innovation. What we have is an opportunity to recreate ourselves for the next millennium and create a sustainable operating model that will continue to provide for our students. I think it will affect everything.


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Portions of this interview have been edited.

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MD Anderson launches $10M collaboration to advance personalized cancer treatment tech

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The University of Texas MD Anderson Cancer Center and Japan’s TOPPAN Holdings Inc. have announced a strategic collaboration to co-develop TOPPAN Holdings’ 3D cell culture, or organoid, technology known as invivoid.

The technology will be used as a tool for personalized cancer treatments and drug screening efforts, according to a release from MD Anderson. TOPPAN has committed $10 million over five years to advance the joint research activities.

“The strategic alliance with MD Anderson paves a promising path toward personalized cancer medicine," Hiroshi Asada, head of the Business Innovation Center at TOPPAN Holdings, said in a news release.

Invivoid is capable of establishing organoid models directly from patient biopsies or other tissues in a way that is faster and more efficient. Researchers may be able to test a variety of potential treatments in the laboratory to understand which approach may work best for the patient, if validated clinically.

“Organoids allow us to model the three-dimensional complexity of human cancers in the lab, thus allowing us to engineer a powerful translational engine—one that could not only predict how patients will respond to therapy before treatment begins but also could help to reimagine how we discover and validate next-generation therapies," Dr. Donna Hansel, division head of pathology and laboratory medicine at MD Anderson, added in the news release. “Through this collaboration, we hope to make meaningful progress in modeling cancer biology for therapeutic innovation.”

The collaboration will build upon preclinical research previously conducted by MD Anderson and TOPPAN. The organizations will work collaboratively to obtain College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) certifications for the technology, which demonstrate a commitment to high-quality patient care. Once the certifications are obtained, they plan to conduct observational clinical studies and then prospective clinical studies.

“We believe our proprietary invivoid 3D cell culture technology, by enabling the rapid establishment of organoid models directly from patient biopsies, has strong potential to help identify more effective treatment options and reduce the likelihood of unnecessary therapies,” Asada added in the release. “Through collaboration on CAP/CLIA certification and clinical validation, we aim to bring this innovation closer to real-world patient care and contribute meaningfully to the advancement of cancer medicine."

NASA taps Houston-area company to explore low-cost spacecraft delivery

Webster-based Arrow Science and Technology is one of six companies picked by NASA to study low-cost ways to launch and deliver spacecraft for difficult-to-reach orbits.

In all, nine studies will be performed under a roughly $1.4 million award from NASA. Another Texas company, Cedar Park-based Firefly Aerospace, is also among the six companies working on the studies.

“With the increasing maturity of commercial space delivery capabilities, we’re asking companies to demonstrate how they can meet NASA’s need for multispacecraft and multiorbit delivery to difficult-to-reach orbits beyond current launch service offerings,” Joe Dant, a leader of the Launch Services Program at NASA’s Kennedy Space Center in Florida, said in a news release. “This will increase unique science capability and lower the agency’s overall mission costs.”

Arrow is teaming up with Rockville, Maryland-based Quantum Space for its study. Quantum’s Ranger orbital transfer vehicle provides payload delivery services for spacecraft heading to low-Earth and lunar orbits.

Arrow, a Native American-owned small business, offers technical support and hardware manufacturing services for the space and defense industries.

James Baker, founder and president of Arrow, said in a news release that the combination of his company’s deployment systems with Quantum’s Ranger vehicle “allows our customers the ability to focus on the development of their payload[s] while we take care of getting them where they need to be.”

“This is an exciting opportunity to demonstrate the unique capabilities of our highly maneuverable Ranger spacecraft, which will expand NASA’s options for reaching dynamic and challenging … orbits,” Kerry Wisnosky, CEO of Quantum Space, added in the release.

The nine studies are scheduled to be completed by mid-September.

NASA said it will use the studies’ findings “to inform mission design, planning, and commercial launch acquisition strategies for risk-tolerant payloads, with a possibility of expanding delivery services to larger-sized payloads and to less risk-tolerant missions in the future.”

ExxonMobil may pause plans for $7 billion Baytown hydrogen plant

Change of Plans

Spring-based ExxonMobil, the country’s largest oil and gas company, might delay or cancel what would be the world’s largest low-carbon hydrogen plant due to a significant change in federal law. The project carries a $7 billion price tag.

The Biden-era Inflation Reduction Act created a new 10-year incentive, the 45V tax credit, for production of clean hydrogen. But under President Trump’s "One Big Beautiful Bill Act," the window for starting construction of low-carbon hydrogen projects that qualify for the tax credit has narrowed. The Inflation Reduction Act mandated that construction start by 2033. But the Big Beautiful Bill switched the construction start time to early 2028.

“While our project can meet this timeline, we’re concerned about the development of a broader market, which is critical to transition from government incentives,” ExxonMobil Chairman and CEO Darren Woods said during the company’s recent second-quarter earnings call.

Woods said ExxonMobil is working to determine whether a combination of the 45Q tax credit for carbon capture projects and the revised 45V tax credit will help pave the way for a “broader” low-carbon hydrogen market.

“If we can’t see an eventual path to a market-driven business, we won’t move forward with the [Baytown] project,” Woods said.

“We knew that helping to establish a brand-new product and a brand-new market initially driven by government policy would not be easy or advance in a straight line,” he added.

Woods said ExxonMobil is trying to nail down sales contracts connected to the project, including exports of ammonia to Asia and Europe and sales of hydrogen in the U.S.

ExxonMobil announced in 2022 that it would build the low-carbon hydrogen plant at its refining and petrochemical complex in Baytown. The company has said the plant is slated to go online in 2027 and 2028.

As it stands now, ExxonMobil wants the Baytown plant to produce up to 1 billion cubic feet of hydrogen per day made from natural gas, and capture and store more than 98 percent of the associated carbon dioxide. The company has said the project could store as much as 10 million metric tons of CO2 per year.

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This article originally appeared on EnergyCapitalHTX.com.

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