Here's what companies are in the latest cohort for gBETA. Photo courtesy of gBETA

An early-stage accelerator has picked its latest cohort of five Houston companies.

The Fall 2020 cohort of gBETA Houston includes:

  • AllIDoIsCook is founded by Tobi Smith and focused on exposing the world to Africa's cuisine by manufacturing gourmet food products delivered directly to customer doors and available at grocers. Since launching, AllIDoIsCook has built out a manufacturing facility, shipped over 8,000 boxes and generated $1.1 million in revenue all without outside funding.
  • Chasing Watts makes it easy for cyclists to coordinate or find rides with fellow riders in their area with its web-based and native application. The company has over 3,000 users and grew 135 percent from Q2 to Q3 in new ride views.
  • DanceKard, founded by Erica Sinner, is a new dating platform that connects individuals and groups with one another by bringing the date to the forefront of the conversation and making scheduling faster and easier with special promotions featuring local establishments. Since launching in August of 2021, DanceKard has over 170 users on the platform.
  • Dollarito is a digital lending platform that helps the low-income Hispanic population with no credit history or low FICO score access fair credit. Founded by Carmen Roman, Dollarito applies AI into banking, transactional and behavioral data to evaluate the repayment capability more accurately than using FICO scores. The company has1,000 users on their waitlist and plans to beta test with 100 or more customers in early 2022.
  • SeekerPitch, founded by Samantha Hepler, operates with the idea that jobseekers' past job titles and resumes are not always indicative of their true capabilities. Launched last month, SeekerPitch empowers companies to see who jobseekers are as people, and get to know them through comprehensive profiles and virtual speed interviews, and the company already has 215 jobseekers and 20 companies on the platform, with one pilot at University of Houston and three more in the pipeline.

The companies kicked off their cohort in person on October 18, and the program concludes on December 14 with the gBETA Houston Fall 2021 Pitch Night. At this event, each company will present their five-minute pitch to an audience of mentors, investors, and community members.

"The five founding teams selected for our gBETA Houston Fall 2021 cohort are tackling unique problems they have each experienced personally, from finding access to cultural foods, fitness communities and authentic dating experiences to challenges with non-inclusive financing and hiring practices," says Kate Evinger, director of gBETA Houston, in the release. "The grit and passion these individuals bring to their roles as founders will undoubtedly have a tremendous impact in the Houston community and beyond."

The accelerator has supported 15 Houston startups since it launched in Houston in early 2020. The program, which is free and hosted out of the Downtown Launchpad, is under the umbrella of Madison, Wisconsin-based international accelerator, gener8tor.

"Downtown Launchpad is an innovation hub like no other, and I am so proud of what it is already and what it will become," says Robert Pieroni, director of economic development at Central Houston Inc., in the release. "The five startups selected for the gBETA Houston Fall 2021 cohort are exploring new challenges that can become high-impact Houston businesses."

gBETA announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually. The second cohort took place last fall, and the third ran earlier this year.

"These founders are building their companies and benefiting from the resources Downtown Launchpad provides," Pieroni continues, "and the proof is in the data – companies in these programs are creating jobs, growing their revenues and exponentially increasing their funding, which means these small starts up of today, working in Downtown Launchpad, are growing into the successful companies of tomorrow."

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.