What started as an idea to get kids to drink more water has turned into a profitable party favor company. Courtesy of My Drink Bomb

What started as a way for Chloé Di Leo to encourage her kids to drink more water is now — just a few months later — a startup making a splash on the wedding industry.

Di Leo, the founder, launched My Drink Bomb LLC in Houston at the beginning of summer 2018. She tells InnovationMap that the product was inspired by bath bombs, fizzing once added to a beverage. She created the company with her husband, William Roberts. Together, they own a few local businesses, and Di Leo also is also a jewelry designer at her own store, Chloé Di Leo & Co.

The first flavor created she created for The Bomb Squad, the line for children, was bubblegum, but now she has seven different flavors online, including Strawberry, Birthday Cake, Watermelon, and more.

"Our kids took some to school and came home with some pocket change," says Di Leo. "They weren't supposed to sell it, but the kids liked it."

One day, her kids came home with $40, and she knew the idea was taking off.

The Bomb Squad line quickly transformed into Mixologi, a version of the product meant to be added to alcohol for cocktails. Di Leo tells InnovationMap that the addition stemmed from dinner parties she was hosting with her husband. She put the five major ingredients of a cocktail into a drink bomb.

"It's basically a mixer you drop in," she says. "We wanted to make it super easy and fun to use."

There are currently 23 Mixologi flavors available online, including Margarita, Moscow Mule, Pina Colada, Cosmo, and more. Custom flavors are available and take six to eight weeks to perfect the flavor and recipe before delivery.

To begin crafting the cocktail flavors, Di Leo says that she traveled to Tulum to spend time with a mixologist in Mexico and came back to the states with recipes for the drink bombs.

"Six months later, here we are," says Di Leo.

The company also offers a hangover bomb, crafted from activated charcoal and zesty tangerine extract to reduce headaches and reduce and release toxins in your body, according to the My Drink Bomb website.

The company gained attention after Sabrina Bryan of The Cheetah Girls reached out to Di Leo after finding the company on Instagram. Bryan wanted Mixologi to supply drink bombs for her wedding in October 2018. Custom flavors are available and take six to eight weeks to perfect the flavor and recipe before delivery.

In Spring 2019, Di Leo shares that My Drink Bomb plans to create and launch a coffee and tea drink bomb. She also hopes to create a drink bombs geared toward detox, anti-aging, health, and fitness, and Di Leo wants to work with a mixologist and a health and fitness expert.

In addition to new flavors, My Drink Bomb is heading to local brick and mortar stores — and she has her eye on a few local boutiques and spas, as well as all 20 flagship Specs store.

"When you have an idea, just keep working hard," Di Leo says. "A simple idea can turn into something beautiful."

Houston-based VineSleuth created a custom algorithm to match you with new wines based on wines you've had in the past. Courtesy of VineSleuth

Houston entrepreneur makes a splash with wine-selecting technology

Sip, sip, hooray

Amy Gross wants to find you the perfect wine. In fact, she wants it so much, she built her company, VineSleuth, around the concept that technology and machine learning could find the best wine to match individual palates.

VineSleuth's custom algorithm is backed by research from sensory scientists at Cornell University, and relies on both data collection and machine learning to determine specific wines that will match an individual customer's tastes. Flavor profiles from thousands of wines are incorporated into her database, and none of those are based on the typical wine scores you'll see in magazines or reviews of wines.

"We have a team that tastes and analyzes wines and inputs their findings. Then, we have a team that codes all of that data," she says.

VineSleuth's technology can be easily overlaid on a restaurant, grocery store, or other vendor's existing web platform or app to provide a tailor-made experience for customers.

"Take a grocery store setting for example," says Gross. "A customer logs into the store using their loyalty card, and their past wine purchases come up. Our technology can analyze those and point to different selections in the store's inventory they'll enjoy."

Think of it as using big data and machine learning to deliver big returns for wine drinkers.

Gross has been deliberate and incremental in how she's grown her company, and she just got a major boost: back in September, she won the 2018 Start Here Now competition, a combination business pitch event and incubator aimed at encouraging women entrepreneurs. She took home the $10,000 Silicon Valley Bank Grand Prize, as well as an app-design concept prize to help her improve the app she created, and a media and PR consultation.

