This week's Houston innovators to know roundup includes Aimee Woodall of The Black Sheep Agency, Alok Pant of Unvired, and Abbey Donnell of Work & Mother. Photos courtesy

Houston's rising COVID-19 case numbers and Texas' new regulations for bars and restaurants are a sure sign that the city isn't out of the woods from the pandemic — and that includes Houston's startups and entrepreneurs.

This week's three Houston innovators to know include three people who are advocating for continuing through the pandemic — the right way, from using tech to better communicate with employees at home to factoring in the new moms when you roll out your back-to-work plans.

Aimee Woodall, CEO and founder of the Black Sheep Agency

Aimee Woodall has been focused on innovation and creativity during COVID-19 for her own company, The Black Sheep Agency, but also for its clients. Photo courtesy of The Black Sheep Agency

Aimee Woodall founded The Black Sheep Agency in order to help impact-based businesses tell their stories. Now, amid COVID-19, that mission is more important than ever.

"We write, we design, we build campaigns, we work in the digital space — whatever it takes to tell the story of the organization and to rally other people to not only pay attention to what the organization is doing but to also find their own way to participate in moving that mission forward," Woodall shares on this week's episode of the Houston Innovators Podcast.

Thinking back to when COVID-19 really started affecting business and her campaigns, Woodall remembers how she and her team had to reevaluate existing content, pivot planned projects, and, in some cases, cancel events or programming. Read more.

Alok Pant, founder and CEO of Unvired

A Houston software startup has created a communication tool and is allowing free access amid the COVID-19 pandemic. Photo courtesy of Unvired

A Houston startup recently released an app to help employees voice their concerns and keep businesses with their finger on the pulse of employee morale. The survey is customizable for each business and contains questions with the most important factors such as employee health and well being, communication, confidence, and leadership.

"Digital Forms fits in with a whole new paradigm in the software world," says Alok Pant, CEO of Unvired. "It allows a business user to make their own specialized applications fast and easy with no coding necessary."

The low-code platform has a drag-and-drop form building feature to instantly deploy surveys, can store data in the Unvired Cloud, and instantly generate reports for insights in the administration portal. Read more.

Abbey Donnell, founder of Work & Mother

Abbey Donnell's startup, Work & Mother, provides a new way for new moms to pump breast milk during the workday. Courtesy of Work & Mother

As offices started to reopen and release new safety measures that will be put in place in the office, Abbey Donnell noticed a certain group or people who were going to be affected by these measures: New moms. Mother's rooms are usually multi purposeful, lack access to sinks, and seen as expendable, Donnell writes in a guest column for InnovationMap,

"If mother's needs are not part of this vital return to work safety conversation, women may be left behind," she writes. "So let's start the conversation." Read more.

A Houston software startup has created a communication tool and is allowing free access amid the COVID-19 pandemic. Getty Images

Houston tech startup offers free survey app to help companies manage COVID-19 response

software solutions

Keeping employees and employers connected is crucial during a crisis. A Houston-based software startup recognizes the importance of communication during the COVID-19 pandemic, providing its digital form and surveys app for free for six months.

Unvired Inc. recently unveiled its Digital Forms app to help employees voice their concerns and keep businesses with their finger on the pulse of employee morale. The survey is customizable for each business and contains questions with the most important factors such as employee health and well being, communication, confidence, and leadership.

"Digital Forms fits in with a whole new paradigm in the software world," says CEO Alok Pant. "It allows a business user to make their own specialized applications fast and easy with no coding necessary."

The low-code platform has a drag-and-drop form building feature to instantly deploy surveys, can store data in the Unvired Cloud, and instantly generate reports for insights in the administration portal.

The startup already has customers using it for their COVID-19 response, with users choosing to use it as a sort of information hub with frequently asked questions along with questions regarding employee and health wellbeing. While other companies use for surveying the number of masks and hand sanitizer supplies available.

The forms app, already in the works months before the virus changed the scope of daily life, will be officially launched in July.

"Digital Forms inadvertently became the perfect tool to easily build forms and create workflows during the time of the coronavirus pandemic," says Pant. "We wanted to help our community in any small way we can, so we saw offering this app for free as a great opportunity to help our business community."

Unvired, which is based out of Station Houston, has nationwide and international clients in a variety of different industries. According to Pant, Unvired's platform for surveys and customizable forms was first born out of their own customer's need for an app with form digitization capabilities.

"Many of our customers, especially in the oil field use many paper forms as part of their process," says Plant. "Our app is a very form-centric application that can serve our customers with automated digitization of forms, making it easier for employees to reduce manual data entry, enable real-time decision making, and lower operational costs."

This launch is only part of Unvired's new line of products. The startup is also releasing Chyme Bots, a digital communications solution that can be tailored to a specific business to answer frequently asked questions quickly and remotely.

"Many businesses will have to start to invest in digital in the near future," says Pant. "If they want to get out of the slump the pandemic has landed many businesses, digitization along with digital applications will be key to growth and efficiency."

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”