3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Aziz Gilani of Mercury, Yaxin Wang of the Texas Heart Institute, and Atul Varadhachary of Fannin Innovation. Photos courtesy

Editor's note: Welcome to another Monday edition of Innovators to Know. Today I'm introducing you to three Houstonians to read up about — three individuals behind recent innovation and startup news stories in Houston as reported by InnovationMap. Learn more about them and their recent news below by clicking on each article.


Aziz Gilani, managing director at Mercury

Aziz Gilani, managing director at Mercury, joins the Houston Innovators Podcast. Photo via LinkedIn

Aziz Gilani's career in tech dates back to when he'd ride his bike from Clear Lake High School to a local tech organization that was digitizing manuals from mission control. After years working on every side of the equation of software technology, he's in the driver's seat at a local venture capital firm deploying funding into innovative software businesses.

As managing director at Mercury, the firm he's been at since 2008, Gilani looks for promising startups within the software-as-a-service space — everything from cloud computing and data science and beyond.

"Once a year at Mercury, we sit down with our partners and talk about the next investment cycle and the focuses we have for what makes companies stand out," Gilani says on the Houston Innovators Podcast. "The current software investment cycle is very focused on companies that have truly achieved product-market fit and are showing large customer adoption." Read more.


Yaxin Wang, director of the Texas Heart Institute's Innovative Device & Engineering Applications Lab

The project is funded by a four-year, $7.8 million grant. THI will use about $2.94 million of that to fund its part of the research. Photo via texasheart.org

The United States Department of Defense has awarded a grant that will allow the Texas Heart Institute and Rice University to continue to break ground on a novel left ventricular assist device (LVAD) that could be an alternative to current devices that prevent heart transplantation and are a long-term option in end-stage heart failure.

The grant is part of the DOD’s Congressionally Directed Medical Research Programs (CDMRP). It was awarded to Georgia Institute of Technology, one of four collaborators on the project that will be designed and evaluated by the co-investigator Yaxin Wang. Wang is part of O.H. “Bud” Frazier’s team at Texas Heart Institute, where she is director of Innovative Device & Engineering Applications Lab. The other institution working on the new LVAD is North Carolina State University.

The project is funded by a four-year, $7.8 million grant. THI will use about $2.94 million of that to fund its part of the research. As Wang explained to us last year, an LVAD is a minimally invasive device that mechanically pumps a person’s own heart. Frazier claims to have performed more than 900 LVAD implantations, but the devices are far from perfect. Read more.

Atul Varadhachary, managing director of Fannin Innovation

Atul Varadhachary also serves as CEO and president of Allterum Therapeutics. Photo via LinkedIn

Allterum Therapeutics, a Houston biopharmaceutical company, has been awarded a $12 million product development grant from the Cancer Prevention and Research Institute of Texas (CPRIT).

The funds will support the clinical evaluation of a therapeutic antibody that targets acute lymphoblastic leukemia (ALL), one of the most common childhood cancers.

However, CEO and President Atul Varadhachary, who's also the managing director of Fannin Innovation, tells InnovationMap, “Our mission has grown much beyond ALL.” Read more.

Yaxin Wang is director of THI's Innovative Device & Engineering Applications Lab. Photo via texasheart.org

Houston health tech innovator collaborates on promising medical device funded by DOD

team work

The United States Department of Defense has awarded a grant that will allow the Texas Heart Institute and Rice University to continue to break ground on a novel left ventricular assist device (LVAD) that could be an alternative to current devices that prevent heart transplantation and are a long-term option in end-stage heart failure.

The grant is part of the DOD’s Congressionally Directed Medical Research Programs (CDMRP). It was awarded to Georgia Institute of Technology, one of four collaborators on the project that will be designed and evaluated by the co-investigator Yaxin Wang. Wang is part of O.H. “Bud” Frazier’s team at Texas Heart Institute, where she is director of Innovative Device & Engineering Applications Lab. The other institution working on the new LVAD is North Carolina State University.

The project is funded by a four-year, $7.8 million grant. THI will use about $2.94 million of that to fund its part of the research. As Wang explained to us last year, an LVAD is a minimally invasive device that mechanically pumps a person’s own heart. Frazier claims to have performed more than 900 LVAD implantations, but the devices are far from perfect.

