This week's Houston innovators come from industries across the spectrum. Courtesy photos

This week in Houston is chock full of events from The Houston Innovation Summit, but before you get too swept away, check out these three innovators to know this week.

We have a life-long innovator whose passion has taken him from industry to industry, a construction specialist joining a growing Houston startup, and a man who let his personal struggles motivate him to find solutions.

Brad Rossacci, creative director at Accenture's Houston innovation hub

Brad Rossacci

Brad Rossacci, creative director for Accenture's Houston innovation hub, talks neuroscience, design, technology, and the upcoming Digital Fight Club on November 20 on this week's episode of the Houston Innovator's Podcast. Photo courtesy of Accenture

The guest on the Houston Innovators Podcast this week is Brad Rossacci, who's passion exudes from him in person — and podcast too. One of his recent passions? The Digital Fight Club, which is coming to Houston on November 20. The event puts two "fighters" on a stage with a referee to discuss various technology topics — cybersecurity, medicine, etc.

"I really fell in love with the approach [the event] takes," Rossacci says. "It takes this format that allows you to share ideas in a very short-form content kind of way." Read (and listen!) more.

Michael Matthews, industry principal at Data Gumbo

Michael Matthews

Data Gumbo has named the newest member of its executive team — and the newest industry it's looking to do business in. Photo courtesy of Data Gumbo

Michael Matthews was tapped to lead a brand new market that Houston blockchain startup, Data Gumbo, has announced an expansion into: Construction. The company uses blockchain to make it easier and faster to process industry contracts, payment, and more.

"The construction industry lags far behind other industries in both productivity improvement and technology adoption, resulting in billions of lost value," Matthews says in a news release. "The way companies come together to execute projects remains essentially the same despite technology's improvement and we have to make fundamental, disruptive changes to deliver more value." Read more.

Brigham Buhler, founder of Ways2Well

brigham buhler

Through his own patient journey, Brigham Buhler saw a need for Ways2Well to exist. Photo via ways2well.com

Sometimes, it's just too hard to find the answers you seek in health care. The waiting rooms, the parking, the forms — it's all a bit much only to leave empty handed. This was Brigham Buhler's experience, and finally, after months, he learned he had a hormone deficiency. Now, Buhler's company, Ways2Well, allows patients to quickly do a blood test at a lab and receive their results digitally.

"While most virtual health care providers focus on sick care — treating patients experiencing symptoms that indicate sickness — Ways2Well is focused on preventative health care," says Buhler. Read more.

Houston-based Ways2Well puts control back into the hands of patients. Photo via ways2well.com

This Houston virtual health care platform makes it easier to get answers

digital check up

As hard as he tried, Brigham Buhler couldn't achieve the weight-loss and fitness goals he'd set in his mid-20s. Plus, he constantly felt tired and stressed out. On top of that, Brigham's entire immediate family has diabetes, and he was exhibiting the warning signs.

Buhler's nutritionist recommended he get his hormones checked. It wound up taking three months to get an initial appointment with a urologist, who then recommended a comprehensive blood test.

The blood work revealed that he did, indeed, have a hormone deficiency. Subsequent hormone treatment, in addition to taking vitamins and supplements to combat various risk factors, got Buhler's endocrine system back on track.

Born out of that frustrating situation and spurred by his more than 15 years in the medical-device industry, Buhler launched Houston-based Ways2Well in 2018. Propelled by a virtual health care platform, the company envisions a better way to treat patients by challenging the traditional health care model.

"While most virtual health care providers focus on sick care — treating patients experiencing symptoms that indicate sickness — Ways2Well is focused on preventative health care," says Buhler, a graduate of the University of Houston.

Through his own patient journey, Brigham Buhler saw a need for Ways2Well to exist. Photo via ways2well.com

Here's how Ways2Well works.

A patient visits the company'swebsite to schedule a blood analysis at a Houston-area location of Quest Diagnostics. (Each year, Quest Diagnostics serves one-third of American adults and half of U.S. physicians and hospitals.)

Before the lab work, the patient discusses health concerns and wellness goals through a virtual appointment with a Ways2Well nurse practitioner.

