Q&A

Houston native brings LatinX startup support to the Ion with HQ move

Jesse Martinez, founder of the LatinX Startup Alliance, joins InnovationMap for a Q&A on why he's relocating his nonprofit to Houston. Photo courtesy of LSA

Jesse Martinez was working in Silicon Valley before it was Silicon Valley. He took his years of experience within that tech ecosystem and launched the LatinX Startup Alliance to support his fellow Hispanic entrepreneurs — and now he's bringing that support to his hometown.

The LatinX Startup Alliance will move its headquarters into The Ion in 2022, Martinez tells InnovationMap. He's excited to finally make his professional return to Houston and to help support the diverse ecosystem — one that has been created with diversity at the forefront, unlike Silicon Valley and other coastal tech hubs.

"We're on the ground floor. We're helping to build that foundation. It's not an afterthought. It's not something that now we're trying to go back and think of diversity," Martinez tells InnovationMap. "I think that's the beautiful thing about Houston and everyone that I've met is that it's been so diverse and inclusive. That spirit is already there. So, how do we just maximize that?"

Martinez joined InnovationMap for a Q&A about the new HQ announcement and what he's excited about in terms of DEI in Houston's tech scene.

InnovationMap: Tell me a little bit about your own tech and entrepreneurship journey.

Jesse Martinez: In 1996, one weekend I was at Barnes and Noble reading the newspaper, and, for whatever reason, I went through the classified ads and this one ad caught my eye. It said, "internet sales for internet company." So I faxed in my resume and I got a call back, did my phone screens, and they flew me out to San Jose. I interviewed with the founders in Sunnyville where the startup was based. The name of the startup was Internet Systems Inc., funded by Sequoia Capital and I ended up joining as employee number 27.

I was new to this whole world. We were one of two pioneers in the web hosting services space — pre-Rackspace, pre-AWS, et cetera. In less than a year, we went from startup to public company trading at $35 a share via two acquisitions. So that was my whole intro into the world of tech startups, Silicon Valley, and stock options.

Because of that work, I caught the startup bug and did my first startup with my brother in 2000. We had two acquisition offers. We turned one down, and we were entertaining the second one, which was between $8 and $10 million. And then the market crashed in March of 2000. Those offers went away, and we tried to raise more money, but just couldn't do it. And then we ended up shutting down December of 2000.

IM: How did you come to start the LatinX Alliance?

JM: In 2010, I was looking to do my second startup. And it was early days of community-based organizations providing services for their founders — Black founders, Jewish founders, and others. And I did a set of Google searches to try to find something for myself. I'm like, "I'm Latino, I'm a tech and founder what's available for us?" And there was nothing. That left me scratching my head. Like how can this be? This is the global mecca of tech. That became the beginning of Latino Startup Alliance. We launched in 2011 in the Mission District of San Francisco with six people with their mission to empower Latino tech founders. Fast forward to today, we're over a thousand members globally. Our mission is still the same. And last year, we changed our name from Latino to LatinX to be more supportive and inclusive.

IM: You’re from Houston originally, but when did you have the idea of bringing the alliance to Texas?

JM: I was super excited to meet Bob Harvey (from the Greater Houston Partnership) and team, when they did a delegation to Silicon Valley. I met them at the Salesforce Tower, and we started talking about tech and Aggies and all the above. And they're like, "by the way, do you know that we're know committing to tech? We're finally making that commitment from the city on down, you should be there." And I'm like, "well, I've been waiting for this all my life." Houston was so engaged in oil, gas and energy. And so it was finally refreshing to hear that Houston had made that commitment. It felt right and it made sense to move our headquarters to Houston, and we'll officially launch in 2022.

IM: The new headquarters of the LatinX Startup Alliance is in The Ion. How will you work with them collaboratively and what can people expect from your organization?

