Plug and Play is opening a Sugar Land hub to accelerate startups and innovation across smart cities, energy, health, and mobility sectors. Photo courtesy of Plug and Play

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.

League City, Sugar Land, and Pearland were just crowned among the top 10 safest and most affordable cities to live in the U.S. Photo via Getty Images

3 affordable Houston neighbors rank among America's 10 safest cities

HIGH PRAISE FOR THE 'BURBS

Crime may be a concern for some Houstonians, but life is a little more relaxed just beyond the city limits.

Three Houston-area suburbs – League City, Sugar Land, and Pearland – were just crowned among the top 10 safest and most affordable cities to live in the U.S., as declared in a new report by GoBankingRates.

The study, "50 Safest and Most Affordable US Cities To Live In," ranked the largest U.S. cities by population based on their cost of living and crime rate averages. Crime rates were determined based on the number of crimes per 1,000 city residents from the FBI’s Crime Data Explorer in 2022, the year with the most recent available data.

League City proudly landed in the No. 4 spot nationally, thanks to its low property and violent crime rates as well as a high median household income. Sugar Land and Pearland weren't too far behind in the top 10, ranking No. 6 and No. 7, respectively. The report emphasized these suburbs all offer "vibrant cultural scenes" and strong job markets for adults, along with great schools and abundant recreational activities for families to enjoy.

A League City household makes a median income of $117,316 annually, with an average mortgage cost of $2,216 per month, the report found. The total monthly cost of living in the family friendly city adds up to $4,157.

There were a total of 1,497 property crimes reported in the city in 2022, and 126 total violent crimes. For context, the U.S. Census Bureau estimated the population in League City spans more than 116,000 residents in 2023. That means the city's rate for violent crimes is 1.08 per 1,000 residents, and the property crime rate is 12.85 per 1,000 residents, according to the findings.

Sugar Land's median household income is much higher than League City's, at $132,247 per year. However, so were the average mortgage costs ($2,715 per month) and total monthly cost of living ($4,852).

There were 1,745 property crimes and 97 violent crimes reported in Sugar Land in 2022. That would place Sugar Land's property crime rate at 16.16 per 1,000 city residents, and 0.90 violent crimes per 1,000 residents.

Here's how the report breaks down Pearland's cost of living and crime rate statistics:

  • Median household income: $111,123
  • Household average mortgage cost: $2,257
  • Total monthly cost of living: $4,352
  • Property crimes (reported in 2022): 2,152
  • Property crime per 1,000 residents: 17.09
  • Violent crimes (reported in 2022): 117
  • Violent crime per 1,000 residents: .93

Large Texas cities, such as Houston proper, Dallas, Fort Worth, Austin, and San Antonio, were all noticeably absent in the ranking. This is likely because – as most Texans are aware – bigger cities often have higher crime rates and higher costs of living than their outlying suburbs.

"Choosing a family-friendly place to live is a significant decision that involves a balancing act between safety and affordability in any big city," the report said. "Whether you’re a young professional, a growing family or a retiree, finding real estate where you feel comfortable — both physically and financially — is crucial for a high quality of life."

Other Texas cities that were ranked in the top 25 safest and most affordable places to live include El Paso (No. 11), McKinney (No. 15), Frisco (No. 16), Laredo (No. 18), Grand Prairie (No. 21), Plano (No. 22), Carrollton (No. 23), and McAllen (No. 24).

The top 10 safest and most affordable U.S. cities to live in are:

  • No. 1 – Elgin, Illinois
  • No. 2 – Cary, North Carolina
  • No. 3 – Gilbert, Arizona
  • No. 4 – League City, Texas
  • No. 5 – Rochester, Minnesota
  • No. 6 – Sugar Land, Texas
  • No. 7 – Pearland, Texas
  • No. 8 – Meridian, Idaho
  • No. 9 – Broken Arrow, Oklahoma
  • No. 10 – Olathe, Kansas
The full report and its methodology can be found on gobankingrates.com

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The Woodlands ranked No. 24 out of 343 U.S. cities. Photo via thewoodlands.com

Houston suburb clocks in among best job markets in America

by the numbers

In a surprising turn of events, it's not Houston proper that's earning recognition for its job market, but The Woodlands. The north Houston suburb boasts the No. 24 best job market in the nation, according to a new report by SmartAsset.

