10+ can't-miss Houston business and innovation events for February

WHERE TO BE

Don't miss these February events — from talks with the hall-of-fame beauty business founders to AI summits. Photo courtesy of Rice University

From talks with the hall-of-fame beauty business founders to agtech and AI summits, Houston will host a number of events focused on innovation and innovators in February.

Here’s what not to miss and how to register.

Note: This post might be updated to add more events.

Feb. 7 – SheSpace Offsite: Coffee & Connection

Get out of the office and head over to Midtown network with fellow SheSpace members and working women via coffee and conversation.

This event is Friday, Feb. 7, from 2-4 p.m. at Kefita Coffee. RSVP here.

Feb. 11 – Texas Business Hall of Fame x Ion: Creators Series with Founders Janet Gurwitch (Laura Mercier) and Tiffany Masterson (Drunk Elephant)

Take part in Texas Business Hall of Fame’s launch of its Creators 2025 speaker series. Janet Gurwitch, founder of Laura Mercier, and Tiffany Masterson, founder of Drunk Elephant, will discuss lessons learned while building their global retail brands and their successful exits.

This event is Tuesday, Feb. 11, from 8–10 a.m. at the Ion. Register here.

Feb. 11 – How to Start a Startup

Gain insight from Mercury Fund’s Heath Butler and stick around for a happy hour afterward. This session, originally scheduled for Jan. 21, is geared toward entrepreneurs, small business owners, investors and academic partners

This event is Tuesday, Feb. 11, from 5:30–7 p.m. at the Ion. Register here.

Feb. 15 – Ion Family Tech Day: Youth Entrepreneurship with Lemonade Day University

Bring the whole family out to the Ion for a family-friendly entrepreneurial workshop with Lemonade Day. Kids can compete in a pitch competition to win free supplies, and trained instructors will coach kids on how to set goals, develop a business or marketing plan and budget, create a brand, save and invest money, and more.

This event is Saturday, Feb. 15, from 10 a.m.–12:30 p.m. at the Ion. Register here.

Feb. 18 — Female Founders and Friends

Connect with like-minded female founders, funders, and allies at this recurring event. Female Founders & Friends is open to all industries and coffee is provided.

This event is Tuesday, Feb. 18, at 9 a.m. at Sesh Coworking. Register here.

Feb. 20 — Diaspora Africa Conference

Come together to hear inspiring speakers, participate in interactive workshops and network with others who are passionate about African heritage and the contributions of the African diaspora. This event will showcase African innovation and allow attendees to connect with funding sources actively seeking high-growth opportunities in Africa.

This event is Thursday, Feb. 20, from 9 a.m.–6 p.m. at the Ion. Register here.

Feb 20–21 — TMC AI Summit 2025

The TMC AI Summit aims to translate advanced AI innovations into practical solutions for real-world biomedical and health care challenges by bringing together researchers, clinicians, and industry leaders. The event features various workshops and tracks with keynote speakers from Rice University, UTHealth, Microsoft Health Futures and other organizations.

This event is Thursday, Feb. 20, from noon–7 p.m. and Friday, Feb. 21, from 8 a.m.–5 p.m. at TMC Helix Park in the TMC3 Collaborative Building. Register here.

Feb. 25 — Houston Methodist Leadership Speaker Series at Ion - Tesha Montgomery

Hear from Houston Methodist’s SVP of System Patient Access about how the health care system is approaching improvements to patient access and highlighting women in health care leadership. Audiences can participate in a 30-minute discussion following Montgomery’s remarks.

This event is Tuesday, Feb. 25, from 4:45–6 p.m. at the Houston Methodist Tech Hub at the Ion. Register here.

Feb. 26 — Inaugural HTX AgTech Rodeo Innovation Summit 2025

Network with farmers, founders, startups and investors at the first-ever HTX AgTech Rodeo Innovation Summit. The all-day event will feature panels, fireside chats, a Saddle Up Pitch Competition and reception with live music.

This event is Wednesday, Feb. 26, from 8:30 a.m.–8 p.m. Find more information and register here.

Feb. 27 — NASA Tech Talks

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges challenges NASA’s Johnson Space Center and the larger aerospace community are facing and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.


This event is Thursday, Feb. 27, from 6-7 p.m. at the Ion. Register here.

