Jan E. Odegard, Deanea LeFlore, and Chris Valka have been named senior directors at The Ion. Photos courtesy of The Ion

The Ion, an entrepreneurship center being developed in the old Sears building in Midtown by the Rice Management Company, has named three new senior directors to its team.

Deanea LeFlore, Jan E. Odegard, and Chris Valka are the three newly named leaders of the organization, effective immediately. They join — and will report to — Gabriella Rowe, who was named executive director in October.

"To grow the Houston innovation system and spearhead our mission for the Ion we've hired three new leaders with fresh perspectives, ideas, and approaches," says Allison K. Thacker, president and chief investment officer of the Rice Management Company, in a news release. "Each individual has a unique connection to Houston and the Ion, and we're thrilled to have them join our effort to build on the culture of innovation across our city, and within the community we're cultivating at the Ion."

To focus on the Ion's Academic Partner Network, Jan E. Odegard has been appointed senior director of industry and academic partners. Odegard's background includes research and leadership at Rice University in computing. Odegard will also oversee The Ion's labs, which include human/robotics interaction lab, an immersive reality lab and an industrial prototyping lab.

Deanea LeFlore has been named senior director of community and corporate engagement. Like Rowe, LeFlore had a similar role at Station Houston before this new position. Before that, she spent most of her career working for the city of Houston and served under four Mayors over 17 years.

Lastly, Chris Valka, has been hired as senior director of operations, overseeing finance, accounting, human resources, operations, and facilities management. Prior to this position, Valka served in the president's cabinet overseeing a similar spectrum of responsibilities at the University of St. Thomas.

"As we prepare for The Ion's opening in early 2021, we are excited to welcome Deanea LeFlore, Dr. Jan E. Odegard, and Chris Valka, to our growing team," says Rowe in the release. "I am excited to see what this diverse group of experts will bring to our efforts to build an inclusive innovation hub in a tech-forward environment that promotes all that is great about Houston."

The 270,000-square-foot Ion building broke ground in July of last year and is slated to open in 2021. Recently, the organization announced its first programming partner — Rice University's Glasscock School of Continuing Studies, and select courses have already begun.

From M&A action to the development of Houston's innovation corridor, these are five Houston innovators to keep an eye on in 2020. Courtesy photos

5 Houston innovators to know in 2020

Who's who

For so many Houston innovators, 2020 will be a year of growth, execution, proof of concept, piloting, pivoting, fundraising, and more.

It's hard to narrow down the list of movers and shakers in Houston innovation, but a few have stood out for making waves in the new year. From M&A action to the development of Houston's innovation corridor, these are five Houston innovators to keep an eye on in 2020.

Rakesh Agrawal, founder and CEO of SnapStream

Photo courtesy of SnapStream

This past year has been good to SnapStream, but it's only the beginning of the company's next growth phase. The software company's technology allows its clients to easily record, search, and share video and broadcast content and has attracted clients from the likes of Saturday Night Live and Last Week Tonight.

In 2019, the company was named the transition partner for Volicon Observer, a company Verizon brought under its umbrella and then changed its mind about, Rakesh Agrawal, CEO of SnapStream, explains on an episode of the Houston Innovators Podcast. Volicon's specialty is in monitoring and compliance, and with that move, SnapStream brought on around 150 new clients. To maintain those clients and grow its services, SnapStream has rolled out a whole new department. The launch of SnapStream Monitoring and Compliance is the next step for SnapStream's takeover of Volicon, according to a news release.

The M&A activity sparked a move to hire and expand the SnapStream team as the division grows throughout 2020.

Allison Thacker, president of the Rice Management Company

Natalie Harms/InnovationMap

Houston has its eyes on The Ion, a 270,000-square-foot building innovation center being developed in the former Sears building in Midtown. Behind the project is the Rice Management Company, which is led by Allison Thacker, president of the organization.

The Ion broke ground in May, and also named its operations leader, Gabriella Rowe, CEO of Station Houston earlier this year. While the project isn't expected to deliver until 2021, next year will likely entail determining a few key things about The Ion and the surrounding innovation corridor Rice Management and the city will be developing.