The team working on this new research seeks to minimize near-eventualities like blood clot formation, blood damage, and driveline complications such as infection and limitations in mobility. The four institutions will try to innovate with a device featuring new engineering designs, antithrombotic slippery hydrophilic coatings (SLIC), wireless power transfer systems, and magnetically levitated driving systems.

Wang and her team believe that the non-contact-bearing technology will help to decrease the risk of blood clotting and damage when implanting an LVAD. The IDEA Lab will test the efficacy and safety of the SLIC LVAD developed by the multi-institutional team with a lab-bench-based blood flow loop, but also in preclinical models.

“The Texas Heart Institute continues to be a leading center for innovation in mechanical circulatory support systems,” said Joseph G. Rogers, MD, the president and CEO of THI, in a press release.

“This award will further the development and testing of the SLIC LVAD, a device intended to provide an option for a vulnerable patient population and another tool in the armamentarium of the heart failure teams worldwide.”

If it works as hypothesized, the SLIC LVAD will improve upon current LVAD technology, which will boost quality of life for countless heart patients. But the innovation won’t stop there. Technologies that IDEA Lab is testing include wireless power transfer for medical devices and coatings to reduce blood clotting could find applications in many other technologies that could help patients live longer, healthier lives.

This week's roundup of Houston innovators includes Kelsey Hultberg of Sunnova, Brad Burke of Rice Alliance, and Yaxin Wang of the Texas Heart Institute. Photos courtesy

3 Houston innovators to know this week

who's who

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from health care to energy tech — recently making headlines in Houston innovation.

Kelsey Hultberg, executive vice president of corporate communications and sustainability of Sunnova Energy International

Kelsey Hultberg, executive vice president of corporate communications and sustainability at Sunnova Energy, joins the Houston Innovators Podcast. Photo courtesy of Sunnova

Several years ago, Kelsey Hultberg decided to make a pivot. Looking for a role with career growth opportunities, the communications professional thought she'd find something at an oil and gas company, but then she met John Berger, founder and CEO of Sunnova, who was looking for someone to stand up their communications team amidst the solar energy company's growth.

"He hooked me," Hultberg shares on the Houston Innovators Podcast. "He said, 'I've got big plans for this company. I see where this energy industry is going, I see that we're prime for a transition, and I want to take this company public.' And I started a few weeks later."

Hultberg has been telling the story for Sunnova — which equips customers with solar and storage technology, providing them with energy independence — ever since, through scaling, new technologies, and its IPO in 2019. Read more.

Houston Innovation Awards names longtime Rice leader as 2023 Trailblazer

Brad Burke has been named the 2023 Trailblazer Award recipient. Photo via alliance.rice.edu

In less than a month, all of Houston's innovation community's movers and shakers will gather to celebrate the Houston Innovation Awards, and the night's first honoree has officially been named.

Brad Burke, managing director of the Rice Alliance for Technology and Entrepreneurship, was selected to receive the 2023 Trailblazer Award. The award was established to recognize an individual who has already left a profound impact on Houston's business and innovation ecosystem and is dedicated to continuing to support Houston and its entrepreneurs.

The award, which is selected from a group of internal and external nominations, was decided by a vote of the 2023 awards judges, who represent Houston's business, investment, and entrepreneurial community across industries. Read more.

Yaxin Wang leads the IDEA Lab at the Texas Heart Institute. Photo via texasheart.org

Meet Yaxin Wang, PhD. The research engineer leads the IDEA Lab at the Texas Heart Institute. IDEA stands for Innovative Device & Engineering Applications, an apt description of what Wang and her colleagues do. She’s currently focused intensely on projects that could radically change transplantation for patients in need of an artificial heart or new, healthy lungs.

Specifically, Wang is helping to develop a pediatric left ventricular assist device (NeoVAD) to mechanically pump that part of the heart in infants and small children born with heart defects.

“There aren’t a lot of options for very small kids,” explains Wang. “That’s why we’re working on an implantable LVAD for very young kids.” Read more.

Yaxin Wang leads the IDEA Lab at the Texas Heart Institute. Photo via texasheart.org

Houston innovator backed by NIH grant tackles congenital heart disease in pediatric patients

good idea

In 1969, Dr. Denton A. Cooley implanted the first total artificial heart in a living patient. Most Houstonians know Cooley’s name, but fewer can name his colleague, Dr. Domingo Liotta, who created the device. Liotta died last year at the age of 97, but his work continues at the Texas Heart Institute.

