This week's innovators to know in Houston includes Tim Neal of GoExpedi, Shay Curran of UH, and Arun Gir of iEducate. Photos courtesy

Editor's note: In today's Monday roundup of Houston innovators, I'm introducing you to three gentlemen representing a diverse set of industries — from nanotech and higher education to industrial e-commerce and education.

Tim Neal, CEO of GoExpedi

Tim Neal, CEO of Houston-based GoExpedi, shares how his company plans to scale following its recent series C closing. Photo by Colt Melrose for GoExpedi

Timing is everything, and Tim Neal says it's been a key factor in his company's success. GoExpedi acts as an Amazon of industrial business, basically. Just as the e-commerce platform has made online ordering easy, trackable, and fast, so has GoExpedi for industrial parts. And, thanks to companies like Amazon and on-demand ordering in general, this type of fast and reliable service is what everyone expects now.

"The labor pool in the oil and gas space in particular — 50 percent of it turn it over. Now you're no longer having these tradesmen who are 60-plus years old and walking encyclopedias. You have a younger workforce that's used to buying on eCommerce and their daily life. So, it's helping them by technical parts in a not technical way," Neal says in a Q&A with InnovationMap. "We just had a pool of clients who were more tech native and who had more familiarity with transacting online." Click here to read more.

Seamus Curran, CEO and founder of Integricote

University of Houston professor and entrepreneur, Seamus Curran, has pivoted amid the pandemic to use his nanotechnology expertise to help reduce the spread of COVID-19. Photo courtesy of Integricote

Seamus Curran's life went from juggling teaching, research, and running his startup from early morning to late at night every day to working and teaching from home when the pandemic hit. He started looking into the virus and realized his nanotechnology actually has a real application in protecting people. First, he started coating masks. Lately he's been working on a new line of protection.

"The big thing for me when we were shut down was that people couldn't go to work or school. The country can't live that way — but you can't send people back to work in a world that's not safe," Curran says in this week's episode of the Houston Innovators Podcast. "How do you create a safer environment? That's the thing that really got me going in the beginning in the summer. We looked at filters." Click here to read more and stream the episode.

Arun Gir, CEO of iEducate

Houston-based iEducate is connecting local tutors and mentors to students. Photo courtesy of iEducate

Now more than ever, young students need hands-on instruction to keep up in their studies, which for so many still are being conducted virtually. iEducate engages student mentors from the nearby University of Houston education program and graduating Alief ISD high school students to work alongside teachers to ensure that every child has the academic support needed to achieve their full potential.

"We are building on our unique range of educational support services that we have provided over the past to help schools advance student learning in these uncertain times," says Arun Gir, CEO of iEducate.

Gir says the coronavirus pandemic and the subsequent school closings have forced iEducate to adapt, just like many other teachers and educators. For the first time, they are offering a needs assessment to any school that is interested in working with them. Click here to read more.

Houston-based iEducate is connecting local tutors and mentors to students. Photo by Julia M Cameron from Pexels

Houston-area education platform looking for new schools to help teachers with online tools

online education

A Houston-based nonprofit mentorship program that matches underperforming second to fifth graders with college student tutors to provide them targeted support has adapted to the online schooling era, by introducing hybrid learning services in partnership with Texas Region 4 Education Service Center.

iEducate engages student mentors from the nearby University of Houston education program and graduating Alief ISD high school students to work alongside teachers to ensure that every child has the academic support needed to achieve their full potential.

"Before the pandemic closed schools, our vision was to have an in-person system mixing public institutions with our local community," says Arun Gir, CEO of iEducate. "Mentors could provide their math, science, and literacy skills to prove targeted support to students, encouraging teachers to differentiate learning by identifying groups that could benefit the most from our help."

Gir says the coronavirus pandemic and the subsequent school closings have forced iEducate to adapt, just like many other teachers and educators. For the first time, they are offering a needs assessment to any school that is interested in working with them.

"We are building on our unique range of educational support services that we have provided over the past to help schools advance student learning in these uncertain times," says Gir.

With their recently announced partnership with the Texas Region 4 Education Service Center, they will be able to train mentors on instructional tools and strategies to support any type of instruction including in-person, remote, and hybrid instruction.

"We are excited to collaborate with iEducate," says Pam Wells, executive director of Region 4 Education Service Center. "Their transformational work confirms the value that iEducate brings along with their ability to adapt and respond to our evolving educational needs."

The nonprofit, which was founded in 2013, started off as a hobby with Gir and volunteers working directly with individual schools, but after a few years, he left his job to work on building iEducate.

"Our focus is definitely on closing that achievement gap," says Gir. "One of our biggest issues is the literacy gap because that's a precursor to any type of student achievement beyond the early years. Personalized instruction focused on getting the portion of the class that is behind has led to growth for the students."

This summer, they conducted a needs assessment and revamped their mentorship program for a virtual classroom's needs, including calling out for more mentors. More than 600 applicants answered the call, ready to support over 7,000 students during the 2020-2021 school year.

"There was an overwhelming need for new types of assistance," says Gir. "From helping parents learn how to use online digital learning platforms to one-on-one tutoring and group tutoring sessions in the evening for students and parents, our mentors are willing and able and they have risen to the challenge."

To learn more about working with iEducate, email contact@iEducateUSA.org.

"We are navigating unexplored waters," says Gir. "We thought about opening up any school in the Houston area because we know that COVID-19 response measures are very decentralized which means we have to go directly to the source."

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.