The Incubator/Accelerator of the Year finalists support startups ranging from hard-tech companies to digital health startups. Photo courtesy of TMC.

Houston is home to numerous accelerators and incubators that support founders in pushing their innovative startups and technologies forward.

As part of our 2025 Houston Innovation Awards, the new Incubator/Accelerator of the Year category honors a local incubator or accelerator that is championing and fueling the growth of Houston startups.

Five incubators and accelerators have been named finalists for the 2025 award. They support startups ranging from hard-tech companies to digital health startups.

Read more about these organizations below. Then join us at the Houston Innovation Awards on Nov. 13 at Greentown Labs, when the winner will be unveiled.

Get your tickets now on sale for this exclusive event celebrating Houston Innovation.

Activate

Hard tech incubator Activate supports scientists in "the outset of their entrepreneurial journey." The Houston hub was introduced last year, and joins others in Boston, New York, and Berkley, California—where Activate is headquartered. It named its second Houston cohort this summer.

This year, the incubator grew to include its largest number of concurrent supported fellows, with 88 companies currently being supported nationally. In total, Activate has supported 296 fellows who have created 236 companies. Those companies have raised over $4 billion in follow-on funding, according to Activate. In Houston, it has supported several Innovation Awards finalists, including Solidec, Bairitone Health and Deep Anchor Solutions. It is led locally by Houston Managing Director Jeremy Pitts.

EnergyTech Nexus

Cleantech startup hub EnergyTech Nexus' mission is to accelerate the energy transition by connecting founders, investors and industrial stakeholders and helping to develop transformative companies, known as "thunderlizards."

The hub was founded in 2023 by CEO Jason Ethier, Juliana Garaizar and Nada Ahmed. It has supported startups including Capwell Services, Resollant, Syzygy Plasmonics, Hertha Metals, EarthEn Energy and Solidec—many of which are current or past Innovation Awards finalists. This year Energy Tech Nexus launched its COPILOT Accelerator, powered by Wells Fargo Innovation Incubator (IN²) at the National Renewable Energy Laboratory (NREL). COPILOT partners with Browning the Green Space, a nonprofit that promotes diversity, equity and inclusion (DEI) in the clean energy and climatech sectors. Energy Tech Nexus also launched its Liftoff fundraising program, its Investor Program, and a "strategic ecosystem partnership" with Greentown Labs.

Greentown Labs

Climatetech incubator Greentown Labs offers its community resources and a network to climate and energy innovation startups looking to grow. The collaborative community offers members state-of-the-art prototyping labs, business resources and access to investors and corporate partners. The co-located incubator was first launched in Boston in 2011 before opening in Houston in 2021.

Greentown has seen major changes and activity this year. In February, Greentown announced Georgina Campbell Flatter as its new CEO, along with a new Board of Directors. In July, it announced Lawson Gow as its Head of Houston, a "dedicated role to champion the success of Greentown Houston’s startups and lead Greentown’s next chapter of impact in the region," according to Greentown. It has since announced numerous new partnerships, including those with Energy Tech Nexus, Los Angeles-based software development firm Nominal, to launch the new Industrial Center of Excellence; and Houston-based Shoreless, to launch an AI lab onsite. Greentown Houston has supported 175 startups since its launch in 2021, with 45 joining in the last two years. Those startups include the likes of Hertha Metals, RepAir Carbon, Solidec, Eclipse Energy (formerly GoldH2) and many others.

Healthtech Accelerator (TMCi)

The Healthtech Accelerator, formerly TMCx, focuses on clinical partnerships to improve healthcare delivery and outcomes. Emerging digital health and medical device startups that join the accelerator are connected with a network of TMC hospitals and seasoned advisors that will prepare them for clinical validation, funding and deployment.

The Healthtech Accelerator is part of Texas Medical Center Innovation, which also offers the TMCi Accelerator for Cancer Therapeutics. The Healthtech Accelerator named its 19th, and latest, cohort of 11 companies last month.