Feb. 27–28 – QVIDTVM x The Ion: Inaugural Hack Day Competition

Investment firm QVIDTVM and the Ion are calling all data scientists, analysts, developers and innovators to a new hack day. Participants will aim to find the total value of real estate platformed by Airbnb globally and can participate in a Fireside Chat on AI with Nick King, founder and CEO of Data Kinetic. Teams can include up to four people and prizes for first through third place will be awarded.

This event is Thursday, Feb. 27, at 9:30 a.m. until Friday, Feb. 28, at 5 p.m. at the Ion. Register here.


Don't miss these January events — from meetups to scale ups. Photo via Getty Images

10+ can't-miss Houston business and innovation events for January

WHERE TO BE

From networking meetups to tech talks, January is filled with opportunities for Houston innovators. Here's a roundup of events you won't want to miss out on so mark your calendars and register accordingly.

Note: This post might be updated to add more events.

January 3 — Cup of Joey Networking

Create a connected culture of coffee shop-open networking across our region. Every Friday morning, you’ll have the opportunity to meet new people and expand your current networks, talk about tech, inspire innovation, and create community.

This event is Friday, January 3, from 8:30 to 10:30 am at the Ion. Click here to register.

January 7 — Discover Your Creative Goldmine: The Millions are in your Micro-Niche

In this high-energy workshop, you’ll learn how identifying and embracing your unique micro-niche can simplify your business and fast-track your success. Through a dynamic mix of strategy and mindset mastery, you’ll leave equipped with actionable insights to transform your brand. Don’t miss this opportunity to align your business for growth and connect with like-minded creatives.

This event is Tuesday, January 7, from 12:30 to 1:30 pm at SheSpace. Click here to register.

January 15 — Angel Investing 101: Introduction to Angel Investing

Join the Urban Capital Network team for an evening of learning, discussion and possibilities as we explore the basics of angel investing and the role it plays in bringing new products and services to market and the impact it has on wealth and job creation. At this event, you’ll learn the key components to successfully navigate the critical-path of investing in private, early-stage companies.

This event is Wednesday, January 15, from 5:30 to 6:30 pm at the Ion. Click here to register.

January 15 — In the Age of the Humanoid Robot

Persona AI cofounder & seasoned roboticist Nicolaus Radford will discuss the promise of embodied AI and the adoption of humanoid robots—two advancements likely to impact every market sector. Humanoids coupled to artificial intelligence are poised to reshape the global work landscape; to learn more, check out the Q&A, and Second Draught happy hour.

This event is Wednesday, January 15, from 5 to 7 pm at the Ion. Click here to register.

January 16 — NAWBO Houston Conference: The Power of Women in Business 2025

This event is your opportunity to connect with influential speakers, successful entrepreneurs, and industry experts who are shaping the future of business. From inspiring keynotes to thought-provoking panels, this conference is designed to provide attendees with actionable insights and strategies to elevate their careers.

This event is Thursday, January 16, from 9 am to 3 pm at Norris Conference Centers - Houston/CityCentre. Click here to register.

January 16 — Houston Methodist Innovation TechHub Event

Join the Houston chapter of the Healthcare Information and Management Systems Society for a discussion on the Houston Methodist TechHub, innovative ideas, and a tour of the Ion.

This event is Thursday, January 16, from 5:30 to 7:30 pm at the Ion. Click here to register. 

January 21 — 2025 Female Founders & Friends

This Sesh Coworking event brings together female founders, funders and allies looking for connections with other like-minded go-getters in the Houston community. Connect over coffee with like-minded individuals

This event is Tuesday, January 21, from 9 to 10:30 am at Sesh Coworking. Click here to register.

January 23 — NASA Tech Talks

Discover NASA’s toughest tech challenges–and apply your skills and expertise to solve them.In these presentations, occurring the fourth Thursdays of the month, Mr. Montgomery Goforth and other aerospace subject matter experts will discuss the technology development challenges faced by NASA’s Johnson Space Center and the surrounding Aerospace community in our ongoing efforts as the hub of human spaceflight. Presentations will focus on the ways in which these challenges, and the associated opportunities, can be leveraged by Houston’s innovation community

This event is Thursday, January 23, from 6 to 7 pm at the Ion. Click here to register.

January 28 — Texas Small Business Expo

Texas Small Business Expo is a premier trade show, educational business to business conference, exhibition, and networking event for entrepreneurs, startups and anyone that owns a business, or looking to start their own business. The focus of the conference is targeted on networking, building new business relationships and learning from Industry Experts on how to enhance your business.

This event is Tuesday, January 28, from 4 to 9 pm at the Bell Tower on 34th. Click here to register.

