We're no. 1

Houston-area suburb claims top spot for business-savvy cities list from Verizon

The city of Sugar Land has been named a business-savvy city. Photo by Matthew T. Carroll/Getty Images

Sugar Land has landed some sweet recognition for its business-friendly atmosphere.

A new ranking from Go.Verizon.com puts Sugar Land first among what it calls "the most business-savvy cities in America." The study looked only at cities with at least 100,000 residents.

"Landing the coveted top position on our list, business owners in this suburb outside of Houston know a thing or two about doing it bigger," Go.Verizon.com says. "With a mean household income of $157,923 and an unemployment rate of only 3 percent, Sugar Land lives up to its statue of the strong-willed Stephen Austin, the 'Father of Texas.'"

Six factors went into the ranking:

  1. Average household income.
  2. Unemployment rate.
  3. Percentage of people with at least a bachelor's degree.
  4. Number of applications to start a business.
  5. Percentage of population that starts a business.
  6. Homeownership rate.

"Doing business in Sugar Land might be the best decision you make. As a welcoming and inclusive city, Sugar Land provides a business-friendly environment," says Keri Schmidt, president and CEO of the Fort Bend Chamber of Commerce. "The Fort Bend Chamber works collaboratively with the city to support to our businesses in both good times and challenging times."

Key sectors of the economy in Sugar Land, home to roughly 118,500 residents, include manufacturing, biotech, financial services, and energy. Among the major employers are Accredo Packaging, Champion X, Fluor, and Schlumberger.

Sugar Land-based Accredo, which makes packaging mostly for food and consumer products, set up shop in Sugar Land in 2009. Following a 200,000-square-foot, $50 million expansion last year at the Sugar Land Business Park, the company now occupies nearly 550,000 square feet at its 32-acre warehouse and manufacturing site. When the expansion was completed last year, Accredo said it would be adding 100 jobs through 2021.

"Accredo has continued to grow and expand as a thriving global company," Sunny Sharma, president of the Sugar Land Legacy Foundation, said in 2019. "Their products cross international borders, and we are fortunate that they choose Sugar Land to connect the world."

One other Texas city appears on the Go.Verizon.com list: eighth-ranked Frisco, a suburb of Dallas-Fort Worth.

"Frisco residents can spend confidently: The mean household income is $153,704," Go.Verizon.com says. "Business owners in the city provide plenty of places for citizens to spend all that cash — Frisco has video game museums, vintage automobile collections, and outdoor concert venues."

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Building Houston

 
 

This UH engineer is hoping to make his mark on cancer detection. Photo via UH.edu

Early stage cancer is hard to detect, mostly because traditional diagnostic imaging cannot detect tumors smaller than a certain size. One Houston innovator is looking to change that.

Wei-Chuan Shih, professor of electrical and computer engineering at the University of Houston's Cullen College of Engineering, recently published his findings in IEEE Sensors journal. According to a news release from UH, the cells around cancer tumors are small — ~30-150nm in diameter — and complex, and the precise detection of these exosome-carried biomarkers with molecular specificity has been elusive, until now.

"This work demonstrates, for the first time, that the strong synergy of arrayed radiative coupling and substrate undercut can enable high-performance biosensing in the visible light spectrum where high-quality, low-cost silicon detectors are readily available for point-of-care application," says Shih in the release. "The result is a remarkable sensitivity improvement, with a refractive index sensitivity increase from 207 nm/RIU to 578 nm/RIU."

Wei-Chuan Shih is a professor of electrical and computer engineering at the University of Houston's Cullen College of Engineering. Photo via UH.edu

What Shih has done is essentially restored the electric field around nanodisks, providing accessibility to an otherwise buried enhanced electric field. Nanodisks are antibody-functionalized artificial nanostructures which help capture exosomes with molecular specificity.

"We report radiatively coupled arrayed gold nanodisks on invisible substrate (AGNIS) as a label-free (no need for fluorescent labels), cost-effective, and high-performance platform for molecularly specific exosome biosensing. The AGNIS substrate has been fabricated by wafer-scale nanosphere lithography without the need for costly lithography," says Shih in the release.

This process speeds up screening of the surface proteins of exosomes for diagnostics and biomarker discovery. Current exosome profiling — which relies primarily on DNA sequencing technology, fluorescent techniques such as flow cytometry, or enzyme-linked immunosorbent assay (ELISA) — is labor-intensive and costly. Shih's goal is to amplify the signal by developing the label-free technique, lowering the cost and making diagnosis easier and equitable.

"By decorating the gold nanodisks surface with different antibodies (e.g., CD9, CD63, and CD81), label-free exosome profiling has shown increased expression of all three surface proteins in cancer-derived exosomes," said Shih. "The sensitivity for detecting exosomes is within 112-600 (exosomes/μL), which would be sufficient in many clinical applications."

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