Cougar cash

University of Houston roars with massive $1.2 billion raised in new campaign

The Coogs have scored some serious cash. Photo courtesy of University of Houston

The University of Houston Cougars have a reason to roar this fall. The school has announced a massive fundraising feat of $1.2 billion for scholarships, professorships, facilities, and programs as part of the "Here, We Go" initiative that closed on August 31.

Specifically, the campaign raised $1,235,427,334. The final tally was announced by UH System Chancellor and UH president Renu Khator during her 12th annual fall address on October 28., where she thanked high-profile donors and volunteer campaign co-chairs Tilman J. Fertitta ('78), Beth Madison ('72), John L. Nau III, and Marvin E. Odum III (M.B.A. '95).

The campaign, which surpassed the $1 billion milestone in 2019, some 18 months ahead of schedule, was designed to strategically transform UH System universities with priorities to support student scholarships and fellowships, build state-of-the-art facilities, attract and retain top faculty, advance academic programs, workforce training and research, and build a nationally relevant athletics program, according to a press release. It began in 2012 and launched publicly in January 2017, before concluding in August of this year.

More than 187,000 donors, including 133,000 new donors contributed to the campaign, highlighting the pride felt by alumni and friends. Donations came from all 50 states and 46 countries, according to the school.

Donation highlights include:

  • $50 million gift from an anonymous donor — the campaign's single largest contribution to hire faculty and establish four new institutes in the areas of energy, infrastructure, precision medicine, and global engagement.
  • $20 million from Tilman J. Fertitta for renovation and construction of the Fertitta Center, a 7,100-seat multi-purpose arena that is home to the Houston Cougars men's and women's basketball teams and the women's volleyball team.
  • $20 million from the John P. McGovern Foundation benefitting arts students and faculty. The Kathrine G. McGovern College of the Arts was named in honor of the gift.
  • $17 million from Andy and Andrea Diamond to create the Diamond Family Scholars program which offers financial, academic and mentoring support for students aging out of the foster care system.
  • $16 million from the John M. O'Quinn Foundation to support the UH Law Center and construction of its new state-of-the-art building, the John M. O'Quinn Law Building.
  • $15 million thanks to Humana Inc. to launch the Humana Integrated Health System Sciences Institute and help defray start-up and operational costs for the UH College of Medicine, as well as fund endowed chairs at several UH colleges.
  • $13 million from the Cyvia and Melvyn Wolff Family Foundation to the nation's No. 1 undergraduate entrepreneurship program at the C.T. Bauer College of Business with a total expected impact of $15 million with matching gift.

"You inspired us to dream big, challenged us to be relevant and forced us to stay focused," said Khator, in a statement. "You led us from all directions, often making calls for us and introducing us to people who cared about Houston and our role in Houston's future."

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This article originally ran on CultureMap.

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Building Houston

 
 

A Rice research team is tapping into materials science to better understand Alzheimer’s disease, a UH professor is developing a treatment for hereditary vision loss, and a BCM researcher is looking at stress and brain cancer. Photo by Gustavo Raskosky/Rice University

Research, perhaps now more than ever, is crucial to expanding and growing innovation in Houston — and it's happening across the city right under our noses.

In InnovationMap's latest roundup of research news, three Houston institutions are working on life-saving health care research thanks to new technologies.

Rice University scientists' groundbreaking alzheimer's study

Angel Martí (right) and his co-authors (from left) Utana Umezaki and Zhi Mei Sonia He have published their latest findings on Alzheimer’s disease. Photo by Gustavo Raskosky/Rice University

According to the Centers for Disease Control and Prevention, Alzheimer’s disease will affect nearly 14 million people in the U.S. by 2060. A group of scientists from Rice University are looking into a peptide associated with the disease, and their study was published in Chemical Science.

Angel Martí — a professor of chemistry, bioengineering, and materials science and nanoengineering and faculty director of the Rice Emerging Scholars Program — and his team have developed a new approach using time-resolved spectroscopy and computational chemistry, according to a news release from Rice. The scientists "found experimental evidence of an alternative binding site on amyloid-beta aggregates, opening the door to the development of new therapies for Alzheimer’s and other diseases associated with amyloid deposits."