The Houston Coalition for Equitable Development without Displacement, a newly formed organization, has recently expressed its concerns with the development of the property in the historic Third Ward. The community organization wants Rice Management and all parties involved with the innovation corridor to agree to a Community Benefits Agreement, which would protect local residents and provide positive initiatives for growth. The CBA is expected to be arranged in 2020 as the project moves forward.

Andrew Bruce, founder and CEO of Data Gumbo

Photo courtesy of Data Gumbo

Another Houston company that plans to grow throughout 2020 is Data Gumbo. The blockchain-as-a-service company has raised some significant funds — a $6 million series A round closed in May — and will be putting that money to work by expanding the company's footprint and services.

Earlier this year, the company announced its entrance into the construction industry — Andrew Bruce, CEO of Data Gumbo, says in a recent episode of the Houston Innovators Podcast that the funds will also take Data Gumbo to new global markets, including the Middle East.

"The whole thing for us is building this blockchain network of interconnected companies," Bruce says. "The more companies that are a part of that network, the more value that network has."

Payal Patel, director of corporate partnerships at Plug and Play Tech Center in Houston

Courtesy of Payal Patel

San Francisco-based Plug and Play Tech Center quickly established its new energy-focused Houston location — from announcing its entrance into the market in June to hiring its director of corporate partnerships, Payal Patel, in September. The first cohort of portfolio companies were named in October, and several new Houston partner corporations have been announced as well.

Next year, the local team is expected to grow and is currently hiring for a few positions, as well as announce its office space in town. Patel, specifically, will spearhead the initiatives to grow the organizations already impressive list of corporate partners.

"[Plug and Play ha] great Fortune 500 corporate partners, they work and know the best tech startups all over the world, and they have a strong investment capability," Patel previously told InnovationMap. "I'm excited that those resources and capabilities are coming to Houston."

Travis Parigi, CEO of LiquidFrameworks

Courtesy of LiquidFrameworks

Travis Parigi has always been the one to write the code for his company's software technology, but now, he's in acquisition mode thanks to new support from private equity. Last January, LiquidFrameworks entered into a partnership with private equity firm, Luminate Capital. The new financial partner has opened doors for Parigi, CEO of LiquidFrameworks, and the company as a whole — including putting merger and acquisition activity on the table.

The company has grown its team and even moved to a bigger space in Greenway Plaza. LiquidFrameworks, which has created a suite of software solutions for upstream and downstream oil and gas companies called FieldFX, is also working on key updates and new features for its software.

The Rice Management Company has created a new operations organization for The Ion and has selected Gabriella Rowe to lead it. Courtesy of Rice University

Station Houston CEO to lead operations at The Ion

Eyes on the ion

A Houston innovation leader is switching sides of the table to support on a highly anticipated entrepreneurial hub.

Rice Management Company has created an operating organization for The Ion and has named Gabriella Rowe as the executive director. Rowe has served as CEO of Station Houston since August 2018. The Ion, which broke ground on the site of the Midtown Sears building in July, is expected to deliver early 2021.

"To ensure that The Ion is a catalyst for the continued growth of the innovation ecosystem, we've been collaborating with Gaby and her team as well as civic leaders, Mayor Sylvester Turner, Harris County commissioners and Midtown Houston," says Allison Thacker, president and chief investment officer of the RMC, in a news release. "We know that under Gaby's leadership The Ion will become an innovation hub for not only all Houstonians, but for anybody looking to thrive and collaborate in an entrepreneur-first, tech-forward environment."

Station was previously announced as The Ion's exclusive program partner, however that's no longer the case, according to the release. RMC plans to have a mix of incubators, accelerators, and startup development organizations within The Ion, and Station will be among that group. Per the release, an advisory board will formed to steer the innovation hub's programming.

"Collaboration is key to accelerating the growth of Houston's technology economy," says Harvin Moore, president of Houston Exponential, in the release. "The Ion will play an important role, serving the entire ecosystem as a place where those collaborations occur. Houston's incubators and accelerators, universities, corporations and venture capitalists will have a hub to leverage the innovation taking place all across the Houston region."

