3 Houston innovators to know this week

who's who

This week's Houston innovators to know roundup includes Aimee Woodall of The Black Sheep Agency, Alok Pant of Unvired, and Abbey Donnell of Work & Mother. Photos courtesy

Houston's rising COVID-19 case numbers and Texas' new regulations for bars and restaurants are a sure sign that the city isn't out of the woods from the pandemic — and that includes Houston's startups and entrepreneurs.

This week's three Houston innovators to know include three people who are advocating for continuing through the pandemic — the right way, from using tech to better communicate with employees at home to factoring in the new moms when you roll out your back-to-work plans.

Aimee Woodall, CEO and founder of the Black Sheep Agency

Aimee Woodall has been focused on innovation and creativity during COVID-19 for her own company, The Black Sheep Agency, but also for its clients. Photo courtesy of The Black Sheep Agency

Aimee Woodall founded The Black Sheep Agency in order to help impact-based businesses tell their stories. Now, amid COVID-19, that mission is more important than ever.

"We write, we design, we build campaigns, we work in the digital space — whatever it takes to tell the story of the organization and to rally other people to not only pay attention to what the organization is doing but to also find their own way to participate in moving that mission forward," Woodall shares on this week's episode of the Houston Innovators Podcast.

Thinking back to when COVID-19 really started affecting business and her campaigns, Woodall remembers how she and her team had to reevaluate existing content, pivot planned projects, and, in some cases, cancel events or programming. Read more.

Alok Pant, founder and CEO of Unvired

A Houston software startup has created a communication tool and is allowing free access amid the COVID-19 pandemic. Photo courtesy of Unvired

A Houston startup recently released an app to help employees voice their concerns and keep businesses with their finger on the pulse of employee morale. The survey is customizable for each business and contains questions with the most important factors such as employee health and well being, communication, confidence, and leadership.

"Digital Forms fits in with a whole new paradigm in the software world," says Alok Pant, CEO of Unvired. "It allows a business user to make their own specialized applications fast and easy with no coding necessary."

The low-code platform has a drag-and-drop form building feature to instantly deploy surveys, can store data in the Unvired Cloud, and instantly generate reports for insights in the administration portal. Read more.

Abbey Donnell, founder of Work & Mother

Abbey Donnell's startup, Work & Mother, provides a new way for new moms to pump breast milk during the workday. Courtesy of Work & Mother

As offices started to reopen and release new safety measures that will be put in place in the office, Abbey Donnell noticed a certain group or people who were going to be affected by these measures: New moms. Mother's rooms are usually multi purposeful, lack access to sinks, and seen as expendable, Donnell writes in a guest column for InnovationMap,

"If mother's needs are not part of this vital return to work safety conversation, women may be left behind," she writes. "So let's start the conversation." Read more.

A Houston software startup has created a communication tool and is allowing free access amid the COVID-19 pandemic. Getty Images

Houston tech startup offers free survey app to help companies manage COVID-19 response

software solutions

Keeping employees and employers connected is crucial during a crisis. A Houston-based software startup recognizes the importance of communication during the COVID-19 pandemic, providing its digital form and surveys app for free for six months.

Unvired Inc. recently unveiled its Digital Forms app to help employees voice their concerns and keep businesses with their finger on the pulse of employee morale. The survey is customizable for each business and contains questions with the most important factors such as employee health and well being, communication, confidence, and leadership.

"Digital Forms fits in with a whole new paradigm in the software world," says CEO Alok Pant. "It allows a business user to make their own specialized applications fast and easy with no coding necessary."

The low-code platform has a drag-and-drop form building feature to instantly deploy surveys, can store data in the Unvired Cloud, and instantly generate reports for insights in the administration portal.

The startup already has customers using it for their COVID-19 response, with users choosing to use it as a sort of information hub with frequently asked questions along with questions regarding employee and health wellbeing. While other companies use for surveying the number of masks and hand sanitizer supplies available.

The forms app, already in the works months before the virus changed the scope of daily life, will be officially launched in July.

