The city of Sugar Land has been named a business-savvy city. Photo by Matthew T. Carroll/Getty Images

Sugar Land has landed some sweet recognition for its business-friendly atmosphere.

A new ranking from Go.Verizon.com puts Sugar Land first among what it calls "the most business-savvy cities in America." The study looked only at cities with at least 100,000 residents.

"Landing the coveted top position on our list, business owners in this suburb outside of Houston know a thing or two about doing it bigger," Go.Verizon.com says. "With a mean household income of $157,923 and an unemployment rate of only 3 percent, Sugar Land lives up to its statue of the strong-willed Stephen Austin, the 'Father of Texas.'"

Six factors went into the ranking:

  1. Average household income.
  2. Unemployment rate.
  3. Percentage of people with at least a bachelor's degree.
  4. Number of applications to start a business.
  5. Percentage of population that starts a business.
  6. Homeownership rate.

"Doing business in Sugar Land might be the best decision you make. As a welcoming and inclusive city, Sugar Land provides a business-friendly environment," says Keri Schmidt, president and CEO of the Fort Bend Chamber of Commerce. "The Fort Bend Chamber works collaboratively with the city to support to our businesses in both good times and challenging times."

Key sectors of the economy in Sugar Land, home to roughly 118,500 residents, include manufacturing, biotech, financial services, and energy. Among the major employers are Accredo Packaging, Champion X, Fluor, and Schlumberger.

Sugar Land-based Accredo, which makes packaging mostly for food and consumer products, set up shop in Sugar Land in 2009. Following a 200,000-square-foot, $50 million expansion last year at the Sugar Land Business Park, the company now occupies nearly 550,000 square feet at its 32-acre warehouse and manufacturing site. When the expansion was completed last year, Accredo said it would be adding 100 jobs through 2021.

"Accredo has continued to grow and expand as a thriving global company," Sunny Sharma, president of the Sugar Land Legacy Foundation, said in 2019. "Their products cross international borders, and we are fortunate that they choose Sugar Land to connect the world."

One other Texas city appears on the Go.Verizon.com list: eighth-ranked Frisco, a suburb of Dallas-Fort Worth.

"Frisco residents can spend confidently: The mean household income is $153,704," Go.Verizon.com says. "Business owners in the city provide plenty of places for citizens to spend all that cash — Frisco has video game museums, vintage automobile collections, and outdoor concert venues."

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Houston space company lands latest NASA deal to advance lunar logistics

To The Moon

Houston-based space exploration, infrastructure, and services company Intuitive Machines has secured about $2.5 million from NASA to study challenges related to carrying cargo on the company’s lunar lander and hauling cargo on the moon. The lander will be used for NASA’s Artemis missions to the moon and eventually to Mars.

“Intuitive Machines has been methodically working on executing lunar delivery, data transmission, and infrastructure service missions, making us uniquely positioned to provide strategies and concepts that may shape lunar logistics and mobility solutions for the Artemis generation,” Intuitive Machines CEO Steve Altemus says in a news release.

“We look forward to bringing our proven expertise together to deliver innovative solutions that establish capabilities on the [moon] and place deeper exploration within reach.”

Intuitive Machines will soon launch its lunar lander on a SpaceX Falcon 9 rocket to deliver NASA technology and science projects, along with commercial payloads, to the moon’s Mons Mouton plateau. Lift-off will happen at NASA’s Kennedy Space Center in Florida within a launch window that starts in late February. It’ll be the lander’s second trip to the moon.

In September, Intuitive Machines landed a deal with NASA that could be worth more than $4.8 billion.

Under the contract, Intuitive Machines will supply communication and navigation services for missions in the “near space” region, which extends from the earth’s surface to beyond the moon.

The five-year deal includes an option to add five years to the contract. The initial round of NASA funding runs through September 2029.

Play it back: Houston home tech startup begins 2025 with fresh funding

HOUSTON INNOVATORS PODCAST EPISODE 272

One of the dozen or so Houston startups kicking of the new year with fresh funding is SmartAC.com, a company that's designed a platform that enables contractors in the HVAC and plumbing industries to monitor, manage, and optimize their maintenance memberships through advanced sensors, AI-driven diagnostics, and proactive alerts.

Last month, the SmartAC.com raised a follow-on round with support from local investor Mercury to continue growth and expansion of the product, which has evolved on many ways since the company launched in 2020, emerging from stealth with $10 million raised in a series A. In a May 2023 interview for the Houston Innovators Podcast, Founder and CEO Josh Teekell explained how he embraced the power of a pivot.

The company's sensors can monitor all aspects of air conditioning units and report back any issues, meaning homeowners have quicker and less costly repairs. While SmartAC.com started with providing the service and tech to homeowners directly, Teekell says he's had a greater interest in working with plumbers and HVAC companies who then deploy the technology to their customers.

"It became quite evident that homeowners don't care about air conditioning really at all until their system breaks," Teekell says on the show. "The technology is really built around giving those contractors as another way to gain a customer relationship and keep it."

Revisit the podcast episode below where Teekell talks about SmartAC.com's last raise.

SmartAC.com's previous round in 2023 — a $22 million series B — was used grow its team that goes out to deploy the technology and train the contractors on the platform.

"We've been very fortunate to get some of the biggest names in Houston on our cap table," Teekell says in the May 2023 conversation. "Since we're raising a bunch of money locally, everyone understands what a pain air conditioning can be."

Houston biotech company tests hard-to-fight cancer therapeutics

fighting cancer

A Houston-based, female-founded biotech company has developed a treatment that could prove to be an effective therapy for a rare blood cancer.

Cellenkos Therapeutics has completed promising Phase 1b testing of its Treg cell therapy, CK0804, in the fight against myelofibrosis. According to a news release from the Cellenkos team, the use of its cord-blood-derived therapeutics could signal a paradigm shift for the treatment of this hard-to-fight cancer.

Cellenkos was founded by MD Anderson Cancer Center physician and professor Simrit Parmar. Her research at the hospital displayed the ability of a unique subset of T cells’ capability to home in on a patient’s bone marrow, restoring immune balance, and potentially halting disease progression.

Myelofibrosis has long been treated primarily with JAK (Janus Kinase) inhibitors, medications that help to block inflammatory enzymes. They work by suppressing the immune response to the blood cancer, but don’t slow the progression of the malady. And they’re not effective for every patient.

“There is a significant need for new therapeutic options for patients living with myelofibrosis who have suboptimal responses to approved JAK inhibitors,” Parmar says. “We are greatly encouraged by the safety profile and early signs of efficacy observed in this patient cohort and look forward to continuing our evaluation of the clinical potential of CK0804 in our planned expansion cohort.”

The expansion cohort is currently enrolling patients with myelofibrosis. What exactly are sufferers dealing with? Myelofibrosis is a chronic disease that causes bone marrow to form scar tissue. This makes it difficult for the body to produce normal blood cells, leaving patients with fatigue, spleen enlargement and night sweats.

Myelofibrosis is rare, with just 16,000 to 18,500 people affected in the United States. But for patients who don’t respond well to JAKs, the prognosis could mean a shorter span than the six-year median survival rate outlined for the disease by Cleveland Clinic.

Helping myelofibrosis patients to thrive isn’t the only goal for Cellenkos right now.

The company seeks to aid people with rare conditions, particularly inflammatory and autoimmune disorders, with the use of CK0804, but also other candidates including one known as CK0801. The latter drug has shown promising efficacy in aplastic anemia, including transfusion independence in treated patients.

The company closed its $15 million series A round led by BVCF Management, based in Shanghai, in 2021. Read more here.