January 30 —TiE Houston's Investing in the Age of AI

For those involved in AI-driven innovation, building new companies, leading established businesses, or exploring investment opportunities in AI, this event is designed for you. Moderated by Sammy Haroon, founder and CEO of AlphaX Decision Sciences, speakers at this event include Major Tony Cucolo, CEO of PCSI, and Yashwanth Hemaraj, general partner at BGV.

This event is Thursday, January 30, from 6 to 9 pm at the Junior League of Houston. Click here to register.

January 31 — Greater Houston Partnership 2025 Meeting

This signature event brings together business and community leaders from across our region to celebrate achievements and set the course for an even brighter future. The Greater Houston Partnership will welcome incoming Board Chair Gretchen Watkins, President, Shell USA, Inc., and honor the contributions of outgoing chair Eric Mullins, as well as present several prestigious awards that highlight the exceptional leadership driving Houston forward.

This event is Friday, January 31, from 11 am to 1:30 pm at Hilton Americas Houston. Click here to register.


Here are four ways to look out for the women at your company. Photo via Getty Images

Houston expert: 4 ways to continue supporting women in the workplace

Guest column

Fresh from the nation celebrating Mother’s Day last weekend weekend, recognizing the valuable role women play in raising their families, it is also an appropriate time to reflect upon the struggles women continue to face in a post-pandemic workplace. Women are juggling remote/hybrid schedules along with schooling dilemmas and a decline in childcare options, expediting burnout and fueling the “Great Resignation,” which continues to be a concern as the number of quits in March reached a record high of 4.5 million.

According to a recent Deloitte report, Women @ Work 2022: A Global Outlook, over 50% of women plan to quit their jobs in the next two years due to burnout. In addition, 53% of women say their stress levels are higher than they were a year ago; 46% say they feel burned out; nearly half rated their mental health as poor or very poor; only 43% feel comfortable talking about mental health challenges in the workplace; and 47% rated work-life balance as poor or extremely poor.

These are alarming statistics, but the challenges are not insurmountable as employers work to attract and retain top talent. Below are four ways savvy leaders can support women and working parents in the workplace.

Promote work-life balance

With many employees feeling burned out and exhausted from an extended period of working longer hours and handling schooling/caregiving responsibilities, it is crucial for leaders to promote work-life balance to help alleviate further repercussions and restore equilibrium. While encouraging employees to use allotted paid time off (PTO) and paid volunteer hours are significant ways, there are smaller steps that can add up to big differences in achieving work-life balance. Leaders should encourage employees to step away from their screens by taking daily breaks, enjoying lunch hours, starting/ending the workday on time and refraining from after-hours emails. Leaders should also set an example by practicing what they preach to attain work-life balance. Finding opportunities to unplug via PTO, volunteering and brief amounts of time each day can help employees feel refreshed and focused when they do return to their screens. When employees have work-life balance, it can give them a new perspective and make their jobs feel more rewarding as they pursue their careers.

Support career growth

One of the most important ways to support employees is to offer professional development programs that support career growth and lead to advancement opportunities within the company. Leaders should work with employees to define a career path that supports their career goals and aspirations and identify the best tools/resources required to accomplish their objectives. Professional development programs should offer a variety of resources that align with individual/business objectives, such as on-the-job training, supervisory instruction, formal mentoring programs, instructor-led courses, online learning and conferences to help employees learn in a well-rounded manner that supports varying learning styles. In addition, employers can further demonstrate their support for the growth and educational needs of employees by offering tuition reimbursement programs. When employees have a chance to expand their skill sets and continue to learn/grow, they are more engaged and connected to the company and less likely to seek opportunities elsewhere.

Boost well-being efforts

As employee mental health/wellness has moved to the forefront at many companies, leaders are boosting their efforts to improve, expand or change aspects of their employee well-being programs to address the needs and expectations of the workforce. While generous PTO programs, paid volunteer time, EAPs, mindfulness programs and meditation apps are a solid start, companies should go further by taking a more holistic approach to well-being by weaving it into the company’s DNA. Well-being should be a consideration in all aspects of business operations – from branding and productivity to performance and purpose – facilitating endless opportunities to view the business through a health and wellness lens. In addition, employers that realize many factors influence employees’ lives and their overall health, such as purpose/career, social, financial, physical, community and mental/emotional are displaying their commitment to employee wellness and positioning their companies for long-term success.

