Rice University researchers unveil new model that could sharpen MRI scans

MRI innovation

New findings from a team of Rice University researchers could enhance MRI clarity. Photo via Unsplash.

Researchers at Rice University, in collaboration with Oak Ridge National Laboratory, have developed a new model that could lead to sharper imaging and safer diagnostics using magnetic resonance imaging, or MRI.

In a study recently published in The Journal of Chemical Physics, the team of researchers showed how they used the Fokker-Planck equation to better understand how water molecules respond to contrast agents in a process known as “relaxation.” Previous models only approximated how water molecules relaxed around contrasting agents. However, through this new model, known as the NMR eigenmodes framework, the research team has uncovered the “full physical equations” to explain the process.

“The concept is similar to how a musical chord consists of many notes,” Thiago Pinheiro, the study’s first author, a Rice doctoral graduate in chemical and biomolecular engineering and postdoctoral researcher in the chemical sciences division at Oak Ridge National Laboratory, said in a news release. “Previous models only captured one or two notes, while ours picks up the full harmony.”

According to Rice, the findings could lead to the development and application of new contrast agents for clearer MRIs in medicine and materials science. Beyond MRIs, the NMR relaxation method could also be applied to other areas like battery design and subsurface fluid flow.

“In the present paper, we developed a comprehensive theory to interpret those previous molecular dynamics simulations and experimental findings,” Dilipkumar Asthagiri, a senior computational biomedical scientist in the National Center for Computational Sciences at Oak Ridge National Laboratory, said in the release. ”The theory, however, is general and can be used to understand NMR relaxation in liquids broadly.”

The team has also made its code available as open source to encourage its adoption and further development by the broader scientific community.

“By better modeling the physics of nuclear magnetic resonance relaxation in liquids, we gain a tool that doesn’t just predict but also explains the phenomenon,” Walter Chapman, a professor of chemical and biomolecular engineering at Rice, added in the release. “That is crucial when lives and technologies depend on accurate scientific understanding.”

The study was backed by The Ken Kennedy Institute, Rice Creative Ventures Fund, Robert A. Welch Foundation and Oak Ridge Leadership Computing Facility at Oak Ridge National Laboratory.

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The Welch Foundation has awarded funding through two of its newest grant programs. Photo via Getty Images.

Houston foundation doles out $700K for Texas chemical research

fresh funding

Houston-based The Welch Foundation has issued $700,000 in additional funding to support chemical research through two of its newest grant programs.

The foundation has named the recipients of its Welch eXperimental (WelchX) Collaboration Retreat and Pilot Grants and the Welch Postdoctoral Fellows of the Life Sciences Research Foundation Grants.

The WelchX grants were awarded to teams of two Texas researchers who presented "innovative and collaborative ideas" addressing challenges in the clean energy space, according to the foundation.

Researchers from Texas universities gathered in Houston earlier this summer to discuss the theme “Chemical Research for Grand Challenges." They then paired off into nine teams and submitted proposals for the $100,000 pilot grants. The seven selected teams, several with ties to Houston, and their research topics include:

  • Yimo Han, Rice University, and Yuanyue Liu, The University of Texas at Austin, “Stabilizing Copper Electrocatalysts for CO2 Conversion”
  • Ognjen Miljanic, University of Houston, and Indrajit Srivastava, Texas Tech University, “Ping-Pong' Afterglow Luminescence in Self-Assembled Molecular Cubes”
  • Raúl Hernández Sánchez, Rice University, and Andy Thomas, Texas A&M University, “Accelerating Magnetic Resonance Imaging Contrast Agent Discovery via Rapid Injection NMR: Improving the Detection of Lithium for Disease Diagnostics”
  • Benjamin Janesko, Texas Christian University, and MD Masud Rana, Lamar University, “Cyber Twin Chemical Ensembles for Near-Infrared-Emitting Graphene Quantum Dot Therapeutics”
  • Ivan Korendovych, Baylor University, and Dino Villagrán, The University of Texas at El Paso, “Selective Bio-Inspired Electrochemical Probes for PFAS Analysis and Degradation”
  • Samantha Kristufek, Texas Tech University, and Kayla Green, Texas Christian University, “CIRCUIT: Critical Ion Recovery using Conductive and Ultrafiltration Intelligent Technology”
  • Fang Xu, The University of Texas at San Antonio, and Hong Wang, University of North Texas, “Visualize Molecular Adsorption on Supported Ni-porphyrin Model Catalysts via Substitute Effect”

The Welch Postdoctoral Fellows of the Life Sciences Research Foundation provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas.