"Digital Forms inadvertently became the perfect tool to easily build forms and create workflows during the time of the coronavirus pandemic," says Pant. "We wanted to help our community in any small way we can, so we saw offering this app for free as a great opportunity to help our business community."

Unvired, which is based out of Station Houston, has nationwide and international clients in a variety of different industries. According to Pant, Unvired's platform for surveys and customizable forms was first born out of their own customer's need for an app with form digitization capabilities.

"Many of our customers, especially in the oil field use many paper forms as part of their process," says Plant. "Our app is a very form-centric application that can serve our customers with automated digitization of forms, making it easier for employees to reduce manual data entry, enable real-time decision making, and lower operational costs."

This launch is only part of Unvired's new line of products. The startup is also releasing Chyme Bots, a digital communications solution that can be tailored to a specific business to answer frequently asked questions quickly and remotely.

"Many businesses will have to start to invest in digital in the near future," says Pant. "If they want to get out of the slump the pandemic has landed many businesses, digitization along with digital applications will be key to growth and efficiency."

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Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.

5 incubators and accelerators fueling the growth of Houston startups

meet the finalists

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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Rice University launches  engineering-led brain science and health institute

brain research

Rice University has announced the creation of a new interdisciplinary center known as the Rice Brain Institute (RBI).

The new hub will aim to use engineering, natural sciences and social sciences to research the brain and reduce the burden of neurodegenerative, neurodevelopmental and mental health disorders.

“The Rice Brain Institute reflects Rice’s strength in collaboration without boundaries,” Rachel Kimbro, dean of the School of Social Sciences, said in a news release. “Our researchers are not only advancing fundamental science but they’re also ensuring that knowledge reaches society in ways that promote human flourishing.”

RBI researchers will work in thematic clusters focusing on neurodegeneration, mental health, brain injury and neurodevelopment. The clusters will work toward goals such as significantly improving key brain health outcomes, reducing mortality and mental health disorders and improving quality of life for patients living with brain injuries and neurodevelopmental disorders, according to Rice.

The institute will focus on “engineering-driven innovation,” rather than traditional neuroscience, to design tools that can measure, model and modulate brain activity based around Rice’s expertise in soft robotics, neuroimaging, data science and artificial intelligence—making it unique among peer organizations, according to Rice.

Additionally, RBI will be structured around three collaborative Rice “pillars”:

  • The Neuroengineering Initiative, launched in 2018, brings together neuroscience, engineering, and related fields experts
  • The Neuroscience Initiative, a new initiative that brings together cell biologists, neurobiologists, biochemists, chemists and physicists to explore fundamental mechanisms of the brain and nervous system
  • The Brain and Society Initiative, also a new initiative, considers brain research within the broader social and policy landscape

Rice’s Neuroengineering Initiative has already garnered more than $78 million in research funding, according to Rice, and has established major partnerships, like the Rice-Houston Methodist Center for Neural Systems Restoration.

“Rice is uniquely equipped to bridge and connect scientific understanding of the brain and behavior sciences with the technologies and policies that shape our world,” Amy Dittmar, the Howard R. Hughes Provost and executive vice president for academic affairs, added in the news release. “By uniting faculty in neuroengineering, neuroscience and psychological sciences, this interdisciplinary hub embodies the kind of bold, nimble collaboration that allows Rice to turn discovery into societal impact to save lives and enhance human flourishing.”

The formation of the RBI coincides with recent support of the Dementia Prevention Research Institute of Texas (DPRIT), which landed voter approval earlier this week and aims to make Texas the center for dementia research via brain-health tech. According to the World Economic Forum, brain disorders and mental health disorders cost the global economy an estimated $5 trillion per year and could be as high as $16 trillion by 2030.

“Few areas of research have as direct and profound an impact on human well-being as brain health,” Rice President Reginald DesRoches added in the news release. “As rates of Alzheimer’s, dementia and other neurological diseases rise in our country and around the world, universities have a responsibility to lead the discovery of solutions that preserve memory, movement and quality of life. We all know someone who has been affected by a brain-related health issue, so this research is personal to all of us.”

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