Impact Hub Houston

Impact Hub Houston supports early-stage ventures at various stages of development through innovative programs that address pressing societal issues. The nonprofit organization supports social impact startups through mentorship, connections and training opportunities.

There are more than 110 Impact Hubs globally with 24,000-plus members spanning 69 countries, making it one of the world’s largest communities for accelerating entrepreneurial solutions toward the United Nations' Sustainable Development Goals (SDGs).

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Oxy, Fathom Fund, and Activate have new offices inside the Ion. Photo courtesy of the Ion

Energy, investment groups take up leases in Houston innovation hub

moving in

The Ion in Midtown has some new tenants taking up residence in its 90 percent-leased building.

Occidental Petroleum Corporation, Fathom Fund, and Activate are the latest additions to the Ion, according to a news release from Rice University and the Rice Real Estate Company, which own and operate the 16-acre Ion District where the Ion is located. With the additions, the building has just 10 percent left up for grabs.

“As the Ion continues to attract leading companies and organizations across industries, it’s clear that our vision of creating a dynamic and collaborative environment for innovation is resonating,” Ken Jett, president of the Rice Real Estate Company and vice president of facilities and capital planning at Rice, says in the release. “We are proud to set the standard for how the workplace can evolve to foster the commercialization and growth of transformative technologies that enhance quality of life in our community and beyond.”

Oxy, which was named a corporate partner of the Ion last year, now has nearly 6,500 square feet on the fourth floor. The build out process is slated to be completed by early 2025.

While Oxy represents the corporate side of innovation, the other two additions have their own roles in the innovation arena. Houston-based Fathom Fund, which launched its $100 million fund earlier this year, is targeting deep-tech venture opportunities and is led by Managing Partners Paul Sheng and Eric Bielke.

Founded in Berkeley, California, Activate, which announced its expansion into Houston in 2023, has officially named its local office in the Ion. The hardtech-focused incubator program recently named its inaugural cohort and opened applications for the 2025 program.

Other recent joiners to the Ion includes Kongsberg Digital, Artemis Energy Partners, CES Renewables, and Eleox.

“The partnerships we’ve forged are vital to shaping the Ion into a vibrant ecosystem for startups, where collaborative innovation is not only driving local economic growth but also positioning Houston as a global leader in the energy transition,” Paul Cherukuri, chief innovation officer at Rice University, says. “With our team leading the programming and activation across the Ion district, we are creating companies that harness cutting-edge technology for the benefit of society—advancing solutions that contribute to social good while addressing the most pressing challenges of our time. This powerful network is redefining Houston’s role in the future of energy, technology, and social impact.”

Introducing: Houston Energy and Climate Startup Week, a collaborative initiative that will showcase Houston's ecosystem of energy tech innovators. Photo via Getty Images

Houston organizations team up to bring inaugural climate startup week

mark your calendars

Three organizations are teaming up to put on a week of programming and events focused on energy and climate startups.

Greentown Labs, Halliburton Labs, and the Rice Alliance for Technology and Entrepreneurship have announced Houston Energy and Climate Startup Week 2024 taking place September 9 to 13.

“These organizations will execute events that will serve as a launching pad for an Energy and Climate Startup Week in Houston, showcasing the city as a national hub for the energy future,” Brad Burke, executive director of the Rice Alliance, says in the release. “We welcome the community to bring other energy and climate events to the week, which we’ll cross-promote as the dates approach.”

The week will assemble investors, industry leaders, and startups from across the energy industry and from around the world to showcase Houston's growing sustainable, low-carbon energy future.

The initiative is in collaboration with the Houston Energy Transition Initiative, or HETI, an initiative of the Greater Houston Partnership, as well as Activate, Digital Wildcatters, Renewable Energy Alliance Houston, and TEX-E.

