Meet the eighth cohort for gBETA Houston. Photo via gener8tor.com

For the eighth time, a global accelerator and venture group has selected five early-stage Houston tech startups to support and help grow.

In partnership with the Downtown Launchpad, gener8tor began its eighth gBETA cohort in September. The free seven-week, equity-free accelerator provides startups with concierge coaching and access to its national network of mentors, customers, corporate partners, and investors.

“Our partnership with Downtown Launchpad to offer this program to Houston-based companies has been exciting,” Lauren Usher, gener8tor gBETA vice president, says in a news release. “Now in its eighth cohort, gBETA Houston continues to support and bolster the technology industries in Houston.”

Since its launch, gBETA Houston has accelerated 40 companies — the majority led by underrepresented founders — that have gone on to raise more than $8.6 million in funding an created more than 70 jobs.

“We're ecstatic to introduce the gBETA Houston Fall 2023 cohort. Our founders have continued to be in a season of bold ideas, groundbreaking solutions and limitless potential,” Muriel Foster, gBETA Houston director, adds.

The fall 2023 cohort for gBETA includes:

  • KONECTU's AI-powered, user-centric platform transforms the Web3 professional freelance landscape and is currently in beta testing with 30 freelancers. The company was founded by Regina M. Noriega.
  • Founded by Yemi Orogbemi, Nemo processes and analyzes financial data to help business leaders visualize their financial performance to better understand what investors and bankers see when they review the numbers. The company has completed a pilot and a beta with two clients on its waitlist.
  • An all-in-one solution, Loop Health, founded by Shawn Wiggins, is a virtual mental health platform aimed at Black and Latino users. Its holistic monthly subscription service includes two one-on-one therapy sessions and one group session per month, as well as meditation, yoga and fitness content.
  • Founded by Camille Buffalo, Parents Balancing Joys gives a community to parents looking for a support system. The social platform allows parents to find resources that support their needs, like childcare, carpool connections, and friendship. The platform has more than 250 moms in 72 ZIP codes on its waitlist and is currently in its beta-testing phase.
  • Parking Pin, LLC’s parking management software connects people to parking spots with zero hardware.The company, founded by Robert Wilson, has conducted customer discovery calls with 11 universities and is currently beta testing with North Carolina Agricultural and Technical State University.
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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”