A panel of Houston innovators explained how impact investment isn't charity. It provides both financial and societal returns. Photo courtesy of SWAN

Houston innovators called for existing and potential investors to focus on impact investing — for the improvement of both society and your bottom line.

SWAN Impact Network, which announced its expansion into Houston earlier last month, is an investment organization that prioritizes funding mission driven startups and educating angels on how to analyze impact investment companies. The organization hosted a launch event and panel at the Ion last week to discuss the process and goals of impact investing and highlighted their own success stories as angel investors. The panelists included Bob Bridge, Kerri Smith, and Emily Reiser, who were moderated by Grace Rodriguez, executive director of Impact Hub Houston.

Emily Reiser, associate director of the Texas Medical Center’s innovation team, said impact investing, though focused on improving people’s lives through innovations, should still rely on typical business models and return profiles.

“It’s not charity investment, it’s investing with an eye towards how that investment is going to also return to the greater society as well as back to your pockets,” Reiser says.

As there was a mix of prospective angel investors and entrepreneurs in attendance at the event, Reiser encouraged the founders to have formal business plans in place before meeting with investors, from setting up customer feedback systems to budgeting estimates.

“In the impact space you’ll get some great enthusiasm from people who want to join your mission to save lives, or change the world, or save the planet but make sure you do all the rest of the work behind that to build out the rest of your business model, figure out how you’re going to sell, get it optioned, and on the market,” Reiser says.

Bob Bridge, the founder and executive director of SWAN, stressed the importance of examining long term consequences of impact-driven startups. Bridge illustrated the importance of doing research into how these startups could unintentionally harm communities before investing in them by discussing the well known shoe manufacturer TOMS, whose business model revolved around matching each pair of purchased shoes by donating a pair to people in developing countries, putting local manufacturers out of business.

“These companies are often just now entering the market place so they can’t measure their actual impact results yet because they’re not delivering services or products yet,” Bridge says. “We look for them to have some sort of data to give us a clue if what they’re doing is going to work … convince us there is efficacy to what you are doing and that your impact solution is competitive.”

Bridge also adds there is no concrete definition of impact investing because every society has different needs to be met through creative solutions, from developing more robust technology to encouraging the hiring of underrepresented minority groups. When making decisions over which companies to invest in, Bridge says he also prioritizes startup teams that are collaborative and transparent.

“We don’t invest in Steve Jobs' kind of personalities … We want people who are always learning from their customers, competitors, and employees,” he explains.

Kerri Smith, executive director of the Rice Alliance Clean Energy Accelerator program, says her team readies their emerging startups to tackle meetings with investors by asking them to quantify the impact of their technology on users.

“We’re seeing a lot of investors as well as boards of directors requiring companies to be more responsive to those kinds of things,” Smith says. “We try to prepare the startups in ways that will make them more ready to answer questions about the impact that they’re having societally as well as financially.”

Austin-founded SWAN Impact Network has entered the Houston innovation ecosystem. Photo via Getty Images

Texas angel investor group expands to make impact in Houston

angels flying in

An angel investment network founded in Austin has announced its entrance into the Houston market.

SWAN Impact Network, which focuses on funding early-stage, impact-driven startups, announced that Houston will be its next market expansion. Founded in 2016, the organization expanded to Dallas two years ago. Now, SWAN is hitting the Bayou City and is actively looking for potential angel investors to join its network.

"Houston is the logical place for us to go because a lot of our deep expertise we developed is grounded around life science, health and wellness, and environmental," Bob Bridge, executive director of SWAN, tells InnovationMap. "There's a lot of people in Houston in the spaces where we've spent most of our time and money."

SWAN, originally founded as the Southwest Angel Network, has grown from several investors to over 80 across Texas. The investors, who meet virtually, range from former entrepreneurs, seasoned investors, and first time angels.

Valerie Tompson, who's serving as the Houston market lead, is an example of someone who was drawn to SWAN's mission, even though she had never invested in startups before.

"I was intrigued by the idea of being able to invest in companies that are making a difference in the world — and it's not a charitable donation," she says, explaining that joining a network allowed for her to learn the ropes and understand the process.

Bridge says they are looking to add 20 Houston investors over the next year. He says they are also interested in adding on volunteer analysts to help in the diligence work of the group. Whether you're a frequent investor or just interested in learning more, SWAN's door is open.

"We encourage new angels not to invest at first — go with us for a ride for six months, learn how we think about companies, see a bunch of companies pitch," Bridge says. "Once they start to get the comfort level up, then they can start making investors. We're very much about helping new angels get comfortable."

Currently, SWAN has two Houston startups — Scriptly Rx and Eisana — in its investment portfolio. In addition to the investor network, SWAN, a nonprofit organization, also has its SWAN Impact Philanthropic Fund that also invests in impact-driven businesses.

