In the latest round up of Houston innovation news you may have missed, local venture groups announce new investments, Houston schools launch programs, and more.  Photo via UH.edu

It's been a horrific week for both the city of Houston and the state of Texas. Millions of residents have lost power and/or water due to a winter storm that brought low temps. For this reason, Houston innovation news may have fallen through some of the cracks.

In this roundup of short stories within Houston innovation, the Texas Medical Center's Venture Fund and Chevron Technology Ventures make new investments, University of Houston professors make big moves, both Rice University and UH announce new programs, and more.

TMCx company raises $2 million

The Texas Medical Center Venture Fund announced its latest investment. Noninvasix Inc., a startup working on novel precision oximetry technology announced it has closed an over-subscribed seed round at $2 million led by the TMC Venture Fund with support from Philips and GPG Ventures. The funds will help the company advance product development and attain FDA clearance.

"TMC Venture Fund has been a strong supporter of Noninvasix since our initial investment in the company, and we look forward to our continued partnership with them," says Tom Luby, director of TMC Innovation, in a news release. "The potential of this platform technology to guide better clinical decision-making and improve outcomes has us excited to be part of the effort that brings the optoacoustic technology to the market."

The Noninvasix team has created a solution for the safe, accurate and non-invasive monitoring of infant welfare in the neonatal intensive care unit.

"Brain hypoxia, characterized by restricted blood flow to the brain, accounts for 23 percent of all neonatal deaths worldwide and costs the U.S. healthcare system over $7 billion per year, making the development of an accurate and precise patient monitoring system a top maternal-fetal health priority," says Noninvasix CEO Graham Randall, in the release.

"Noninvasix's novel solution utilizes optoacoustic monitoring of cerebral venous oxygenation to accurately measure the adequacy of the oxygen supply to a baby's brain in real time."

The Cannon and the University of Houston launch new partnership

A UH program has teamed up with a local startup development organization. Photo courtesy of The Cannon

The Cannon has partnered up with the Wolff Center for Entrepreneurship at the University of Houston to launch a semester-long program that will introduce students to the Startup Development Organization Network.Through the new collaboration, students will have access to new opportunities to interact and connect with professionals and advisers.

"We couldn't be prouder to partner with the University of Houston and the Wolff Center for Entrepreneurship to engage with the students that will soon be driving innovation in Houston and beyond," says Jon Lambert, CEO of The Cannon, in a news release. "UH is widely recognized for its excellence in entrepreneurial education and what Dave Cook and his team have built through The Wolff Center is second to none.

"The Cannon is excited for the opportunity to play a role in enhancing the entrepreneurial education journey through helping to provide a bridge between world-class academic programming and the commercial entrepreneurial landscape."

Students at WCE will receive access to The Cannon's online platform, Cannon Connect, as well as access to exclusive events hosted by The Cannon.

Rice University launches new data science program

Rice University is now offering a master's in data science beginning in the fall. Photo courtesy of Rice

Rice University has announced it's creating a Master of Data Science program. The degree is offered through the George R. Brown School of Engineering and managed by the Department of Computer Science. With classes beginning in the fall, applications are now open.

"The field of data science touches almost every industry in our economy," says Scott Rixner, a professor in the Rice's Department of Computer Science, in a press release. "This degree will provide those seeking to find new careers, or to advance in their current careers, the opportunity to acquire an indispensable skill set and to build future-focused critical expertise that will drive future innovation."

The 31-credit program will be offer classes both online and face-to-face, according to the release. The courses will deliver the skills needed to collect, evaluate, interpret and present data for effective decision-making across a variety of industries. The new program joins the online Master of Computer Science degree that was launched in 2019.

"Data science has revolutionized all fields of study and many sectors of the industry where data is central to the scientific or industrial endeavor," says Rice Dean of Engineering Luay Nakhleh, in the release. "Data-driven discovery has complemented hypothesis-driven discovery, and it is here to stay. This degree positions our students for rewarding, life-long careers that provide meaningful impact in design and research in a multitude of industries."

Houston biotech company with COVID-19 treatment enters agreement with UH

A UH-founded biotech company has a new partnership to announce. Image via Getty Images

AuraVax Therapeutics Inc. has entered into an exclusive license agreement with the University of Houston for its intranasal vaccine and therapeutics technology platform. The biotech company is developing novel intranasal vaccines and therapies to help patients defeat debilitating diseases including COVID-19. This new agreement upgrades the optioned intellectual property between UH and AuraVax announced in October.