“As the energy capital and one of the most diverse cities in the world, Houston stands as a center point for these solutions. The region is welcoming, diverse and has the know-how to play a critical role in building an energy abundant, low-carbon future," Jane Stricker, executive director of HETI and senior vice president at GHP, says in the release. "We welcome all who want to be part of the solution to join for this exciting, inaugural week of events.”

Attendees can expect tech and startup showcases, panels, pitches, discussions, and networking events to be hosted across Houston and at the Ion, Rice's innovation hub in Midtown. More details on the events will be added to the Ion's website as they become available.

“We look forward to the opportunity to highlight talented founders and connect them with investors, industry practitioners and university resources to help accelerate energy innovation,” Dale Winger, managing director of Halliburton Labs, says in the release. “The collaboration to launch Energy and Climate Startup Week reflects how Houston works together to scale solutions."

Activate's soft opening runs until November 15, with a grand opening planned for November 16-17. Photo courtesy of Activate

New immersive, live-action gaming venue powers up Houston debut

hi, tech

Houston is leveling up its gaming scene with the debut of a new high-tech immersive experience. Called Activate, the indoor venue combines technology and physical activity in 75-minute gaming sessions, which can be played in teams up to five people.

Simply put, the whole place is like stepping inside a live-action arcade.

Activate's first Houston-area location opened softly November 2 at 20225 Katy Frwy., Katy. Official grand opening is set for November 16-17. It is the high-tech brand's sixth location across the country, and second in Texas (behind one in Plano, which opened in spring 2023).

According to a release, the Katy facility spans 9,600 square feet, with 11 different activity rooms offering more than 500 unique games across all difficulty levels. Games include Megagrid, Hoops, Press, Hide, Laser, Strike, Portals, Control, Grid, and more. Radio Frequency Identification (RFID) wristbands track participants’ scores and progress.

"Our mission is to fuse technology, movement, and strategy to create a unique interactive gaming experience," says Activate partner Bryce Anderson in the release. "We want guests to bring their closest friends, family, or co-workers and leave with a feeling of achievement, ready to come back for more."

While gaming activities are mostly adult-focused, children aged 13 and younger can participate with adult supervision.

During Activate's soft opening phase through November 15, 10 percent of sales will be donated to Best Buddies International, a nonprofit that provides mentorships for individuals with intellectual and developmental disabilities. (Check the website for limited hours during soft opening.)

After the grand opening November 16-17, Activate will be open daily, 10 am-10 pm. Gaming sessions (75 minutes) are $24.99 Monday-Thursday, and $29.99 Friday-Sunday. Reservations are encouraged.

Activate has been creating live-action gaming experiences for adults since 2019, and has plans for further expansion, they say.

"As we continue expanding Activate across the United States, we are confident our concept will fill a void for interactive entertainment," says Anderson in the release. "We believe the Houston community will embrace this experience and find it both thrilling and challenging."

More information and reservations can be found on the website.

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This article originally ran on CultureMap.

Activate announced Cyrus Wadia as its new CEO and opened its 2024 applications. Photo courtesy of Activate

New-to-Houston hardtech accelerator names new CEO, opens applications

apply now

A national organization that helps accelerate scientists into entrepreneurs has named its new CEO in the same week that applications opened for its 2024 cohort.

This week, Activate announced Cyrus Wadia as CEO of the organization. Based California, Activate recently expanded to Houston. The two-year accelerator provides funding and support for its selected cohorts.

Wadia most recently served as director of worldwide product sustainability at Amazon. He also oversaw sustainable business and innovation at Nike and was appointed assistant director of clean energy and materials R&D at the White House Office of Science and Technology Policy under President Barack Obama.

"I’m thrilled to join this incredible team at such an exciting moment for the organization. Because of Activate, scientists are designing new products, accelerating the creation of new businesses, and becoming leaders who will transform our future," Wadia says in the news release. "I look forward to building on this momentum to expand the role science leadership plays in solving society’s most pressing issues.”