Station's newly named chief of staff, Stewart Cory, will oversee the organization until its new leader is named, and the nonprofit will focus on the needs of its startup entrepreneurs and growing its membership base, according to the release.

"It is a tremendous honor to be given such an incredible opportunity to serve Houston," Rowe says in the release. "I look forward to building partnerships and collaborations that will enable The Ion to engage and connect the innovation and startup community with Houston corporations and academic partners, to use the technology we're building right here in Houston to showcase our homegrown talent, and to create platforms for local entrepreneurs to take their offerings to new heights."

The Ion's early programming — like The Ion Smart Cities Accelerator, which launched last month — is being hosted out of Station's downtown location. According to the rease, The Ion expects to deliver more programming from its partner organizations — like the Houston Independent School District, the University of Houston, Houston Methodist, Pumps & Pipes and TXRX Labs — by early 2020.

The Ion is the first phase of the 16-acre South Main Innovation District the city is envisioning.

"The Ion, with Rice University's stewardship, represents the best of our vision for the future of Houston — one where a kid like me from Acres Homes grows up with access to the opportunities that innovation and technology represent," says Mayor Turner in the release. "I couldn't be happier that Gaby will be leading the Ion towards that vision and believe that she has the energy to help make this project a reality that will transform our communities."

------

Correction: Early information sent to InnovationMap reported that Rowe was leaving her position at Station, but she will maintain both roles, according to a representative at Station.

gaby roweGabriella Rowe will lead operations at The Ion.

The Rice Management Company has broken ground on the renovation of the historic Midtown Sears building, which will become The Ion. Natalie Harms/InnovationMap

Overheard: The Ion breaks ground in Midtown's former Sears building

Hard hats on

The Ion — a to-be entrepreneurial hub for startups, universities, tech companies, and more — is, in a way, the lemonade created from the lemons dealt to the city by a snub from Amazon.

In 2018, Amazon narrowed its options for a second headquarters to 20 cities, and Houston didn't make the shortlist.

"That disappointment lead to a sense of urgency, commitment, and imagination and out of that has come something better than we ever could have imagined," David Leebron, president of Rice University, says to a crowd gathered for The Ion's groundbreaking on July 19.

However disappointing the snub from Amazon was, it was a wake-up call for so many of the Houston innovation ecosystem players. The Ion, which is being constructed within the bones of the historic Midtown Sears building, is a part of a new era for the city.

"Houston's on a new course to a new destination," says Mayor Sylvester Turner.

Here are some other overheard quotes from the groundbreaking ceremony. The 270,000-square-foot building is expected to be completed in 18 months.


The historic Sears building in Midtown will transform into The Ion, a Rice University-backed hub for innovation. Courtesy of Rice University


The Sears opened in 1939. Natalie Harms/InnovationMap

“We have the capacity — if we work together — not only to make this a great innovation hub, but to do something that truly represents the Houston can-do, collaborative spirit.”

— David Leebron, president of Rice University. Leebron stressed the unique accomplishment the Ion has made to bring all the universities of Houston together for this project. "When we tell people the collaboration that has been brought together around this project, they are amazed," he says.

“The nation is seeing what we already know in the city of Houston. That this city has the greatest and most creative minds. We are a model for inclusion among people and cultures from everywhere. We are a city that taps the potential of every resident, dares them to dream big, and we provide the tools to make those dreams come true.”

— Mayor Sylvester Turner, who says he remembers shopping in the former Sears building as a kid, but notes how Houston's goals have changed, as has the world.

“When this store opened in 1939, it showcased a couple of innovations even back then: The first escalator in Texas, the first air conditioned department store in Houston, the first windowless department store in the country.”

— Senator Rodney Ellis, who adds the request that The Ion have windows.

“Many people ask us, ‘why not just tear down the old building and start new?’ We actually see this as a very unique opportunity for companies and entrepreneurs to be located within a historic building, while benefiting from an enhanced structure, state-of-the-art technology, and Class A tenant comforts.”

— Allison Thacker, president of the Rice Management Company. She describes the environment of being a beehive of activity.