The vaccine is a nasal inhalant, similar to FluMist, and was developed by Navin Varadarajan, an M.D. Anderson professor of chemical and biomolecular engineering at UH. Varadarajan is a co-founder of AuraVax.

"We are excited to rapidly expand our relationship with the University of Houston to advance the development of this novel intranasal approach to tackle respiratory viruses. We plan to stop COVID-19 at its point of entry — the nasal cavity — and we believe our intranasal platform represents a differentiated solution that will lead to a vaccine to create sustained immunity to COVID-19 and other viruses," says Varadarajan, in the news release.

Chevron Technology Ventures makes latest investment

CTV has recently invested in a geothermal energy company. Photo via eavor.com

Houston-based Chevron Technology Ventures has announced its latest investment in Eavor Technologies Inc., a Canadian company that closed a $40 million funding round. Eavor is working on a scalable geothermal technology and hopes to power the equivalent of 10 million homes by 2030.

Eavor-Loop™, Eavor's technology, uses the natural heat of the earth like a battery and is different from what's on the market because of its scalable and transportatable application — as well as because it produces zero emissions.

Along with CTV, investors included bp Ventures, Temasek, BDC Capital, Eversource1, and Vickers Venture Partners.

"I am delighted that with the funding closed in this round we can look forward to bringing down the cost of clean, dispatchable power to a universally competitive level – an important milestone for renewable energy," says John Redfern, president and CEO of the company, in a news release. "The involvement of companies such as bp and Chevron represents a fantastic endorsement of our technology, the progress we have made to date and the promise for its global scalability."

3 UH engineers named to Academy of Inventors

Three UH engineers have been named senior members of the National Academy of Inventors. Photos via UH.edu

The National Academy of Inventors have named three University of Houston Cullen College of Engineering researchers senior members for 2021.

Hien Nguyen, assistant professor of electrical and computer engineering; Jeffrey Rimer, Abraham E. Dukler Endowed Chair, William A. Brookshire Department of Chemical and Biomolecular Engineering; and Gangbing Song, Moores Professor of Mechanical Engineering, are among the 61 selected for the distinguishment, according to a press release from UH.

"This national distinction honoring the research and scholarship of Drs. Nguyen, Rimer and Song is emblematic of the reputation for innovation fostered at the Cullen College of Engineering," says Paula Myrick Short, senior vice president for academic affairs and provost at UH, in the release. "I congratulate these three outstanding faculty members for this well-deserved recognition."

Nguyen works with biomedical data analysis and artificial intelligence, Rimer's expertise in the processes behind crystal growth and formation, and Song researches the development of actuator systems for aerospace, biomedical and oil exploration applications.

A full list of NAI Senior Members is available on the NAI website.

Aziz Gilani to be recognized nationally

A Houston investor is being recognized nationally. Photo va mercuryfund.com

Aziz Gilani, managing director at Houston-based Mercury Fund, was just selected for an award from the National Venture Capital Association. Gilani is being recognized with the Outstanding Service Award for his work last year outlining and explaining the Paycheck Protection Program from the Small Business Administration to entrepreneurs.

The award will be presented at NVCA's virtual ceremony on March 9. More info on the award ceremony here.

UH and a local company are developing a new COVID-19 vaccine. Photo by Getty Images

University of Houston partners with local company to develop cutting-edge COVID vaccine

COOGS TACKLE COVID

A major Houston university has taken a big leap in the race to battle debilitating diseases such as COVID-19. The University of Houston has entered into an exclusive license option agreement with AuraVax Therapeutics Inc., a Houston-based biotech company developing novel vaccines against aggressive respiratory diseases such as coronavirus, according to a press release.

This means AuraVax has the option to exclusively license a new intranasal COVID-19 vaccine technology developed by Navin Varadarajan, an M.D. Anderson professor of chemical and biomolecular engineering. Varadarajan is a co-founder of AuraVax.

The vaccine is a nasal inhalant, much like FluMist. Based on pre-clinical experimentation, Varadarajan reports his technology not only elicits a mucosal immune response, but also systemic immunity, according to UH.

