The most at-risk areas are in poorer industrial parts of Houston. Getty Images

A group of researchers from the University of Texas and the University of Houston have created a mapping tool for identifying which parts of the greater Houston area are at the greatest risk from COVID-19.

"The map offers a comparative look at vulnerabilities across Harris County, and could help policy makers determine how to allocate coronavirus tests and health and safety resources," says Amin Kiaghadi, a research associate at UT's Oden Institute for Computational Engineering & Sciences and postdoctoral fellow at the University of Houston, in a news release.

The study, which is posted on MedRxiv, looked into access to health care, pollutant exposure, and medical insurance coverage. Kiaghadi and two UH professors, Hanadi Rifai and Winston Liaw, concluded that the areas most at risk were in the east and northeastern parts of town — especially industrial areas and high-traffic waterways.

The research showed that the highest risk areas were identified as poorer communities, like the area near the Houston Ship Channel. Consequently, populations with lower risk are in the far west areas of Harris County, which tend to be considered nicer areas. According to the release, around 17 percent of the county's population falls into a risk category.

"I'm really interested to see how decision makers look at these maps," Kiaghadi continues. "They can say 'this specific area is vulnerable to many different things—people living there have lower income, they have or they don't have access to the medical care— and that can change the way that they distribute the resources."

Kiaghadi usually focuses on floodwaters spread contamination, and he postulates that his work in this field had an application within the pandemic.

"We believe that if you're exposed to some chemicals for a long time or you were living in an area with bad air quality, that can affect your immune system long term and then make you more vulnerable to a disease like COVID-19," Kiaghadi says. "So we decided to take a new approach here and show that these factors should be considered."

Based on census data, the map is divided up into 786 polygons and looks into 46 different variables in five categories:

  1. People with limited access to hospitals and medical care.
  2. People with underlying medical conditions.
  3. People with exposures to environmental pollutants.
  4. People in areas vulnerable to natural disasters and flooding.
  5. People with specific lifestyle factors, like obesity, drinking and smoking.

According to the release, the researchers formulated the map within just a couple weeks.

"We already had a lot of knowledge and experience working with this sociodemographic data, and population vulnerability to the flaws in the environment and exposure," Kiaghadi says. "So we felt like, this is totally related to our research, so why not explore what it means?"

The map is broken down by 786 census tracts. Graphic via utexas.edu

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Houston biopharma company launches equity crowdfunding campaign

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A clinical-stage company headquartered in Houston has opened an online funding campaign.

FibroBiologics, which is developing fibroblast cell-based therapeutics for chronic diseases, launched a campaign with equity crowdfunding platform StartEngine. The platform lets anyone — regardless of their net worth or income level — to invest in securities issued by startups.

The funding, according to a press release, will be used to support ongoing operations of Fibrobiologics and advance its clinical programs in multiple sclerosis, degenerative disc disease, wound care, extension of life, and cancer.

"We're excited to partner with StartEngine on this campaign. StartEngine has over 600,000 investors as part of their community and has raised over half a billion dollars for its clients," says FibroBiologics' Founder and CEO Pete O'Heeron, in the release.

"This is an exciting time at FibroBiologics as we continue progressing our clinical pipeline and developing innovative therapies to treat chronic diseases," he continues. "This new funding will fuel our growth in the lab and bring us one step closer to commercialization."

The campaign, launched this week, already has over 100 investors, at the time of publication, and has raised nearly $2 million, according to the page. The minimum investment is set at around $500, and the company's indicated valuation is $252.57 million.

In 2021, FibroBiologics announced its intention of going public. Last year, O'Heeron told InnovationMap on the Houston Innovators Podcast of the company's growth plans as well as the specifics of the technology.

Only two types of cells — stem cells and fibroblasts — can be used in cell therapy for a regenerative treatment, which is when specialists take healthy cells from a patient and inject them into a part of the body that needs it the most. As O'Heeron explains in the podcast, fibroblasts can do it more effectively and cheaper than stem cells.

"(Fibroblasts) can essentially do everything a stem cell can do, only they can do it better," says O'Heeron. "We've done tests in the lab and we've seen them outperform stem cells by a low of 50 percent to a high of about 220 percent on different disease paths."


Texas ranks as a top state for female entrepreneurs

women in business

Texas dropped three spots in Merchant Maverick’s annual ranking of the top 10 states for women-led startups.

The Lone Star State landed at No. 5 thanks in part to its robust venture capital environment for women entrepreneurs. Last year, Texas ranked second, up from its No. 6 showing in 2021.

Merchant Maverick, a product comparison site for small businesses, says Texas “boasts the strongest venture capital scene” for women entrepreneurs outside California and the Northeast. The state ranked fourth in that category, with $6.5 billion invested in the past five years.

Other factors favoring Texas include:

  • Women solely lead 22 percent of all employees working for a business in Texas (No. 4).
  • Texas lacks a state income tax (tied for No. 1).

However, Texas didn’t fare well in terms of the unemployment rate (No. 36) and the rate of business ownership by women (No. 29). Other Texas data includes:

  • Average income for women business owners, $52,059 (No. 19).
  • Early startup survival rate, 81.9 percent (No. 18).

Appearing ahead of Texas in the 2023 ranking are No. 1 Colorado, No. 2 Washington, No. 3 California, and No. 4 Arizona.

Another recent ranking, this one from NorthOne, an online bank catering to small businesses, puts Texas at No. 7 among the 10 best states for women entrepreneurs.

NorthOne says Texas provides “a ton of opportunities” for woman entrepreneurs. For instance, it notches one of the highest numbers of women-owned businesses in the country at 1.4 million, 2.1 percent of which have at least 500 employees.

In this study, Texas is preceded by Colorado at No. 1, Nevada at No. 2, Virginia at No. 3, Maryland at No. 4, Florida at No. 5, and New Mexico at No. 6. The rankings are based on eight metrics, including the percentage of woman-owned businesses and the percentage of women-owned businesses with at least 500 employees.