Amyloid plaque deposits in the brain are a main feature of Alzheimer’s, per Rice.

“Amyloid-beta is a peptide that aggregates in the brains of people that suffer from Alzheimer’s disease, forming these supramolecular nanoscale fibers, or fibrils” says Martí in the release. “Once they grow sufficiently, these fibrils precipitate and form what we call amyloid plaques.

“Understanding how molecules in general bind to amyloid-beta is particularly important not only for developing drugs that will bind with better affinity to its aggregates, but also for figuring out who the other players are that contribute to cerebral tissue toxicity,” he adds.

The National Science Foundation and the family of the late Professor Donald DuPré, a Houston-born Rice alumnus and former professor of chemistry at the University of Louisville, supported the research, which is explained more thoroughly on Rice's website.

University of Houston professor granted $1.6M for gene therapy treatment for rare eye disease

Muna Naash, a professor at UH, is hoping her research can result in treatment for a rare genetic disease that causes vision loss. Photo via UH.edu

A University of Houston researcher is working on a way to restore sight to those suffering from a rare genetic eye disease.

Muna Naash, the John S. Dunn Endowed Professor of biomedical engineering at UH, is expanding a method of gene therapy to potentially treat vision loss in patients with Usher Syndrome Type 2A, or USH2A, a rare genetic disease.

Naash has received a $1.6 million grant from the National Eye Institute to support her work. Mutations of the USH2A gene can include hearing loss from birth and progressive loss of vision, according to a news release from UH. Naash's work is looking at applying gene therapy — the introduction of a normal gene into cells to correct genetic disorders — to treat this genetic disease. There is not currently another treatment for USH2A.

“Our goal is to advance our current intravitreal gene therapy platform consisting of DNA nanoparticles/hyaluronic acid nanospheres to deliver large genes in order to develop safe and effective therapies for visual loss in Usher Syndrome Type 2A,” says Naash. “Developing an effective treatment for USH2A has been challenging due to its large coding sequence (15.8 kb) that has precluded its delivery using standard approaches and the presence of multiple isoforms with functions that are not fully understood."

BCM researcher on the impact of stress

This Baylor researcher is looking at the relationship between stress and brain cancer thanks to a new grant. Photo via Andriy Onufriyenko/Getty Images

Stress can impact the human body in a number of ways — from high blood pressure to hair loss — but one Houston scientist is looking into what happens to bodies in the long term, from age-related neurodegeneration to cancer.

Dr. Steven Boeynaems is assistant professor of molecular and human genetics at Baylor College of Medicine. His lab is located at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and he also is a part of the Therapeutic Innovation Center, the Center for Alzheimer’s and Neurodegenerative Diseases, and the Dan L Duncan Comprehensive Cancer Center at Baylor.

Recently, the Cancer Prevention and Research Institute of Texas, or CPRIT, awarded Boeynaems a grant to continue his work studying how cells and organisms respond to stress.

“Any cell, in nature or in our bodies, during its existence, will have to deal with some conditions that deviate from its ideal environment,” Boeynaems says in a BCM press release. “The key issue that all cells face in such conditions is that they can no longer properly fold their proteins, and that leads to the abnormal clumping of proteins into aggregates. We have seen such aggregates occur in many species and under a variety of stress-related conditions, whether it is in a plant dealing with drought or in a human patient with aging-related Alzheimer’s disease."

Now, thanks to the CPRIT funding, he says his lab will now also venture into studying the role of cellular stress in brain cancer.

“A tumor is a very stressful environment for cells, and cancer cells need to continuously adapt to this stress to survive and/or metastasize,” he says in the release.

“Moreover, the same principles of toxic protein aggregation and protection through protein droplets seem to be at play here as well,” he continues. “We have studied protein droplets not only in humans but also in stress-tolerant organisms such as plants and bacteria for years now. We propose to build and leverage on that knowledge to come up with innovative new treatments for cancer patients.”

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