JM: One of the things that we did early on as an organization is do a series of events — weekly events as well as a yearly summits. We were actually going to host our first summit in October of this year, because of the pandemic and the uncertainty, we decided to postpone it just because we wanted to be respectful for everyone's health and safety. We pushed it to next year, targeting the same month — October of 2022. And that'll be two days of programming focused on tech and also tech careers. So, there'll be a Friday and a Saturday. One of the things we want to ensure is that by hosting something on Saturday on tech careers, is that more people will be able to attend. And then Friday we'll focus on tech, founders, and startups.

Through our monthly events, we'll have office hours, we'll have meetups, and what we call LSA founder dinners. We just hosted one last week in Oakland, and we used to do these all the time. We're going back to that now that we can, and especially as we launch in Houston is ensuring that we have that consistency as we start building that community. It's like starting over, which is great. The biggest part is being able to support and champion the LatinX tech community here in Houston and also the state of Texas.

IM: How do you envision growing the LatinX Startup Alliance internationally? 

JM: We've always been global from day one. We've had founders come from other cities and countries to Silicon Valley because it was such a hub for many, many years. It'll be interesting to see what happens moving forward. A lot of people have moved away to their hometowns or new cities. So now we have a more distributed network of founders and startups and also investors. So when you talk about access and access to opportunities, it's certainly a big win for those founders and startups across the west.

IM: What should people know about LSA? 

JM: We operate under three pillars, which are awareness, access, and acceleration. Through the awareness piece, it's creating awareness around LatinX tech, startups and founders, both of those that are in the ecosystem and those that want to learn more. Access is being able to include people in tech programming, again for founders or for the public to participate in whatever it is we post, you know, from a founder perspective, it could be an invitation to attend Techcrunch or SaaStr Annual— either virtually or in person in San Francisco. We've had a partnership with both of them. So, we have diversity scholarships for our members.

IM: How have you seen things change in terms of connecting LatinX founders with funding?

JM: There is more access, and we help facilitate some of the awareness. You might not be aware of all the investors angel investors. And so that's where we try to be the bridge and be able to make those warm introductions between investors and also the startup founders. There are a lot more diverse funds. There's a lot more diverse general partners, which is awesome. And I think there's access to more. Does that mean that everyone's getting funded? No. It's not easier to get money, but there's just more money to go around. But you still have to go through the same steps and follow the process.

IM: Ahead of the launch of the LatinX Startup Alliance in Houston, who are you looking to connect with?

JM: Everyone, because you never know who that one person's going to be —corporates, companies, startups, founders, investors, other nonprofits. One of things that I've been doing as I've been going back to Houston is just meeting people from the ecosystem.One of the things that we're working on right now is setting up a group of key stakeholders for LatinX Houston Alliance. Who are those key players that we can bring together on a monthly basis? I'm thinking like a town hall of 40 or so people talk about what we need to do to better support and champion the ecosystem.

------

This conversation has been edited for brevity and clarity.

Trending News

Building Houston

 
 

A Rice research team is tapping into materials science to better understand Alzheimer’s disease, a UH professor is developing a treatment for hereditary vision loss, and a BCM researcher is looking at stress and brain cancer. Photo by Gustavo Raskosky/Rice University

Research, perhaps now more than ever, is crucial to expanding and growing innovation in Houston — and it's happening across the city right under our noses.

In InnovationMap's latest roundup of research news, three Houston institutions are working on life-saving health care research thanks to new technologies.

Rice University scientists' groundbreaking alzheimer's study

Angel Martí (right) and his co-authors (from left) Utana Umezaki and Zhi Mei Sonia He have published their latest findings on Alzheimer’s disease. Photo by Gustavo Raskosky/Rice University

According to the Centers for Disease Control and Prevention, Alzheimer’s disease will affect nearly 14 million people in the U.S. by 2060. A group of scientists from Rice University are looking into a peptide associated with the disease, and their study was published in Chemical Science.

Angel Martí — a professor of chemistry, bioengineering, and materials science and nanoengineering and faculty director of the Rice Emerging Scholars Program — and his team have developed a new approach using time-resolved spectroscopy and computational chemistry, according to a news release from Rice. The scientists "found experimental evidence of an alternative binding site on amyloid-beta aggregates, opening the door to the development of new therapies for Alzheimer’s and other diseases associated with amyloid deposits."