“[As program partner for The Ion,] our mission is to build the innovation economy of Houston one entrepreneur at a time.”

— Gabriella Rowe, CEO of Station Houston. Rowe describes Station's role as a connector between startups, venture capital firms, major corporations, and more.

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CultureMap Emails are Awesome

7+ can't-miss Houston business and innovation events in June 2026

where to be

Editor's note: The FIFA World Cup comes to Houston this month, joined by major energy conferences and a lineup of fan-favorite, recurring events. Here’s what not to miss and how to register. Please note: this article may be updated to add more events.


June 1-4 — CLEANPOWER 2026 Conference and Exhibition

CLEANPOWER unites policymakers, experts, and corporate leaders to solve the challenges that none can solve alone. This must-attend, four-day conference is packed with cutting-edge discussions about wind, solar, storage, and transmission; dealmaking; networking; and fun.

This event begins June 1 at the George R. Brown Convention Center. Register here.

June 2 — Humans of Healthcare

Houston Methodist Center for Innovation will present its quarterly speaker series, Humans of Healthcare. The series will feature a panel of experts who will share about their career paths and discuss the nuances of the health care industry. This month's session will focus on today’s nursing landscape, the industry’s expectations of nurses and what career paths are possible in the field.

The event is Tuesday, June 2, from 5-6:30 p.m. at the Ion. Register here.

June 9 — Greentown Go Make Kickoff

Head to the Ion to celebrate the Greentown Go Make 2026 cohort. The open-innovation program with Shell Catalysts & Technologies and Technip Energies focuses on catalytic solutions for industrial decarbonization and the energy transition. Hear pitches from the founders and network with a select group of startups while enjoying food and drink.

This event is Tuesday, June 9, from 5:30-8 p.m. Register here.

June 9-10 — Texas Brain Economy Summit

The Center for Houston’s Future and UTMB are bringing the Texas Brain Economy Summit back to Houston this summer to continue to position the region as a global leader in brain health. Expect to hear from leaders of global institutions, including the World Economic Forum, U.S. Chamber of Commerce, McKinsey Health Institute, Global Brain Economy Initiative, Davos Alzheimer’s Collaborative, Business Collaborative for Brain Health (UsAgainstAlzheimer’s), Rice University, Memorial Hermann, MD Anderson and many others. Read InnovationMap's full preview of the event here.

This event begins Tuesday, June 9. Purchase tickets here.

June 10 — MIT Future of Healthcare Technology Forum

The MIT Club of South Texas will host an in-person forum to explore how innovation, government and policy are changing the healthcare industry. The event will feature MIT alumni and Houston healthcare leaders, including Dr. Tim Boone, dean of the Texas A&M School of Engineering Medicine; Cynthia Reinhart-King, chair of bioengineering at Rice University; Dr. Tony Lin, CEO and chairman emeritus of Kelsey-Seybold Clinic; and others.

This event is Wednesday, June 10, from 5:15-8:30 p.m. at the TAMU EnMed Building. Register here.

June 11 — Goals & Gigawatts: Houston Energy & Climate Week The Power of & Kickoff Party

Come watch the Mexico City FIFA opening match while celebrating energy and innovation at the Goals & Gigawatts Kickoff Party. The event will feature food, drinks, and a showcase on Houston Energy & Climate Week. Learn what to expect and how to get involved in HECW before closing the night with a DJ and karaoke.

This event is Thursday, June 11, from 1:30-6:30 p.m. Find more information here.

June 16-17 — Energy Projects Conference & Expo

The Energy Projects Conference & Expo (EPC Show) is the largest event in North America for professionals working at the heart of major energy projects. The essential event for engineering, construction, commissioning, operations and maintenance across multiple energy sectors brings together five leading conferences under one roof. Conference subjects span LNG exporting, hydrogen and ammonia, midstream, petrochem and refining, and sustainable aviation fuels.

This event begins June 16 at George R. Brown Convention Center. Register here.

June 25 – NASA Tech Talk

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing, and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, June 25, from 6-7 p.m. at the Ion. Register here.

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”