How tech boot camps can help solve the Houston innovation equation

Class project

It's been a little over a year since Houston lost out on the Amazon HQ2 bid and left the city pondering its approach to innovation. Houston is known for taking risks and bouncing back from adversity. We're known for growth and entrepreneurship. But are we still known for innovation? Are we positioned for growth as a creative class and digital skills city?

It's my belief that we need to invest in the professional skills of our local workforce and ensure we can attract companies that will help our city and Houstonians thrive. Amazon pointed us in the right direction. It highlighted our need of more professional upskilling programs and increased investment in the city's innovation infrastructure.

At Rice University, we listened, and launched fast-track, intensive tech training programs designed specifically for working adults to help solve these problems. We launched a pilot program in late 2018, a data analytics boot camp in partnership with a national workforce accelerator called Trilogy Education. It was met with such an enthusiastic response from students that we are expanding the initiative by adding programs in cybersecurity and other high demand fields later this year.

These tech boot camps are designed to augment Rice's other efforts to foster innovation in our community like a recent $100 million investment in a new innovation hub for all of Houston and an already ambitious innovation and technology ecosystem, highlighted by the Liu Idea Lab for Innovation and Entrepreneurship, or LILIE, and the Rice Alliance for Technology and Entrepreneurship. Combined, we hope these efforts will help Houston to secure its position as a magnet for technology employers and workers alike.

By many standards, Houston's tech industry is booming. Digital middle-skill jobs — the kinds that provide a stepping stone between lower-paid non-tech roles and high-earning careers in tech — represent 42 percent of overall job postings in Houston. And these jobs are on the rise. Between 2017 and 2018, the number of Houston job postings requiring web development skills rose by 57 percent, earning the city 6th-place ranking among the top 10 U.S. cities for coding job growth.

With numbers like these, it's easy to grow complacent. But Houston is by no means immune to the widening digital skills gap that is holding back business growth nationwide. And unless we create programs to support upskilling and career mobility, even the people currently driving Houston's tech renaissance may struggle to keep their skills sets up to date.

These programs help us address Amazon's core area of critique: innovation. This is something Houston has historically been known for; in 1969 alone, we helped put the first astronaut on the moon and the first artificial heart in a patient. But like all important skills, innovation must be regularly nurtured, enhanced, and relearned.

New, alternative education pathways like technology boot camps bring more diversity to our tech talent pools, a critical component of fostering innovation that is still missing at most technology-focused companies. These employers are starting to look beyond traditional degrees for people who can simply prove they have the skills for the job. The relatively lower barrier to entry for a technology boot camp opens the door for candidates of all races, genders, and walks of life to bring their unique perspectives and insights to an industry sorely in need of more diversity.

As one of the country's most racially diverse metros, Houston reflects the nation's demographic future, and can make a unique contribution to the diversity of our workforce. We already rank among the top five best U.S. cities for women in tech (number four, to be exact). And if the demographics of Rice's earliest boot camp enrollees are any indication, a widespread rollout of these kinds of programs may be a part of Houston's ability to garner the number one spot in coming years. Among our boot camp students to date, 35 percent are white, 20 percent are Hispanic, 17 percent are African American, and 23 percent are Asian. Women made up 25 percent of our first class, a good start that we plan to improve.

Houston has the potential to become a nationwide leader in tech innovation. The problems we face in getting there are complicated, but like all equations, they can be solved with resilience and hard work.

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Robert Bruce is the dean of Rice University's Susanne M. Glasscock School of Continuing Studies.

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Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

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