The foundation previously announced that it would name fellows from Rice University and Baylor University who would receive $100,000 annually for three years. This year's recipients and their research topics include:

  • Teng Yuan, Rice University, “Unlocking New Chemistry of Nonheme Iron Enzymes for α-Amino Acids and γ-Lactones Synthesis”
  • Katelyn Baumler, Baylor University, "Crystal Growth of Ln2Fe4Sb5 Phases Toward the Study of Novel Quantum Properties”

“As these programs become more established, it is thrilling to see the new research our awardees are exploring,” Adam Kuspa, president of The Welch Foundation, said in a news release. “The Foundation is very pleased by the applications that we continue to receive describing exciting new research projects to advance chemical research.”

This additional funding comes on the heels of the foundation doling out $27 million for chemical research, equipment and postdoctoral fellowships earlier this summer. The foundation made 85 grants to faculty at 16 Texas institutions at the time. Read more here.

In all, the Welch Foundation on June 4 announced more than $40.5 million in academic research grants, equipment grants, and fellowships. Photo via Getty Images

Texas organization grants over $40M to chemistry research in Houston and beyond

fresh funding

Two local professors are among the newly announced recipients of funding from the Houston-based Welch Foundation, which finances chemical research projects.

The two professors are:

  • Jacinta Conrad, the Frank M. Tiller Professor in the Chemical and Biomolecular Engineering Department at the University of Houston. Conrad will use her grant to investigate glass transition, a temperature change that affects polymers. She describes glass transition as one of the “most intriguing open problems in physical chemistry.”
  • James Shee, assistant professor in the Chemistry Department at Rice University. Shee will put his grant toward advancing theoretical chemistry.

Every year, the foundation provides annual grants totaling at least $100,000 to support chemistry research being carried out by full-time faculty members at colleges, universities, and other educational institutions in Texas.

In all, the Welch Foundation on June 4 announced more than $40.5 million in academic research grants, equipment grants, and fellowships.

Part of the announced funding will go toward the foundation’s new Postdoctoral Fellows Grant Program. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. A total of $900,000 in postdoctoral fellowships were funded at Rice University, Texas A&M University, and the University of Texas at Austin.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs, and other chemistry-related ventures.

“Ongoing basic chemical research is critically important for helping to solve current and future problems,” said Adam Kuspa, President of the Welch Foundation. “We strongly believe the foundation’s continued support of the research grant program, combined with … new programs, will yield even more exciting developments as we work to advance chemistry and improve our lives.”

With this new grant, UH has a new center for researching bioactive materials crystallization. Photo via UH.edu

Houston innovator receives $5M to establish new center that explores crystallization process

crystal clear initiative

A new hub at the University of Houston is being established with a crystal-clear mission — and fresh funding.

Thanks to funding from Houston-based organization The Welch Foundation, the University of Houston will be home to the Welch Center for Advanced Bioactive Materials Crystallization. The nonprofit doled out its inaugural $5 million Catalyst for Discovery Program Grant to the new initiative led by Jeffrey Rimer, Abraham E. Dukler Professor of Chemical Engineering, who is known internationally for his work with crystals that help treat malaria and kidney stones.

“Knowledge gaps in the nascent and rapidly developing field of nonclassical crystallization present a wide range of obstacles to design crystalline materials for applications that benefit humankind, spanning from medicine to energy and the environment,” says Rimer in a news release. “Success calls for a paradigm shift in the understanding of crystal nucleation mechanisms and structure selection that will be addressed in this center.”

The Welch Foundation, which was founded in 1954, has granted over $1.1 billion to scientists in Texas. This new grant program targets researchers focused on fundamental chemical solutions. Earlier this year, the organization announced nearly $28 million in grants to Texas institutions.

"Support from the Welch Foundation has led to important advances in the field of chemistry, not only within Texas, but also throughout the United States and the world as a whole,” says Randall Lee, Cullen Distinguished University Chair and professor of chemistry, in the release. “These advances extend beyond scientific discoveries and into the realm of education, where support from the Welch Foundation has played a significant role in building the technological workforce needed to solve ongoing and emerging problems in energy and health care.”

Rimer and Lee are joined by the following researchers on the newly announced center's team:

  • Peter Vekilov, Moores Professor, chemical and biomolecular engineering
  • Alamgir Karim, Dow Chair and Welch Foundation Professor, chemical and biomolecular engineering;
  • Jeremy Palmer, Ernest J. and Barbara M. Henley Associate Professor, chemical and biomolecular engineering
  • Gül Zerze, chemical and biomolecular engineering
  • Francisco Robles Hernandez, professor of engineering technology.