The study examined 343 U.S. cities across six main data points from 2021 and 2022, for which the most recent data is available: A city's unemployment rates; median income to housing payment ratio, commute times, the percentage of remote workers, the percentage of employed residents with health insurance, and income growth between 2019-2022.

The report discovered that The Woodlands has a 4.8 percent unemployment rate, and its residents' median earnings landed at $73,079 annually. The average housing costs in The Woodlands make up 28.7 percent of an individual's yearly income, which can be estimated at about $1,750 per month.

Remote-work flexibility was another major consideration in the study. Working from home means no real commute time, as long as you don't count the time it takes to get out of bed and walk into the home office. Unfortunately for The Woodlands, a majority of workers are commuting to their jobs, and only 24.5 percent of employees work remotely.

For those who do need to drive to-and-from work, a separate SmartAsset study on remote workforces discovered the average commute time in The Woodlands is about 27 minutes long.

Houston fell far behind in the report, landing at No. 272 out of 343 total U.S. cities. The city's unemployment rate is only 5.9 percent, but its residents' median earnings barely tip over $38,000 a year. Only 11.5 percent of Houstonians work from home, and their housing costs account for 39.4 percent of their total income.

Houston ranked outside the top 20 best cities for tech workers earlier in 2024, further highlighting a significant downward shift in the employment atmosphere for the region.

"With costs of living skyrocketing in recent years and the demand for different skill sets changing, job seekers must be resourceful to find opportunities that best suit them," the report said. "This could mean relocating for higher income, an improved work-life balance, growth potential or benefits."

Other Houston-area cities that made it in the top 200 in the report are:

  • No. 99 – Sugar Land
  • No. 113 – Pearland
  • No. 172 – League City
The full report and its methodology can be found on smartasset.com.

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This article originally ran on CultureMap.

The study's findings are shedding light on further growing financial stress and affordability struggles throughout the U.S., likely heightened by inflation and cost of living increases. Photo via Getty Images

Here's what it takes to be a middle class earner in Houston in 2024

by the numbers

No one wants to hear that they aren't making enough money to be considered "middle class," but those income ceilings are getting more difficult to maintain year after year across the Houston area. And a new report has revealed The Woodlands has the No. 10 highest income ceiling for American middle class earners in 2024.

According to the 2024 edition of SmartAsset's annual "What It Takes to Be Middle Class in America" report, middle class households in The Woodlands would need to make between $91,548 and $274,670 a year to be labeled "middle class." Additionally, the suburb's median middle class household income comes out to $137,335 a year.

The report used a variation of Pew Research's definition of a middle class household, stating the salary range is "two-thirds to double the median U.S. salary." To determine income limits, the report analyzed data from the Census Bureau's 2022 one-year American Community Survey. New to the 2024 report, SmartAsset widened its analysis of income data from 100 to 345 of the largest American cities.

The Woodlands' middle class income thresholds are egregiously higher than the national average, the study found.

"In a large U.S. city, a middle-class income averages between $52,000 and $155,000," the report says. "The median household income across all 345 cities is $77,345, making middle-class income limits fall between $51,558 and $154,590."

Sugar Land was right behind The Woodlands, ranking No. 13 out of all 345 U.S. cities, with households needing to make between $88,502 and $265,532 a year to maintain their "middle class" status.

In a shocking turn of events, Houston plummeted into No. 254 this year after ranking among the top 100 in SmartAsset's 2023 report. At the time, a Houston household needed to make between $37,184 and $110,998 a year to be considered middle class. But the latest findings from the 2024 report show the necessary salary range to maintain a middle class designation in Houston is now between $40,280 and $120,852 a year.

The study's findings are shedding light on further growing financial stress and affordability struggles throughout the U.S., likely heightened by inflation and cost of living increases.

"As a middle-class American, there is some expectation for living a lifestyle of relative comfort," the report said. "But as costs have increased significantly over the last few years, the middle class is now feeling a squeeze in their finances."

Here’s what it takes to be middle class in other Houston-area cities:

  • No. 34 – Atascocita: between $71,748 and $215,266 a year
  • No. 39 – League City: between $69,904 and $209,734 a year
  • No. 45 – Pearland: between $69,990 and $206,992 a year
  • No. 211 – Conroe: between $43,814 and $131,456 a year
  • No. 273 – Pasadena: between $38,048 and $114,156 a year

Middle class income thresholds within the top 10 U.S. cities
The Woodlands wasn't the only Texas city to earn a spot in the top 10. Frisco, a suburb outside of Dallas, ranked two spots higher to claim No. 8 in the national comparison of U.S. cities with the highest income thresholds to be labeled middle class.