Offer relevant perks

The stress related to financial concerns can lead to employee burnout and mental health issues, so leaders should identify ways to help ease some of the monetary burden. Although some expenses may decrease in a remote/hybrid work environment, others might increase in areas such as home/office equipment purchases, office supplies, higher utility bills and child/elder care expenses, causing additional employee stress. When employers offer relevant perks to offset some of these costs, including company-sponsored discounts, gift cards for office supply companies, partial reimbursement for internet service, assistance with child/elder care expenses, raffles for monthly house cleaning, dog-walking or laundry services, or lunches via a food delivery service they are demonstrating care and concern for employees.

While Mother’s Day is only celebrated once a year, the struggles that women and working parents face daily should be a topic of conversation that is elevated and ongoing in boardrooms across the country. As increasing numbers of working parents and employees experience burnout and mental health concerns that may lead to further resignations, it is imperative for business leaders to combat the situation by promoting work-life balance, supporting career growth, boosting well-being efforts and offering relevant perks.

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Jill Chapman is a senior performance consultant with Insperity, a leading provider of human resources and business performance solutions.

At a conference focused on women in business, three Houston entrepreneurs gave their advice for the next generation of female innovators. Photo by Scott Halleran/Getty Images

Overheard: Houston female entrepreneurs share advice and experience

Eavesdropping in Houston

Hundreds of women gathered for the Greater Houston Women's Chamber of Commerce's annual Greater Houston Conference for Women. The full-day event on April 18th shined a spotlight on the work women are doing in business in the Bayou City.

One part of the programing included a panel of three Houston entrepreneurs who told their stories and meant to inspire the next generation of businesswomen.

"Innovation is critically important to our city," says Tandra Jackson, KPMG's Houston office partner and moderator of the panel. "Having an ecosystem where we bring innovative capabilities, solutions, and organizations to our community is absolutely paramount to the longevity of our city."

If you missed the event, here are some powerful quotes overheard at the panel.

“I look for a passionate entrepreneur with a point of difference — there’s got to be a reason for you to be doing this company. What are you bringing to [the industry]?”

—Janet Gurwitch, founder of Laura Mercier Cosmetics and private equity investor focused on cosmetics companies, when asked if there was a difference between male and female entrepreneurs. "Other than biologically, no," she says.

“It’s extraordinarily important that you find an investor who basically gets it — whether it’s the financial [concern of] how to you do revenue recognition in the software world, or how do you capitalize and understand the valuations. It’s important that you get the right player.”

— Samina Farid, founder of Merrick Systems Inc., an energy software company when asked about advice for young women interested in starting their own company.

“One of the things I see is [the importance of] really knowing the problem that you solve. When you’re early on, [you have to know] what is the core market that you’re going to serve and is the market large enough that you’re going to attract enough customers to solve that problem.”

— Janette Marx, CEO of Airswift, an international workforce solutions provider. Marx contributes as a mentor in GHWCC's office hours and advises entrepreneurs to look into the program.

Houston-based Work & Mother is rethinking how new mothers pump in the office. Courtesy of Work & Mother

This growing Houston company is revolutionizing the way new mothers pump in the office

Pump it up

A new mom returning to work is probably dreading her new daily inconvenience of taking the time out of the workday to pump her breast milk.

While some employers provide a wellness room to us, but the more likely scenario is that she will have to pump in your car, an empty conference room or the bathroom. And once she is done pumping, she'll have to wash her equipment in the kitchen sink, alongside her coworkers' coffee mugs or dirty Tupperware containers.

One newly launched company mission is to make that scenario a thing of the past.

Work & Mother is a boutique pumping and wellness center that opened its first location in downtown Houston in 2017 and is planning its second downtown location. The 600-square-foot space opened on the first floor of 712 Main St. and offers memberships to companies and individuals, regardless of whether they work in the building.

Abbey Donnell founded the company after speaking with friends who recently returned to work after giving birth.

"There were constant stories about [women] being told the use the IT closet, or the conference room, or the bathroom or their cars," Donnell says. "Some of them were pretty big oil and gas firms companies that should've had the resources and space to do better than that."

Work & Mother offers its members several private pumping rooms, private pumping office spaces, a kitchen area, member lockers and a small retail section where members can buy pumping and wellness equipment. The company's pitch to individual mothers is simple: come to us for privacy and community. But its pitch to companies is more rooted in regulations.

Per the Fair Labor Standards Act Section 7(r), companies with 50 or more employees are required to provide "a place, other than a bathroom, that is shielded from view and free from intrusion from coworkers and the public, which may be used by an employee to express breast milk." Companies that aren't in compliance with Section 7(r) — and lack the resources to do so — can either purchase individual or company memberships to Work & Mother.

