This week's Houston innovators to know roundup includes Aimee Woodall of The Black Sheep Agency, Alok Pant of Unvired, and Abbey Donnell of Work & Mother. Photos courtesy

Houston's rising COVID-19 case numbers and Texas' new regulations for bars and restaurants are a sure sign that the city isn't out of the woods from the pandemic — and that includes Houston's startups and entrepreneurs.

This week's three Houston innovators to know include three people who are advocating for continuing through the pandemic — the right way, from using tech to better communicate with employees at home to factoring in the new moms when you roll out your back-to-work plans.

Aimee Woodall, CEO and founder of the Black Sheep Agency

Aimee Woodall has been focused on innovation and creativity during COVID-19 for her own company, The Black Sheep Agency, but also for its clients. Photo courtesy of The Black Sheep Agency

Aimee Woodall founded The Black Sheep Agency in order to help impact-based businesses tell their stories. Now, amid COVID-19, that mission is more important than ever.

"We write, we design, we build campaigns, we work in the digital space — whatever it takes to tell the story of the organization and to rally other people to not only pay attention to what the organization is doing but to also find their own way to participate in moving that mission forward," Woodall shares on this week's episode of the Houston Innovators Podcast.

Thinking back to when COVID-19 really started affecting business and her campaigns, Woodall remembers how she and her team had to reevaluate existing content, pivot planned projects, and, in some cases, cancel events or programming. Read more.

Alok Pant, founder and CEO of Unvired

A Houston software startup has created a communication tool and is allowing free access amid the COVID-19 pandemic. Photo courtesy of Unvired

A Houston startup recently released an app to help employees voice their concerns and keep businesses with their finger on the pulse of employee morale. The survey is customizable for each business and contains questions with the most important factors such as employee health and well being, communication, confidence, and leadership.

"Digital Forms fits in with a whole new paradigm in the software world," says Alok Pant, CEO of Unvired. "It allows a business user to make their own specialized applications fast and easy with no coding necessary."

The low-code platform has a drag-and-drop form building feature to instantly deploy surveys, can store data in the Unvired Cloud, and instantly generate reports for insights in the administration portal. Read more.

Abbey Donnell, founder of Work & Mother

Abbey Donnell's startup, Work & Mother, provides a new way for new moms to pump breast milk during the workday. Courtesy of Work & Mother

As offices started to reopen and release new safety measures that will be put in place in the office, Abbey Donnell noticed a certain group or people who were going to be affected by these measures: New moms. Mother's rooms are usually multi purposeful, lack access to sinks, and seen as expendable, Donnell writes in a guest column for InnovationMap,

"If mother's needs are not part of this vital return to work safety conversation, women may be left behind," she writes. "So let's start the conversation." Read more.

A Houston software startup has created a communication tool and is allowing free access amid the COVID-19 pandemic. Getty Images

Houston tech startup offers free survey app to help companies manage COVID-19 response

software solutions

Keeping employees and employers connected is crucial during a crisis. A Houston-based software startup recognizes the importance of communication during the COVID-19 pandemic, providing its digital form and surveys app for free for six months.

Unvired Inc. recently unveiled its Digital Forms app to help employees voice their concerns and keep businesses with their finger on the pulse of employee morale. The survey is customizable for each business and contains questions with the most important factors such as employee health and well being, communication, confidence, and leadership.

"Digital Forms fits in with a whole new paradigm in the software world," says CEO Alok Pant. "It allows a business user to make their own specialized applications fast and easy with no coding necessary."

The low-code platform has a drag-and-drop form building feature to instantly deploy surveys, can store data in the Unvired Cloud, and instantly generate reports for insights in the administration portal.

The startup already has customers using it for their COVID-19 response, with users choosing to use it as a sort of information hub with frequently asked questions along with questions regarding employee and health wellbeing. While other companies use for surveying the number of masks and hand sanitizer supplies available.

The forms app, already in the works months before the virus changed the scope of daily life, will be officially launched in July.

"Digital Forms inadvertently became the perfect tool to easily build forms and create workflows during the time of the coronavirus pandemic," says Pant. "We wanted to help our community in any small way we can, so we saw offering this app for free as a great opportunity to help our business community."

Unvired, which is based out of Station Houston, has nationwide and international clients in a variety of different industries. According to Pant, Unvired's platform for surveys and customizable forms was first born out of their own customer's need for an app with form digitization capabilities.

"Many of our customers, especially in the oil field use many paper forms as part of their process," says Plant. "Our app is a very form-centric application that can serve our customers with automated digitization of forms, making it easier for employees to reduce manual data entry, enable real-time decision making, and lower operational costs."

This launch is only part of Unvired's new line of products. The startup is also releasing Chyme Bots, a digital communications solution that can be tailored to a specific business to answer frequently asked questions quickly and remotely.

"Many businesses will have to start to invest in digital in the near future," says Pant. "If they want to get out of the slump the pandemic has landed many businesses, digitization along with digital applications will be key to growth and efficiency."

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.