Wadia’s new role takes effect on October 16. Todd Johnson has served as interim CEO for the past year, and he will return to his role on Activate’s board of directors with the transition. The program's led locally by Jeremy Pitts, managing director for Activate Houston, who was named to the role last month.

The announcement came just a few days before Activate opened applications for its 2024 program — which will be the first year to have a Houston cohort. Applications are open until October 17 across Activate's five programs. The two-year, hardtech-focused program was founded in Berkeley, California, in 2015 and expanded to Boston and New York before launching its virtual program, Activate Anywhere.

“Activate’s recruitment process is crucial, as it centers around finding scientists directly interested in solving urgent problems,” Pitts says. “Activate fellows are turning their technical breakthroughs into businesses that can help industries like manufacturing, energy, chemicals, computing, and agriculture, to meet their decarbonization and resiliency goals.”

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A version of this article originally ran on EnergyCapitalHTX.

Jeremy Pitts has been named the inaugural Houston managing director for Activate. Photo via LinkedIn

Exclusive: New-to-Houston hardtech accelerator names local leader

innovator to know

An organization that promotes early-stage innovation within the hardtech space has named one of the founding entrepreneurs of Greentown Labs as its local Houston lead.

Activate named Jeremy Pitts as the Houston managing director this month. The nonprofit, which announced its new Houston program earlier this year, was founded in Berkeley, California, in 2015 to bridge the gap between the federal and public sectors to deploy capital and resources into the innovators creating transformative products.

For Activate Houston, the challenge is to focus on finding and supporting innovators within the energy sector.

"There are so many reasons to be excited about the energy transition and overall innovation ecosystem in Houston — the region's leadership in energy and desire to maintain that leadership through the energy transition, the many corporations leading the charge to be part of that change who are speaking with their actions and not just their words, the incredible access to talent, the region's diversity, the list goes on and on," Pitts tells InnovationMap.

"Houston is second to none when it comes to solving hard problems and is a region that knows how to build things and execute on projects at the scale needed to tackle the energy transition," he continues.

Pitts was one of the founders of Greentown Labs, and served in a leadership role for the organization between 2011 and 2015. He moved to Houston from Ohio to take the position, but has previously worked in the Bayou City's energy sector.

"Jeremy is the ideal inaugural managing director for Houston — having built a startup there, co-founding the Greentown Labs community, and demonstrating a strong track record of thoughtful mentorship," Aimee Rose, executive managing director of Activate, tells InnovationMap. "Jeremy will serve as the primary guide for our Houston fellows, helping them navigate the ups and downs facing first-time technical founders, and create and foster community among them. He will also plug Activate into the ecosystem to serve as a synergistic partner to all the other amazing initiatives across Texas."

The program finds local and regional early-stage founders — who have raised less than $2 million in funding — who are working on high-impact technology. Each cohort consists of 10 fellows that join the program for two years. The fellows receive a living stipend, connections from Activate's robust network of mentors, and access to a curriculum specific to the program.

Applications for the inaugural Houston cohort for 2024 will open September 15 and will close sometime in October.

Since its inception, Activate has supported 104 companies and around 146 entrepreneurs associated with those companies. With the addition of Houston, Activate will be able to back 50 individuals a year.

"As an impact-focused organization that focuses on turning talented scientists and technology leaders into product and business leaders, Activate enters the Houston ecosystem with no ulterior motives other than finding the right partners and being part of a community that enables scientists to solve hard problems and help make the world a better place," Pitts says. "I have a deep appreciation for all that Houston can offer having started and run a startup here previously and having experience in both traditional energy and climate tech."

Tomorrow, the organization is hosting a virtual event to introduce Pitts and the program to the Houston innovation ecosystem. Those interested in learning more can attend the event or find more information online.