The University of Houston also received another grant from the Welch Foundation. Megan Robertson, UH professor of chemical engineering, received $4 million for her work with developing chemical processes to transform plastic waste into useful materials.

“For the University of Houston to be recognized with two highly-competitive Welch Foundation Catalyst Grants underscores the exceptional talent and dedication of our researchers and their commitment to making meaningful contributions to society through discovery,” Diane Chase, UH senior vice president for academic affairs and provost, says in the release.

The Welch Foundation, a Houston-based nonprofit, has doled out fresh funding to research organizations, with over a third being deployed to Houston-area institutions. Photo via Getty Images

Houston organization announces nearly $28M in Texas research grant funding

money moves

Five schools in the Houston area have landed $10.8 million in research grants from the Houston-based Welch Foundation.

The 36 grants were awarded to Rice University, Texas A&M University, the University of Houston, the Baylor College of Medicine, and the University of Texas Medical Branch in Galveston.

In all, the foundation announced nearly $28 million in Texas research grants for 2023. All of the money — in the form of 91 grants for 15 Texas colleges and universities — goes toward chemical research. This year’s total for grant funding matches last year’s total.

“The Welch Foundation continues to emphasize the creative pursuit of basic chemical research,” Adam Kuspa, the foundation’s president and a former dean at the Baylor College of Medicine, says in a news release. “Our funding allows investigators throughout the state to follow their curiosity and explore the foundations chemical processes.”

Since its establishment in 1954, the Welch Foundation has contributed about $1.1 billion to the advancement of chemistry in Texas.

One of this year’s local grant recipients is Haotian Wang, assistant professor in Rice’s chemical and biomolecular department. The professor’s grant-funded research will focus on the conversion of carbon dioxide into useful chemicals, such as ethanol.

Last year, Rice reported that Wang’s lab in the George R. Brown School of Engineering had replaced rare, expensive iridium with ruthenium, a more abundant precious metal, as the positive-electrode catalyst in a reactor that splits water into hydrogen and oxygen.

The lab’s addition of nickel to ruthenium dioxide resulted in production of hydrogen from water electrolysis for thousands of hours.

“There’s huge industry interest in clean hydrogen,” Wang says. “It’s an important energy carrier and also important for chemical fabrication, but its current production contributes a significant portion of carbon emissions in the chemical manufacturing sector globally.”

“We want to produce it in a more sustainable way,” he adds, “and water-splitting using clean electricity is widely recognized as the most promising option.”

Lane Martin will lead the Rice Advanced Materials Institute beginning this summer. Photo courtesy of Rice

Rice University announces leader of new materials and nanotechnology institute

at the helm

A recently established institute at Rice University has revealed its new leader.

The Rice Advanced Materials Institute has named Lane Martin as director. Martin will also serve as Welch Professor of Materials Science and NanoEngineering in the George R. Brown School of Engineering. He begins both roles on July 1.

“Lane is everything we expect our faculty to be — hard-working, committed to excellence, dedicated to students and collaborative across disciplines,” says Howard R. Hughes Provost Amy Dittmar in a news release. “I look forward to seeing Rice faculty and students reap the benefits of his leadership.”

Prior to his appointment at Rice, Martin was the chancellor’s professor of materials science and engineering at the University of California, Berkeley. He also served as chair of the materials science and engineering department, faculty scientist in the material sciences division of the Lawrence Berkeley National Laboratory, and co-director of the Collaborative for Hierarchical Agile and Responsive Materials, according to the release.

“I had the privilege of mentoring Lane when he was a doctoral student at Berkeley,” says Ramamoorthy Ramesh, vice president for research, professor of materials science and nanoengineering and professor of physics and astronomy. “He is a gifted scientist with the boldness and vision to build this new institute into a research powerhouse.”

The new institute was created following a $100 million gift from Houston-based Welch Foundation. It will bring together chemistry, materials science, machine learning, and artificial intelligence to revolutionize the future of industry.

“This institute will keep Rice at the forefront of high-impact research related to energy transition, advanced materials and future computing,” says Luay Nakhleh, the William and Stephanie Sick Dean of the school, in the release. “It will empower our faculty and students to help solve some of the most pressing problems of our day.”

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Intuitive Machines lands $600M satellite deal, NASA ‘spacecraft bus’ contract

space deals

Houston-based space infrastructure company Intuitive Machines has scored two astronomical deals.

The deals add to the company’s soaring success. As of June 30, Intuitive Machines had a record-high $1.8 billion backlog of orders, a $1.5 billion increase from the end of last year. The current backlog includes orders for more than 80 spacecraft.

