Vonlane will get travelers from The Woodlands to Dallas in just over three hours. Courtesy photo

Houston-area business and leisure travelers have a convenient new route to check out thanks to Vonlane. The Texas-based luxury motor coach service is adding a new daily service between The Woodlands and Dallas starting June 13.

Vonlane already offers service between Dallas and downtown Houston, at the Hyatt Regency at 1200 Louisiana St., eight times per day starting at 6 am. The ride takes 3 hours and 45 minutes.

According to Vonlane founder and CEO Alex Danza, The Woodlands has been a much-requested route.

“The Woodlands area has been our most requested geographic addition for several years, so we’re thrilled to announce this expansion, our 10th destination on our 11th anniversary,” Danza says. “Bringing our elevated bus service to suburban areas is a strategic priority as we seek to relieve the hassles of driving and air travel for our passengers and better meet them where they live, work, and play.”

The new service brings a convenient nonstop route to and from the northern fringe of Houston — The Woodlands, Spring, Cypress, Conroe, Montgomery County, and northern Harris County.

Beginning June 13, The Woodlands-Dallas route will offer the following departures:

  • Monday, Thursday, and Friday: 6:15 am, 10:15 am, 2:15 pm, and 6:15 pm – departing both The Woodlands and Dallas
  • Tuesday, Wednesday, and Sunday: 10:15 am and 2:15 pm – departing both The Woodlands and Dallas
  • Saturday: 9 am: departing The Woodlands
  • Saturday 1 pm: departing Dallas

This ride will take 3 hours and 15 minutes.

The new drop-off point for The Woodlands service will be at Woodlands Waterway Marriott Hotel & Convention Center, 1601 Lake Robbins Dr.. According to Danza, The Woodlands Waterway Marriott offers easy access to I-45, ample parking, and high-quality accommodations.

Riders will depart in Dallas at the established stop at Doubletree Love Field, 3300 W. Mockingbird Ln. The new route offers proximity to major employers in the area such as Alight Solutions, Baker Hughes, Chevron Phillips, Entergy, ExxonMobil, Hewlett-Packard, Houston Methodist, Huntsman Corporation, Lone Star College, McKesson, Memorial Hermann, Occidental Petroleum, St. Luke’s Health, and Texas Children’s.

Visit The Woodlands president Nick Wolda says in a statement that The Woodlands is a popular destination for Dallas residents.

“Visit The Woodlands is excited to welcome Vonlane to The Woodlands Waterway Marriott and Conference Center. This first-class amenity is a fantastic addition to our vibrant community, perfectly designed to elevate the travel experience,” Wolda says. “The Woodlands is the go-to destination for trips from the DFW area—whether you're a corporate conventioneer, a Pavilion concertgoer, a college student coming home, or a weekend shopping trip with friends. With this new service, getting to and from The Woodlands has never been easier or more enjoyable!"

Vonlane buses have 22 first-class leather seats, ample workspace, complimentary Wi-Fi, and an onboard attendant offering premium cabin service with snacks, meals, and beverages included.

Fares are a flat rate of $125 for one-way trips with advance purchase. No taxes, baggage fees, or change fees apply. Rates increase with less than seven days’ notice and within 24 hours before departure.

Tickets can be booked at www.vonlane.com.

Vonlane was founded in Texas in 2014 and offers more than 475 weekly departures across 10 destinations.

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A version of this story originally appeared on CultureMap.com.

After a weeks-long, COVID-caused intermission, Texas-based Vonlane is hitting highways with daily routes starting July 1. Photo courtesy of Vonlane

Texas bus biz plans to get on the road again

BACK ON TRACK

Vonlane buses are revving their engines again. After weeks without service due to the coronavirus pandemic, the Dallas-based luxury bus operator will restart all routes serving Texas on July 1.

In a June 9 message to customers, Vonlane said daily departures resuming July 1 would include:

  • Houston-Dallas
  • Houston-Fort Worth
  • Houston-Austin
  • Houston-San Antonio
  • Dallas-Austin
  • Dallas-Oklahoma City
  • Fort Worth-Austin

Coming soon are routes to Nashville and Atlanta, with details to be announced, the company says.

As the coronavirus started to cripple travel in March, Vonlane temporarily eliminated four routes serving Texas. "While we are significantly impacted by the circumstances of the day," Vonlane founder and CEO Alex Danza said then. "Our goal is to be a solution for your urgent personal travel."

But by April 15, when most of Texas was sheltering in place, Vonlane suspended operations due to lack of demand. Limited routes between Dallas, Austin, and Houston resumed May 29.

Like many businesses, Vonlane also pivoted its operation in new directions during the shutdown.

On Memorial Day, the company announced it was expanding its services to include out-of-state charters. It now offers bespoke charter service to popular destinations across the continental U.S. like Colorado, Florida, and New Orleans, as an alternative to flying.

Passengers who book a private charter have access to up to 22 seats, can leave from a specific departure point of their choice, and travel to any destination, the company says.

Vonlane also rolled out a parcel shipping service in Texas. "Need to get something to a loved one, friend, or business associate in Austin, Dallas, or Houston today?" Danza said in the announcement. "Send it aboard the next Vonlane departure for a flat fee." More details on the service are outlined here.

In putting its luxury buses back on the road, Vonlane is adopting a number of measures designed to curb the spread of the coronavirus, such as limiting the passenger count to 13 by blocking all aisle seats through June 30; requiring passengers and employees to wear face coverings; and checking passengers' temperatures before boarding.