Once the blood analysis is done, the nurse practitioner reviews the test results during a virtual appointment. The practitioner pinpoints underlying causes of chronic symptoms and potential risks for major conditions like heart disease, cancer, and diabetes. Those three ailments are the main drivers of the $3.5 trillion in annual health care costs racked up in the U.S. Ways2Well strives to reverse the symptoms of these and other chronic illnesses.

Finally, the nurse practitioner shares lifestyle or dietary changes that can reduce the likelihood of developing chronic diseases.

"Our online platform allows you to manage your health care journey from the convenience of your home or office, as long as you have access to a computer or phone and internet," Ways2Well says on its website.

Ways2Well charges nothing for a patient's initial 15-minute consultation. The blood analysis costs $299; Buhler says it goes well beyond what primary care doctors normally offer. The review of the blood analysis costs $120. Follow-up appointments cost $60 each. Neither Ways2Well nor ReviveRx accepts health insurance. However, an insurer might reimburse some out-of-pocket expenses.

The Ways2Well clinical team can prescribe medication, hormone therapy, prescription-grade vitamins and supplements, and other remedies through Ways2Well's partner pharmacy, ReviveRX. Ways2Well and ReviveRx occupy offices in the same building.

Typically, health care providers and pharmacies don't collaborate that closely on patient care. "Ways2Well is bridging that gap to offer better treatment to our patients," Buhler says.

Although ReviveRx is a full-service pharmacy, it doesn't operate like retail pharmacies such as Walgreens and CVS. Rather, patients are referred directly to ReviveRx by Ways2Well or Houston health care providers.

Today, Ways2Well focuses on the Houston market. But Buhler says the 12-employee, self-funded startup aims to expand to other Texas markets, such as Austin, Dallas-Fort Worth, and San Antonio.

"Because Ways2Well is a virtual health care provider that offers appointments via video conferences and leverages the Quest Diagnostics network for blood analysis, Ways2Well can treat patients from anywhere in Texas," he says. "Ultimately, the goal is to make Ways2Well available nationwide, with a team of clinical experts across the U.S."

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Texas nonprofit grants $68.5M to Houston organizations for recruitment, research

Three prominent institutions in Houston will be able to snag a trio of high-profile cancer researchers thanks to $12 million in new funding from the Cancer Prevention and Research Institute of Texas.

The biggest recruitment award — $6 million — went to the University of Texas MD Anderson Center to lure researcher Xiling Shen away from the Terasaki Institute for Biomedical Innovation in Los Angeles.

Shen is chief scientific officer at the nonprofit Terasaki Institute. His lab there studies precision medicine, including treatments for cancer, from a “systems biology perspective.”

He also is co-founder and former CEO of Xilis, a Durham, North Carolina-based oncology therapy startup that raised $70 million in series A funding in 2021. Before joining the institute in 2021, the Stanford University graduate was an associate professor at Duke University in Durham.

Shen and Xilis aren’t strangers to MD Anderson.

In 2023, MD Anderson said it planned to use Xilis’ propriety MicroOrganoSphere (MOS) technology for development of novel cancer therapies.

“Our research suggests the MOS platform has the potential to offer new capabilities and to improve the efficiency of developing innovative drugs and cell therapies over current … models, which we hope will bring medicines to patients more quickly,” Shen said in an MD Anderson news release.

Here are the two other Cancer Prevention and Research Institute of Texas (CPRIT) awards that will bring noted cancer researchers to Houston:

  • $4 million to attract David Sarlah to Rice University from the University of Illinois, where he is an associate professor of chemistry. Sarlah’s work includes applying the principles of chemistry to creation of new cancer therapies.
  • $2 million to lure Vishnu Dileep to the Baylor College of Medicine from the Massachusetts Institute of Technology (MIT), where he is a postdoctoral fellow. His work includes the study of cancer genomes.