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Houston wearable biosensing company closes $13M pre-IPO round

fresh funding

Wellysis, a Seoul, South Korea-headquartered wearable biosensing company with its U.S. subsidiary based in Houston, has closed a $13.5 million pre-IPO funding round and plans to expand its Texas operations.

The round was led by Korea Investment Partners, Kyobo Life Insurance, Kyobo Securities, Kolon Investment and a co-general partner fund backed by SBI Investment and Samsung Securities, according to a news release.

Wellysis reports that the latest round brings its total capital raised to about $30 million. The company is working toward a Korea Securities Dealers Automated Quotations listing in Q4 2026 or Q1 2027.

Wellysis is known for its continuous ECG/EKG monitor with AI reporting. Its lightweight and waterproof S-Patch cardiac monitor is designed for extended testing periods of up to 14 days on a single battery charge.

The company says that the funding will go toward commercializing the next generation of the S-Patch, known as the S-Patch MX, which will be able to capture more than 30 biometric signals, including ECG, temperature and body composition.

Wellysis also reports that it will use the funding to expand its Houston-based operations, specifically in its commercial, clinical and customer success teams.

Additionally, the company plans to accelerate the product development of two other biometric products:

  • CardioAI, an AI-powered diagnostic software platform designed to support clinical interpretation, workflow efficiency and scalable cardiac analysis
  • BioArmour, a non-medical biometric monitoring solution for the sports, public safety and defense sectors

“This pre-IPO round validates both our technology and our readiness to scale globally,” Young Juhn, CEO of Wellysis, said in the release. “With FDA-cleared solutions, expanding U.S. operations, and a strong AI roadmap, Wellysis is positioned to redefine how cardiac data is captured, interpreted, and acted upon across healthcare systems worldwide.”

Wellysis was founded in 2019 as a spinoff of Samsung. Its S-Patch runs off of a Samsung Smart Health Processor. The company's U.S. subsidiary, Wellysis USA Inc., was established in Houston in 2023 and was a resident of JLABS@TMC.

Elon Musk vows to launch solar-powered data centers in space

To Outer Space

Elon Musk vowed this week to upend another industry just as he did with cars and rockets — and once again he's taking on long odds.

The world's richest man said he wants to put as many as a million satellites into orbit to form vast, solar-powered data centers in space — a move to allow expanded use of artificial intelligence and chatbots without triggering blackouts and sending utility bills soaring.

To finance that effort, Musk combined SpaceX with his AI business on Monday, February 2, and plans a big initial public offering of the combined company.

“Space-based AI is obviously the only way to scale,” Musk wrote on SpaceX’s website, adding about his solar ambitions, “It’s always sunny in space!”

But scientists and industry experts say even Musk — who outsmarted Detroit to turn Tesla into the world’s most valuable automaker — faces formidable technical, financial and environmental obstacles.

Feeling the heat

Capturing the sun’s energy from space to run chatbots and other AI tools would ease pressure on power grids and cut demand for sprawling computing warehouses that are consuming farms and forests and vast amounts of water to cool.

But space presents its own set of problems.

Data centers generate enormous heat. Space seems to offer a solution because it is cold. But it is also a vacuum, trapping heat inside objects in the same way that a Thermos keeps coffee hot using double walls with no air between them.

“An uncooled computer chip in space would overheat and melt much faster than one on Earth,” said Josep Jornet, a computer and electrical engineering professor at Northeastern University.

One fix is to build giant radiator panels that glow in infrared light to push the heat “out into the dark void,” says Jornet, noting that the technology has worked on a small scale, including on the International Space Station. But for Musk's data centers, he says, it would require an array of “massive, fragile structures that have never been built before.”

Floating debris

Then there is space junk.

A single malfunctioning satellite breaking down or losing orbit could trigger a cascade of collisions, potentially disrupting emergency communications, weather forecasting and other services.

Musk noted in a recent regulatory filing that he has had only one “low-velocity debris generating event" in seven years running Starlink, his satellite communications network. Starlink has operated about 10,000 satellites — but that's a fraction of the million or so he now plans to put in space.

