Overheard: Innovators sound off on future of work, converging industries at Houston House at SXSW 2024

Eavesdropping in Austin

Houston House at SXSW 2024 featured conversations about startup scaling, tips from CEOs, and more. Photo via Allie Danziger/LinkedIn

Houston innovators talked big topics at SXSW 2024 — from the startup scaling and converging industries to the future of work.

Houston House, which was put on by the Greater Houston Partnership on March 11, hosted four panels full of experts from Houston. If you missed the day-long activation, here are some highlights from the experts who each commented on the future of the Bayou City when it comes to startups, technology, innovation, and the next generation's workforce.

"When we think about Houston, we think about access to at-scale infrastructure, amenities, and workforce and talent pools."

— Remington Tonar, co-founder and chief growth officer at Cart.com, says about why the company chose to return its headquarters back to Houston last year. One of these amenities, Tonar explained, is Houston's global airports.

"If New York and Austin had a baby, it would be Houston, because you have friendly people with a big-city culture."

— Mitra Miller, vice president and board member of Houston Angel Network, says, adding that Houston has a cost efficiency to it, which should be at the forefront of founders' minds when considering where to locate.

"We are not only attracting global talents, we are also attracting global wealth and foreign investments because we are the rising city of the future. We are the global launch pad where you can scale internationally very quickly."

— Sunny Zhang, founder of TrueLeap, says adding how there's a redistribution of global workforce happening when you consider ongoing global affairs.

"We overwhelmingly as a company, and my co-founder would agree, knew we had to go the Houston path. And we started funneling a lot more resources here."

— Carolyn Rodz, co-founder and CEO of Hello Alice, says, explaining that the pandemic helped equalize the talent across the country, and this has been to the benefit of cities like Houston.

"Houston is here with arms open, welcoming people and actively recruiting."

— Sean Kelly, co-founder and CEO of Amperon, says, emphasizing how Texas has made moves to being business friendly. Amperon was founded in New York, before moving to Houston a couple years ago.

"There is a revolution starting to happen in Houston right now."

— Trevor Best, co-founder and CEO of Syzygy Plasmonics, says, first commenting on the momentum from Rice University, where his company's technology originates from. But, as he adds, when you compare the ecosystem when the startup was founded in 2019 to where it's at now, "there is so much more happening."

"Houston has a critical mass in terms of aerospace."

— Stephanie Munez Murphy of Aegus Aerospace says, saying specifically that NASA's Johnson Space Center holds some responsibility for that. "JSC is the home of opening up space commercialization."

"There's diversity in industries people are coming from, but also in terms of experience and expertise that (Houstonians) have."

— Robyn Cardwell of Omniscience says, adding that Houston's diversity goes further than just where people originate from. "Houston has all these pieces put together ... for growing and scaling organizations," she adds.

"I've worked with thousands of students in Houston who are actively looking to better themselves and grow their career post college or post high school and go into the workforce."

— Allie Danziger of Ascent Funding says, adding that Gen Z, which is already entering the workforce, is entrepreneurial and ready to change the world. "Seeing the energy of Houstonians is just thrilling," she adds.

"We're working together in the Houston community. ... There are so many opportunities to collaborate but we need conveners."

— Stacy Putman of INEOS says, adding that within industry there has been a lack of discussion and collaboration because of competition. But, as she's observing, that's changing thanks to conveners at colleges or at the Greater Houston Partnership.

"The opportunity for Houston is that everybody has to step up to be in some way, shape, or form helping us with this."

— Raj Salhotra of Momentum Education says about supporting the future workforce of Houston, including low-income household students.

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This week's roundup of Houston innovators includes Allie Danziger of Ascent Funding, Adrian Trömel of Rice University, and Michael Suffredini of Axiom Space. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from education to space tech — recently making headlines in Houston innovation.

Allie Danziger, senior vice president and general manager of student success at Ascent Funding

Allie Danziger joins the Houston Innovators Podcast to discuss her edtech startup Ampersand's exit. Photo courtesy of Ampersand

For the second time in less than six years, Houston entrepreneur Allie Danziger has navigated a company through an exit. But, with the two exists under her belt, Danziger says the two transactions could not be any more different.

Danziger founded Integrate Agency, a digital-focused public relations firm, in 2009 and sold it to another marketing and PR firm based in Austin in 2018. She founded her next company, Ampersand Professionals, in 2020 to address the challenges for upskilling young professionals to prepare them for success in the workplace — something employers really wanted, but struggled to do consistently.