"We plan to stop COVID-19, a respiratory virus, at its point of entry — the nasal cavity — and we believe our intranasal platform is a differentiated approach that will lead to a vaccine with increased efficacy to create sustained immunity to COVID-19," said Varadarajan in a statement.

So how does it work? Varadarajan is utilizing the spike protein, which helps the virus enter the target cell, and is the major target for neutralizing antibodies as it binds to the ACE 2 cellular receptor, for virus entry. The professor prefers using proteins because of their ability to induce strong immune responses, flexibility and scalability, and the absence of infectious particles, per UH.

Varadarajan's company, AuraVax, has created a next-generation vaccine platform that combines the potential of in-home administration with the ability to deliver complete immunity. The technology has been validated for COVID-19 in initial animal studies and results in immunity measured by both B-cell and T-cell responses.

"We believe AuraVax has a competitive advantage given the immune responses and a supply chain that is well-suited for widespread distribution and self-administration distribution," said Varadarajan. "We are excited to be collaborating with the University of Houston and look forward to future success by advancing the development of this novel intranasal vaccine technology to address a multitude of respiratory viruses, starting with COVID-19."

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This article originally ran on CultureMap.

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Houston climatetech company plans groundbreaking sustainable aviation fuel facility

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Houston-based Syzygy Plasmonics announced plans to develop what it calls the world's first electrified facility to convert biogas into sustainable aviation fuel (SAF).

The facility, known as NovaSAF 1, will be located in Durazno, Uruguay. It is expected to produce over 350,000 gallons of SAF annually, which would be considered “a breakthrough in cost-effective, scalable clean fuel,” according to the company.

"This is more than just a SAF plant; it's a new model for biogas economics," Trevor Best, CEO of Syzygy Plasmonics, said in a news release. "We're unlocking a global asset class of underutilized biogas sites and turning them into high-value clean fuel hubs without pipelines, costly gas separation, or subsidy dependence.”

The project is backed by long-term feedstock and site agreements with one of Uruguay's largest dairy and agri-energy operations, Estancias del Lago, while the permitting and equipment sourcing are ongoing alongside front-end engineering work led by Kent.

Syzygy says the project will result in a 50 percent higher SAF yield than conventional thermal biogas reforming pathways and will utilize both methane and CO2 naturally found in biogas as feedstocks, eliminating the need for expensive CO2 separation technologies and infrastructure. Additionally, the modular facility will be designed for easy replication in biogas-rich regions.

The new facility is expected to begin commercial operations in Q1 2027 and produce SAF with at least an 80 percent reduction in carbon intensity compared to Jet A fuel. The company says that once fully commercialized the facility will produce SAF at Jet-A fuel cost parity.

“We believe NovaSAF represents one of the few viable pathways to producing SAF at jet parity and successfully decarbonizing air travel,” Best added in the release.

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This article originally ran on EnergyCapital.

Houston company ranks No. 13 worldwide on Forbes Global 2000 list

World's Biggest Companies

More than 60 Texas-based companies appear on Forbes’ 2025 list of the world’s 2,000 biggest publicly traded companies, and nearly half come from Houston.

Among Texas companies whose stock is publicly traded, Spring-based ExxonMobil is the highest ranked at No. 13 globally.

Rounding out Texas’ top five are Houston-based Chevron (No. 30), Dallas-based AT&T (No. 35), Austin-based Oracle (No. 66), and Austin-based Tesla (No. 69).

Ranking first in the world is New York City-based J.P. Morgan Chase.

Forbes compiled this year’s Global 2000 list using data from FactSet Research to analyze the biggest public companies based on four metrics: sales, profit, assets, and market value.

“The annual Forbes Global 2000 list features the companies shaping today’s global markets and moving them worldwide,” said Hank Tucker, a staff writer at Forbes. “This year’s list showcases how despite a complex geopolitical landscape, globalization has continued to fuel decades of economic growth, with the world’s largest companies more than tripling in size across multiple measures in the past 20 years.”

The U.S. topped the list with 612 companies, followed by China with 317 and Japan with 180.

Here are the rest of the Texas-based companies in the Forbes 2000, grouped by the location of their headquarters and followed by their global ranking.

