The city tapped key partners for the initiative, including a Houston startup. Photo courtesy

City officials and business leaders in Houston are recruiting employers to collectively offer at least 12,000 paid jobs and internships this summer for local 16- to 24-year-olds.

Organizers on March 8 kicked off this year’s Hire Houston Youth initiative. It encourages employers in the public, private, and philanthropic sectors to bring aboard youth for summertime jobs and internships.

One of the program's partner is Ampersand, a Houston-based startup and tech platform that has designed a career-readiness curriculum for this age group. In partnership with the City of Houston, Ampersand customized a portion of its curriculum to upskill and prepare young Houstonians for the workforce across 35 lessons, five modules, and four hours of content — all of which provide essential job skills ranging from email best practices to mental health management in the workplace.

Employers can sign up for Hire Houston Youth online. The deadline for youth to apply for jobs or internships through this program has been extended from March 11 to April 8.

“Employment plays a pivotal role in reducing gender, ethnic, racial, and other social inequalities,” Mayor Sylvester Turner says in a news release. “Therefore, providing meaningful employment experiences for our youth is in the best interest of all, including young people, their communities, and Houston as a whole.”

In 2021, as the city coped with the height of the COVID-19 pandemic, Hire Houston Youth offered more than 9,500 opportunities. This year, Turner hopes the program can produce at least 12,000 jobs and internships, and as many as 15,000.

The National League of Cities recently awarded a $150,000 grant to Hire Houston Youth. In addition to the grant, Houston will receive assistance from National League of Cities staff and other experts to advance the city’s efforts to expand STEM career opportunities for marginalized young people.

The unemployment rate for 16- to 24-year-olds in the U.S. ranks as the highest among all age groups. In the pre-pandemic year of 2019, the national unemployment rate for the 16 to 24 age group stood at 8.4 percent. No other age group had an unemployment rate above 4.1 percent in 2019.

The jobless rate for people of color and lower-income people in this age group has historically been higher than the overall rate for that age group.

The pandemic exacerbated unemployment woes for 16- to 24-year-olds in the Houston area around the country. Data compiled by the Schultz Family Foundation and Mathematica shows that during the peak of the pandemic, youth unemployment rates in the Houston area ranged between a low of 12.6 percent from July to December 2020 and a high of 16.1 percent from January to June 2021.

The Measure of America project estimates that more than 4.1 million Americans in the 16-24 group are neither working nor attending school. In Harris County, 13.4 percent of 16- to 24-year-olds in Harris County met that definition in 2017, according to the Federal Reserve Bank of Dallas.

“The years 16-24 are crucial for the development of human capital — through activities such as education and workforce preparation that pay dividends in the form of higher wages, lower unemployment, and other benefits later in life. Yet even before the pandemic, many young people were disconnected from school and work and the economic opportunities that follow,” the Federal Reserve Bank of Dallas says in a 2021 report.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”