The company, which went public in 2023, expects this year’s revenue to total $900 million to $1 billion. In the first half of 2026, Intuitive Machines generated nearly $393 million in revenue.

Intuitive Machines estimates its total available market is valued at more than $150 billion.

$600 million-plus deal represents ‘important milestone’

On Monday, Intuitive Machines said it picked up a $600 million-plus deal to develop three commercial satellites for an undisclosed customer over the course of about two years.

Intuitive Machines says it will design, manufacture, set up and support several spacecraft “for a critical communications infrastructure mission.”

Steve Altemus, the company’s CEO, says the deal represents “an important milestone for Intuitive Machines and reflects the confidence our customers place in our ability to deliver high-performance spacecraft for a broad range of mission needs.”

Company nails down NASA deal for ‘spacecraft bus’

A day after announcing the $600 million-plus deal, Intuitive Machines said it secured a new contract with NASA.

Intuitive Machines says NASA’s Jet Propulsion Laboratory in Southern California will use the company’s IM 300 “spacecraft bus” for an EAGLE-VSWIR Earth observation mission. The mission is scheduled to launch in 2028.

Aside from supplying the IM 300 bus, Intuitive Machines will carry out mission support services.

The low-Earth-orbit mission will be equipped with Intuitive Machines’ hyperspectral visible to shortwave infrared (VSWIR) instrument. This technology sees colors and details that aren’t visible to the human eye.

The instrument is “designed to perform surface biology and geology observations from Earth orbit while demonstrating technologies that could support future lunar and Mars exploration missions,” Intuitive Machines says.

Intuitive Machines builds mission-critical spacecraft, systems, and infrastructure for business and government customers. To date, the company has produced more than 300 spacecraft, delivered over 575 pounds of payload to the moon and launched about 100 satellites.

9 Houston-based companies make Fortune Global 500 list in 2026

Worldwide Rankings

Nine Houston companies landed on the 2026 Fortune Global 500 list, which ranks the world's largest corporations by revenue for the 2025 fiscal year.

Houston's showing on the list was led by energy companies, with Spring’s ExxonMobil claiming the top local spot. Here’s what Houston-area companies made the list, and where they ranked:

  • No. 15 ExxonMobil
  • No. 36 Chevron
  • No. 61 Phillip 66
  • No. 159 Sysco
  • No. 243 ConocoPhillips
  • No. 292 Enterprise Products Partners
  • No. 343 Plains GP Holdings
  • No. 460 SLB
  • No. 481 Hewlett Packard Enterprise

After 12 years as No.1, Arkansas-based Walmart was replaced this year by Seattle-based Amazon in the top spot for 2026. Amazon achieved this by bringing in $700 billion in revenue in 2025, representing a 12 percent increase from the previous year.

"Across global business, we see again and again that the leaders who are winning are those who embrace change,” Alyson Shontell, Fortune's editor in chief and chief content officer, said in a news release. "Amazon has topped the Fortune Global 500, knocking Walmart off its pedestal. The company has continually reinvented itself across new businesses and bold bets—including a $200 billion capital commitment, largely to building its capacity for AI and cloud computing, in this year alone."

The U.S. has 141 companies on the 2026 Fortune Global 500 list, which is the most of any country. Companies in America generated $15.5 trillion in aggregate revenues, a 6 percent increase from the previous year.

The number of women CEOs at Fortune Global 500 companies reached a record of 34 top leaders, who represented 6.8 percent of CEOs of companies on the list.

Technology was the standout growth industry on this year’s list, with 38 companies earning revenues that grew 20 percent to about $4 trillion in 2025, with profits climbing 36 percent to $835 billion. The financial sector accounted for the largest share of companies on the list again, with 123 companies in that sector. The energy sector claimed the No. 2 industry spot with 77 companies making the list.

In June, the Fortune 500 list was released, and Texas led the United States with 57 Fortune 500 companies headquartered in the state, generating $2.8 trillion in combined revenue.

Fast-growing Houston real estate startup surges to No. 7 on Inc. 5000

growth report

Houston-based Epique Realty has ridden the AI wave to rank among the Inc. 5000’s 10 fastest-growing private companies.

With three-year revenue growth of 23,210 percent, the AI-powered real estate brokerage appears at No. 7 on this year’s Inc. 5000 list. The 2026 list ranks private companies based on percentage revenue growth from 2022 to 2025.

Epique, founded in 2021, also ranks as the No. 1 fastest-growing company in Houston, No. 1 fastest-growing real estate company in the U.S., and No. 2 fastest-growing company in Texas.