“We could reach a tipping point where the chance of collision is going to be too great," said University at Buffalo's John Crassidis, a former NASA engineer. “And these objects are going fast -- 17,500 miles per hour. There could be very violent collisions."

No repair crews

Even without collisions, satellites fail, chips degrade, parts break.

Special GPU graphics chips used by AI companies, for instance, can become damaged and need to be replaced.

“On Earth, what you would do is send someone down to the data center," said Baiju Bhatt, CEO of Aetherflux, a space-based solar energy company. "You replace the server, you replace the GPU, you’d do some surgery on that thing and you’d slide it back in.”

But no such repair crew exists in orbit, and those GPUs in space could get damaged due to their exposure to high-energy particles from the sun.

Bhatt says one workaround is to overprovision the satellite with extra chips to replace the ones that fail. But that’s an expensive proposition given they are likely to cost tens of thousands of dollars each, and current Starlink satellites only have a lifespan of about five years.

Competition — and leverage

Musk is not alone trying to solve these problems.

A company in Redmond, Washington, called Starcloud, launched a satellite in November carrying a single Nvidia-made AI computer chip to test out how it would fare in space. Google is exploring orbital data centers in a venture it calls Project Suncatcher. And Jeff Bezos’ Blue Origin announced plans in January for a constellation of more than 5,000 satellites to start launching late next year, though its focus has been more on communications than AI.

Still, Musk has an edge: He's got rockets.

Starcloud had to use one of his Falcon rockets to put its chip in space last year. Aetherflux plans to send a set of chips it calls a Galactic Brain to space on a SpaceX rocket later this year. And Google may also need to turn to Musk to get its first two planned prototype satellites off the ground by early next year.

Pierre Lionnet, a research director at the trade association Eurospace, says Musk routinely charges rivals far more than he charges himself —- as much as $20,000 per kilo of payload versus $2,000 internally.

He said Musk’s announcements this week signal that he plans to use that advantage to win this new space race.

“When he says we are going to put these data centers in space, it’s a way of telling the others we will keep these low launch costs for myself,” said Lionnet. “It’s a kind of powerplay.”

Johnson Space Center and UT partner to expand research, workforce development

onward and upward

NASA’s Johnson Space Center in Houston has forged a partnership with the University of Texas System to expand collaboration on research, workforce development and education that supports space exploration and national security.

“It’s an exciting time for the UT System and NASA to come together in new ways because Texas is at the epicenter of America’s space future. It’s an area where America is dominant, and we are committed as a university system to maintaining and growing that dominance,” Dr. John Zerwas, chancellor of the UT System, said in a news release.

Vanessa Wyche, director of Johnson Space Center, added that the partnership with the UT System “will enable us to meet our nation’s exploration goals and advance the future of space exploration.”

The news release noted that UT Health Houston and the UT Medical Branch in Galveston already collaborate with NASA. The UT Medical Branch’s aerospace medicine residency program and UT Health Houston’s space medicine program train NASA astronauts.

“We’re living through a unique moment where aerospace innovation, national security, economic transformation, and scientific discovery are converging like never before in Texas," Zerwas said. “UT institutions are uniquely positioned to partner with NASA in building a stronger and safer Texas.”

Zerwas became chancellor of the UT System in 2025. He joined the system in 2019 as executive vice chancellor for health affairs. Zerwas represented northwestern Ford Bend County in the Texas House from 2007 to 2019.

In 1996, he co-founded a Houston-area medical practice that became part of US Anesthesia Partners in 2012. He remained active in the practice until joining the UT System. Zerwas was chief medical officer of the Memorial Hermann Hospital System from 2003 to 2008 and was its chief physician integration officer until 2009.

Zerwas, a 1973 graduate of the Houston area’s Bellaire High School, is an alumnus of the University of Houston and Baylor College of Medicine.