CPRIT also handed out more than $56.5 million in grants and awards to seven institutions in the Houston area. Here’s the rundown:

  • MD Anderson Cancer Center — Nearly $25.6 million
  • Baylor College of Medicine — Nearly $11.5 million
  • University of Texas Health Science Center at Houston — More than $6 million
  • Rice University — $4 million
  • University of Texas Medical Branch at Galveston — More than $3.5 million
  • Methodist Hospital Research Institute — More than $3.3 million
  • University of Houston — $1.4 million

Dr. Pavan Reddy, a CPRIT scholar who is a professor at the Baylor College of Medicine and director of its Dan L Duncan Comprehensive Cancer Care Center, says the CPRIT funding “will help our investigators take chances and explore bold ideas to make innovative discoveries.”

The Houston-area funding was part of nearly $99 million in grants and awards that CPRIT recently approved.

Houston space company's lunar lander touches down on the moon in historic mission

touchdown

A private lander on Thursday made the first U.S. touchdown on the moon in more than 50 years, but managed just a weak signal back until flight controllers scrambled to gain better contact.

Despite the spotty communication, Intuitive Machines, the company that built and managed the craft, confirmed that it had landed upright. But it did not provide additional details, including whether the lander had reached its intended destination near the moon’s south pole. The company ended its live webcast soon after identifying a lone, weak signal from the lander.

“What we can confirm, without a doubt, is our equipment is on the surface of the moon,” mission director Tim Crain reported as tension built in the company’s Houston control center.

Added Intuitive Machines CEO Steve Altemus: “I know this was a nail-biter, but we are on the surface and we are transmitting. Welcome to the moon.”

Data was finally starting to stream in, according to a company announcement two hours after touchdown.

The landing put the U.S. back on the surface for the first time since NASA’s famed Apollo moonwalkers.

Intuitive Machines also became the first private business to pull off a lunar landing, a feat achieved by only five countries. Another U.S. company, Astrobotic Technology, gave it a shot last month, but never made it to the moon, and the lander crashed back to Earth. Both companies are part of a NASA-supported program to kick-start the lunar economy.

Astrobotic was among the first to relay congratulations. “An incredible achievement. We can’t wait to join you on the lunar surface in the near future,” the company said via X, formerly Twitter.

Intuitive Machines “aced the landing of a lifetime,” NASA Administrator Bill Nelson tweeted.

The final few hours before touchdown were loaded with extra stress when the lander's laser navigation system failed. The company's flight control team had to press an experimental NASA laser system into action, with the lander taking an extra lap around the moon to allow time for the last-minute switch.

With this change finally in place, Odysseus descended from a moon-skimming orbit and guided itself toward the surface, aiming for a relatively flat spot among all the cliffs and craters near the south pole.

As the designated touchdown time came and went, controllers at the company's command center anxiously awaited a signal from the spacecraft some 250,000 miles (400,000 kilometers) away. After close to 15 minutes, the company announced it had received a weak signal from the lander.

Launched last week, the six-footed carbon fiber and titanium lander — towering 14 feet (4.3 meters) — carried six experiments for NASA. The space agency gave the company $118 million to build and fly the lander, part of its effort to commercialize lunar deliveries ahead of the planned return of astronauts in a few years.

Intuitive Machines' entry is the latest in a series of landing attempts by countries and private outfits looking to explore the moon and, if possible, capitalize on it. Japan scored a lunar landing last month, joining earlier triumphs by Russia, U.S., China and India.

The U.S. bowed out of the lunar landscape in 1972 after NASA's Apollo program put 12 astronauts on the surface. Astrobotic of Pittsburgh gave it a shot last month, but was derailed by a fuel leak that resulted in the lander plunging back through Earth's atmosphere and burning up.

Intuitive Machines’ target was 186 miles (300 kilometers) shy of the south pole, around 80 degrees latitude and closer to the pole than any other spacecraft has come. The site is relatively flat, but surrounded by boulders, hills, cliffs and craters that could hold frozen water, a big part of the allure. The lander was programmed to pick, in real time, the safest spot near the so-called Malapert A crater.

The solar-powered lander was intended to operate for a week, until the long lunar night.

Besides NASA’s tech and navigation experiments, Intuitive Machines sold space on the lander to Columbia Sportswear to fly its newest insulating jacket fabric; sculptor Jeff Koons for 125 mini moon figurines; and Embry-Riddle Aeronautical University for a set of cameras to capture pictures of the descending lander.