Middle class households in Frisco need to make between $97,266 and $291,828 a year, with the median household income at $145,914, according to the report.

Unsurprisingly, half of the top 10 cities with the highest middle class income ceilings are in California. The report found households in four of the five cities could be bringing in over $300,000 a year in income and still be classified as middle class.

California’s overall high cost-of-living means residents in the No. 1 city of Sunnyvale would need to make between $113,176 and $339,562 a year to be labeled middle class. Sunnyvale overtook Fremont for the top spot in the report in 2024.

The top 10 cities with the highest middle class ceilings are:

  • No. 1 – Sunnyvale, California
  • No. 2 – Fremont, California
  • No. 3 – San Mateo, California
  • No. 4 – Santa Clara, California
  • No. 5 – Bellevue, Washington
  • No. 6 – Highlands Ranch, Colorado
  • No. 7 – Carlsbad, California
  • No. 8 – Frisco, Texas
  • No. 9 – Naperville, Illinois
  • No. 10 – The Woodlands, Texas

The full report and its methodology can be found on smartasset.com.

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The Sugar Land Office of Economic Development and Tourism arranged financial incentives and financing options for the new headquarters. Photo via sugarlandecodev.com

Houston company moves to suburb for $4M new HQ

headed southwest

Frazer, a manufacturer of emergency vehicles, is shifting its headquarters from Houston to Sugar Land — a move that will bring 286 jobs to the Fort Bend County suburb.

The company plans to invest $4 million in its new headquarters, a two-story, 23-year-old facility that it’s leasing from CVH Capital Partners. The previous tenant was Thermo Fisher Scientific. The building, at 1410 Gillingham Ln., encompasses 150,000 square feet.

Frazer’s current headquarters is at 7219 Rampart St., near the intersection of Bissonnet Street and Renwick Drive.

“Being just minutes outside of Houston, Sugar Land has always been on our radar,” Laura Griffin, CEO of Frazer, says in a news release. “It’s home to a growing business environment, a robust workforce, and reliable infrastructure. It’s an ideal destination for us to grow and serve our customers.”

The Sugar Land Office of Economic Development and Tourism arranged financial incentives and financing options for the new headquarters.

“We are committed to boosting our business community and empowering our workforce by fostering business relationships,” says Elizabeth Huff, executive director of the economic development office. “Frazer’s expansion is proof of our success in this endeavor.”

Frazer, founded in 1956, makes and sells mobile clinics, mobile stroke units, and ambulances for fire departments and emergency services providers. Houston-area customers include Texas Children’s Hospital, UTHealth Houston, the Bellaire Fire Department, the Harris County Hospital District, the Houston Fire Department, and the Montgomery County Hospital District.

The Woodlands is the U.S. city with the No. 10 biggest holiday spending budget in 2023, and a few other Texas neighborhoods rank highly as well. The Woodlands Mall/Facebook

Houston suburb ranks No. 10 for holiday spending

shop 'til you drop

Santa and his elves get busier with every passing year, but sometimes even Kris Kringle has to use his black card to get the job done. And according to a new study by Wallethub, Santa's gonna be working overtime to fulfill the orders for residents of The Woodlands this holiday season.

The personal finance experts have determined The Woodlands is the U.S. city with the No. 10 biggest holiday spending budget in 2023. Shoppers in the affluent Houston suburb are expected to spend $3,316 this festive season.

According to the U.S. Census Bureau, The Woodlands' estimated population of 114,436 had a median household income of $130,011.

This is The Woodlands' first time in the holiday shopping spotlight. The Houston suburb ranked a much lower – No. 71 – in last year's report with an average spending budget of $1,733. Way to step it up.

The nearby city of Sugar Land is a returnee, and moved up one place from No. 15 last year into No. 14 this year. The average holiday budget for a Sugar Land household is $3,210.

Houston fell into No. 209 this year with an average household holiday budget of $1,296. Houston skyrocketed away from its previous rank as No. 366 in 2022 with an average spending budget of $890.