Meet Yaxin Wang, PhD. The research engineer leads the IDEA Lab at THI. IDEA stands for Innovative Device & Engineering Applications, an apt description of what Wang and her colleagues do. She’s currently focused intensely on projects that could radically change transplantation for patients in need of an artificial heart or new, healthy lungs.

Specifically, Wang is helping to develop a pediatric left ventricular assist device (NeoVAD) to mechanically pump that part of the heart in infants and small children born with heart defects.

“There aren’t a lot of options for very small kids,” explains Wang. “That’s why we’re working on an implantable LVAD for very young kids.”

In fact, as many as 14,000 children with congenital heart disease are hospitalized each year waiting for a new heart, but only around 500 pediatric transplants actually take place.

Essentially, once patients reach their teens, their chest cavities are large enough for an adult donor heart. But smaller children means smaller rib cages and fewer available hearts. For children born with heart disease, Wang’s LVAD could be a lifesaver. Because she has crafted minimally invasive devices that were developed for long-term use, patients could live far longer than before.

The project, funded by a $2.8 million NIH grant, has a big name attached. Dr. O.H. Frazier is a THI legend who claims to have performed 900 LVAD implantations, not to mention some 1,200 heart transplants. In April, the team published their initial findings regarding the success of and improvements in making rotary LVADs over the last half-century.

A different team, also led by Frazier and Wang, received a pair of grants this summer. That includes $2.8 million from the NIH and a total of $7.8 million from a DoD focused program and a THI sub-award. Their work will center on a novel centrifugal left-ventricular assist device intended for end-stage heart failure patients, a potentially safer alternative to a heart transplant.

But Wang isn’t solely focused on the heart. Working with Dr. Gabriel Loor, a cardiothoracic surgeon at Baylor College of Medicine, Wang is also responsible for a method of preserving the lungs for a longer stretch of time, which would allow for further transport, and in the more distant future, potential genetic modification before transplantation. Using animal models for the moment, “they can survive for several hours without any issues,” says Wang.

The pioneering researcher is well on her way to making a name for herself at the Texas Heart Institute and beyond. And soon, she’ll be saving countless lives.

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Houston universities climb the ranks on annual list of most patents issued

top 100

The University of Houston and Rice University have claimed spots on the National Academy of Inventor's Top 100 U.S. Universities Granted Utility Patents.

The list is based on data obtained from the U.S. Patent and Trademark Office and ranks U.S. academic institutions that are advancing innovation by the number of utility patents issued in the prior year.

Utility patents are among the world’s most valuable assets because they give inventors exclusive commercial rights to produce and use their technology. The universities ranked on the list collectively hold nearly 6,500 patents.

“In the ever-evolving innovation landscape, it is imperative that the U.S. is remaining competitive and at the forefront of today’s emerging research and technologies,” Paul R. Sanberg, president of the NAI, said in a news release. “Ensuring the security of intellectual property through patenting is a crucial component to this and allows those innovations to be effectively moved to market, where they can create valuable societal and economic impact. The Top 100 U.S. list celebrates U.S. universities and their inventive staff and faculty for their dedication in ensuring their innovations and IP are protected.”

The University of Houston System came in at No. 62 with 34 patents, and Rice University claimed the No. 68 spot with 30 patents.

Both universities climbed up the rankings this year. Last year, UH was ranked No. 63 with 27 patents. Rice climbed an impressive 26 spots this year, after ranking No. 94 with 14 patents issued in 2023.

“Granted U.S. utility patents can tremendously help in commercializing the technologies covered by such patents by attracting industry investment and commercial partners on a global level,” Neha Malik, assistant director for intellectual property management in Rice's Office of Technology Transfer, said in a release. “Advancing in this list memorializes Rice’s commitment to support research programs of Rice faculty by generating a path for the university to bring its research to the marketplace.”

Other Texas universities on the list include:

  • No. 3 University of Texas System (234 patents)
  • No. 35 The Texas A&M System (61 patents)
  • No. 73 Texas Tech University System (25 patents)
  • No. 80 Baylor University (20 patents)

The University of California (540 patents) claimed the No. 1 spot again this year, followed by the Massachusetts Institute of Technology (295 patents), which also placed second for 2024.

