The Cannon Galveston @ the MarMo has opened as a convening space for Galveston entrepreneurship. Photo via TheCannon.com

The Cannon Houston has expanded its footprint throughout 2021, and one of the coworking company's newest hubs has opened its doors seaside.

The Cannon Galveston @ the MarMo is a new coworking space with membership options starting at $180 a month for entrepreneurs. The building is a former credit union space that Galveston real estate entrepreneur, Jimmy McClure, bought and renovated. McClure is also one of The Cannon's board members as of a couple months ago.

"We've always felt there was this opportunity to create this coastal innovation community," says Alex Gras, chief commercial officer at the Cannon. "And we found a great partner in Jimmy McClure."

In the aftermath of the pandemic, Gras says people are going to be more intentional about where they spend their time, and this location offers its member companies something different.

The new space has membership options starting at $180 a month. Image via TheCannon.com

"Not only does Galveston have the allure of a coastal town with a more relaxed atmosphere, but it has some amazing support organizations," he says.

Gras is referring to the numerous innovative institutions on the island that have been operating in silos over the years — including University of Texas Medical Branch at Galveston, Texas A&M Galveston, Galveston College, Galveston ISD, Vision Galveston, and more. Gras says the feedback for The Cannon providing this neutral convening space for entrepreneurship has been so positive.

"Galveston really has the raw ingredients to become an amazing innovation ecosystem," Gras tells InnovationMap.

From a programming perspective, entrepreneurs can expect exactly what The Cannon has brought to its other locations. The team recently held a hacakathon in collaboration with The Ion, Vision Galveston, and UTMB — which was a major success, according to Gras — and plans to host a pitch competition on March 10.

The MarMo is a former credit union building renovated by Jimmy McClure. Image via TheCannon.com

"At the end of the day, entrepreneurs are looking for peers that they can do this with and not feel like they are so alone, as well as advisers, mentors, and coaches who help them think differently and investors who can provide some economic capital to help prop up their ideas," Gras explains. "Any programming we do in the future will have elements of social, networking, and education — but all in the confines of making sure we're providing all these different human, economic, and social capital to the entrepreneurs of Galveston."

It's not just toward the Gulf of Mexico where The Cannon has expanded profoundly this year. The company's sportstech hub opened in the Galleria area in collaboration with Braun Enterprises and Gow Media (InnovationMap's parent company).

"The thing that's exciting about this profound growth is it's reflective of the two driving initiatives of the Cannon — one being establishing a network of programmatically connected innovation hubs throughout the entire expanse of the city of Houston," says Lawson Gow, founder of The Cannon. "The other is looking for opportunities where Houston can go deep into an industry and be the best at that."

Sportstech is one of those avenues of opportunity, according to Gow, but the team is always looking for other verticals that might be a similar fit.

Additionally, The Cannon opened a new space in the Esperson building in downtown Houston. This space is small, says Lawson Gow, founder of The Cannon, but has room to grow.

"We want to create network of hubs — some in the community want highly-programed environments," Gow explains, adding that the Esperson Coworking likely won't feature the same level of programming as seen at some of the other locations.

Gow explains that he expects to grow the team at The Cannon to sport these expansions, crediting Gras for building and cultivating the team. Gras joined The Cannon in February.

Alex Gras joined The Cannon as managing director in February, and recently transitioned into chief commercial officer. Photo via LinkedIn

"It wouldn't surprise us if we more than double our team within the next year," Gow says.

This profound growth comes after 18 months of uncertainty — which allowed Gow and his team to rethink some of their plans.

"Pre-covid had our eyes on expansion outside of the city, and we've dialed it back — it's been a healthy exercise", Gow says, "to reset our focus on the whole sprawl of Houston in setting up eight to 10 locations across the city so that we're truly democratizing access to all the tools entrepreneurs need to grow."

What's the future of real estate — and how have technology and the pandemic affected its trajectory? A panel of experts discuss. Photo via Getty Images

Overheard: Houston experts weigh in on the future of tech in real estate

eavesdropping online

The residential and commercial real estate industries have both evolved drastically as new technologies have emerged and in light of the pandemic. But where does that leave renters, homeowners, Realtors, brokers, and everyone else?

A panel of experts looked into their crystal balls and tried to answer this question at a panel for Houston Tech Rodeo last week. They discussed diversity and inclusion, home buying and rental trends, post-pandemic office design, and more on the virtual panel moderated by Allen Thornton, CEO of Money For Your Mission.

To hit the highlights from the virtual panel, check out some overheard moments below. To stream the full broadcast, click here.

“We’re dealing with a different consumer. When you look at the largest pool of buyers of residential real estate — it’s millennials.”

— Bobby Bryant, CEO of Ask Doss. Bryant says these buyers want information than just pictures, square footage, and the school it's zoned to. They want to know about the neighborhood they will be a part of.

“Folks are realizing how much waste comes from buildings — the buildings we spend 90 percent of our time in.”

Natalie Goodman, CEO of Incentifind. She adds that renters and homebuyers, as well as commercial tenants, are increasingly demanding more sustainable options. And the government will pay you to implement these things, Goodman says.

“Before the pandemic, there were already over 60 million freelancers across the country. If the pandemic has taught us anything, it’s that a whole lot more people than just that 60 million are capable of doing a really fantastic job of powering the economy from home."

Reda Hicks, CEO of GotSpot. People are going to be using space differently, so it's about finding those needs and providing the right access to them.

“As human beings, we’ll be drawn to operating and cooperating with other people in environments that are conducive to collaborating and creativity. We’ll probably see innovation ecosystems transition their operational pieces to an online platform. … But we’ll just naturally want to engage with other humans again."

Alexander Gras, managing director of The Cannon. Gras adds that the opportunity for in-person collisions is too important to us as humans.

“People are getting educated and educating themselves, and there’s more inclusion. That means more opportunities for individuals of color to invest in or own residential or commercial real estate.”

— Mark Erogbogbo, influencer at 40 Acre Plan. These emerging opportunities, he adds, need to continue.

“When you don’t need to go to a specific office every day and you can work anywhere, well then you can live anywhere.”

— Sebastien Long, CEO of Lodgeur. The pandemic changed how people regarded their housing. Many opted for more spacious rentals with backyards in less crowded areas. Americans don't have a much time off as Europeans, he adds, so they are rethinking how they work remotely.

“Residential real estate has to be the only industry that sells a product that it doesn’t service.”

— Bryant says, explaining how homebuying is one of the most expensive purchases in people's lives that they use for 8 years on average, yet it's a one-time transaction that also spans across many platforms. "The future of real estate brings everything together in one place."

“What CRE needs to think about if they are going to attract and retain tenants … then they need to think about resilience and build for more extreme weather. And that’s where incentives are going to spike.”

— Goodman adds, referencing the winter storm and the hurricanes Houston gets every season.

“For a very long time, (commercial real estate) has been an industry based on a 10-year lease. There are few people who are willing to take on that kind of relationship because that’s a decade, and nobody knows what’s going to happen tomorrow.”

— Hicks says about the challenge CRE owners face with finding new tenants.

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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.