SWAN is hosting an event at the Ion on Wednesday, May 31, at 6 pm to celebrate its new Houston expansion, as well as to host a panel discussing impact investing. The event is free to attend, and registration is open.

Valerie Tompson, Houston chapter lead, and Bob Bridge, executive director, will be at the May 31 event. Photos courtesy of SWAN

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CultureMap Emails are Awesome

Nominations are now open for the 2025 Houston Innovation Awards

Calling All Innovators

Calling all Houston innovators: The Houston Innovation Awards return this fall to celebrate the best and brightest in the Houston innovation ecosystem right now.

Presented by InnovationMap, the fifth annual Houston Innovation Awards will take place November 5 at TMC Helix Park.

The awards program will honor the top startups and innovators in Houston across 10 categories, and we're asking you to nominate the most deserving Houston innovators and innovative companies today.

This year's categories are:

  • Minority-founded Business, honoring an innovative startup founded or co-founded by BIPOC or LGBTQ+ representation.
  • Female-founded Business, honoring an innovative startup founded or co-founded by a woman.
  • Energy Transition Business, honoring an innovative startup providing a solution within renewables, climatetech, clean energy, alternative materials, circular economy, and beyond.
  • Health Tech Business, honoring an innovative startup within the health and medical technology sectors.
  • Deep Tech Business, honoring an innovative startup providing technology solutions based on substantial scientific or engineering challenges, including those in the AI, robotics, and space sectors.
  • Startup of the Year (People's Choice), honoring a startup celebrating a recent milestone or success. The winner will be selected by the community via an interactive voting experience.
  • Scaleup of the Year, honoring an innovative later-stage startup that's recently reached a significant milestone in company growth.
  • Incubator/Accelerator of the Year, honoring a local incubator or accelerator that is championing and fueling the growth of Houston startups.
  • Mentor of the Year, honoring an individual who dedicates their time and expertise to guide and support budding entrepreneurs.
  • Trailblazer, honoring an innovator who's made a lasting impact on the Houston innovation community.

Nominations may be made on behalf of yourself, your organization, and other leaders in the local innovation scene. The nomination period closes on August 31, so don't delay — nominate today at this link, or fill out the embedded form below.

Our panel of esteemed judges will review the nominations, and determine the finalists and winners. Finalists will be unveiled on September 30, and the 2025 Houston Innovation Awards winners will be announced live at our event on November 5.

Tickets will go on sale this fall. Stay tuned for that announcement, as well as more fanfare leading up to the 2025 Houston Innovation Awards.

Nominate now:

Interested in Innovation Awards sponsorship opportunities? Please contact sales@innovationmap.com.

MD Anderson launches $10M collaboration to advance personalized cancer treatment tech

fighting cancer

The University of Texas MD Anderson Cancer Center and Japan’s TOPPAN Holdings Inc. have announced a strategic collaboration to co-develop TOPPAN Holdings’ 3D cell culture, or organoid, technology known as invivoid.

The technology will be used as a tool for personalized cancer treatments and drug screening efforts, according to a release from MD Anderson. TOPPAN has committed $10 million over five years to advance the joint research activities.

“The strategic alliance with MD Anderson paves a promising path toward personalized cancer medicine," Hiroshi Asada, head of the Business Innovation Center at TOPPAN Holdings, said in a news release.

Invivoid is capable of establishing organoid models directly from patient biopsies or other tissues in a way that is faster and more efficient. Researchers may be able to test a variety of potential treatments in the laboratory to understand which approach may work best for the patient, if validated clinically.

“Organoids allow us to model the three-dimensional complexity of human cancers in the lab, thus allowing us to engineer a powerful translational engine—one that could not only predict how patients will respond to therapy before treatment begins but also could help to reimagine how we discover and validate next-generation therapies," Dr. Donna Hansel, division head of pathology and laboratory medicine at MD Anderson, added in the news release. “Through this collaboration, we hope to make meaningful progress in modeling cancer biology for therapeutic innovation.”

The collaboration will build upon preclinical research previously conducted by MD Anderson and TOPPAN. The organizations will work collaboratively to obtain College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) certifications for the technology, which demonstrate a commitment to high-quality patient care. Once the certifications are obtained, they plan to conduct observational clinical studies and then prospective clinical studies.

“We believe our proprietary invivoid 3D cell culture technology, by enabling the rapid establishment of organoid models directly from patient biopsies, has strong potential to help identify more effective treatment options and reduce the likelihood of unnecessary therapies,” Asada added in the release. “Through collaboration on CAP/CLIA certification and clinical validation, we aim to bring this innovation closer to real-world patient care and contribute meaningfully to the advancement of cancer medicine."