Houston area

  • ConocoPhillips (No. 105)
  • Phillips 66 (No. 276)
  • SLB (No. 296)
  • EOG Resources (No. 297)
  • Occidental Petroleum (No. 302)
  • Waste Management (No. 351)
  • Kinder Morgan (No. 370)
  • Hewlett Packard Enterprise (No. 379)
  • Baker Hughes (No. 403)
  • Cheniere Energy (No. 415)
  • Corebridge Financial (No. 424)
  • Sysco (No. 448)
  • Halliburton (No. 641)
  • Targa Resources (No. 651)
  • NRG Energy (No. 667)
  • Quanta Services (No. 722)
  • CenterPoint Energy (No. 783)
  • Coterra Energy (No. 1,138)
  • Crown Castle International (No. 1,146)
  • Westlake Corp. (No. 1,199)
  • APA Corp. (No. 1,467)
  • Comfort Systems USA (No. 1,629)
  • Group 1 Automotive (No. 1,653)
  • Talen Energy (No. 1,854)
  • Prosperity Bancshares (No. 1,855)
  • NOV (No. 1,980)

Austin area

  • Dell Technologies (No. 183)
  • Flex (No. 887)
  • Digital Realty Trust (No. 1,063)
  • CrowdStrike (No. 1,490)

Dallas-Fort Worth

  • Caterpillar (No. 118)
  • Charles Schwab (No. 124)
  • McKesson (No. 195)
  • D.R. Horton (No. 365)
  • Texas Instruments (No. 374)
  • Vistra Energy (No. 437)
  • CBRE (No. 582)
  • Kimberly-Clark (No. 639)
  • Tenet Healthcare (No. 691)
  • American Airlines (No. 834)
  • Southwest Airlines (No. 844)
  • Atmos Energy (No. 1,025)
  • Builders FirstSource (No. 1,039)
  • Copart (No. 1,062)
  • Fluor (No. 1,153)
  • Jacobs Solutions (1,232)
  • Globe Life (1,285)
  • AECOM (No. 1,371)
  • Lennox International (No. 1,486)
  • HF Sinclair (No. 1,532)
  • Invitation Homes (No. 1,603)
  • Celanese (No. 1,845)
  • Tyler Technologies (No. 1,942)

San Antonio

  • Valero Energy (No. 397)
  • Cullen/Frost Bankers (No. 1,560)

Midland

  • Diamondback Energy (No. 471)
  • Permian Resources (No. 1,762)
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A version of this article originally appeared on CultureMap.com.

Texas plugs in among states at highest risk for summer power outages in 2025

hot, hot, hot

Warning: Houston could be in for an especially uncomfortable summer.

A new study from solar energy company Wolf River Electric puts Texas at No. 2 among the states most at risk for power outages this summer. Michigan tops the list.

Wolf River Electric analyzed the number of large-scale outages that left more than 5,000 utility customers, including homes, stores and schools, without summertime electricity from 2019 to 2023. During that period, Texas experienced 7,164 summertime power outages.

Despite Michigan being hit with more summertime outages, Texas led the list of states with the most hours of summertime power outages — an annual average of 35,440. That works out to 1,477 days. “This means power cuts in Texas tend to last longer, making summer especially tough for residents and businesses,” the study says.

The Electric Reliability Council of Texas (ERCOT), which operates the electric grid serving 90 percent of the state, predicts its system will set a monthly record for peak demand this August — 85,759 megawatts. That would exceed the current record of 85,508 megawatts, dating back to August 2023.

In 2025, natural gas will account for 37.7 percent of ERCOT’s summertime power-generating capacity, followed by wind (22.9 percent) and solar (19 percent), according to an ERCOT fact sheet.

This year, ERCOT expects four months to surpass peak demand of 80,000 megawatts:

  • June 2025 — 82,243 megawatts
  • July 2025 — 84,103 megawatts
  • August 2025 — 85,759 megawatts
  • September 2025 — 80,773 megawatts

One megawatt is enough power to serve about 250 residential customers amid peak demand, according to ERCOT. Using that figure, the projected peak of 85,759 megawatts in August would supply enough power to serve more than 21.4 million residential customers in Texas.

Data centers, artificial intelligence and population growth are driving up power demand in Texas, straining the ERCOT grid. In January, ERCOT laid out a nearly $33 billion plan to boost power transmission capabilities in its service area.