Last month, Ampersand was acquired by Ascent Funding, a college loan provider that's building out a platform to support its college-aged borrowers. In this week's episode of the Houston Innovators Podcast, Danziger shares how this opportunity came about and looks back on these two pivotal deals. Read more.

Adrian Trömel, assistant vice president for strategy and investments at Rice University's Office of Innovation

In his new role, Adrian Trömel will oversee the creation of the Rice Nexus, an innovation hub within the Ion that aims to bridge the gap between the university and Houston's innovation ecosystem. Photo courtesy of Rice

Rice University’s Office of Innovation has named Houston materials scientist-turned-entrepreneur Adrian Trömel as its new assistant vice president for strategy and investments.

Trömel founded non-invasive neurostimulation medical device company CNX Medical at the Texas Medical Innovation Institute in 2019 and most recently served as chief growth officer for Hamilton Health Box, which brings an on-site care team to company offices.

In his new role, Trömel will oversee the creation of the Rice Nexus, an innovation hub within the Ion that aims to bridge the gap between the university and Houston's innovation ecosystem. He will also lead the creation of a translational research grant fund and a university-affiliated venture fund for Rice-affiliated entrepreneurs. Read more.

Michael Suffredini, CEO and president of Axiom Space

Axiom Space CEO Michael Suffredini has announced the company's series C round with support from Aljazira Capital. Photo courtesy of Axiom Space

Houston has another unicorn — a company valued at $1 billion or more — thanks to a recent round of funding.

Axiom Space released the news this week that it's closed its series C round of funding to the tune of $350 million. While the company didn't release its valuation, it confirmed to Bloomberg that it's over the $1 billion threshold. Axiom reports that, according to available data, it's now raised the second-most funding of any private space company in 2023 behind SpaceX.

Saudi Arabia-based Aljazira Capital and South Korea-based Boryung Co. led the round. To date, Axiom has raised over $505 million with $2.2 billion in customer contracts, according to the company.

“We are honored to team with investors like Aljazira Capital, Boryung and others, who are committed to realizing the Axiom Space vision,” Axiom Space CEO and president Michael Suffredini says in a news release. “Together, we are working to serve innovators in medicine, materials science, and on-orbit infrastructure who represent billions of dollars in demand over the coming decade. Read more.

Allie Danziger joins the Houston Innovators Podcast to discuss her edtech startup Ampersand's exit. Photo courtesy of Ampersand

How this Houston edtech startup's acquisition is primed to further advance platform reach, impact

HOUSTON INNOVATORS PODCAST EPISODE 200

"Integrate definitely was not built to sell — I didn't even know that people sold businesses when I was 24 (and started the agency," Danziger, who worked in PR her entire career at that time, says, adding that she thought she'd work at the company her whole life before passing it down to her children. "It ended up being a life-changing experience and opportunity because it did open my eyes up to other other things that I could do professionally — and also just kind of like the way that businesses are structured and run."

One of those things she considered post acquisition was upskilling entry-level employees. At Integrate, she hired a lot of interns and recent college graduates. She recognized there was a gap in the market. The first problem she identified was the need to match interns to positions at companies in an optimized way. While that's how the company started, it pivoted as Danziger says she saw the bigger need not for finding interns, but for making sure they were ready for their positions from the start.

"Most business leaders need their interns and entry-level employees starting day one with an understanding of how to communicate, and they don't really have the resources to teach them some of these skills," she explains.

Once the Ampersand platform, which has tons of resources and hours of instruction loaded on it, the challenge was finding the stakeholders that wanted the platform to exist — her potential customers. Was it the colleges or the employers? Through this journey, she realized that college loan lenders are part of that equation too.

"The lenders — the ones who are giving the student loans — they're the ones who really need them to be successful in the workplace," Danziger explains, saying the success of their loan recipients ensures a timely payout for the lender. "Their business model is predicated on students being successful, and I'd always known that, but not quite known what to do with that knowledge."

Danziger says the idea for acquisition, while always in the back of her mind, really became a possibility when she went out to raise funding.

"You're always raising money, and you're always for sale," Danziger says of the startup journey.

When a potential investor raised the idea of being a potential acquirer, Danziger says she started doing some soul searching. The right acquisition deal could help her address the milestones she wanted to reach with investment funding — growing her team, expanding her technology, and broadening reach. Through a diligent process, Danziger decided on Ascent from a few other potential acquirers.

"I'm not going anywhere. I want to still keep solving this problem, but with a larger team and larger resources," she says. "Either I could go find that myself, or I could join forces we could join forces with an established organization."