Amyloid plaque deposits in the brain are a main feature of Alzheimer’s, per Rice.

“Amyloid-beta is a peptide that aggregates in the brains of people that suffer from Alzheimer’s disease, forming these supramolecular nanoscale fibers, or fibrils” says Martí in the release. “Once they grow sufficiently, these fibrils precipitate and form what we call amyloid plaques.

“Understanding how molecules in general bind to amyloid-beta is particularly important not only for developing drugs that will bind with better affinity to its aggregates, but also for figuring out who the other players are that contribute to cerebral tissue toxicity,” he adds.

The National Science Foundation and the family of the late Professor Donald DuPré, a Houston-born Rice alumnus and former professor of chemistry at the University of Louisville, supported the research, which is explained more thoroughly on Rice's website.

University of Houston professor granted $1.6M for gene therapy treatment for rare eye disease

Muna Naash, a professor at UH, is hoping her research can result in treatment for a rare genetic disease that causes vision loss. Photo via UH.edu

A University of Houston researcher is working on a way to restore sight to those suffering from a rare genetic eye disease.

Muna Naash, the John S. Dunn Endowed Professor of biomedical engineering at UH, is expanding a method of gene therapy to potentially treat vision loss in patients with Usher Syndrome Type 2A, or USH2A, a rare genetic disease.

Naash has received a $1.6 million grant from the National Eye Institute to support her work. Mutations of the USH2A gene can include hearing loss from birth and progressive loss of vision, according to a news release from UH. Naash's work is looking at applying gene therapy — the introduction of a normal gene into cells to correct genetic disorders — to treat this genetic disease. There is not currently another treatment for USH2A.

“Our goal is to advance our current intravitreal gene therapy platform consisting of DNA nanoparticles/hyaluronic acid nanospheres to deliver large genes in order to develop safe and effective therapies for visual loss in Usher Syndrome Type 2A,” says Naash. “Developing an effective treatment for USH2A has been challenging due to its large coding sequence (15.8 kb) that has precluded its delivery using standard approaches and the presence of multiple isoforms with functions that are not fully understood."

BCM researcher on the impact of stress

This Baylor researcher is looking at the relationship between stress and brain cancer thanks to a new grant. Photo via Andriy Onufriyenko/Getty Images

Stress can impact the human body in a number of ways — from high blood pressure to hair loss — but one Houston scientist is looking into what happens to bodies in the long term, from age-related neurodegeneration to cancer.

Dr. Steven Boeynaems is assistant professor of molecular and human genetics at Baylor College of Medicine. His lab is located at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and he also is a part of the Therapeutic Innovation Center, the Center for Alzheimer’s and Neurodegenerative Diseases, and the Dan L Duncan Comprehensive Cancer Center at Baylor.

Recently, the Cancer Prevention and Research Institute of Texas, or CPRIT, awarded Boeynaems a grant to continue his work studying how cells and organisms respond to stress.

“Any cell, in nature or in our bodies, during its existence, will have to deal with some conditions that deviate from its ideal environment,” Boeynaems says in a BCM press release. “The key issue that all cells face in such conditions is that they can no longer properly fold their proteins, and that leads to the abnormal clumping of proteins into aggregates. We have seen such aggregates occur in many species and under a variety of stress-related conditions, whether it is in a plant dealing with drought or in a human patient with aging-related Alzheimer’s disease."

Now, thanks to the CPRIT funding, he says his lab will now also venture into studying the role of cellular stress in brain cancer.

“A tumor is a very stressful environment for cells, and cancer cells need to continuously adapt to this stress to survive and/or metastasize,” he says in the release.

“Moreover, the same principles of toxic protein aggregation and protection through protein droplets seem to be at play here as well,” he continues. “We have studied protein droplets not only in humans but also in stress-tolerant organisms such as plants and bacteria for years now. We propose to build and leverage on that knowledge to come up with innovative new treatments for cancer patients.”

Trending News