"It was such an affirmation," she says. "To have them validate our work and my future plans."

Planting the seed
It was a slow and steady growth for Gross, who started work on VineSleuth in 2011. But her wine journey started before that.

"My now-husband asked me out on a date, and I'd just graduated college," she says. "I wanted to be sophisticated, so I ordered the house chardonnay. Well, after four or five dates, I started paying attention to what I was drinking, and I developed my palate."

She and her husband and friends of theirs enjoyed exploring wine together, and on a trip to Napa in 2009, Gross noticed something. All six of them were drinking the same wines — mostly Cabernet Sauvignons from Oakville — but they had remarkably different reactions to them.

"I thought, wouldn't it be great if there were an app that told me what I wanted, not what was 'good?'" Gross says.

While she wasn't sure then how to create such an app, she knew she needed to build up her wine knowledge. She started learning about wine in earnest and launched a wine blog. That gave her access to wine vendors and wine makers.

And then, several things happened in steps. Her brother-in-law wrote a basic algorithm that would collect taste profiles and other details from wines, but Gross needed something more. A neighbor who was an applied mathematician took that original algorithm and built on it.

"When I felt brave enough to show it, I shared it with the owners of some wineries I'd developed a business relationship with in the Finger Lakes," says Gross. "They loved the idea, and it turns out one of the winemaker's wife was a sensory scientist at Cornell. At every key place along building this business, it's been about relationships."

Still fermenting
Gross did create an app, but she admits it's not quite where she wants it to be, so she'll likely tweak it over the coming year. In the meantime, she's focused on the B2B future of VineSleuth. While she says the technology her team has created is currently being used for wine, she knows it's possible to take it and expand its capabilities to beer, chocolate, spirits and other consumables.

Building the business has been both an adventure and a learning curve for Gross, whose background is in journalism and PR. But even though she doesn't come from the technology or STEM side, she says her journalism work made her a great researcher – which is exactly what she needed to build VineSleuth. She's also a driven and detail-oriented project manager.

"My team once called me the den mother, keeping everyone on track," she laughed. "And in a way, I am. But I'm also watching the future of AI happening in front me and I really love hanging out with the brilliant people on my team. This is a blast."


Amy Gross is also working on a consumer-facing app, called Wine4Me, that helps users keep track of their favorite wines and gives recommendations for new wines. Courtesy of VineSleuth

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New Houston biotech co. lands $30M for pulmonary fibrosis drug

drug money

Most of us can claim a scar or two on our bodies. But when scarring develops inside the body, it’s known as a fibrotic disorder. A freshly launched Houston company, Oorja Bio Inc., is working on a treatment that can help to repair cells and reduce the damage wrought by the growth of fibrotic tissue in patients.

Late last month, Oorja Bio hit the scene with a pair of big announcements. Not only has the company raised a $30 million Series A thanks to founding investor California-based Westlake BioPartners, but it has also already paved the way for a Phase 2 study to take place this year.

Oorja Bio received Investigational New Drug (IND) clearance from the U.S. Food and Drug Administration (FDA), allowing the company to test its treatment in patients with idiopathic pulmonary fibrosis (IPF), a scarring of the lung tissue. IPF affects more than 150,000 adults in the United States and can result in a range of symptoms from shortness of breath to organ failure and death as it progresses.

Oorja Bio’s lead drug candidate, ORJ-001, was shown in a Phase 1 in-human trial to demonstrate “therapeutically relevant exposure and favorable tolerability” in 64 healthy adult volunteers in whom it was administered daily or weekly, according to a news release. Pre-clinical studies of ORJ-001 showed durable target tissue engagement and biomarker activity in bleomycin-induced lung fibrosis.

Administered subcutaneously, ORJ-001 is intended to improve and even restore function in cells that can reduce the signaling that causes IPF. It stops advancement of IPF and also allows for tissue repair. Currently available treatments for the disease can slow the development of IPF down, but do not address the declining lung function that’s inherent in its progression.

“The clinical and preclinical results from our studies to date give us confidence that ORJ-001 represents a novel treatment approach with the potential to repair and reverse fibrosis and modify disease progression in IPF,” Dr. Janethe Pena, CMO of Oorja Bio, said in the release.

