3 Houston innovators to know this week

Who's who

This week's innovators to know in Houston includes Tim Neal of GoExpedi, Shay Curran of UH, and Arun Gir of iEducate. Photos courtesy

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three gentlemen representing a diverse set of industries — from nanotech and higher education to industrial e-commerce and education.

Tim Neal, CEO of GoExpedi

Tim Neal, CEO of Houston-based GoExpedi, shares how his company plans to scale following its recent series C closing. Photo by Colt Melrose for GoExpedi

Timing is everything, and Tim Neal says it's been a key factor in his company's success. GoExpedi acts as an Amazon of industrial business, basically. Just as the e-commerce platform has made online ordering easy, trackable, and fast, so has GoExpedi for industrial parts. And, thanks to companies like Amazon and on-demand ordering in general, this type of fast and reliable service is what everyone expects now.

"The labor pool in the oil and gas space in particular — 50 percent of it turn it over. Now you're no longer having these tradesmen who are 60-plus years old and walking encyclopedias. You have a younger workforce that's used to buying on eCommerce and their daily life. So, it's helping them by technical parts in a not technical way," Neal says in a Q&A with InnovationMap. "We just had a pool of clients who were more tech native and who had more familiarity with transacting online." Click here to read more.

Seamus Curran, CEO and founder of Integricote

University of Houston professor and entrepreneur, Seamus Curran, has pivoted amid the pandemic to use his nanotechnology expertise to help reduce the spread of COVID-19. Photo courtesy of Integricote

Seamus Curran's life went from juggling teaching, research, and running his startup from early morning to late at night every day to working and teaching from home when the pandemic hit. He started looking into the virus and realized his nanotechnology actually has a real application in protecting people. First, he started coating masks. Lately he's been working on a new line of protection.

"The big thing for me when we were shut down was that people couldn't go to work or school. The country can't live that way — but you can't send people back to work in a world that's not safe," Curran says in this week's episode of the Houston Innovators Podcast. "How do you create a safer environment? That's the thing that really got me going in the beginning in the summer. We looked at filters." Click here to read more and stream the episode.

Arun Gir, CEO of iEducate

Houston-based iEducate is connecting local tutors and mentors to students. Photo courtesy of iEducate

Now more than ever, young students need hands-on instruction to keep up in their studies, which for so many still are being conducted virtually. iEducate engages student mentors from the nearby University of Houston education program and graduating Alief ISD high school students to work alongside teachers to ensure that every child has the academic support needed to achieve their full potential.

"We are building on our unique range of educational support services that we have provided over the past to help schools advance student learning in these uncertain times," says Arun Gir, CEO of iEducate.

Gir says the coronavirus pandemic and the subsequent school closings have forced iEducate to adapt, just like many other teachers and educators. For the first time, they are offering a needs assessment to any school that is interested in working with them. Click here to read more.

Houston-based iEducate is connecting local tutors and mentors to students. Photo by Julia M Cameron from Pexels

Houston-area education platform looking for new schools to help teachers with online tools

online education

A Houston-based nonprofit mentorship program that matches underperforming second to fifth graders with college student tutors to provide them targeted support has adapted to the online schooling era, by introducing hybrid learning services in partnership with Texas Region 4 Education Service Center.

iEducate engages student mentors from the nearby University of Houston education program and graduating Alief ISD high school students to work alongside teachers to ensure that every child has the academic support needed to achieve their full potential.

"Before the pandemic closed schools, our vision was to have an in-person system mixing public institutions with our local community," says Arun Gir, CEO of iEducate. "Mentors could provide their math, science, and literacy skills to prove targeted support to students, encouraging teachers to differentiate learning by identifying groups that could benefit the most from our help."

"We are building on our unique range of educational support services that we have provided over the past to help schools advance student learning in these uncertain times," says Gir.

With their recently announced partnership with the Texas Region 4 Education Service Center, they will be able to train mentors on instructional tools and strategies to support any type of instruction including in-person, remote, and hybrid instruction.

"We are excited to collaborate with iEducate," says Pam Wells, executive director of Region 4 Education Service Center. "Their transformational work confirms the value that iEducate brings along with their ability to adapt and respond to our evolving educational needs."

The nonprofit, which was founded in 2013, started off as a hobby with Gir and volunteers working directly with individual schools, but after a few years, he left his job to work on building iEducate.

"Our focus is definitely on closing that achievement gap," says Gir. "One of our biggest issues is the literacy gap because that's a precursor to any type of student achievement beyond the early years. Personalized instruction focused on getting the portion of the class that is behind has led to growth for the students."

This summer, they conducted a needs assessment and revamped their mentorship program for a virtual classroom's needs, including calling out for more mentors. More than 600 applicants answered the call, ready to support over 7,000 students during the 2020-2021 school year.

"There was an overwhelming need for new types of assistance," says Gir. "From helping parents learn how to use online digital learning platforms to one-on-one tutoring and group tutoring sessions in the evening for students and parents, our mentors are willing and able and they have risen to the challenge."

To learn more about working with iEducate, email contact@iEducateUSA.org.

"We are navigating unexplored waters," says Gir. "We thought about opening up any school in the Houston area because we know that COVID-19 response measures are very decentralized which means we have to go directly to the source."

Ad Placement 300x100

Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

View All Listings

INNOVATIONMAP EMAILS ARE AWESOME