Danziger says her role at Ascent is still being constructed in terms of scope and responsibilities, but her title as of now is senior vice president and general manager of student success. She will lead the company's educational program that focuses on equipping students with skills from education to employment.

She shares more on the acquisition process — including her advice to startups thinking about the M&A path. Listen to the interview here — or wherever you stream your podcasts — and subscribe for weekly episodes.

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Houston brain health co. secures $6.5M for rare disease study

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Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

Elon Musk's SpaceX is about to make its debut on Wall Street

Money Moves

Elon Musk's rocket company SpaceX will make its debut on Wall Street Friday, June 12, and both institutional and retail investors are expected to gobble up the 555.6 million shares going up for sale at $135 apiece. Musk, already the world's richest man, could become its first trillionaire.

SpaceX is likely to become the biggest IPO ever, with proceeds of around $75 billion. SpaceX hopes to become the first company to send people to Mars. In fact, part of Musk’s future compensation depends on SpaceX eventually establishing a colony of at least 1 million people on the red planet.

Why SpaceX is going public now

In a video conference on Musk's social media platform X, he told JPMorgan CEO Jamie Dimon that people have suggested for the last 10 years that he take SpaceX public. He's doing it now because the company plans to put 100,000 next-generation Starlink satellites into orbit. Deploying AI data centers in space is a “massive new growth base and you need capital for that,” he said.

Going public provides access to the capital that SpaceX needs. But it also exposes it to more scrutiny from shareholders and more regulatory oversight. That includes filing quarterly financial reports, which critics say incentivizes short-term thinking over longer-term planning and creates unnecessary costs for a company. Securities regulators are currently soliciting public comment on a proposal to require public companies to file the financial reports only twice every year.

How the IPO impacts the company

Musk will hold the majority of a special class of shares, giving him control over decisions related to company strategy, finances and personnel. On the latter, because of his ownership of most of these Class B shares, the only person who can fire Musk as CEO is Musk.

The company credits Musk with being the “driving force” behind its growth, innovation and success. But what happens if Musk is no longer in the picture? SpaceX warns that the loss of Musk could disrupt its ability to execute its strategy as well as hurt its “reputation and relationships with customers, partners and other stakeholders.”

The company also warns that finding a replacement with the same skills and experience as Musk would be time-consuming, if not nearly impossible. As Wedbush Securities analyst Dan Ives wrote Wednesday, “At the end of the day Musk is SpaceX and SpaceX is Musk.”

What could make or break SpaceX

Currently in the test phase, the gigantic reusable Starship rocket is key to SpaceX realizing Musk's ambitions. Much of the commercial space business hinges on SpaceX developing Starship’s capability to be fully reusable and hearty enough for a quick turnaround between flights. If that doesn't happen, SpaceX warns that putting data centers and satellites in space will take longer and cost more money, meaning it risks customers bailing on the company.

Analysts say that by pioneering reusable rockets, SpaceX has established a clear lead on competitors such as Blue Origin, led by Amazon founder Jeff Bezos. The Starlink satellite business competes with, among others, AST SpaceMobile – which is relying on a SpaceX rocket to send its latest generation of satellites into orbit next week.

The prospectus filed last week says SpaceX’s biggest potential market is the sale of business-oriented artificial intelligence products designed to transform how people get work done. It’s an opportunity SpaceX predicts would be worth $22.7 trillion if it could somehow dominate rivals like Anthropic, OpenAI and Microsoft in a highly competitive industry. But the prospectus shows no clear path to profitability for the xAI business, which merged with SpaceX earlier this year.

Why Wall Street is paying attention

If the SpaceX IPO is as successful, the stock could quickly join the Nasdaq 100, a widely followed index that tracks the 100 largest non-financial companies in the composite. That's important because some popular funds, such as the $460 billion QQQ exchange-traded fund, mimic the index and will automatically buy whatever is listed in the index.

Nasdaq recently changed its rules to allow select companies to enter the Nasdaq 100 after just 15 trading days.

S&P Dow Jones Indices, on the other hand, is sticking to established and more traditional thresholds that will not allow SpaceX or other companies with gargantuan IPOs faster entry into its S&P 500 index. That means even high-profile companies will still need to wait for their stocks to trade a full 12 months before they can enter the index.

Companies want to be in the S&P 500 in particular because it's arguably the most important index on Wall Street, with trillions of dollars either mimicking it exactly or benchmarked against it. Vanguard's VOO fund that tracks the S&P 500 has roughly $950 billion invested in it, for example.

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