Six other East Texas cities landed in this year's report on the heftiest holiday budgets:

  • No. 31 – Pearland ($2,566)
  • No. 34 – Missouri City ($2,517)
  • No. 234 – Beaumont ($1,244)
  • No. 238 – Pasadena ($1,237)
  • No. 407 – Conroe ($935)
  • No. 438 – Baytown ($872)

Each year, WalletHub calculates the maximum holiday budget for over 550 U.S. cities "to help consumers avoid post-holiday regret," the website says. The study factors in income, age of the population, and other financial indicators such as debt-to-income ratio, monthly-income-to monthly-expenses ratio, and savings-to-monthly-expenses ratio.

Shoppers will have to keep a closer eye on their bank accounts this year while they search for the best gifts for their loved ones. Many consumers are running out of savings accumulated during the height of the COVID-19 pandemic, according to Yao Jin, an associate professor of supply chain management at Miami University.

To combat overspending, Jin suggests setting hard budgets based on personal financial circumstances and develop a list of "must haves" rather than "nice to haves."

"Holiday times are festive, and retailers know that festivities can boost mood and lead to a propensity to overspend," he said in the Wallethub report. "In fact, that is also why retailers tend to have more generous return policies to both alleviate concerns of unwanted gifts and buyer’s remorse. The key to avoiding holiday overspending is for consumers to take the emotions out of the decision, to the extent possible."

Other Texas cities that made it in the top 100 include:
  • No. 3 – Frisco ($3,546)
  • No. 5 – Flower Mound ($3,485)
  • No. 22 – Allen ($2,964)
  • No. 30 – Plano ($2,566)
  • No. 44 – Cedar Park ($2,354)
  • No. 56 – McKinney ($2,165)
  • No. 67 – Carrollton ($1,928)
  • No. 71 – Austin ($1,877)
  • No. 77 – Richardson ($1,809)
  • No. 95 – League City ($1,733)
  • No. 99 – North Richland Hills ($1,706)

The report and its methodology can be found on wallethub.com.

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This article originally ran on CultureMap.

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Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”

Autonomous truck company with Houston routes goes public

on a roll

Kodiak Robotics, a provider of AI-powered autonomous vehicle technology, has gone public through a SPAC merger and has rebranded as Kodiak AI. The company operates trucking routes to and from Houston, which has served as a launchpad for the business.

Privately held Kodiak, founded in 2018, merged with a special purpose acquisition company — publicly held Ares Acquisition Corp. II — to form Kodiak AI, whose stock now trades on the Nasdaq market.

In September, Mountain View, California-based Kodiak and New York City-based Ares disclosed a $145 million PIPE (private investment in public equity) investment from institutional investors to support the business combo. Since announcing the SPAC deal, more than $220 million has been raised for the new Kodiak.

“We believe these additional investments underscore our investors’ confidence in the value proposition of Kodiak’s safe and commercially deployed autonomous technology,” Don Burnette, founder and CEO of Kodiak, said in a news release.

“We look forward to leading the advancement of the commercial trucking and public sector industries,” he added, “and delivering on the exciting value creation opportunities ahead to the benefit of customers and shareholders.”

Last December, Kodiak debuted a facility near George Bush Intercontinental/Houston Airport for loading and loading driverless trucks. Transportation and logistics company Ryder operates the “truckport” for Ryder.

The facility serves freight routes to and from Houston, Dallas and Oklahoma City. Kodiak’s trucks currently operate with or without drivers. Kodiak’s inaugural route launched in 2024 between Houston and Dallas.

One of the companies using Kodiak’s technology is Austin-based Atlas Energy Solutions, which owns and operates four driverless trucks equipped with Kodiak’s driver-as-a-service technology. The trucks pick up fracking sand from Atlas’ Dune Express, a 42-mile conveyor system that carries sand from Atlas’ mine to sites near customers’ oil wells in the Permian Basin.

Altogether, Atlas has ordered 100 trucks that will run on Kodiak’s autonomous technology in an effort to automate Atlas’ supply chain.

Rice University scientists invent new algorithm to fight Alzheimer's

A Seismic Breakthrough

A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

To prove this link, researchers at Rice, alongside Boston University, developed a computational algorithm called “Single-cell Expression Integration System for Mapping Genetically Implicated Cell Types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

“As we age, some brain cells naturally slow down, but in dementia — a memory-loss disease — specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

“We built our SEISMIC algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

“We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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This article originally appeared on CultureMap.com.