Epique’s annual revenue surpasses $91 million

Between 2022 and 2025, the company’s annual revenue skyrocketed from $391,654 to more than $91.2 million. In 2025, the brokerage closed more than 23,000 deals and surpassed $7 billion in total sales, elevating Epique to the country’s 14th-largest real estate brokerage as measured by volume.

Epique’s network has more than 4,000 agents.

“To debut in the top 10 of the Inc. 5000 is absolute proof that when you relentlessly put agents first, exponential growth takes care of itself,” co-founder and CEO Joshua Miller said in a news release.

“We didn’t achieve this by following the industry playbook; we achieved this by burning it,” Miller added. “By fully funding our agents’ success through free health care, proprietary AI, and world-class leads, we’ve built a company where agents can finally thrive.”

The company’s other co-founders are Chris Miller, chief operating officer and vice president of expansion, and Janice Delci, chief financial officer.

Epique expands business to Canada, Mexico, Australia

The Millers and Delci have guided the company’s rapid expansion.

“Scaling our corporate support team to match [our] hyper-growth while seamlessly expanding across all 50 states and internationally to Canada, Australia, and Mexico takes an incomparable operational infrastructure,” Miller said.

“We have built an enterprise-grade technology ecosystem that allows us to absorb overhead and empower our agents at lightning speed,” he added. “This ranking validates that our disruptive model is working, and it is completely redefining the global industry standard.”

Epique launched its platform in 2023, touting itself as the industry’s first AI-powered brokerage. The startup’s platform provides AI tools for real estate agents to improve their marketing, streamline content creation, and boost engagement with clients and prospects.

Among Epique’s AI tools are:

  • ChatGPT for generation of property descriptions
  • AI-assisted creation of blog posts and agents’ bios
  • Production of Instagram quotes for social media marketing

“When we started Epique, we wanted to build a company that genuinely cared for its agents’ financial and physical well-being,” Delci says. “To see that vision translate into this level of historic record-breaking growth is a beautiful testament to the true power of radical generosity.”

Epique and fellow honorees will be recognized Oct. 14-16 at the 2026 Inc. 5000 Conference & Gala in Dallas.

Six other Houston-area companies land in top 250

Here are the six other Houston-area companies that claimed spots in the top 250 on the Inc. 5000 list. Each company name is followed by its ranking, headquarters city, and three-year growth rate.

  • No. 27 Empact Technologies, 8,275 percent
  • No. 60 Action1, 4,512 percent
  • No 75 Signs By G, 3,684 percent
  • No. 79 The ’Pause Life, 3,469 percent (Galveston)
  • No. 110 Turtlebox Audio, 2,576 percent
  • No. 178 Dahnani Private Equity Group, 1,904 percent (Stafford)

How did companies in Texas’ other major metros fare?

Here’s a breakdown of companies in the Austin, Dallas-Fort Worth, and San Antonio areas that made the top 250 on the Inc. 5000. Again, each company name is followed by its ranking, headquarters city, and three-year growth rate.

Austin (10 companies)

  • No. 9 Investment Watches, 15,741 percent
  • No. 72 Razor Metrics, 3,856 percent
  • No. 91 Autonomize AI, 2,921 percent
  • No. 102 Choose Your Horizon, 2,719 percent
  • No. 132 Wander Staffing, 2,296 percent
  • No. 144 Everyday Dose, 2,179 percent
  • No. 148 NetRise, 2,118 percent
  • No. 163 Nutrabound Labs, 1,999 percent (Bastrop)
  • No. 179 Steadily, 1,890 percent
  • No. 208 Tiny Health, 1,624 percent

Dallas-Fort Worth (11 companies)

  • No. 3 Yantran, 258,740 percent (Allen)
  • No. 12 Paek Management Group, 12,520 percent (Irving)
  • No. 82 Elite Robotics and Automation, 3,334 percent (Fort Worth)
  • No. 133 Outamation, 2,291 percent (Southlake)
  • No. 147 Red Creek Solutions, 2,119 percent (Frisco)
  • No. 155 JobTread Software, 2,071 percent (Dallas)
  • No. 164 DAX Eyewear, 1,977 percent (Nevada)
  • No. 186 Optimized Waste Removal, 1,830 percent (Fort Worth)
  • No. 204 Freight Flex, 1,642 percent (Denton)
  • No. 212 Maverick Power, 1,591 percent (McKinney)
  • No. 229 Innovative Life Sciences, 1,494 percent (McKinney)

San Antonio (one company)

  • No. 118 Hire With Near, 2,421 percent
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