“Our team is energized to deliver on our goal of redefining the future of fibrotic diseases, beginning with ORJ-001,” CEO and founder Sujay Kango added. “As we advance ORJ-001 in the clinic, we are embracing the paradigm shift in our biological understanding of IPF pathology that aligns with the central role of the alveolar epithelium. ORJ-001 was designed with this biology in mind and may provide, for the first time, a therapeutic intervention that repairs and reverses fibrosis and promotes disease modification.”

Most patients live only three to five years following their IPF diagnosis. Soon, ORJ-001 and Oorja Bio could give them a fighting chance.

Axiom Space tops $525M in oversubscribed round, announces Swiss subsidiary

funding boost

Axiom Space tacked on an additional $175 million to a previously announced capital raise, bringing the oversubscribed round to a total of more than $525 million.

Axiom shared in February that it had secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority. In the latest release from the company, Axiom reports that Japan-based MUFG Bank Ltd. joined the round as a new investor, in addition to continued participation from existing backers.

The funding will go toward developing the company's commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

“Investor interest in this round outpaced what we set out to raise, which speaks to the moment we’re in,” Jonathan Cirtain, CEO and president of Axiom Space, said in the news release. “Our partners see what is possible in low-Earth orbit, and they see who is positioned to lead it.”

Axiom announced last month that it planned to open a Japanese subsidiary July 1. Earlier this week, it also shared plans to establish Axiom Space Switzerland, a wholly owned subsidiary based in Lucerne that is also expected to begin operations this summer.

The Switzerland subsidiary aims to establish Axiom's presence in Europe and help it partner with the European Space Agency and other space organizations and companies on the continent.

“Europe is a founding leader in the creation of the commercial space economy, and Switzerland is uniquely positioned to convene the government agencies, research institutions, and industrial entities that will shape its next decade,” Cirtain added in a separate release. “Axiom Space Switzerland facilitates the scaling of development and deployment of the infrastructure that will succeed the International Space Station.”

Texas cashes in among 10 best U.S. state economies in 2026 report

State Economics

A new study gauging the success or decline in economic performance in every state has revealed Texas' economy remains stable in 2026 after it dropped out of the top five to No. 8 last year.

Texas boasts the No. 8 best state economy in the U.S. this year, according to WalletHub's annual "Best & Worst State Economies" report. The personal finance website's analysts ranked all 50 states and the District of Columbia across 28 relevant metrics to measure each state's economic activity and health status, and its "innovation potential."

Notably, Texas leads the nation for the most exports per capita in the U.S. in a five-way tie with Louisiana, Kentucky, North Dakota, and Indiana. Across the study's three main categories, Texas ranked highly for its economic activity (No. 7) and economic health (No. 11), and the state's "innovation potential" rank is the 24th best in the nation.

This is how WalletHub ranked Texas' economic performance, where No. 1 is considered the best and No. 25 is considered average:
  • No. 6 – Change in non-farm payrolls
  • No. 8 – Change in GDP
  • No. 8 – Startup activity
  • No. 11 – Annual median household income
  • No. 18 – Government surplus/deficit per capita
  • No. 21 – Percentage of jobs in high-tech industries
  • No. 30 – Unemployment rate
WalletHub previously ranked Texas one of the top three states to start a business in 2026, with Houston earning its own entrepreneurial acclaim in separate rankings of the best big cities for new businesses and for starting a career.

"U.S. economic growth depends heavily on the performance of individual states, and some contribute more than others," the report's author wrote. "For example, California, Texas, New York and Florida have economies so large that if they were countries, they would rank in the top 20 in the world."

The five states with the worst state economies in 2026 are Rhode Island (No. 47), Maine (No. 48), Louisana (No. 49), Kentucky (No. 50), and West Virginia (No. 51).

The top 10 best state economies for 2026 are:

  • No. 1 – Massachusetts
  • No. 2 – Washington
  • No. 3 – Utah
  • No. 4 – California
  • No. 5 – Delaware
  • No. 6 – North Carolina
  • No. 7 – New York
  • No. 8 – Texas
  • No. 9 – Colorado
  • No. 10 – Florida

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This article originally appeared on CultureMap.com.