"The reception from moms has been incredible," Donnell says. "I've gotten a lot of support from women who are older in their fields, who talk about how [pumping in the office] was a horrible experience for them."

Work & Mother is planning its second location, which will also be in downtown Houston, but Donnell declined to share additional details. When she started the company in 2017, she took minimal investments from friends and family, she says. But in anticipation of the company's second location, Work & Mother will likely launch a pre-seed fundraising round this summer, Donnell says. No financial figures have been finalized, but Donnell says the tentative plan is to raise roughly $1 million.

The company is also hoping to open in cities such as Chicago, New York, Austin, and Dallas in the near future.

Work & Mother isn't targeting companies that are solely concerned about meeting Section 7(r) compliance, Donnell says. Rather, she's hoping to show companies that investing in the well-being of new mothers is essential to running a successful business – and it's the right thing to do.

"If there's an employer who really only cares about the compliance, then they're not exactly a good fit, because they'll convert a closet and check that box," Donnell says.

But what Donnell says she's found refreshing is that most of the companies she's interacted with have had great feedback for her. They're trying to recruit — and retain — top female talent, she says.

More soon

  

Courtesy of Work & Mother

Donnell has plans for a second Houston location, as well as an expansion to other major United States cities.

SeeHerWork launched its line of female-gear in September. Courtesy of SeeHerWork

Houston company aims to equally equip female workers

If the glove doesn't fit

When Jane Henry was working on her home right after Hurricane Harvey — her house got three feet of mud in it — she went to throw a board into the dumpster, and her glove went with it.

Henry says the industry standard is to recommend small and extra-small sizes for women's workwear, but as a ladies large in athletic gloves, Henry still had a good inch or so of glove at her fingertips in her workwear gloves.

"I went upstairs to my sewing room, and I ripped that glove apart and I resewed it to fit my hand," Henry says.

Other women stopped her in hardware stores to ask her about her shoddily sewn glove, and she realized this was the idea for next company. She incorporated SeeHerWork a few months later in January of 2018, and she launched her line of clothing in September, just a year after she had the idea. Based in Houston, SeeHerWork rents warehouse space in Kingwood and has its corporate office in Midtown.

Doing the legwork
Henry is no stranger to the startup game. She created her own consulting company, Xcution Inc., over 16 years ago, but she downsized the company in 2016 when oil prices took a turn. Instead, she went into Rice University's MBA program, where, ultimately, she created a network of associates that would eventually help SeeHerWork grow.

"I've been a serial entrepreneur — been trying to avoid calling myself that," says Henry. "I have two entrepreneurial parents, and I told myself I'd never be an entrepreneur, yet that's what I keep doing."

Through her business expertise and education, she knew she had to start with a one-page business plan for the company. She then took her idea to over 50 focus groups made up of 10 to 20 female workers, safety managers, and procurement managers across industries — transportation, military oil and gas, engineering, and more.

"The response was eerily similar despite the industry," Henry says.

The focus group participants were tired of the "pink it and shrink it" approach to women's workwear and equipment. They felt like if their supplies don't fit, they don't fit. Mentorship opportunities and performance are then subsequently hindered, creating a spiral effect of deterring women from entering the skilled labor workforce. This is a huge problem, considering there's the recent labor shortage with these types of jobs.

She took this information and her first prototypes to a national pitch competition to great success — and a standing ovation. Henry also connected with the Rice Angel Network, Station Houston, The Cannon, and other local innovation-focused entities.

Roadwork ahead
Henry has big plans for SeeHerWork, and is in talks with a few large entities — like the Houston Airport System, Fluor Corp., and Toyota — that have expressed interest in using her gear for their workforce. Henry also wants to expand her products and reach female workers through retail — online and in store.

"Ultimately, SeeHerWork is the Lululemon of workwear," Henry says.

SeeHerWork is focused on keeping women safe, firstly, but also encouraging more women to enter the skilled labor workforce and then work their way up the ladder.

"I don't want people to think of us as a workwear company," Henry says. "I want them to think of us as an inclusion company. Mostly because just like professional sports team, the first step is the right clothing and equipment and the second step is working to be a team and working together."

At your fingertips

  

Courtesy of SeeHerWork

SeeHerWork has a full line of products, from gloves and bags to safety vests and long-sleeves shirts. She's launching more products — like coveralls, pants, and footwear — soon.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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