Here's what companies are in the latest cohort for gBETA. Photo courtesy of gBETA

An early-stage accelerator has picked its latest cohort of five Houston companies.

The Fall 2020 cohort of gBETA Houston includes:

  • AllIDoIsCook is founded by Tobi Smith and focused on exposing the world to Africa's cuisine by manufacturing gourmet food products delivered directly to customer doors and available at grocers. Since launching, AllIDoIsCook has built out a manufacturing facility, shipped over 8,000 boxes and generated $1.1 million in revenue all without outside funding.
  • Chasing Watts makes it easy for cyclists to coordinate or find rides with fellow riders in their area with its web-based and native application. The company has over 3,000 users and grew 135 percent from Q2 to Q3 in new ride views.
  • DanceKard, founded by Erica Sinner, is a new dating platform that connects individuals and groups with one another by bringing the date to the forefront of the conversation and making scheduling faster and easier with special promotions featuring local establishments. Since launching in August of 2021, DanceKard has over 170 users on the platform.
  • Dollarito is a digital lending platform that helps the low-income Hispanic population with no credit history or low FICO score access fair credit. Founded by Carmen Roman, Dollarito applies AI into banking, transactional and behavioral data to evaluate the repayment capability more accurately than using FICO scores. The company has1,000 users on their waitlist and plans to beta test with 100 or more customers in early 2022.
  • SeekerPitch, founded by Samantha Hepler, operates with the idea that jobseekers' past job titles and resumes are not always indicative of their true capabilities. Launched last month, SeekerPitch empowers companies to see who jobseekers are as people, and get to know them through comprehensive profiles and virtual speed interviews, and the company already has 215 jobseekers and 20 companies on the platform, with one pilot at University of Houston and three more in the pipeline.

The companies kicked off their cohort in person on October 18, and the program concludes on December 14 with the gBETA Houston Fall 2021 Pitch Night. At this event, each company will present their five-minute pitch to an audience of mentors, investors, and community members.

"The five founding teams selected for our gBETA Houston Fall 2021 cohort are tackling unique problems they have each experienced personally, from finding access to cultural foods, fitness communities and authentic dating experiences to challenges with non-inclusive financing and hiring practices," says Kate Evinger, director of gBETA Houston, in the release. "The grit and passion these individuals bring to their roles as founders will undoubtedly have a tremendous impact in the Houston community and beyond."

The accelerator has supported 15 Houston startups since it launched in Houston in early 2020. The program, which is free and hosted out of the Downtown Launchpad, is under the umbrella of Madison, Wisconsin-based international accelerator, gener8tor.

"Downtown Launchpad is an innovation hub like no other, and I am so proud of what it is already and what it will become," says Robert Pieroni, director of economic development at Central Houston Inc., in the release. "The five startups selected for the gBETA Houston Fall 2021 cohort are exploring new challenges that can become high-impact Houston businesses."

gBETA announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually. The second cohort took place last fall, and the third ran earlier this year.

"These founders are building their companies and benefiting from the resources Downtown Launchpad provides," Pieroni continues, "and the proof is in the data – companies in these programs are creating jobs, growing their revenues and exponentially increasing their funding, which means these small starts up of today, working in Downtown Launchpad, are growing into the successful companies of tomorrow."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."