First large-scale affordable housing project of 3D-printed homes rises in Houston

Building Blocks

What’s being promoted as the world’s first large-scale affordable housing development built using 3D technology is taking shape in Houston.

Houston-based 3D construction company HiveASMBLD has teamed up with Houston-based Cole Klein Builders and the City of Houston on the Zuri Gardens project. Located near Hobby Airport on Martindale Road, the first 3D-printed home at Zuri Gardens is set to be completed in October.

“Zuri Gardens was born from the frustration of watching hardworking families get priced out of safe, resilient housing. We knew there had to be a better way — and with this project, we’re proving that there is,” says Vanessa Cole, co-founder of Cole Klein Builders.

“By combining visionary design, advanced construction technology, and powerful partnerships, we’re building more than just homes — we’re creating a blueprint for the future of equitable homeownership in Houston and beyond.”

The development is being created for households earning up to 120 percent of the median income in the Houston metro area. For a four-member household in the Houston area, the 120 percent limit in 2025 is $121,300, as set by the U.S. Department of Housing and Urban Development (HUD).

The 13-acre Zuri Gardens development will feature 80 energy-efficient homes averaging 1,360 square feet. Prices will be in the mid to high $200s. The homes will qualify for up to $125,000 in down payment assistance from the City of Houston.

HiveASMBLD will print two different home designs, each with two-bedroom and two-and-a-half bathroom configurations, along with an office/flex space and a covered patio.

Zuri Gardens home model Houston Courtesy rendering

“The community we envision for Zuri Gardens is modern, safe, and one that residents will be proud to call home. When completed using HiveASMBLD’s innovative technology, this 3D-printed multifamily community will exemplify the future of residential affordable living,” says Timothy Lankau, founder and co-CEO of HiveASMBLD.

Developments like Zuri Gardens are popping up around the country.

“3D-printed homes are revolutionizing the construction industry by making home builds faster, cheaper, and more sustainable,” according to The Zebra, an Austin-based insurance marketplace. “In less than 24 hours, 3D printers can print the foundation and walls for a small home at a fraction of the cost of typical construction.”

U.S. News & World Report explains that unlike a traditional home, a 3D-printed home is printed in place, “just like you’d print a knickknack on your home 3D printer. Layer by layer, proprietary concrete blends are used to build the wall systems of the home in any type of design that a builder can imagine.”

Texas is home to several trailblazing 3D-printed projects.

In the U.S., the first 3D-printed home was built in 2018 in Austin, and the first 3D-printed multistory home was completed in 2023 in Harris County’s Spring Branch neighborhood. Meanwhile, the world’s largest neighborhood of 3D-printed homes is located in the Austin suburb of Georgetown.

Grand View Research predicts the global market for 3D-printed construction will approach $4.2 billion by 2030.

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This article originally appeared on CultureMap.com.

Houston tech company secures $450M NASA contract

space deal

NASA’s Johnson Space Center awarded Houston-based aerospace technology and engineering services company Barrios Technology the Mission Technical Integration Contract (MTIC).

The two-year contract is worth $450 million and will begin Oct. 1, 2025.

Barrios will provide technical and management support to some of NASA’s human spaceflight programs, which include the Orion and Gateway programs, the International Space Station (ISS) and possibly more human spaceflight initiatives.

The contract represents a continuation of Barrios’ Human Space Flight Technical Integration Contract (HSFTIC), which has been in effect since 2020.

“We are incredibly proud to have been selected by NASA to continue working side by side with them in shaping the future of human space exploration,” Kelly Page, president of Barrios Technology, said in a news release.

The contract also includes support for program, business, configuration and data management, information technology, systems engineering and integration, mission integration, safety and mission assurance, and operations according to Barrios.

Barrios will be supported by subcontractors ARES Technical Services Corp., Booz Allen Hamilton, Intuitive Machines, Summit Technologies & Solutions, and TechTrans International (TTI).

“This award is a testament to the passion, hard work, and extraordinary value that our Barrios family brings every single day,” Page added in the release. “This is not just another contract award—it is the continuation of a generational commitment to our NASA customers and their critical missions.”

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