"As one of our core values, the safety of our passengers, crew, and fellow over-the-road travelers is our top priority," Danza said in a May 26 release announcing the charters. "In light of the current coronavirus situation, Vonlane is maximizing our efforts to make sure the Vonlane experience is as responsible, safe, and comfortable as our passengers have come to expect."

Vonlane launched its high-end bus service in 2014 with the Dallas-to-Austin route. Each bus, which holds fewer than two dozen passengers, features amenities like WiFi, satellite TV and radio, and leather seats.

Reservations can be booked online, and may be canceled and fully refunded up to 24 hours before departure.

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This article originally ran on CultureMap.

Vonlane is now driving beyond Texas. Courtesy photo

Texas travel company revs up for out-of-state expansion

ON THE ROAD AGAIN

In response to pandemic-triggered travel interruptions, Dallas-based high-end bus operator Vonlane is expanding its services to include out-of-state charters and in-state parcel shipping.

In a Memorial Day message to customers, Vonlane founder and CEO Alex Danza said the company now offers charter service to destinations across the continental U.S., citing examples like Colorado, Florida, and New Orleans. Danza says this provides long-distance travel when airline flights aren't an option.

"These bespoke trips allow you to travel privately with your friends, family, and business associates aboard your own Private Jet on Wheels," Danza wrote. "You name the pickup location, destination, and dates while we handle all of the logistics."

Vonlane has also rolled out a same-day parcel shipping service in Texas, where packages basically hitch a ride with the motor coaches.

"Need to get something to a loved one, friend, or business associate in Austin, Dallas, or Houston today?" Danza said. "Send it aboard the next Vonlane departure for a flat fee."

Amid the coronavirus pandemic, Vonlane halted its city-to-city bus service due to a lack of demand. Some routes returned on May 29, including Dallas-Austin, Dallas-Houston, and Houston-Austin.

In putting its luxury buses back on the road, Vonlane is adopting a number of measures designed to curb the spread of the coronavirus, such as limiting the passenger count to 13 by blocking all aisle seats through June 30; requiring passengers and employees to wear face coverings; and checking passengers' temperatures before boarding.

"As one of our core values, the safety of our passengers, crew, and fellow over-the-road travelers is our top priority," Danza says in a May 26 release. "In light of the current coronavirus situation, Vonlane is maximizing our efforts to make sure the Vonlane experience is as responsible, safe, and comfortable as our passengers have come to expect."

Danza says Vonlane hopes to resurrect its Fort Worth, San Antonio, and Oklahoma City routes "as soon as feasible."

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This article originally ran on CultureMap.

Some seats have been blocked to enable social distancing. Courtesy of Vonlane

Texas business-focused bus service curbs routes in response to COVID-19

bus stops

As the coronavirus cripples travel, Dallas-based luxury bus operator Vonlane LLC has temporarily eliminated four routes serving Texas.

In a March 24 email to customers, Vonlane founder and CEO Alex Danza said the four routes that have been paused are:

  • Houston-San Antonio
  • Dallas-Oklahoma City
  • Fort Worth-Austin
  • Fort Worth-Houston

As a result of these changes, no service is currently available to or from Fort Worth.

"While we are significantly impacted by the circumstances of the day," Danza wrote, "we continue to operate a minimal schedule between Austin, Dallas, and Houston as an essential public transportation provider. Our goal is to be a solution for your urgent personal travel."

Once the coronavirus pandemic has subsided, Vonlane will return to its normal schedule of 70 to 78 daily departures in Texas and Oklahoma, according to the email.

For those passengers who travel on Vonlane buses, some seats have been blocked to enable six feet of social distance, Danza wrote. Other coronavirus safety measures include disinfecting bus interiors, stocking buses with hand sanitizer, and outfitting on-board attendants with gloves to wear while serving food and beverages.

"Everyone at Vonlane is excited about the day we see you all aboard the coaches someday soon," Danza wrote.

Vonlane launched its high-end bus service in 2014 with the Dallas-to-Austin route. Each bus, which holds fewer than two dozen passengers, features amenities like WiFi, satellite TV and radio, and leather seats.

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This article originally ran on CultureMap.

Traveling by bus has never been more comfortable with Vonlane's high-end amenities. Courtesy of Vonlane

Growing Texas luxury bus line expands Houston-to-San Antonio service

Riding in style

A growing luxury bus line that's set the standard for upscale road tripping across the Lone Star State has just expanded its services.

Since launching in 2015, Dallas-based Vonlane has been lauded for its first-class seats and high-end amenities, from on-board attendants and complimentary refreshments to free Wi-Fi, noise-cancelling headphones, and in-route entertainment options at each seat.

The custom-configured coaches feature just 22 first-class seats as opposed to the 56 seats of a similarly sized charter bus, allowing each passenger far more space than one would find on a commercial airplane — not to mention that tickets are competitively priced — with one-way tickets ranging around the $100 mark.

The Texas-based service has operated lines with stops in Houston, Dallas, Fort Worth, Austin, and San Antonio for years. Now, beginning September 9, Vonlane will begin operating its luxury travel line between Houston and San Antonio via new terminals. Travelers can catch the first-class bus at the Hyatt Regency Houston Galleria (2626 Sage Rd.) and arrive at the Marriott Rivercenter in San Antonio (101 Bowie St.) roughly three hours later.

With buses departing four times a day on Monday, Wednesday, Thursday, and Friday, as well as twice on Tuesday, once on Saturday, and twice on Sunday, the service is ideal for both business and leisure travelers looking for a well-appointed transportation option without the cost or hassle of an airline.

Every seat on a Vonlane bus offers first-class luxury. Courtesy of Vonlane

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This article originally ran on CultureMap.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.